BR0013283A - Agente farmacêutico que compreende um derivado de benzamida como ingrediente ativo - Google Patents

Agente farmacêutico que compreende um derivado de benzamida como ingrediente ativo

Info

Publication number
BR0013283A
BR0013283A BR0013283-7A BR0013283A BR0013283A BR 0013283 A BR0013283 A BR 0013283A BR 0013283 A BR0013283 A BR 0013283A BR 0013283 A BR0013283 A BR 0013283A
Authority
BR
Brazil
Prior art keywords
benzamide derivative
active ingredient
pharmaceutical agent
formulations
degradation products
Prior art date
Application number
BR0013283-7A
Other languages
English (en)
Inventor
Tsuneji Suzuki
Tomoyuki Ando
Masahiko Ishibashi
Masahiro Sakabe
Ikuo Sakai
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of BR0013283A publication Critical patent/BR0013283A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Communicable Diseases (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Patente de Invenção: "AGENTE FARMACêUTICO QUE COMPREENDE UM DERIVADO DE BENZAMIDA COMO INGREDIENTE ATIVO". Esta invenção refere-se a formulações farmacêuticas estáveis que podem ser obtidas misturando um derivado de benzamida farmaceuticamente útil ou um sal do mesmo farmaceuticamente aceitável com aditivos que não produzem facilmente produtos de degradação, combinando um sal de ácido orgânico, um composto de amina e uma substância básica inorgânica, produzindo formulações sólidas pelo método de granulação seca e adicionalmente ajustando o pH das formulações líquidas em 4 a 12. Formulações farmacêuticas que produzem poucos produtos de degradação e que são suficientemente estáveis para ser usadas como drogas médicas podem ser obtidas
BR0013283-7A 1999-08-16 2000-08-16 Agente farmacêutico que compreende um derivado de benzamida como ingrediente ativo BR0013283A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP22955199A JP2001064177A (ja) 1999-08-16 1999-08-16 ベンズアミド誘導体を有効成分とする製剤
PCT/EP2000/008011 WO2001012193A1 (en) 1999-08-16 2000-08-16 Pharmaceutical agent comprising a benzamide derivative as active ingredient

Publications (1)

Publication Number Publication Date
BR0013283A true BR0013283A (pt) 2002-04-23

Family

ID=16893948

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0013283-7A BR0013283A (pt) 1999-08-16 2000-08-16 Agente farmacêutico que compreende um derivado de benzamida como ingrediente ativo

Country Status (29)

