HRP20050735B1 - Dihidropteridinoni, metoda za njihovu proizvodnju i upotrebu u obliku lijekova - Google Patents

Dihidropteridinoni, metoda za njihovu proizvodnju i upotrebu u obliku lijekova

Info

Publication number
HRP20050735B1
HRP20050735B1 HRP20050735AA HRP20050735A HRP20050735B1 HR P20050735 B1 HRP20050735 B1 HR P20050735B1 HR P20050735A A HRP20050735A A HR P20050735AA HR P20050735 A HRP20050735 A HR P20050735A HR P20050735 B1 HRP20050735 B1 HR P20050735B1
Authority
HR
Croatia
Prior art keywords
dihydropteridinones
drugs
production
therefrom
groups
Prior art date
Application number
HRP20050735AA
Other languages
English (en)
Inventor
Matthias Hoffmann
Matthias Grauert
Trixi Brandl
Steffen Breitfelder
Christian Eickmeier
Martin Steegmaier
Gisela Schnapp
Anke Baum
Jens Jürgen QUANT
Flavio Solca
Florian Colbatzky
Original Assignee
Boehringer Ingelheim Pharma Gmbh & Co.Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma Gmbh & Co.Kg filed Critical Boehringer Ingelheim Pharma Gmbh & Co.Kg
Publication of HRP20050735A2 publication Critical patent/HRP20050735A2/xx
Publication of HRP20050735B1 publication Critical patent/HRP20050735B1/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Izum se odnosi na nove dihidropteridinone s općom formulom (I)pri čemu skupine L i R- Rimaju značenje dano u patentnim zahtjevima i specifikaciji, izomere otud, proces za pripravu tih dihidropteridinona i upotrebu otud kao farmaceutskih pripravaka.
HRP20050735AA 2003-02-26 2005-08-25 Dihidropteridinoni, metoda za njihovu proizvodnju i upotrebu u obliku lijekova HRP20050735B1 (hr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2003/001935 WO2004076454A1 (de) 2003-02-26 2003-02-26 Dihydropteridinone, verfahren zu deren herstellung und deren verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
HRP20050735A2 HRP20050735A2 (en) 2006-07-31
HRP20050735B1 true HRP20050735B1 (hr) 2013-08-31

Family

ID=32921552

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20050735AA HRP20050735B1 (hr) 2003-02-26 2005-08-25 Dihidropteridinoni, metoda za njihovu proizvodnju i upotrebu u obliku lijekova

Country Status (27)

Country Link
EP (1) EP1599478B1 (hr)
JP (1) JP3876265B2 (hr)
KR (1) KR100983462B1 (hr)
CN (2) CN100537570C (hr)
AT (1) ATE361924T1 (hr)
AU (1) AU2003215591B2 (hr)
BR (1) BR0318145A (hr)
CA (1) CA2517020C (hr)
CY (1) CY1106752T1 (hr)
DE (1) DE50307267D1 (hr)
DK (1) DK1599478T3 (hr)
EA (1) EA008778B1 (hr)
ES (1) ES2287583T3 (hr)
HK (1) HK1089444A1 (hr)
HR (1) HRP20050735B1 (hr)
IL (1) IL170419A (hr)
ME (1) ME00376B (hr)
MX (1) MXPA05009068A (hr)
NO (1) NO332538B1 (hr)
NZ (1) NZ542498A (hr)
PL (1) PL226417B1 (hr)
PT (1) PT1599478E (hr)
RS (1) RS52386B (hr)
SI (1) SI1599478T1 (hr)
TW (1) TWI313600B (hr)
UA (1) UA80743C2 (hr)
WO (1) WO2004076454A1 (hr)

Families Citing this family (112)

* Cited by examiner, † Cited by third party
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