HRP20040433A2 - Macrolides - Google Patents

Macrolides

Info

Publication number
HRP20040433A2
HRP20040433A2 HR20040433A HRP20040433A HRP20040433A2 HR P20040433 A2 HRP20040433 A2 HR P20040433A2 HR 20040433 A HR20040433 A HR 20040433A HR P20040433 A HRP20040433 A HR P20040433A HR P20040433 A2 HRP20040433 A2 HR P20040433A2
Authority
HR
Croatia
Prior art keywords
amino
dihydro
oxo
ethyl
cyclopropyl
Prior art date
Application number
HR20040433A
Other languages
English (en)
Croatian (hr)
Inventor
Alihod�i� Sulejman
Andreotti Daniele
Berdik Andrea
Bientinesi Ilaria
Biondi Stefano
Ciraco Manuela
Damiani Federica
Djerek Marko
Dumi� Miljenko
Erakovic Vesna
Hutinec Antun
Lazarevski Gorjana
Lociuro Sergio
Mar�i� Nata�a
Maru�i�-I�tuk Zorica
Mutak Stjepan
Paio Alfredo
Pavlovi� Dra�en
Quaglia Anna
Schoenfeld Wolfgang
Stimac Vlado
Tibasco Jessica
Original Assignee
Pliva-Istra�iva�ki institut d.o.o. Glaxo Group Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva-Istra�iva�ki institut d.o.o. Glaxo Group Limited filed Critical Pliva-Istra�iva�ki institut d.o.o. Glaxo Group Limited
Publication of HRP20040433A2 publication Critical patent/HRP20040433A2/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
HR20040433A 2001-11-14 2002-11-13 Macrolides HRP20040433A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0127349.9A GB0127349D0 (en) 2001-11-14 2001-11-14 Macrolides
PCT/GB2002/005101 WO2003042228A1 (en) 2001-11-14 2002-11-13 Macrolides

Publications (1)

Publication Number Publication Date
HRP20040433A2 true HRP20040433A2 (en) 2005-04-30

Family

ID=9925777

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20040433A HRP20040433A2 (en) 2001-11-14 2002-11-13 Macrolides

Country Status (20)