Country Link
EP (1) EP1207881B1 (pt)
JP (2) JP2001064177A (pt)
KR (1) KR100683876B1 (pt)
CN (1) CN1205931C (pt)
AR (1) AR031074A1 (pt)
AU (1) AU780151B2 (pt)
BG (1) BG65662B1 (pt)
BR (1) BR0013283A (pt)
CA (1) CA2380757C (pt)
CY (1) CY1116273T1 (pt)
CZ (1) CZ302924B6 (pt)
DK (1) DK1207881T3 (pt)
EE (1) EE05331B1 (pt)
ES (1) ES2536705T3 (pt)
HK (1) HK1046501B (pt)
HR (1) HRP20020181B1 (pt)
HU (1) HU230386B1 (pt)
IL (1) IL148169A0 (pt)
MX (1) MXPA02001575A (pt)
NO (1) NO328957B1 (pt)
NZ (1) NZ517356A (pt)
PL (1) PL201388B1 (pt)
PT (1) PT1207881E (pt)
RU (1) RU2257206C2 (pt)
SK (1) SK287547B6 (pt)
TW (1) TWI245630B (pt)
UA (1) UA73316C2 (pt)
WO (1) WO2001012193A1 (pt)
ZA (1) ZA200201466B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001081031A (ja) * 1999-08-30 2001-03-27 Schering Ag 溶解性および経口吸収性を改善したベンズアミド誘導体含有製剤
CA2423329A1 (en) * 2000-09-22 2003-03-20 Takeda Chemical Industries, Ltd. Solid preparations
WO2003075856A2 (en) 2002-03-07 2003-09-18 University Of Delaware Methods, compositions, and kits for enhancing oligonucleotide-mediated nucleic acid sequence alteration using compositions comprising a histone deacetylase inhibitor, lambda phage beta protein, or hydroxyurea
GB0316206D0 (en) 2003-07-10 2003-08-13 Glaxo Group Ltd Pharmaceutical formulation
WO2008123395A1 (ja) 2007-03-28 2008-10-16 Santen Pharmaceutical Co., Ltd. ヒストン脱アセチル化酵素阻害作用を有する化合物を有効成分として含有する眼圧下降剤
KR101405615B1 (ko) * 2007-08-27 2014-06-12 (주)아모레퍼시픽 조성물 내 ｐＨ 조절을 통해 안정화된 벤즈아미드 화합물을함유하는 피부 외용제 조성물, 및 그 벤즈아미드 화합물안정화 방법
PT2350005E (pt) * 2008-08-29 2012-03-12 Bayer Pharma AG Polimorfo b de n-(2-aminofenil)-4-[n-(piridina-3-il)¿ metoxicarbonil-aminometil]-benzamida (ms-275)
GB2462893B (en) * 2008-08-29 2010-10-13 Bayer Schering Pharma Ag N-(2-aminophenyl)-4-[N-(pyridine-3-yl)-methoxycarbonyl-aminomethyl]-benzamide (MS-275) polymorph B
CN104334169B (zh) * 2013-04-04 2016-11-02 第一三共株式会社 包含氨基羧酸盐的固体组合物
US10561628B2 (en) 2015-03-19 2020-02-18 Daiichi Sankyo Company, Limited Solid preparation including antioxidant
BR112017019920B1 (pt) 2015-03-19 2023-11-07 Daiichi Sankyo Company, Limited Preparação sólida farmacêutica, e, método para estabilização de uma preparação sólida farmacêutica
TWI845532B (zh) 2018-07-30 2024-06-21 日商第一三共股份有限公司 含安定劑之醫藥品的固體製劑
CN111867559A (zh) * 2019-01-25 2020-10-30 株式会社爱茉莉太平洋 含有苯甲酰胺化合物以及增溶剂的组合物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3354090B2 (ja) * 1996-09-30 2002-12-09 シエーリング アクチエンゲゼルシャフト 分化誘導剤
US6174905B1 (en) * 1996-09-30 2001-01-16 Mitsui Chemicals, Inc. Cell differentiation inducer

Also Published As

Publication number Publication date
BG106516A (en) 2002-10-31
PT1207881E (pt) 2015-06-05
CY1116273T1 (el) 2017-02-08
NO20020774D0 (no) 2002-02-15
CZ302924B6 (cs) 2012-01-18
PL353449A1 (en) 2003-11-17
DK1207881T3 (da) 2015-06-22
IL148169A0 (en) 2002-09-12
NO20020774L (no) 2002-03-04
AU6442700A (en) 2001-03-13
HUP0203226A3 (en) 2003-12-29
CN1205931C (zh) 2005-06-15
AU780151B2 (en) 2005-03-03
TWI245630B (en) 2005-12-21
WO2001012193A1 (en) 2001-02-22
BG65662B1 (bg) 2009-05-29
NZ517356A (en) 2003-07-25
ZA200201466B (en) 2002-09-02
KR100683876B1 (ko) 2007-02-15
JP2001064177A (ja) 2001-03-13
CA2380757A1 (en) 2001-02-22
JP4854158B2 (ja) 2012-01-18
MXPA02001575A (es) 2003-10-14
EE200200073A (et) 2003-04-15
AR031074A1 (es) 2003-09-10
HK1046501B (zh) 2005-09-30
RU2002106815A (ru) 2004-01-27
KR20020020815A (ko) 2002-03-15
ES2536705T3 (es) 2015-05-27
SK2092002A3 (en) 2002-07-02
EP1207881B1 (en) 2015-04-01
EP1207881A1 (en) 2002-05-29
CN1370068A (zh) 2002-09-18
HRP20020181B1 (hr) 2016-01-29
CZ2002540A3 (cs) 2002-06-12
HRP20020181A2 (en) 2005-10-31
SK287547B6 (sk) 2011-01-04
HK1046501A1 (en) 2003-01-17
RU2257206C2 (ru) 2005-07-27
HUP0203226A2 (hu) 2003-01-28
UA73316C2 (uk) 2005-07-15
HU230386B1 (hu) 2016-03-29
PL201388B1 (pl) 2009-04-30
CA2380757C (en) 2009-01-27
NO328957B1 (no) 2010-06-28
JP2003507330A (ja) 2003-02-25
EE05331B1 (et) 2010-08-16

