HK75493A - Procaryotic carbonyl hydrolases,methods,dna,vectors and transformed hosts for producing them,and detergent compositions containing them - Google Patents

Procaryotic carbonyl hydrolases,methods,dna,vectors and transformed hosts for producing them,and detergent compositions containing them

Info

Publication number
HK75493A
HK75493A HK754/93A HK75493A HK75493A HK 75493 A HK75493 A HK 75493A HK 754/93 A HK754/93 A HK 754/93A HK 75493 A HK75493 A HK 75493A HK 75493 A HK75493 A HK 75493A
Authority
HK
Hong Kong
Prior art keywords
dna
vectors
producing
methods
compositions containing
Prior art date
Application number
HK754/93A
Other languages
English (en)
Inventor
Richard Ray Bott
Eugenio Ferrari
James Allen Wells
David Aaron Estell
Dennis James Henner
Original Assignee
Genencor Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27560079&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK75493(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US06/614,612 external-priority patent/US4760025A/en
Application filed by Genencor Int filed Critical Genencor Int
Publication of HK75493A publication Critical patent/HK75493A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102Mutagenizing nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/07Bacillus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Detergent Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HK754/93A 1983-06-24 1993-07-29 Procaryotic carbonyl hydrolases,methods,dna,vectors and transformed hosts for producing them,and detergent compositions containing them HK75493A (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US50741983A 1983-06-24 1983-06-24
US61461684A 1984-05-29 1984-05-29
US61461584A 1984-05-29 1984-05-29
US61449184A 1984-05-29 1984-05-29
US61461784A 1984-05-29 1984-05-29
US06/614,612 US4760025A (en) 1984-05-29 1984-05-29 Modified enzymes and methods for making same

Publications (1)

Publication Number Publication Date
HK75493A true HK75493A (en) 1993-08-06

Family

ID=27560079

Family Applications (3)

Application Number Title Priority Date Filing Date
HK753/93A HK75393A (en) 1983-06-24 1993-07-29 Dna mutagenesis method
HK754/93A HK75493A (en) 1983-06-24 1993-07-29 Procaryotic carbonyl hydrolases,methods,dna,vectors and transformed hosts for producing them,and detergent compositions containing them
HK992/93A HK99293A (en) 1983-06-24 1993-09-23 Bacillus incapable of excreting subtilisin or neutral protease

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK753/93A HK75393A (en) 1983-06-24 1993-07-29 Dna mutagenesis method

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK992/93A HK99293A (en) 1983-06-24 1993-09-23 Bacillus incapable of excreting subtilisin or neutral protease

Country Status (8)

Country Link
EP (4) EP0130756B2 (fr)
JP (3) JP2594533B2 (fr)
AT (2) ATE60356T1 (fr)
DE (3) DE3484079D1 (fr)
DK (3) DK175278B1 (fr)
HK (3) HK75393A (fr)
IE (1) IE81141B1 (fr)
NZ (1) NZ208612A (fr)