Country Link
US (1) US7202221B2 (enExample)
EP (1) EP1453846B1 (enExample)
JP (1) JP2005515978A (enExample)
CN (1) CN1307194C (enExample)
AR (1) AR037371A1 (enExample)
AT (1) ATE362479T1 (enExample)
BR (1) BR0214132A (enExample)
CA (1) CA2466975A1 (enExample)
DE (1) DE60220180T2 (enExample)
EA (1) EA007433B1 (enExample)
ES (1) ES2287332T3 (enExample)
GB (1) GB0127349D0 (enExample)
HR (1) HRP20040433A2 (enExample)
HU (1) HUP0402225A3 (enExample)
IL (1) IL161710A0 (enExample)
PL (1) PL371472A1 (enExample)
RS (1) RS41904A (enExample)
UA (1) UA77210C2 (enExample)
WO (1) WO2003042228A1 (enExample)
ZA (1) ZA200403684B (enExample)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6995143B2 (en) * 2002-02-28 2006-02-07 Basilea Pharmaceutica Ag Macrolides with antibacterial activity
US7022679B2 (en) 2002-05-13 2006-04-04 Enanta Pharmaceuticals, Inc. Processes for the preparation of 6-11 bicyclic erythromycin derivatives
US7910558B2 (en) 2002-05-13 2011-03-22 Enanta Pharmaceuticals, Inc. Bridged macrocyclic compounds and processes for the preparation thereof
US7135573B2 (en) 2002-05-13 2006-11-14 Enanta Pharmaceuticals, Inc. Processes for the preparation of O-(6-Pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine
US6764998B1 (en) 2003-06-18 2004-07-20 Enanta Pharmaceuticals, Inc. 6,11-4C-bicyclic 9a-azalide derivatives
EP1503759B1 (en) * 2002-05-14 2008-12-17 The Regents Of The University Of California Substituted quinolone carboxylic acids, their derivatives, site of action, and uses thereof
US7091196B2 (en) 2002-09-26 2006-08-15 Rib-X Pharmaceuticals, Inc. Bifunctional heterocyclic compounds and methods of making and using same
GB0225384D0 (en) * 2002-10-31 2002-12-11 Glaxo Group Ltd Novel compounds
US6645941B1 (en) 2003-03-26 2003-11-11 Enanta Pharmaceuticals, Inc. 6,11-3C-bicyclic 9a-azalide derivatives
EP1628989B1 (en) * 2003-05-13 2006-12-20 Glaxo Group Limited Novel 14 and 15 membered-ring compounds
GB0310979D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
GB0310984D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
GB0310980D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
GB0310986D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
US7276487B2 (en) 2003-09-23 2007-10-02 Enanta Pharmaceuticals, Inc. 9a, 11-3C-bicyclic 9a-azalide derivatives
US7265094B2 (en) 2004-01-09 2007-09-04 Enanta Pharmaceuticals, Inc. 9N-substituted 6-11 bicyclic erythromycin derivatives
EP2716647A3 (en) 2004-02-27 2014-08-20 Rib-X Pharmaceuticals, Inc. Macrocyclic compounds and methods of making and using the same
AU2005240849B2 (en) * 2004-05-06 2008-10-23 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. Ester linked macrolides useful for the treatment of microbial infections
CA2566112A1 (en) * 2004-05-06 2005-11-17 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O Carbamate linked macrolides useful for the treatment of microbial infections
WO2006047167A2 (en) * 2004-10-21 2006-05-04 Janssen Pharmaceutica, N.V. 9 alkyl and 9 alkylidenyl 6-0 alkyl-11, 12 carbamate ketolide antimicrobials
GB0424961D0 (en) * 2004-11-11 2004-12-15 Glaxo Group Ltd Novel compounds
GB0424958D0 (en) * 2004-11-11 2004-12-15 Glaxo Group Ltd Novel compounds
GB0424959D0 (en) 2004-11-11 2004-12-15 Glaxo Group Ltd Novel compounds
GB0424951D0 (en) * 2004-11-11 2004-12-15 Glaxo Group Ltd Novel compounds
ES2428874T3 (es) * 2006-08-09 2013-11-12 Basilea Pharmaceutica Ag Nuevos macrólidos útiles contra las enfermedades inflamatorias y alérgicas
CN101541331A (zh) 2006-08-24 2009-09-23 沃克哈特研究中心 具有抗微生物活性的新颖大环内酯和酮内酯
US8410065B2 (en) 2008-02-08 2013-04-02 Basilea Pharmaceutica Ag Macrolides and their use
EP2435460B1 (en) 2009-05-27 2015-01-07 Wockhardt Limited Ketolide compounds having antimicrobial activity
RU2601550C2 (ru) 2010-12-09 2016-11-10 Вокхардт Лимитед Кетолидные соединения
EP2671887A4 (en) * 2011-01-31 2014-06-25 Meiji Seika Pharma Co Ltd NEW MAKROLIDE DERIVATIVES
CN103619849B (zh) 2011-03-01 2016-05-25 沃克哈特有限公司 酮内酯中间体的制备方法
CN119060110A (zh) * 2023-05-30 2024-12-03 北京理工大学 一种红霉素衍生物及其制备方法和应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0126344A2 (en) 1983-05-20 1984-11-28 Abbott Laboratories Tripeptide esters of therapeutic agents
US4742049A (en) * 1986-06-04 1988-05-03 Abbott Laboratories Semisynthetic erythromycin antibiotics
IL93936A (en) * 1989-03-28 1994-06-24 Abbott Lab History of 9-dioxo-21,9-epoxy - erythromycin, method of preparation History of 11-oxo and 11-hydroxy, and pharmaceutical preparations containing them
CA2064634C (en) * 1991-04-04 1998-08-04 James V. Heck 9-deoxo-8a-aza-8a-homoerythromycin a derivatives modified at the 4"- and8a-positions
ES2252784T3 (es) 1996-05-07 2006-05-16 Abbott Laboratories Compuestos a base de eritromicina 6-0 sustituida y tecnica de produccion.
EP0895999A1 (en) * 1997-08-06 1999-02-10 Pfizer Products Inc. C-4" substituted macrolide antibiotics
US6262030B1 (en) * 1998-11-03 2001-07-17 Pfizer Inc. Erythromycin derivatives
EE200100613A (et) 1999-05-24 2003-02-17 Pfizer Products Inc. 13-metüülerütromütsiini derivaadid
CA2380455C (en) 1999-08-24 2009-06-02 Abbott Laboratories 9a-azalides with antibacterial activity
WO2001063539A2 (en) 2000-02-24 2001-08-30 Abbott Laboratories Anti-infective agents useful against multidrug-resistant strains of bacteria
US6946446B2 (en) * 2000-02-24 2005-09-20 Abbott Laboratories Anti-infective agents useful against multidrug-resistant strains of bacteria
JP2002173498A (ja) 2000-09-27 2002-06-21 Hokuriku Seiyaku Co Ltd エリスロマイシン誘導体
GB0025688D0 (en) 2000-10-19 2000-12-06 Glaxo Group Ltd Macrolides

Also Published As

Publication number Publication date
AR037371A1 (es) 2004-11-03
US7202221B2 (en) 2007-04-10
EA007433B1 (ru) 2006-10-27
ATE362479T1 (de) 2007-06-15
DE60220180D1 (de) 2007-06-28
HUP0402225A3 (en) 2006-01-30
GB0127349D0 (en) 2002-01-02
IL161710A0 (en) 2004-09-27
US20050080025A1 (en) 2005-04-14
CN1307194C (zh) 2007-03-28
WO2003042228A1 (en) 2003-05-22
ZA200403684B (en) 2005-09-13
EP1453846B1 (en) 2007-05-16
BR0214132A (pt) 2004-09-14
CA2466975A1 (en) 2003-05-22
EA200400536A1 (ru) 2004-12-30
PL371472A1 (en) 2005-06-13
UA77210C2 (en) 2006-11-15
HUP0402225A2 (hu) 2005-02-28
RS41904A (sr) 2006-10-27
JP2005515978A (ja) 2005-06-02
CN1612888A (zh) 2005-05-04
DE60220180T2 (de) 2008-01-17
ES2287332T3 (es) 2007-12-16
EP1453846A1 (en) 2004-09-08

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Legal Events

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Payment date: 20081111

Year of fee payment: 7

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