Similar Documents

Publication Publication Date Title
BR0008590A (pt) Agente de entrega polimérico, composição, formade unidade de dosagem, método para administrarum agente biologicamente ativo a um animalnecessitando o agente, método para preparar umacomposição; e composto
CY1116273T1 (el) Φαρμακευτικος παραγοντας που περιλαμβανει ενα παραγωγο βενζαμιδιου ως ενεργο συστατικο
AR037490A1 (es) Composiciones farmaceuticas solidas, proceso para su preparacion, kit para el tratamiento de la obesidad y uso de dichas composiciones en la elaboracion de medicamentos
BR0212468A (pt) Compoto de uréia ativos como antagonistas de receptor de vanilóides para o tratamento de dor
ES2063146T3 (es) Composiciones farmaceuticas que contienen acido n-(3,4-dimetoxicinamoil)-antranilico.
DK1660037T3 (da) Aripiprazol-injektionssuspension
GT199700095A (es) Derivados 6,5-heterobiciclicos sustituidos.
PT97689A (pt) Processo para a preparacao de composicoes farmaceuticas incorporando como ingrediente activo isoxazol-4-carboxilamida e hidroxialquilideno-cianoacetamida
BRPI0416752A (pt) composição farmacêutica, uso de um ou mais compostos, método para a prevenção ou tratamento de distúrbios, compostos, e, processo para a preparação de uma composição farmacêutica
DE60134245D1 (de) (5-(2-hydroxy-4-chlorbenzoyl)valeriansäure und deren salze, und zusammensetzungen zur zuführung von wirkstoffen, die diese verbindungen enthalten
BR9608435A (pt) Metodo para medicação do sistema de controle inflatório e de reações inflamatórias adversas e para produção de composto para o tratamento da patologia de reações inflamatórias adversas.
DE59902270D1 (de) Feuchtigkeitsaktivierbares therapeutisches system
BR9916575A (pt) Composição farmacêutica de liberação controlada com mesilato de tilidina como substância-ativa
ATE420638T1 (de) Stabile feste medizinische zusammensetzung für die orale verabreichung von ramosetron
AR018607A1 (es) Preparacion farmaceutica que en calidad de ingrediente activo contiene levotiroxina sodica, y un procedimiento para su preparacion
ATE440838T1 (de) Pharmazeutisch aktive sulfonylaminosäurederivate
BR0010983A (pt) Preparações para a aplicação de agentes antiinflamatórios
BR9915729A (pt) Amidas Èmega de n-arilsulfonil-aminoácido
AR016382A1 (es) Uso de un derivado del acido bencil-indazol metoxialcanoico.
HUP9801712A2 (hu) Racemizálás ellen stabilizált, cilansetrontartalmú gyógyászati készítmények, előállításuk és a stabilizáló adalékanyagok alkalmazása
BR0011845A (pt) Complexo farmacêutico
DE60217292D1 (de) Veterinärmedizinische dermatologische zusammensetzung
PT97164A (pt) Processo para a estabilizacao de uma preparacao que contenham o composto 4-etil-2-hidroxi-imino-5-nitro-3-hexenamida e de composicoes farmaceuticas que o contenham
GEP20053581B (en) Pharmaceutical Composition and Method for Preparation Thereof
TR200003451T2 (tr) Pirimidin-Aminometil-Piridin Türevleri, Hazırlanmaları ve helikobakter bakterinin kontrolünde kullanımları

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 13, 24 E 25 DA LPI.

B12B Appeal against refusal [chapter 12.2 patent gazette]
B25D Requested change of name of applicant approved

Owner name: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE)

Free format text: NOME ALTERADO DE: SCHERING AKTIENGESELLSCHAFT