Families Citing this family (221)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ208612A (en) 1983-06-24 1991-09-25 Genentech Inc Method of producing "procaryotic carbonyl hydrolases" containing predetermined, site specific mutations
CA1311429C (fr) * 1983-07-06 1992-12-15 Vasantha Nagarajan Vecteur pour polypeptides dans les bacilles
JPH0659224B2 (ja) * 1983-09-12 1994-08-10 工業技術院長 Dνa塩基配列及びそのdνa塩基配列を含む組換え体プラスミドの創製法
EP0462632A1 (fr) * 1983-10-28 1991-12-27 Genetics Institute, Inc. Procédé de préparation d'une protéine humaine choisie par des techniques de l'ADN recombinante
JPH07106156B2 (ja) * 1983-10-28 1995-11-15 ジェネティックス、インスティチュ−ト ファクタ−▲viii▼および関連生産物の製造
DE3484346D1 (de) * 1983-12-28 1991-05-02 Agency Ind Science Techn Dns-basensequenz enthaltende regionen einbegriffen in der herstellung und sekretion eines proteins, rekombinante dns das ganze oder einen teil der dns-basensequenz enthaltend und verfahren zur herstellung von proteinen unter verwendung der rekombinanten dns.
US5411873A (en) * 1984-05-29 1995-05-02 Genencor, Inc. Process for producing heterologous polypeptides
US5972682A (en) * 1984-05-29 1999-10-26 Genencor International, Inc. Enzymatically active modified subtilisins
US5185258A (en) * 1984-05-29 1993-02-09 Genencor International, Inc. Subtilisin mutants
US4801537A (en) * 1984-06-08 1989-01-31 Genex Corporation Vector for expression of polypeptides in bacilli
US5840522A (en) * 1984-09-20 1998-11-24 Chiron Corporation Recombinant lectins
US4828994A (en) * 1984-09-21 1989-05-09 Genex Corporation Bacillus strains with reduced extracellular protease levels
CA1340265C (fr) * 1985-01-18 1998-12-15 Kirston E. Koths Muteines resistant a l'oxydation
US4752585A (en) * 1985-12-17 1988-06-21 Cetus Corporation Oxidation-resistant muteins
US6084073A (en) * 1985-03-25 2000-07-04 Chiron Corporation Recombinant ricin toxin
EP0316018A3 (fr) * 1985-03-29 1989-07-26 Cetus Oncology Corporation Modification de séquences d'ADN
ATE77648T1 (de) * 1985-04-15 1992-07-15 Procter & Gamble Fluessige reinigungsmittel mit einer anionischen oberflaechenaktiven verbindung, einem verstaerker und einem proteolytischen enzym.
DE3685769T2 (de) * 1985-04-15 1993-01-21 Procter & Gamble Fluessige reinigungsmittel mit einer oberflaechenaktiven verbindung, einem proteolytischen enzym und borsaeure.
IT1186750B (it) * 1985-07-10 1987-12-16 Eniricerche Spa Vettore di clonaggio,molecole di dna ricombinante,ceppi di bacillus subtilis trasformati con dette molecole e metodi per l'espressione di geni eterologhi e produzione e secrezione di proteine codificate da detti geni
DE3527913A1 (de) * 1985-08-03 1987-02-12 Henkel Kgaa Alkalische protease, verfahren zur herstellung von hybridvektoren und genetisch transformierte mikroorganismen
JP2599946B2 (ja) * 1986-01-15 1997-04-16 アムジェン,インコーポレイテツド ズブチリシン類似体
US5013657A (en) * 1988-04-12 1991-05-07 Bryan Philip N Subtilisin mutations
US4908773A (en) * 1987-04-06 1990-03-13 Genex Corporation Computer designed stabilized proteins and method for producing same
ATE116365T1 (de) * 1986-04-30 1995-01-15 Genencor Int Mutante einer nicht menschlichen carbonyl- hydrolase, für diese kodierende dns-sequenzen und vektoren und durch diese vektoren transformierte wirte.
DE3781017T2 (de) * 1986-05-06 1993-03-18 Univ Leland Stanford Junior Cytotoxische zusammensetzung aus "killer"-zellen.
US5364554A (en) * 1986-06-09 1994-11-15 The Clorox Company Proteolytic perhydrolysis system and method of use for bleaching
EP0260350B1 (fr) * 1986-09-05 1992-02-12 Cetus Oncology Corporation Mutéines d'interféron-bêta résistant à l'oxydation, leur production; préparations contenant ces mutéines
NZ221627A (en) * 1986-09-09 1993-04-28 Genencor Inc Preparation of enzymes, modifications, catalytic triads to alter ratios or transesterification/hydrolysis ratios
RU2091487C1 (ru) * 1987-02-27 1997-09-27 Гист-Брокейдс Н.В. Способ получения штамма bacillus, содержащего две копии последовательности днк, кодирующей фермент с гидролазной активностью
PT86864B (pt) * 1987-02-27 1992-05-29 Gist Brocades Nv Processo para clonagem molecular e expressao de genes que codificam para enzimas proteoliticas
EP0896062A3 (fr) * 1987-02-27 1999-04-07 Genencor International, Inc. Transformation de souches de Bacillus alcalophiles
EP0285123A3 (fr) * 1987-04-03 1989-02-01 Stabra AG Méthode de mutagénèse complète d'acides nucléiques
ATE184316T1 (de) * 1987-04-06 1999-09-15 Novo Nordisk As Regelung von elektrostatischen interaktionen an metallionen-bindungsstellen zur stabilisierung von proteinen
US4853871A (en) * 1987-04-06 1989-08-01 Genex Corporation Computer-based method for designing stablized proteins
US4914031A (en) * 1987-04-10 1990-04-03 Amgen, Inc. Subtilisin analogs
IT1228925B (it) * 1987-08-07 1991-07-10 Eniricerche Spa Procedimento per la preparazione dell'ormone della crescita umano
US5041378A (en) * 1987-08-11 1991-08-20 Cetus Corporation Procaryotic xylose isomerase muteins
US4939666A (en) * 1987-09-02 1990-07-03 Genex Corporation Incremental macromolecule construction methods
US4966846A (en) * 1987-10-01 1990-10-30 W. R. Grace & Co.-Conn. Molecular cloning and expression of a vibrio proteolyticus neutral protease gene
DK571587D0 (da) * 1987-11-02 1987-11-02 Novo Industri As Enzymatisk detergentsammensaetning
GB8727772D0 (en) * 1987-11-27 1987-12-31 Celltech Ltd Host cells
US4865983A (en) * 1987-12-04 1989-09-12 W. R. Grace & Co.-Conn. Cleaning compositions containing protease produced by vibrio and method of use
DE3877337T2 (de) * 1987-12-11 1993-08-19 Abbott Lab Verfahren zur mutagenese mittels oligonukleotid-gerichteter reparatur eines strandbruchs.
DK6488D0 (da) * 1988-01-07 1988-01-07 Novo Industri As Enzymer
US6287841B1 (en) 1988-02-11 2001-09-11 Genencor International, Inc. High alkaline serine protease
PT89702B (pt) * 1988-02-11 1994-04-29 Gist Brocades Nv Processo para a preparacao de novos enzimas proteoliticos e de detergentes que os contem
US5324653A (en) * 1988-02-11 1994-06-28 Gist-Brocades N.V. Recombinant genetic means for the production of serine protease muteins
US5246849A (en) * 1988-04-12 1993-09-21 Enzon, Inc. Thermally stable serine proteases
US5118623A (en) * 1988-05-27 1992-06-02 Solvay Enzymes, Inc. Bleach stable enzymes
CA1333777C (fr) 1988-07-01 1995-01-03 Randy M. Berka Champignons filamenteux deficients en proteinase aspartique
HU200796B (en) * 1988-07-14 1990-08-28 Richter Gedeon Vegyeszet Process for producing expression vectors ensuring insertion of nucleotide sequences into e. coli chromosome
US5665587A (en) * 1989-06-26 1997-09-09 Novo Nordisk A/S Modified subtilisins and detergent compositions containing same
US5658871A (en) * 1989-07-07 1997-08-19 Lever Brothers Company, Division Of Conopco, Inc. Microbial lipase muteins and detergent compositions comprising same
GB8915658D0 (en) * 1989-07-07 1989-08-23 Unilever Plc Enzymes,their production and use
NL8902010A (nl) * 1989-08-04 1991-03-01 Nl Zuivelonderzoek Inst Dna-fragment met ten minste een protease-gen, een dergelijk dna-fragment bevattende cloneringsvektor, een gastheercel getransformeerd met een dusdanig opgebouwde cloneringsvektor, alsmede de met dergelijke gastheercellen geproduceerde proteasen resp. bereide produkten zoals voedingsmiddelen.
EP0414297B1 (fr) * 1989-08-11 1996-10-16 Gist-Brocades N.V. Production effective de protéases mutantes
DE4023458A1 (de) * 1989-08-31 1991-03-07 Kali Chemie Ag Neue hochalkalische proteasen
US5352603A (en) * 1989-08-31 1994-10-04 Kali-Chemie Ag Highly alkaline proteases
US6271012B1 (en) * 1989-10-11 2001-08-07 Genencor International, Inc. Protease muteins and their use in detergents
JPH0813271B2 (ja) * 1989-11-27 1996-02-14 日本ケミカルリサーチ株式会社 線溶活性蛋白質およびその製造法
US5030378A (en) * 1990-01-02 1991-07-09 The Procter & Gamble Company Liquid detergents containing anionic surfactant, builder and proteolytic enzyme
ATE310080T1 (de) * 1990-01-04 2005-12-15 Genencor Int Glucose-isomerase mit geändertem ph-optimum
IT1239733B (it) * 1990-02-23 1993-11-15 Eniricerche Spa Mutanti della proteasi neutra termostabili e mezzi e metodi per la loro preparazione
DK271490D0 (da) * 1990-11-14 1990-11-14 Novo Nordisk As Detergentkomposition
DE4037530A1 (de) * 1990-11-26 1992-05-27 Henkel Kgaa Faellungsverfahren fuer exocellulaere proteine
US5482849A (en) * 1990-12-21 1996-01-09 Novo Nordisk A/S Subtilisin mutants
US5340735A (en) * 1991-05-29 1994-08-23 Cognis, Inc. Bacillus lentus alkaline protease variants with increased stability
WO1993001282A1 (fr) * 1991-07-01 1993-01-21 Berlex Laboratories, Inc. Nouveaux procedes et compositions pour mutagenese
US5770410A (en) * 1992-01-30 1998-06-23 Genzyme Corporation Chiral synthesis with modified enzymes
JP3431146B2 (ja) * 1992-01-30 2003-07-28 ジェンザイム・リミテッド 改変した酵素によるキラル合成
US5316935A (en) * 1992-04-06 1994-05-31 California Institute Of Technology Subtilisin variants suitable for hydrolysis and synthesis in organic media
US5869644A (en) * 1992-04-15 1999-02-09 The Johns Hopkins University Synthesis of diverse and useful collections of oligonucleotidies
MX9302819A (es) * 1992-05-13 1994-07-29 Procter & Gamble Composicion detergente liquida para trabajo pesado.
DE69334295D1 (de) * 1992-07-23 2009-11-12 Novo Nordisk As MUTIERTE -g(a)-AMYLASE, WASCHMITTEL UND GESCHIRRSPÜLMITTEL
AU682863C (en) * 1993-02-11 2003-05-08 Genencor International, Inc. Oxidatively stable alpha-amylase
DK39093D0 (da) * 1993-04-01 1993-04-01 Novo Nordisk As Enzym
US6440717B1 (en) * 1993-09-15 2002-08-27 The Procter & Gamble Company BPN′ variants having decreased adsorption and increased hydrolysis
US6436690B1 (en) * 1993-09-15 2002-08-20 The Procter & Gamble Company BPN′ variants having decreased adsorption and increased hydrolysis wherein one or more loop regions are substituted
WO1995023221A1 (fr) 1994-02-24 1995-08-31 Cognis, Inc. Enzymes ameliorees et detergents les contenant
ES2364774T3 (es) 1994-02-24 2011-09-14 HENKEL AG & CO. KGAA Enzimas mejoradas y detergentes que las contienen.
USH1468H (en) 1994-04-28 1995-08-01 Costa Jill B Detergent compositions containing cellulase enzyme and selected perfumes for improved odor and stability
US6599730B1 (en) * 1994-05-02 2003-07-29 Procter & Gamble Company Subtilisin 309 variants having decreased adsorption and increased hydrolysis
EP0693549A1 (fr) 1994-07-19 1996-01-24 The Procter & Gamble Company Compositions d'activateurs de blanchiment solides
MX9700776A (es) * 1994-08-11 1997-05-31 Genecor Int Inc Composicion de limpieza mejorada.
GB9416841D0 (en) 1994-08-19 1994-10-12 Finnfeeds Int Ltd An enzyme feed additive and animal feed including it
US5780285A (en) * 1995-03-03 1998-07-14 Genentech, Inc. Subtilisin variants capable of cleaving substrates containing dibasic residues
US5837516A (en) * 1995-03-03 1998-11-17 Genentech, Inc. Subtilisin variants capable of cleaving substrates containing basic residues
US6455295B1 (en) * 1995-03-08 2002-09-24 The Procter & Gamble Company Subtilisin Carlsberg variants having decreased adsorption and increased hydrolysis
US6475765B1 (en) * 1995-03-09 2002-11-05 Procter & Gamble Company Subtilisin DY variants having decreased adsorption and increased hydrolysis
IL117350A0 (en) * 1995-03-09 1996-07-23 Procter & Gamble Proteinase k variants having decreased adsorption and increased hydrolysis
US6682924B1 (en) * 1995-05-05 2004-01-27 Novozymes A/S Protease variants and compositions
ES2115338T3 (es) 1995-07-13 1998-06-16 Procter & Gamble Composicion de espumacion para envasado.
EP0753567A1 (fr) 1995-07-14 1997-01-15 The Procter & Gamble Company Compositions adoucissantes pour le lavage simultané
DE19530816A1 (de) 1995-08-23 1997-02-27 Cognis Bio Umwelt Verwendung von mutierter Subtilisin-Protease in kosmetischen Produkten
EP0778342A1 (fr) 1995-12-06 1997-06-11 The Procter & Gamble Company Compositions détergentes
CZ355098A3 (cs) 1996-05-03 1999-04-14 The Procter & Gamble Company Detergentové prostředky s lepší dispergací nečistot, které obsahují polyaminové polymery
US5858948A (en) * 1996-05-03 1999-01-12 Procter & Gamble Company Liquid laundry detergent compositions comprising cotton soil release polymers and protease enzymes
US5958739A (en) * 1996-06-06 1999-09-28 Genencor International Inc. Mutant α-amylase
JP2000506931A (ja) * 1996-09-24 2000-06-06 ザ、プロクター、エンド、ギャンブル、カンパニー タンパク質分解酵素とプロテアーゼインヒビターを含有した液体洗剤
WO1998013461A1 (fr) 1996-09-24 1998-04-02 The Procter & Gamble Company Compositions de detergents liquides pour lessive contenant une enzyme proteolytique et des inhibiteurs de protease
US6165966A (en) * 1996-09-24 2000-12-26 The Procter & Gamble Company Liquid detergents containing proteolytic enzyme and protease inhibitors
JP2000503504A (ja) * 1996-10-29 2000-03-21 フィリップス エレクトロニクス ネムローゼ フェンノートシャップ テレビジョン受像器
US6300116B1 (en) 1996-11-04 2001-10-09 Novozymes A/S Modified protease having improved autoproteolytic stability
WO1998020115A1 (fr) 1996-11-04 1998-05-14 Novo Nordisk A/S Variants et compositions de subtilase
EP0958342B1 (fr) 1996-12-31 2003-07-09 The Procter & Gamble Company Compositions detersives liquides epaissies et fortement aqueuses
BR9714454A (pt) * 1996-12-31 2000-03-21 Procter & Gamble endo fixadores de corante
EP0958341A1 (fr) 1996-12-31 1999-11-24 The Procter & Gamble Company Compositions detersives liquides epaissies, fortement aqueuses, bon marche, contenant des tensioactifs aromatiques
