HRP20000408B1 - 5-/4-/2-(n-metil-n-(2-piridil)amino)etoksi/benzil/tiazolidin-2,4-dion, sol maleinske kiseline, hidrat kao farmaceutik - Google Patents

5-/4-/2-(n-metil-n-(2-piridil)amino)etoksi/benzil/tiazolidin-2,4-dion, sol maleinske kiseline, hidrat kao farmaceutik

Info

Publication number
HRP20000408B1
HRP20000408B1 HR20000408A HRP20000408A HRP20000408B1 HR P20000408 B1 HRP20000408 B1 HR P20000408B1 HR 20000408 A HR20000408 A HR 20000408A HR P20000408 A HRP20000408 A HR P20000408A HR P20000408 B1 HRP20000408 B1 HR P20000408B1
Authority
HR
Croatia
Prior art keywords
thiazolidine
pyridyl
hydrate
ethoxy
benzyl
Prior art date
Application number
HR20000408A
Other languages
English (en)
Croatian (hr)
Inventor
David James Blackler Paul
C. Lee David
John Sasse Michael
Original Assignee
Smithkline Beecham P.L.C.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham P.L.C. filed Critical Smithkline Beecham P.L.C.
Publication of HRP20000408A2 publication Critical patent/HRP20000408A2/hr
Publication of HRP20000408B1 publication Critical patent/HRP20000408B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HR20000408A 1997-12-16 1998-12-14 5-/4-/2-(n-metil-n-(2-piridil)amino)etoksi/benzil/tiazolidin-2,4-dion, sol maleinske kiseline, hidrat kao farmaceutik HRP20000408B1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9726566.4A GB9726566D0 (en) 1997-12-16 1997-12-16 Novel pharmaceutical
PCT/EP1998/008155 WO1999031095A1 (en) 1997-12-16 1998-12-14 5-[4-[2- (n-methyl-n- (2-pyridyl)amino) ethoxy]benzyl] thiazolidine-2, 4-dione, maleic acid salt, hydrate as pharmaceutical

Publications (2)

Publication Number Publication Date
HRP20000408A2 HRP20000408A2 (en) 2000-08-31
HRP20000408B1 true HRP20000408B1 (hr) 2008-04-30

Family

ID=10823692

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20000408A HRP20000408B1 (hr) 1997-12-16 1998-12-14 5-/4-/2-(n-metil-n-(2-piridil)amino)etoksi/benzil/tiazolidin-2,4-dion, sol maleinske kiseline, hidrat kao farmaceutik

Country Status (35)

Country Link
EP (2) EP1040110A1 (enExample)
JP (1) JP2002508373A (enExample)
KR (1) KR100549142B1 (enExample)
CN (3) CN101381367A (enExample)
AP (1) AP1365A (enExample)
AR (1) AR017214A1 (enExample)
AU (1) AU1967999A (enExample)
BG (1) BG64988B1 (enExample)
BR (1) BR9813600A (enExample)
CA (1) CA2314107A1 (enExample)
CO (1) CO4980880A1 (enExample)
CZ (1) CZ299965B6 (enExample)
DZ (1) DZ2681A1 (enExample)
EA (1) EA004260B1 (enExample)
EG (1) EG22337A (enExample)
GB (1) GB9726566D0 (enExample)
HR (1) HRP20000408B1 (enExample)
HU (1) HUP0100509A3 (enExample)
IL (1) IL136424A (enExample)
IN (1) IN192487B (enExample)
MA (1) MA26580A1 (enExample)
MY (1) MY135612A (enExample)
NO (1) NO317254B1 (enExample)
OA (1) OA11766A (enExample)
PE (1) PE20000058A1 (enExample)
PL (1) PL341146A1 (enExample)
RS (1) RS50126B (enExample)
SA (1) SA99191115B1 (enExample)
SK (1) SK286618B6 (enExample)
TR (2) TR200001799T2 (enExample)
TW (1) TW509690B (enExample)
UA (1) UA72198C2 (enExample)
UY (2) UY25308A1 (enExample)
WO (1) WO1999031095A1 (enExample)
ZA (1) ZA9811506B (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6664278B2 (en) 1997-12-16 2003-12-16 Smithkline Beecham P.L.C. Hydrate of 5-[4-[2-(N-methyl-N-(2-pyridil)amino)ethoxy]benzyl]thiazolidine-2,4-dione maleic acid salt
GB9726568D0 (en) 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel pharmaceutical
GB9909041D0 (en) * 1999-04-20 1999-06-16 Smithkline Beecham Plc Novel pharmaceutical
AR023561A1 (es) * 1999-04-23 2002-09-04 Smithkline Beecham Corp Una forma polimorfica del acido maleico de un derivado de tiazolidin-2, 4 diona, una composicion farmaceutica y el uso de dicho polimorfo para lafabricacion de un medicamento
CZ20013801A3 (cs) * 1999-04-23 2002-07-17 Smithkline Beecham Plc Nový léčivý přípravek
HRP20010773B1 (en) 1999-04-23 2005-06-30 Smithkline Beecham P.L.C. Thiazolidinedione derivative and its use as antidiabetic
AU4882801A (en) * 2000-04-25 2001-11-07 Kyorin Pharmaceutical Co. Ltd. Novel stable crystal of thiazolidinedione derivative and process for producing the same
GB0014005D0 (en) * 2000-06-08 2000-08-02 Smithkline Beecham Plc Novel pharmaceutical
GB0021784D0 (en) * 2000-09-05 2000-10-18 Smithkline Beecham Plc Novel pharmaceutical
GB0021978D0 (en) * 2000-09-07 2000-10-25 Smithkline Beecham Plc Novel pharmaceutical
RU2286345C2 (ru) * 2000-09-26 2006-10-27 Др. Редди'З Лабораториз Лимитед Полиморфные кристаллические формы 5-[4-2-[n-метил-n-(2-пиридил)амино]этокси]бензил]тиазолидин-2,4-дион малеата
CA2426117A1 (en) * 2000-09-26 2002-04-04 Dr. Reddy's Laboratories Limited Novel polymorphic forms of 5-[4-[2-[n-methyl-n-(2-pyridyl)amino]ethoxy]benzyl] thiazolidine-2,4-dione maleate and process for their preparation
GB0129876D0 (en) * 2001-12-13 2002-02-06 Smithkline Beecham Plc Novel pharmaceutical
GB0129872D0 (en) * 2001-12-13 2002-02-06 Smithkline Beecham Plc Novel pharmaceutical
WO2003050112A1 (en) * 2001-12-13 2003-06-19 Smithkline Beecham Plc Toluenesulfonate hydrates of a thiazolidinedione derivative
GB2405403A (en) * 2003-08-29 2005-03-02 Cipla Ltd Rosiglitazone maleate of particular polymorphic forms and methods of preparing rosiglitazone free base
ITMI20041537A1 (it) * 2004-07-28 2004-10-28 Chemi Spa Nuova forma polimorfa del rosiglitazone maleato
CZ298424B6 (cs) * 2005-05-24 2007-09-26 Zentiva, A. S. Zpusob krystalizace rosiglitazonu a jeho derivátuze smesných rozpouštedel
EP2184055A1 (en) 2008-11-07 2010-05-12 LEK Pharmaceuticals d.d. Process for preparing solid dosage forms of rosiglitazone maleate

