DE60203997D1 - Nasses granulationsverfahren zur herstellung von pharmazeutischen tabletten mit paroxetinhydrochlorid anhydrat - Google Patents
Nasses granulationsverfahren zur herstellung von pharmazeutischen tabletten mit paroxetinhydrochlorid anhydratInfo
- Publication number
- DE60203997D1 DE60203997D1 DE60203997T DE60203997T DE60203997D1 DE 60203997 D1 DE60203997 D1 DE 60203997D1 DE 60203997 T DE60203997 T DE 60203997T DE 60203997 T DE60203997 T DE 60203997T DE 60203997 D1 DE60203997 D1 DE 60203997D1
- Authority
- DE
- Germany
- Prior art keywords
- paroxetine hydrochloride
- wet granulation
- preparation
- pharmaceutical tablets
- hydrochloride anhydrate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- AHOUBRCZNHFOSL-UHFFFAOYSA-N 3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine Chemical compound C1=CC(F)=CC=C1C1C(COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-UHFFFAOYSA-N 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 229960005183 paroxetine hydrochloride Drugs 0.000 title abstract 2
- 238000005550 wet granulation Methods 0.000 title abstract 2
- 239000008187 granular material Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000002671 adjuvant Substances 0.000 abstract 1
- 238000005469 granulation Methods 0.000 abstract 1
- 230000003179 granulation Effects 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK200100341 | 2001-03-02 | ||
| DK200100341A DK200100341A (da) | 2001-03-02 | 2001-03-02 | Fremgangsmåde til fremstilling af farmaceutiske tabletter indeholdende paroxetinhydrochlorid-anhydrat |
| PCT/DK2002/000134 WO2002069969A1 (en) | 2001-03-02 | 2002-03-01 | A process for the manufacture of pharmaceutical tablets containing paroxetine hydrochloride anhydrate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60203997D1 true DE60203997D1 (de) | 2005-06-09 |
| DE60203997T2 DE60203997T2 (de) | 2006-02-23 |
Family
ID=8160333
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60203997T Expired - Fee Related DE60203997T2 (de) | 2001-03-02 | 2002-03-01 | Nasses granulationsverfahren zur herstellung von pharmazeutischen tabletten mit paroxetinhydrochlorid anhydrat |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20040072912A1 (de) |
| EP (1) | EP1363633B1 (de) |
| AT (1) | ATE294580T1 (de) |
| AU (1) | AU2002233182B2 (de) |
| CA (1) | CA2439460A1 (de) |
| DE (1) | DE60203997T2 (de) |
| DK (2) | DK200100341A (de) |
| ES (1) | ES2239707T3 (de) |
| NO (1) | NO20033855D0 (de) |
| PT (1) | PT1363633E (de) |
| WO (1) | WO2002069969A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2470496A1 (en) | 2001-12-28 | 2003-07-17 | Teva Pharmaceutical Industries Ltd. | A stable pharmaceutical formulation of paroxetine hydrochloride and a process for preparation thereof |
| US20040208932A1 (en) * | 2003-04-17 | 2004-10-21 | Ramachandran Thembalath | Stabilized paroxetine hydrochloride formulation |
| EP1675574A2 (de) * | 2003-10-08 | 2006-07-05 | Ranbaxy Laboratories, Ltd. | Pharmazeutische zusammensetzungen von paroxetin mit mikrokristalliner cellulose, hergestellt durch nassgranulation |
| EP1841730A4 (de) * | 2005-01-19 | 2010-10-27 | Merck Frosst Canada Ltd | Cathepsin-k-inhibitoren und atherosklerose |
| JP5153629B2 (ja) * | 2005-08-02 | 2013-02-27 | ルピン・リミテッド | 選択的セロトニン再取り込み阻害剤の新規の制御放出組成物 |
| CN113350350A (zh) * | 2020-03-07 | 2021-09-07 | 齐鲁制药有限公司 | 一种含有盐酸培唑帕尼的药物组合物的制备方法 |
| CN113730369B (zh) * | 2020-05-27 | 2023-07-14 | 石药集团欧意药业有限公司 | 一种阿哌沙班片剂组合物及其制备方法 |
| WO2024088560A1 (en) * | 2022-10-28 | 2024-05-02 | Roquette Freres | Compound for formulating moisture sensitive active ingredients |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0149266B1 (de) * | 1983-12-19 | 1988-05-18 | Duphar International Research B.V | Verfahren zum Trocknen von festen Stoffen und Vorrichtung zu dessen Ausführung |
| US5856493A (en) * | 1995-02-06 | 1999-01-05 | Smithkline Beecham Corporation | Process for making novel form of paroxeting hydrochloride anhydrate |
| GB9806312D0 (en) * | 1998-03-24 | 1998-05-20 | Smithkline Beecham Plc | Novel formulations |
| GB9914600D0 (en) * | 1999-06-22 | 1999-08-25 | Smithkline Beecham Plc | Novel,process |
| GB0003232D0 (en) * | 2000-02-11 | 2000-04-05 | Smithkline Beecham Plc | Novel composition |
| US6660298B1 (en) * | 2000-07-27 | 2003-12-09 | Pentech Pharmaceuticals, Inc. | Paroxetine tablets and capsules |
| AU2001296084A1 (en) * | 2000-08-28 | 2002-03-13 | Synthon B.V. | Paroxetine compositions and processes for making the same |
-
2001
- 2001-03-02 DK DK200100341A patent/DK200100341A/da not_active Application Discontinuation
-
2002
- 2002-03-01 CA CA002439460A patent/CA2439460A1/en not_active Abandoned
- 2002-03-01 EP EP02700190A patent/EP1363633B1/de not_active Expired - Lifetime
- 2002-03-01 PT PT02700190T patent/PT1363633E/pt unknown
- 2002-03-01 AU AU2002233182A patent/AU2002233182B2/en not_active Ceased
- 2002-03-01 AT AT02700190T patent/ATE294580T1/de not_active IP Right Cessation
- 2002-03-01 US US10/469,031 patent/US20040072912A1/en not_active Abandoned
- 2002-03-01 DK DK02700190T patent/DK1363633T3/da active
- 2002-03-01 ES ES02700190T patent/ES2239707T3/es not_active Expired - Lifetime
- 2002-03-01 WO PCT/DK2002/000134 patent/WO2002069969A1/en not_active Application Discontinuation
- 2002-03-01 DE DE60203997T patent/DE60203997T2/de not_active Expired - Fee Related
-
2003
- 2003-09-01 NO NO20033855A patent/NO20033855D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1363633B1 (de) | 2005-05-04 |
| DK1363633T3 (da) | 2005-05-30 |
| DK200100341A (da) | 2002-09-03 |
| ES2239707T3 (es) | 2005-10-01 |
| US20040072912A1 (en) | 2004-04-15 |
| ATE294580T1 (de) | 2005-05-15 |
| DE60203997T2 (de) | 2006-02-23 |
| CA2439460A1 (en) | 2002-09-12 |
| AU2002233182B2 (en) | 2004-10-14 |
| PT1363633E (pt) | 2005-09-30 |
| NO20033855L (no) | 2003-09-01 |
| EP1363633A1 (de) | 2003-11-26 |
| WO2002069969A1 (en) | 2002-09-12 |
| NO20033855D0 (no) | 2003-09-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |