HRP20020181B1 - Farmaceutski pripravci koji sadrže derivat benzamida kao aktivan sastojak - Google Patents

Farmaceutski pripravci koji sadrže derivat benzamida kao aktivan sastojak

Info

Publication number
HRP20020181B1
HRP20020181B1 HRP20020181AA HRP20020181A HRP20020181B1 HR P20020181 B1 HRP20020181 B1 HR P20020181B1 HR P20020181A A HRP20020181A A HR P20020181AA HR P20020181 A HRP20020181 A HR P20020181A HR P20020181 B1 HRP20020181 B1 HR P20020181B1
Authority
HR
Croatia
Prior art keywords
benzamide derivative
active ingredient
pharmaceutical agent
formulations
mixing
Prior art date
Application number
HRP20020181AA
Other languages
English (en)
Inventor
Tsuneji Suzuki
Tomoyuki Ando
Masahiko Ishibashi
Masahiro Sakabe
Ikuo Sakai
Original Assignee
Bayer Intellectual Property Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Intellectual Property Gmbh filed Critical Bayer Intellectual Property Gmbh
Publication of HRP20020181A2 publication Critical patent/HRP20020181A2/xx
Publication of HRP20020181B1 publication Critical patent/HRP20020181B1/hr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Abstract

Stabilne farmaceutske formulacije mogu se dobiti miješanjem farmaceutski korisnog derivata benzamida ili njegove farmaceutski prihvatljive soli s aditivima koji ne daju lako produkte raspada, miješanjem soli organske kiseline, aminskog spoja i anorganske bazične supstancije, čime se dobivaju čvrste formulacije metodom suhog granuliranja, a zatim postavljanjem vrijednosti pH tekućih formulacija na vrijednost 4 do 12. Mogu se dobiti farmaceutske formulacije koje daju malo produkata raspada i koje su dovoljno stabilne da se koriste kao lijek.
HRP20020181AA 1999-08-16 2002-02-27 Farmaceutski pripravci koji sadrže derivat benzamida kao aktivan sastojak HRP20020181B1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP22955199A JP2001064177A (ja) 1999-08-16 1999-08-16 ベンズアミド誘導体を有効成分とする製剤
PCT/EP2000/008011 WO2001012193A1 (en) 1999-08-16 2000-08-16 Pharmaceutical agent comprising a benzamide derivative as active ingredient

Publications (2)

Publication Number Publication Date
HRP20020181A2 HRP20020181A2 (en) 2005-10-31
HRP20020181B1 true HRP20020181B1 (hr) 2016-01-29

Family

ID=16893948

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20020181AA HRP20020181B1 (hr) 1999-08-16 2002-02-27 Farmaceutski pripravci koji sadrže derivat benzamida kao aktivan sastojak

Country Status (29)

Country Link
EP (1) EP1207881B1 (hr)
JP (2) JP2001064177A (hr)
KR (1) KR100683876B1 (hr)
CN (1) CN1205931C (hr)
AR (1) AR031074A1 (hr)
AU (1) AU780151B2 (hr)
BG (1) BG65662B1 (hr)
BR (1) BR0013283A (hr)
CA (1) CA2380757C (hr)
CY (1) CY1116273T1 (hr)
CZ (1) CZ302924B6 (hr)
DK (1) DK1207881T3 (hr)
EE (1) EE05331B1 (hr)
ES (1) ES2536705T3 (hr)
HK (1) HK1046501B (hr)
HR (1) HRP20020181B1 (hr)
HU (1) HU230386B1 (hr)
IL (1) IL148169A0 (hr)
MX (1) MXPA02001575A (hr)
NO (1) NO328957B1 (hr)
NZ (1) NZ517356A (hr)
PL (1) PL201388B1 (hr)
PT (1) PT1207881E (hr)
RU (1) RU2257206C2 (hr)
SK (1) SK287547B6 (hr)
TW (1) TWI245630B (hr)
UA (1) UA73316C2 (hr)
WO (1) WO2001012193A1 (hr)
ZA (1) ZA200201466B (hr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001081031A (ja) * 1999-08-30 2001-03-27 Schering Ag 溶解性および経口吸収性を改善したベンズアミド誘導体含有製剤
AU2001288102A1 (en) * 2000-09-22 2002-04-02 Takeda Chemical Industries Ltd. Solid preparations
IL163875A0 (en) 2002-03-07 2005-12-18 Univ Delaware Methods, compositions, and kits for enhancing oli gonucleotide mediated nucleic acid sequence alteration using compositions comprising a histone de
GB0316206D0 (en) 2003-07-10 2003-08-13 Glaxo Group Ltd Pharmaceutical formulation
KR20090125209A (ko) 2007-03-28 2009-12-03 산텐 세이야꾸 가부시키가이샤 히스톤 탈아세틸화 효소 저해 작용을 갖는 화합물을 유효 성분으로서 함유하는 안압 하강제
KR101405615B1 (ko) * 2007-08-27 2014-06-12 (주)아모레퍼시픽 조성물 내 ｐＨ 조절을 통해 안정화된 벤즈아미드 화합물을함유하는 피부 외용제 조성물, 및 그 벤즈아미드 화합물안정화 방법
GB2462893B (en) * 2008-08-29 2010-10-13 Bayer Schering Pharma Ag N-(2-aminophenyl)-4-[N-(pyridine-3-yl)-methoxycarbonyl-aminomethyl]-benzamide (MS-275) polymorph B
PE20110677A1 (es) * 2008-08-29 2011-09-16 Bayer Ip Gmbh Polimorfo b de la n-(2-aminofenil)-4-[n-(piridin-3-il) metoxicarbonilamino-metil]benzamida (ms-275)
KR102142257B1 (ko) * 2013-04-04 2020-08-07 다이이찌 산쿄 가부시키가이샤 아미노카르복실산의 염의 고형 조성물
WO2016148264A1 (ja) 2015-03-19 2016-09-22 第一三共株式会社 着色剤を含有する固形製剤
JP6630343B2 (ja) 2015-03-19 2020-01-15 第一三共株式会社 抗酸化剤を含有する固形製剤
WO2020153520A1 (ko) * 2019-01-25 2020-07-30 (주)아모레퍼시픽 벤조산아마이드 화합물 및 용해보조제를 포함하는 조성물

