CY1116273T1 - Φαρμακευτικος παραγοντας που περιλαμβανει ενα παραγωγο βενζαμιδιου ως ενεργο συστατικο - Google Patents
Φαρμακευτικος παραγοντας που περιλαμβανει ενα παραγωγο βενζαμιδιου ως ενεργο συστατικοInfo
- Publication number
- CY1116273T1 CY1116273T1 CY20151100423T CY151100423T CY1116273T1 CY 1116273 T1 CY1116273 T1 CY 1116273T1 CY 20151100423 T CY20151100423 T CY 20151100423T CY 151100423 T CY151100423 T CY 151100423T CY 1116273 T1 CY1116273 T1 CY 1116273T1
- Authority
- CY
- Cyprus
- Prior art keywords
- active ingredient
- factor including
- mixing
- pharmaceutical
- degradation products
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Cardiology (AREA)
- Transplantation (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Σταθερά φαρμακευτικά σκευάσματα μπορούν να ληφθούν αναμιγνύοντας ένα φαρμακευτικώς χρήσιμο παράγωγο βενζαμιδίου ή ένα φαρμακευτικώς αποδεκτό άλας αυτού με πρόσθετα που δεν παράγουν εύκολα προϊόντα αποδόμησης, συμμιγνύοντας ένα άλας οργανικού οξέος, μια ένωση αμίνης, και μια ανόργανη βασική ουσία, παράγοντας στερεά σκευάσματα με τη μέθοδο ξηρής κοκκοποίησης, και περαιτέρω ρυθμίζοντας το pΗ των υγρών σκευασμάτων στο 4 έως 12. Μπορούν να ληφθούν φαρμακευτικά σκευάσματα που παράγουν ελάχιστα προϊόντα αποδόμησης και που είναι αρκετά σταθερά για να χρησιμοποιηθούν ως ιατρικά φάρμακα.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP22955199A JP2001064177A (ja) | 1999-08-16 | 1999-08-16 | ベンズアミド誘導体を有効成分とする製剤 |
EP00951523.0A EP1207881B1 (en) | 1999-08-16 | 2000-08-16 | Pharmaceutical agent comprising a benzamide derivative as active ingredient |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1116273T1 true CY1116273T1 (el) | 2017-02-08 |
Family
ID=16893948
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20151100423T CY1116273T1 (el) | 1999-08-16 | 2015-05-13 | Φαρμακευτικος παραγοντας που περιλαμβανει ενα παραγωγο βενζαμιδιου ως ενεργο συστατικο |
Country Status (29)
Country | Link |
---|---|
EP (1) | EP1207881B1 (el) |
JP (2) | JP2001064177A (el) |
KR (1) | KR100683876B1 (el) |
CN (1) | CN1205931C (el) |
AR (1) | AR031074A1 (el) |
AU (1) | AU780151B2 (el) |
BG (1) | BG65662B1 (el) |
BR (1) | BR0013283A (el) |
CA (1) | CA2380757C (el) |
CY (1) | CY1116273T1 (el) |
CZ (1) | CZ302924B6 (el) |
DK (1) | DK1207881T3 (el) |
EE (1) | EE05331B1 (el) |
ES (1) | ES2536705T3 (el) |
HK (1) | HK1046501B (el) |
HR (1) | HRP20020181B1 (el) |
HU (1) | HU230386B1 (el) |
IL (1) | IL148169A0 (el) |
MX (1) | MXPA02001575A (el) |
NO (1) | NO328957B1 (el) |
NZ (1) | NZ517356A (el) |
PL (1) | PL201388B1 (el) |
PT (1) | PT1207881E (el) |
RU (1) | RU2257206C2 (el) |
SK (1) | SK287547B6 (el) |
TW (1) | TWI245630B (el) |
UA (1) | UA73316C2 (el) |
WO (1) | WO2001012193A1 (el) |
ZA (1) | ZA200201466B (el) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001081031A (ja) * | 1999-08-30 | 2001-03-27 | Schering Ag | 溶解性および経口吸収性を改善したベンズアミド誘導体含有製剤 |
AU2001288102A1 (en) * | 2000-09-22 | 2002-04-02 | Takeda Chemical Industries Ltd. | Solid preparations |
IL163875A0 (en) | 2002-03-07 | 2005-12-18 | Univ Delaware | Methods, compositions, and kits for enhancing oli gonucleotide mediated nucleic acid sequence alteration using compositions comprising a histone de |
GB0316206D0 (en) | 2003-07-10 | 2003-08-13 | Glaxo Group Ltd | Pharmaceutical formulation |
US20100056522A1 (en) | 2007-03-28 | 2010-03-04 | Santen Pharmaceutical Co., Ltd. | Intraocular pressure-lowering agent comprising compound having histone deacetylase inhibitor effect as active ingredient |