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE186724T1 (de) * 1987-09-04 1999-12-15 Beecham Group Plc Substituierte thiazolidindionderivate
GB8820389D0 (en) * 1988-08-26 1988-09-28 Beecham Group Plc Novel compounds
GB9218830D0 (en) 1992-09-05 1992-10-21 Smithkline Beecham Plc Novel compounds
WO1995021608A1 (en) * 1994-02-10 1995-08-17 Smithkline Beecham Plc Use of insulin sensitisers for treating renal diseases

Also Published As

Publication number Publication date
CN101381367A (zh) 2009-03-11
AR017214A1 (es) 2001-08-22
KR20010033141A (ko) 2001-04-25
NO20003069D0 (no) 2000-06-15
UY25308A1 (es) 1999-07-19
CN1281453A (zh) 2001-01-24
HRP20000408A2 (en) 2000-08-31
PL341146A1 (en) 2001-03-26
NO20003069L (no) 2000-06-15
AP1365A (en) 2005-01-26
UY25304A1 (es) 2000-12-29
SK286618B6 (sk) 2009-02-05
YU36300A (sh) 2004-03-12
IL136424A0 (en) 2001-06-14
BG104603A (en) 2001-03-30
CN101302215A (zh) 2008-11-12
TR199802625A2 (xx) 1999-10-21
EP1040110A1 (en) 2000-10-04
HUP0100509A2 (hu) 2002-05-29
RS50126B (sr) 2009-03-25
MY135612A (en) 2008-05-30
HUP0100509A3 (en) 2002-06-28
UA72198C2 (en) 2005-02-15
PE20000058A1 (es) 2000-02-26
CZ299965B6 (cs) 2009-01-07
AP2000001831A0 (en) 2000-06-30
EP1661895A1 (en) 2006-05-31
TR200001799T2 (tr) 2001-01-22
CA2314107A1 (en) 1999-06-24
WO1999031095A1 (en) 1999-06-24
TR199802625A3 (tr) 1999-10-21
IN192487B (enExample) 2004-04-24
SA99191115B1 (ar) 2006-10-11
CO4980880A1 (es) 2000-11-27
EA004260B1 (ru) 2004-02-26
BG64988B1 (bg) 2006-11-30
AU1967999A (en) 1999-07-05
EA200000654A1 (ru) 2000-12-25
KR100549142B1 (ko) 2006-02-03
IL136424A (en) 2003-12-10
DZ2681A1 (fr) 2004-06-20
BR9813600A (pt) 2000-10-10
OA11766A (en) 2005-07-19
NO317254B1 (no) 2004-09-27
MA26580A1 (fr) 2004-12-20
CZ20002204A3 (cs) 2000-11-15
JP2002508373A (ja) 2002-03-19
GB9726566D0 (en) 1998-02-11
SK9172000A3 (en) 2001-01-18
EG22337A (en) 2002-12-31
TW509690B (en) 2002-11-11
ZA9811506B (en) 2000-11-06

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Payment date: 20081121

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Effective date: 20091215