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0847992A1 (en) * 1996-09-30 1998-06-17 Mitsui Chemicals, Inc. Benzamide derivatives, useful as cell differentiation inducers

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3354090B2 (ja) * 1996-09-30 2002-12-09 シエーリング アクチエンゲゼルシャフト 分化誘導剤

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0847992A1 (en) * 1996-09-30 1998-06-17 Mitsui Chemicals, Inc. Benzamide derivatives, useful as cell differentiation inducers

Also Published As

Publication number Publication date
ZA200201466B (en) 2002-09-02
BG106516A (en) 2002-10-31
HU230386B1 (hu) 2016-03-29
NZ517356A (en) 2003-07-25
AU780151B2 (en) 2005-03-03
NO328957B1 (no) 2010-06-28
SK287547B6 (sk) 2011-01-04
JP2001064177A (ja) 2001-03-13
JP4854158B2 (ja) 2012-01-18
KR20020020815A (ko) 2002-03-15
HUP0203226A2 (hu) 2003-01-28
IL148169A0 (en) 2002-09-12
DK1207881T3 (da) 2015-06-22
CN1205931C (zh) 2005-06-15
AR031074A1 (es) 2003-09-10
BG65662B1 (bg) 2009-05-29
EE200200073A (et) 2003-04-15
KR100683876B1 (ko) 2007-02-15
UA73316C2 (uk) 2005-07-15
NO20020774L (no) 2002-03-04
MXPA02001575A (es) 2003-10-14
CZ2002540A3 (cs) 2002-06-12
BR0013283A (pt) 2002-04-23
NO20020774D0 (no) 2002-02-15
EP1207881B1 (en) 2015-04-01
RU2257206C2 (ru) 2005-07-27
RU2002106815A (ru) 2004-01-27
TWI245630B (en) 2005-12-21
WO2001012193A1 (en) 2001-02-22
PT1207881E (pt) 2015-06-05
CN1370068A (zh) 2002-09-18
CZ302924B6 (cs) 2012-01-18
JP2003507330A (ja) 2003-02-25
CY1116273T1 (el) 2017-02-08
PL353449A1 (en) 2003-11-17
EE05331B1 (et) 2010-08-16
HRP20020181A2 (en) 2005-10-31
CA2380757A1 (en) 2001-02-22
AU6442700A (en) 2001-03-13
SK2092002A3 (en) 2002-07-02
ES2536705T3 (es) 2015-05-27
EP1207881A1 (en) 2002-05-29
HUP0203226A3 (en) 2003-12-29
PL201388B1 (pl) 2009-04-30
HK1046501B (zh) 2005-09-30
HK1046501A1 (en) 2003-01-17
CA2380757C (en) 2009-01-27

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Legal Events

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AIPI Request for the grant of a patent on the basis of a substantive examination of a patent application
A1OB Publication of a patent application
PNAN Change of the applicant name, address/residence

Owner name: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT, DE

PNAN Change of the applicant name, address/residence

Owner name: BAYER PHARMA AKTIENGESELLSCHAFT, DE

PPPP Transfer of rights

Owner name: BAYER INTELLECTUAL PROPERTY GMBH, DE

B1PR Patent granted
ODRP Renewal fee for the maintenance of a patent

Payment date: 20190725

Year of fee payment: 20

PB20 Patent expired after termination of 20 years

Effective date: 20200816