HRP20040433A2 - Macrolides - Google Patents

Macrolides

Info

Publication number
HRP20040433A2
HRP20040433A2 HR20040433A HRP20040433A HRP20040433A2 HR P20040433 A2 HRP20040433 A2 HR P20040433A2 HR 20040433 A HR20040433 A HR 20040433A HR P20040433 A HRP20040433 A HR P20040433A HR P20040433 A2 HRP20040433 A2 HR P20040433A2
Authority
HR
Croatia
Prior art keywords
amino
dihydro
oxo
ethyl
cyclopropyl
Prior art date
Application number
HR20040433A
Other languages
English (en)
Croatian (hr)
Inventor
Alihod�i� Sulejman
Andreotti Daniele
Berdik Andrea
Bientinesi Ilaria
Biondi Stefano
Ciraco Manuela
Damiani Federica
Djerek Marko
Dumi� Miljenko
Erakovic Vesna
Hutinec Antun
Lazarevski Gorjana
Lociuro Sergio
Mar�i� Nata�a
Maru�i�-I�tuk Zorica
Mutak Stjepan
Paio Alfredo
Pavlovi� Dra�en
Quaglia Anna
Schoenfeld Wolfgang
Stimac Vlado
Tibasco Jessica
Original Assignee
Pliva-Istra�iva�ki institut d.o.o. Glaxo Group Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva-Istra�iva�ki institut d.o.o. Glaxo Group Limited filed Critical Pliva-Istra�iva�ki institut d.o.o. Glaxo Group Limited
Publication of HRP20040433A2 publication Critical patent/HRP20040433A2/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
HR20040433A 2001-11-14 2002-11-13 Macrolides HRP20040433A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0127349.9A GB0127349D0 (en) 2001-11-14 2001-11-14 Macrolides
PCT/GB2002/005101 WO2003042228A1 (en) 2001-11-14 2002-11-13 Macrolides

Publications (1)

Publication Number Publication Date
HRP20040433A2 true HRP20040433A2 (en) 2005-04-30

Family

ID=9925777

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20040433A HRP20040433A2 (en) 2001-11-14 2002-11-13 Macrolides

Country Status (20)

