ZA981732B - Process for the preparation of 2-[[(2-pyridinyl)methyl]-sulfinyl]-1H-benzimidazoles and novel compounds of use for such purpose - Google Patents

Process for the preparation of 2-[[(2-pyridinyl)methyl]-sulfinyl]-1H-benzimidazoles and novel compounds of use for such purpose

Info

Publication number
ZA981732B
ZA981732B ZA981732A ZA981732A ZA981732B ZA 981732 B ZA981732 B ZA 981732B ZA 981732 A ZA981732 A ZA 981732A ZA 981732 A ZA981732 A ZA 981732A ZA 981732 B ZA981732 B ZA 981732B
Authority
ZA
South Africa
Prior art keywords
benzimidazoles
sulfinyl
pyridinyl
methyl
preparation
Prior art date
Application number
ZA981732A
Inventor
Finn Priess Clausen
Klaus Karl Mccluskey
Herbert Fritz Preikschat
Soren Bols Pedersen
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of ZA981732B publication Critical patent/ZA981732B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA981732A 1997-03-07 1998-03-02 Process for the preparation of 2-[[(2-pyridinyl)methyl]-sulfinyl]-1H-benzimidazoles and novel compounds of use for such purpose ZA981732B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK25097 1997-03-07

Publications (1)

Publication Number Publication Date
ZA981732B true ZA981732B (en) 1998-09-07

Family

ID=8091429

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA981732A ZA981732B (en) 1997-03-07 1998-03-02 Process for the preparation of 2-[[(2-pyridinyl)methyl]-sulfinyl]-1H-benzimidazoles and novel compounds of use for such purpose

Country Status (6)

Country Link
EP (1) EP0968205A1 (en)
AU (1) AU5982298A (en)
HR (1) HRP980115A2 (en)
NO (1) NO994340L (en)
WO (1) WO1998040378A1 (en)
ZA (1) ZA981732B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE510643C2 (en) * 1997-06-27 1999-06-14 Astra Ab Thermodynamically stable omeprazole sodium form B
US6191148B1 (en) 1998-08-11 2001-02-20 Merck & Co., Inc. Omerazole process and compositions thereof
US6166213A (en) * 1998-08-11 2000-12-26 Merck & Co., Inc. Omeprazole process and compositions thereof
US20020128232A1 (en) * 2000-10-12 2002-09-12 Henderson Scott A. Heterocyclic angiogenesis inhibitors
EP1572680A2 (en) 2002-12-19 2005-09-14 Eva Pharmaceutical Industries Ltd. Solid states of pantoprazole sodium, known pantoprazole sodium hydrates, processes for their preparation.
US7683177B2 (en) 2003-06-10 2010-03-23 Teva Pharmaceutical Industries Ltd Process for preparing 2-[(pyridinyl)methyl]sulfinyl-substituted benzimidazoles and novel chlorinated derivatives of pantoprazole
SE0400410D0 (en) * 2004-02-20 2004-02-20 Astrazeneca Ab New compounds
EP1921075B1 (en) * 2006-10-30 2010-03-03 Dipharma Francis S.r.l. A process for the preparation of pyridine-methylsulfinyl compounds
EP2022789A1 (en) * 2007-08-06 2009-02-11 Farmaprojects, S.A. Process for the preparation of a gastric acid secretion inhibitor
CN102964336B (en) * 2012-11-29 2014-08-06 寿光富康制药有限公司 Refining method of proton pump inhibitor and reducing method of N-oxide of proton pump inhibitor
CN103044401A (en) * 2012-12-21 2013-04-17 北京华禧联合科技发展有限公司 Preparation method of benzimidazole compound
CN103951651B (en) * 2014-03-24 2018-11-30 翰宇药业（武汉）有限公司 The synthetic method of Rabeprazole correlative D
CN105111187B (en) * 2015-08-07 2017-08-25 齐鲁天和惠世制药有限公司 A kind of preparation method of Pantoprazole Sodium nitrogen oxidation impurity

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD231787A1 (en) * 1984-08-10 1986-01-08 Akad Wissenschaften Ddr PROCESS FOR PRODUCING OMEGA-SUBSTITUTED BZW. OMEGA, OMEGA-DISUBSTITUTED 2-METHYLTHIO-BENZIMIDAZOLE DERIVATIVES
ES2026761A6 (en) * 1990-10-31 1992-05-01 Genesis Para La Investigacion A process for the preparation of omeprazol.

Also Published As

Publication number Publication date
NO994340D0 (en) 1999-09-07
NO994340L (en) 1999-09-07
EP0968205A1 (en) 2000-01-05
WO1998040378A1 (en) 1998-09-17
HRP980115A2 (en) 1999-02-28
AU5982298A (en) 1998-09-29

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