KR101405615B1 (ko) * | 2007-08-27 | 2014-06-12 | (주)아모레퍼시픽 | 조성물 내 pH 조절을 통해 안정화된 벤즈아미드 화합물을함유하는 피부 외용제 조성물, 및 그 벤즈아미드 화합물안정화 방법 |
GB2462893B (en) * | 2008-08-29 | 2010-10-13 | Bayer Schering Pharma Ag | N-(2-aminophenyl)-4-[N-(pyridine-3-yl)-methoxycarbonyl-aminomethyl]-benzamide (MS-275) polymorph B |
DK2350005T3 (da) * | 2008-08-29 | 2012-03-19 | Bayer Pharma AG | N-(2-aminophenyl)-4-[N-(pyridin-3-yl)-methoxy-carbonyl-aminomehtyl]benzamid(MS-275)-polymorf B |
BR112014029538B1 (pt) * | 2013-04-04 | 2022-07-05 | Daiichi Sankyo Company, Limited | Composição farmacêutica sólida |
WO2016148263A1 (ja) | 2015-03-19 | 2016-09-22 | 第一三共株式会社 | 抗酸化剤を含有する固形製剤 |
CA2980097C (en) | 2015-03-19 | 2019-10-29 | Daiichi Sankyo Company, Limited | Solid preparation containing colorant |
US12083226B2 (en) | 2018-07-30 | 2024-09-10 | Daiichi Sankyo Company, Limited | Stabilizer-containing solid drug formulation |
CN111867559A (zh) * | 2019-01-25 | 2020-10-30 | 株式会社爱茉莉太平洋 | 含有苯甲酰胺化合物以及增溶剂的组合物 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3354090B2 (ja) * | 1996-09-30 | 2002-12-09 | シエーリング アクチエンゲゼルシャフト | 分化誘導剤 |
US6174905B1 (en) * | 1996-09-30 | 2001-01-16 | Mitsui Chemicals, Inc. | Cell differentiation inducer |
-
1999
- 1999-08-16 JP JP22955199A patent/JP2001064177A/ja active Pending
-
2000
- 2000-08-07 TW TW089115860A patent/TWI245630B/zh not_active IP Right Cessation
- 2000-08-15 AR ARP000104212A patent/AR031074A1/es active IP Right Grant
- 2000-08-16 EE EEP200200073A patent/EE05331B1/xx unknown
- 2000-08-16 HU HU0203226A patent/HU230386B1/hu unknown
- 2000-08-16 RU RU2002106815/15A patent/RU2257206C2/ru active
- 2000-08-16 KR KR1020027002002A patent/KR100683876B1/ko active IP Right Grant
- 2000-08-16 BR BR0013283-7A patent/BR0013283A/pt not_active Application Discontinuation
- 2000-08-16 MX MXPA02001575A patent/MXPA02001575A/es active IP Right Grant
- 2000-08-16 WO PCT/EP2000/008011 patent/WO2001012193A1/en active IP Right Grant
- 2000-08-16 CA CA002380757A patent/CA2380757C/en not_active Expired - Lifetime
- 2000-08-16 DK DK00951523.0T patent/DK1207881T3/da active
- 2000-08-16 PL PL353449A patent/PL201388B1/pl unknown
- 2000-08-16 SK SK209-2002A patent/SK287547B6/sk not_active IP Right Cessation
- 2000-08-16 CN CNB008117187A patent/CN1205931C/zh not_active Expired - Lifetime
- 2000-08-16 EP EP00951523.0A patent/EP1207881B1/en not_active Expired - Lifetime
- 2000-08-16 PT PT951523T patent/PT1207881E/pt unknown
- 2000-08-16 JP JP2001516539A patent/JP4854158B2/ja not_active Expired - Lifetime
- 2000-08-16 AU AU64427/00A patent/AU780151B2/en not_active Expired
- 2000-08-16 ES ES00951523.0T patent/ES2536705T3/es not_active Expired - Lifetime
- 2000-08-16 CZ CZ20020540A patent/CZ302924B6/cs not_active IP Right Cessation
- 2000-08-16 IL IL14816900A patent/IL148169A0/xx active IP Right Grant
- 2000-08-16 UA UA2002032040A patent/UA73316C2/uk unknown
- 2000-08-16 NZ NZ517356A patent/NZ517356A/en not_active IP Right Cessation
-
2002
- 2002-02-15 NO NO20020774A patent/NO328957B1/no not_active IP Right Cessation
- 2002-02-21 ZA ZA200201466A patent/ZA200201466B/en unknown
- 2002-02-27 HR HRP20020181AA patent/HRP20020181B1/hr not_active IP Right Cessation
- 2002-03-14 BG BG106516A patent/BG65662B1/bg unknown
- 2002-10-22 HK HK02107641.6A patent/HK1046501B/zh not_active IP Right Cessation
-
2015
- 2015-05-13 CY CY20151100423T patent/CY1116273T1/el unknown
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