Country Link
US (1) US7202221B2 (enExample)
EP (1) EP1453846B1 (enExample)
JP (1) JP2005515978A (enExample)
CN (1) CN1307194C (enExample)
AR (1) AR037371A1 (enExample)
AT (1) ATE362479T1 (enExample)
BR (1) BR0214132A (enExample)
CA (1) CA2466975A1 (enExample)
DE (1) DE60220180T2 (enExample)
EA (1) EA007433B1 (enExample)
ES (1) ES2287332T3 (enExample)
GB (1) GB0127349D0 (enExample)
HR (1) HRP20040433A2 (enExample)
HU (1) HUP0402225A3 (enExample)
IL (1) IL161710A0 (enExample)
PL (1) PL371472A1 (enExample)
RS (1) RS41904A (enExample)
UA (1) UA77210C2 (enExample)
WO (1) WO2003042228A1 (enExample)
ZA (1) ZA200403684B (enExample)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6995143B2 (en) * 2002-02-28 2006-02-07 Basilea Pharmaceutica Ag Macrolides with antibacterial activity
US7022679B2 (en) 2002-05-13 2006-04-04 Enanta Pharmaceuticals, Inc. Processes for the preparation of 6-11 bicyclic erythromycin derivatives
US7135573B2 (en) 2002-05-13 2006-11-14 Enanta Pharmaceuticals, Inc. Processes for the preparation of O-(6-Pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine
US7910558B2 (en) 2002-05-13 2011-03-22 Enanta Pharmaceuticals, Inc. Bridged macrocyclic compounds and processes for the preparation thereof
US6764998B1 (en) 2003-06-18 2004-07-20 Enanta Pharmaceuticals, Inc. 6,11-4C-bicyclic 9a-azalide derivatives
JP4532263B2 (ja) * 2002-05-14 2010-08-25 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 置換されたキノロンカルボン酸、その誘導体、作用の部位、およびその使用
AR043050A1 (es) 2002-09-26 2005-07-13 Rib X Pharmaceuticals Inc Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos
GB0225384D0 (en) * 2002-10-31 2002-12-11 Glaxo Group Ltd Novel compounds
US6645941B1 (en) 2003-03-26 2003-11-11 Enanta Pharmaceuticals, Inc. 6,11-3C-bicyclic 9a-azalide derivatives
CL2004001012A1 (es) * 2003-05-13 2005-03-18 Glaxo Group Ltd Compuestos derivados de macrolidos de 14 o 15 miembros, sustituidos en posicion 4"; procedimiento para su preparacion; composicion farmaceutica que lo comprende; y su uso para el tratamiento o profilaxis de infecciones microbianas sistemicas o topica
GB0310986D0 (en) 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
GB0310980D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
GB0310979D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
GB0310984D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
US7276487B2 (en) 2003-09-23 2007-10-02 Enanta Pharmaceuticals, Inc. 9a, 11-3C-bicyclic 9a-azalide derivatives
WO2005070113A2 (en) 2004-01-09 2005-08-04 Enanta Pharmaceuticals, Inc. 9n-substituted 6-11 bicyclic erythromycin derivatives
EP1723159B1 (en) 2004-02-27 2019-06-12 Melinta Therapeutics, Inc. Macrocyclic compounds and methods of making and using the same
BRPI0510328A (pt) * 2004-05-06 2007-10-23 Glaxosmithkline Zagreb macrolìdeos ligados a éster úteis para o tratamento de infecções microbianas
EP1756134A1 (en) * 2004-05-06 2007-02-28 GlaxoSmithKline istrazivacki centar Zagreb d.o.o. Carbamate linked macrolides useful for the treatment of microbial infections
WO2006047167A2 (en) * 2004-10-21 2006-05-04 Janssen Pharmaceutica, N.V. 9 alkyl and 9 alkylidenyl 6-0 alkyl-11, 12 carbamate ketolide antimicrobials
GB0424951D0 (en) * 2004-11-11 2004-12-15 Glaxo Group Ltd Novel compounds
GB0424961D0 (en) * 2004-11-11 2004-12-15 Glaxo Group Ltd Novel compounds
GB0424958D0 (en) * 2004-11-11 2004-12-15 Glaxo Group Ltd Novel compounds
GB0424959D0 (en) * 2004-11-11 2004-12-15 Glaxo Group Ltd Novel compounds
KR101239490B1 (ko) * 2006-08-09 2013-03-05 바실리어 파마슈티카 아게 염증성 및 알러지성 질환에 유용한 새로운 마크로라이드
WO2008023248A2 (en) 2006-08-24 2008-02-28 Wockhardt Research Centre Novel macrolides and ketolides having antimicrobial activity
MX2010008750A (es) 2008-02-08 2010-08-31 Basilea Pharmaceutica Ag Nuevos macrolidos y su uso.
MX2011012614A (es) 2009-05-27 2012-02-22 Wockhardt Ltd Compuestos de quetolida que tienen actividad antimicrobiana.
RU2601550C2 (ru) 2010-12-09 2016-11-10 Вокхардт Лимитед Кетолидные соединения
BR112013019283A2 (pt) * 2011-01-31 2016-09-13 Meiji Seika Pharma Co Ltd composto, fármaco, composição farmacêutica e uso
JP5718488B2 (ja) 2011-03-01 2015-05-13 ウォックハート リミテッド ケトライド中間体の調製方法
CN119060110A (zh) * 2023-05-30 2024-12-03 北京理工大学 一种红霉素衍生物及其制备方法和应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0126344A2 (en) 1983-05-20 1984-11-28 Abbott Laboratories Tripeptide esters of therapeutic agents
US4742049A (en) * 1986-06-04 1988-05-03 Abbott Laboratories Semisynthetic erythromycin antibiotics
AU623764B2 (en) 1989-03-28 1992-05-21 Abbott Laboratories Erythromycin derivatives
CA2064634C (en) * 1991-04-04 1998-08-04 James V. Heck 9-deoxo-8a-aza-8a-homoerythromycin a derivatives modified at the 4"- and8a-positions
WO1997042206A1 (en) 1996-05-07 1997-11-13 Abbott Laboratories 6-o-substituted erythromycin compounds and method for making same
EP0895999A1 (en) * 1997-08-06 1999-02-10 Pfizer Products Inc. C-4" substituted macrolide antibiotics
US6262030B1 (en) * 1998-11-03 2001-07-17 Pfizer Inc. Erythromycin derivatives
OA11945A (en) 1999-05-24 2006-04-13 Pfizer Prod Inc 13-Methyl erythromycin derivatives.
AU6748500A (en) 1999-08-24 2001-03-19 Abbott Laboratories 9a-azalides with antibacterial activity
CA2398848C (en) 2000-02-24 2007-09-25 Abbott Laboratories Anti-infective agents useful against multidrug-resistant strains of bacteria
US6946446B2 (en) * 2000-02-24 2005-09-20 Abbott Laboratories Anti-infective agents useful against multidrug-resistant strains of bacteria
JP2002173498A (ja) 2000-09-27 2002-06-21 Hokuriku Seiyaku Co Ltd エリスロマイシン誘導体
GB0025688D0 (en) * 2000-10-19 2000-12-06 Glaxo Group Ltd Macrolides

Also Published As

Publication number Publication date
PL371472A1 (en) 2005-06-13
WO2003042228A1 (en) 2003-05-22
JP2005515978A (ja) 2005-06-02
ES2287332T3 (es) 2007-12-16
DE60220180D1 (de) 2007-06-28
DE60220180T2 (de) 2008-01-17
EP1453846B1 (en) 2007-05-16
EA007433B1 (ru) 2006-10-27
US7202221B2 (en) 2007-04-10
ATE362479T1 (de) 2007-06-15
CN1612888A (zh) 2005-05-04
AR037371A1 (es) 2004-11-03
CA2466975A1 (en) 2003-05-22
HUP0402225A3 (en) 2006-01-30
ZA200403684B (en) 2005-09-13
EA200400536A1 (ru) 2004-12-30
IL161710A0 (en) 2004-09-27
RS41904A (sr) 2006-10-27
HUP0402225A2 (hu) 2005-02-28
EP1453846A1 (en) 2004-09-08
GB0127349D0 (en) 2002-01-02
UA77210C2 (en) 2006-11-15
CN1307194C (zh) 2007-03-28
BR0214132A (pt) 2004-09-14
US20050080025A1 (en) 2005-04-14

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Year of fee payment: 7

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