EA200101101A1 - Новый фармацевтический препарат - Google Patents

Новый фармацевтический препарат

Info

Publication number
EA200101101A1
EA200101101A1 EA200101101A EA200101101A EA200101101A1 EA 200101101 A1 EA200101101 A1 EA 200101101A1 EA 200101101 A EA200101101 A EA 200101101A EA 200101101 A EA200101101 A EA 200101101A EA 200101101 A1 EA200101101 A1 EA 200101101A1
Authority
EA
Eurasian Patent Office
Prior art keywords
compound
pharmaceutical preparation
new pharmaceutical
gives
containing peaks
Prior art date
Application number
EA200101101A
Other languages
English (en)
Other versions
EA004232B1 (ru
Inventor
Пол Дэвид Джеймс Блэклер
Робер Гордон Жиль
Майкл Джон Сасс
Original Assignee
Смитклайн Бичам Плс
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Смитклайн Бичам Плс filed Critical Смитклайн Бичам Плс
Publication of EA200101101A1 publication Critical patent/EA200101101A1/ru
Publication of EA004232B1 publication Critical patent/EA004232B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Настоящее изобретение раскрывает 5-[4-[2-(N-метил-N-(2-пиридил)амино)этокси]бензил]тиазолидин-2,4-дион, гидрохлорид дигидрат, отличающийся тем, что он: (i) дает инфракрасный спектр, содержащий пики при 3392, 2739, 1751, 1325 и 713 см; и/или (ii) дает порошковую рентгенограмму (ПР), содержащую пики при 9,1; 12,0; 15,7; 16,3 и 19,8 °2θ; способ получения такого соединения, фармацевтическую композицию, содержащую такое соединение, и применение такого соединения в медицине.Отчет о международном поиске был опубликован 2001.01.25.
EA200101101A 1999-04-20 2000-04-19 Новый фармацевтический препарат EA004232B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9909041.7A GB9909041D0 (en) 1999-04-20 1999-04-20 Novel pharmaceutical
PCT/GB2000/001521 WO2000063205A2 (en) 1999-04-20 2000-04-19 Thiazolidinedione derivative and its use as antidiabetic

Publications (2)

Publication Number Publication Date
EA200101101A1 true EA200101101A1 (ru) 2002-04-25
EA004232B1 EA004232B1 (ru) 2004-02-26

Family

ID=10851901

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200101101A EA004232B1 (ru) 1999-04-20 2000-04-19 Новый фармацевтический препарат

Country Status (42)

Country Link
EP (2) EP1173436B1 (ru)
JP (2) JP4283449B2 (ru)
KR (1) KR100601244B1 (ru)
CN (2) CN101134756A (ru)
AP (1) AP1562A (ru)
AR (2) AR023562A1 (ru)
AT (1) ATE268770T1 (ru)
AU (2) AU4130900A (ru)
BG (1) BG65864B1 (ru)
BR (1) BR0009897A (ru)
CA (1) CA2382036A1 (ru)
CO (1) CO5170422A1 (ru)
CZ (1) CZ300653B6 (ru)
DE (1) DE60011419T2 (ru)
DK (1) DK1173436T3 (ru)
DZ (1) DZ3162A1 (ru)
EA (1) EA004232B1 (ru)
EG (1) EG24063A (ru)
ES (1) ES2218146T3 (ru)
GB (1) GB9909041D0 (ru)
HK (1) HK1045151B (ru)
HR (1) HRP20010770B1 (ru)
HU (1) HUP0200865A3 (ru)
IL (1) IL146078A0 (ru)
MA (1) MA26783A1 (ru)
MX (1) MXPA01010696A (ru)
MY (1) MY126034A (ru)
NO (1) NO320609B1 (ru)
NZ (1) NZ515166A (ru)
OA (1) OA11866A (ru)
PE (1) PE20010050A1 (ru)
PL (1) PL351135A1 (ru)
PT (1) PT1173436E (ru)
RS (1) RS50136B (ru)
SI (1) SI1173436T1 (ru)
SK (1) SK284991B6 (ru)
TR (1) TR200103040T2 (ru)
TW (1) TWI277616B (ru)
UA (1) UA71615C2 (ru)
UY (1) UY26112A1 (ru)
WO (1) WO2000063205A2 (ru)
ZA (1) ZA200108720B (ru)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9909041D0 (en) * 1999-04-20 1999-06-16 Smithkline Beecham Plc Novel pharmaceutical
GB0006133D0 (en) 2000-03-14 2000-05-03 Smithkline Beecham Plc Novel pharmaceutical
GB0014005D0 (en) * 2000-06-08 2000-08-02 Smithkline Beecham Plc Novel pharmaceutical
WO2003045946A1 (en) * 2001-11-21 2003-06-05 Smithkline Beecham P.L.C. 5-(4-(2-(n-methyl-n-(2-pyridil) amino) ethoxy) benzyl) thiazolidine-2, 4-dione benzenesulfonate; process for its preparation; polymorphs i, ii and iii thereof; and its use as pharmaceutical active ingredient
GB0129872D0 (en) * 2001-12-13 2002-02-06 Smithkline Beecham Plc Novel pharmaceutical
CZ296468B6 (cs) * 2004-06-10 2006-03-15 Zentiva, A. S. Sul kyseliny fosforecné s 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidin-2,4-dionema zpusob její prípravy
CZ2004844A3 (cs) * 2004-07-27 2006-03-15 Zentiva, A. S Sul kyseliny stavelové s 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidin-2,4-dionu azpusob její prípravy a její pouzití
CZ298424B6 (cs) * 2005-05-24 2007-09-26 Zentiva, A. S. Zpusob krystalizace rosiglitazonu a jeho derivátuze smesných rozpouštedel
EP1842850A1 (en) * 2006-03-23 2007-10-10 Sandoz AG Rosiglitazone hydrochloride hemihydrate

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2137915T3 (es) * 1987-09-04 2000-01-01 Beecham Group Plc Derivados de tiazolidindiona sustituida.
GB9218830D0 (en) * 1992-09-05 1992-10-21 Smithkline Beecham Plc Novel compounds
GB9726568D0 (en) * 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel pharmaceutical
GB9726566D0 (en) * 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel pharmaceutical
GB9726563D0 (en) * 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel pharmaceutical
GB9909041D0 (en) * 1999-04-20 1999-06-16 Smithkline Beecham Plc Novel pharmaceutical

Also Published As

Publication number Publication date
ES2218146T3 (es) 2004-11-16
EP1411055A1 (en) 2004-04-21
TWI277616B (en) 2007-04-01
PL351135A1 (en) 2003-03-24
WO2000063205A3 (en) 2001-01-25
DE60011419D1 (de) 2004-07-15
JP2009143954A (ja) 2009-07-02
CN101134756A (zh) 2008-03-05
SK284991B6 (sk) 2006-04-06
MA26783A1 (fr) 2004-12-20
OA11866A (en) 2006-03-02
HRP20010770A2 (en) 2002-10-31
BR0009897A (pt) 2002-04-16
WO2000063205A2 (en) 2000-10-26
MY126034A (en) 2006-09-29
BG65864B1 (bg) 2010-03-31
AU765911B2 (en) 2003-10-02
PE20010050A1 (es) 2001-03-10
YU81501A (sh) 2004-07-15
CZ300653B6 (cs) 2009-07-08
EG24063A (en) 2008-05-08
RS50136B (sr) 2009-03-25
EP1173436B1 (en) 2004-06-09
EP1173436A2 (en) 2002-01-23
CA2382036A1 (en) 2000-10-26
HK1045151A1 (en) 2002-11-15
HUP0200865A3 (en) 2005-04-28
ZA200108720B (en) 2002-11-28
NO320609B1 (no) 2005-12-27
NO20015104L (no) 2001-12-19
AR023566A1 (es) 2002-09-04
CZ20013759A3 (cs) 2002-05-15
BG106112A (bg) 2002-05-31
HK1045151B (zh) 2005-03-18
CO5170422A1 (es) 2002-06-27
HRP20010770B1 (en) 2005-06-30
DE60011419T2 (de) 2005-06-16
UY26112A1 (es) 2000-12-29
DK1173436T3 (da) 2004-09-27
AR023562A1 (es) 2002-09-04
MXPA01010696A (es) 2002-06-04
PT1173436E (pt) 2004-10-29
CN1327447A (zh) 2001-12-19
AU2755202A (en) 2002-05-16
KR100601244B1 (ko) 2006-07-19
EA004232B1 (ru) 2004-02-26
JP4283449B2 (ja) 2009-06-24
SK14902001A3 (sk) 2002-02-05
AP2001002331A0 (en) 2000-04-19
NO20015104D0 (no) 2001-10-19
KR20010110791A (ko) 2001-12-13
DZ3162A1 (fr) 2000-10-26
ATE268770T1 (de) 2004-06-15
HUP0200865A2 (en) 2002-08-28
TR200103040T2 (tr) 2002-04-22
AP1562A (en) 2006-02-01
IL146078A0 (en) 2002-07-25
GB9909041D0 (en) 1999-06-16
AU4130900A (en) 2000-11-02
JP2002542242A (ja) 2002-12-10
UA71615C2 (ru) 2004-12-15
NZ515166A (en) 2004-02-27
SI1173436T1 (en) 2004-12-31

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU

NF4A Restoration of lapsed right to a eurasian patent

Designated state(s): AM AZ BY KZ KG MD TJ TM RU

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM BY KZ MD TJ RU