WO1998029530A2 (fr) * 1996-12-31 1998-07-09 The Procter & Gamble Company Compositions de detergent de lessive contenant des polyamide-polyamines pour conferer des qualites esthetiques a des tissus laves avec lesdites compositions
DE19717346C2 (de) * 1997-04-24 1999-05-20 Max Planck Gesellschaft DNA-Sonden, Verfahren und Kit zur Identifizierung Antibiotika-resistenter Bakterienstämme
US6080568A (en) * 1997-08-19 2000-06-27 Genencor International, Inc. Mutant α-amylase comprising modification at residues corresponding to A210, H405 and/or T412 in Bacillus licheniformis
JP2001514846A (ja) 1997-08-29 2001-09-18 ノボ ノルディスク アクティーゼルスカブ プロテアーゼ変異体及び組成物
DE69839076T2 (de) 1997-08-29 2009-01-22 Novozymes A/S Proteasevarianten und zusammensetzungen
US6780629B2 (en) 1997-11-21 2004-08-24 Novozymes A/S Subtilase enzymes
KR100762164B1 (ko) 1997-11-21 2007-10-01 노보자임스 에이/에스 프로테아제 변이체 및 조성물
US6773907B2 (en) 1997-11-21 2004-08-10 Peter Kamp Hansen Subtilase enzymes
EP1021525A1 (fr) 1997-12-20 2000-07-26 Genencor International, Inc. Granules matriciels en lit fluidise
EP1057015A1 (fr) 1997-12-20 2000-12-06 Genencor International, Inc. Essai accelere de stabilite
PL342710A1 (en) 1997-12-20 2001-07-02 Genencor Int Matrix granule
KR20010033321A (ko) 1997-12-20 2001-04-25 마가렛 에이.혼 수화된 차단 재료를 가지는 과립
US6908757B1 (en) 1998-03-26 2005-06-21 The Procter & Gamble Company Serine protease variants having amino acid deletions and substitutions
US6413749B1 (en) 1998-10-27 2002-07-02 Genencor International, Inc. Granule containing protein and corn starch layered on an inert particle
EP1129163B1 (fr) 1998-11-13 2011-01-05 Danisco US Inc. Granule de faible densite sur lit fluidise
DE69943346D1 (de) 1998-12-18 2011-05-19 Novozymes As Subtilase Enzyme der I-S1- und I-S2-Untergruppen mit einem zusätzlichen Aminosäurerest in einer aktiven Schleifenregion
DK1149151T3 (da) 1999-01-08 2006-07-31 Genencor Int Sammensætninger med lav densitet og partikulære dele, der indbefatter dem
DE60040282D1 (de) 1999-05-20 2008-10-30 Novozymes As SUBTILASE ENZYME DER I-S1 UND I-S2 UNTERGRUPPEN MIT MINDESTENS EINER ZUSäTZLICHEN AMINOSäURE ZWISCHEN POSITION 132 UND 133
ATE408679T1 (de) 1999-05-20 2008-10-15 Novozymes As Subtilase enzyme der i-s1 und i-s2 untergruppen mit mindestens einer zusätzlichen aminosäure zwischen position 127 und 128
ATE408678T1 (de) 1999-05-20 2008-10-15 Novozymes As Subtilase enzyme der i-s1 und i-s2 untergruppen mit mindestens einer zusätzlichen aminosäure zwischen position 129 und 130
DE60039693D1 (de) 1999-05-20 2008-09-11 Novozymes As Subtilase-enzyme der i-s1 und i-s2 untergruppen mit wenigstens einem zusätzlichen aminosäurerest zwischen positionen 125 und 126
EP1183342B2 (fr) 1999-05-20 2012-06-13 Novozymes A/S Enzymes subtilases des -sous groupes i-s1 et i-s2 possedant au moins un residu acide amine supplementaire entre les positions 128 et 129
DE60040149D1 (de) 1999-05-20 2008-10-16 Novozymes As Subtilase-enzyme der i-s1 und i-s2 untergruppen mit wenigstens einem zusätzlichen aminosäurerest zwischen positionen 126 und 127
KR20020021395A (ko) 1999-07-22 2002-03-20 데이비드 엠 모이어 입체적으로 보호된 clip 부위를 갖는 프로테아제콘쥬게이트
BR0012693A (pt) 1999-07-22 2002-04-09 Procter & Gamble Variante, de protease tipo subtilisina; composição de limpeza; e composição de cuidado pessoal
US6946128B1 (en) 1999-07-22 2005-09-20 The Procter & Gamble Company Protease conjugates having sterically protected epitope regions
EP1210415A2 (fr) 1999-07-22 2002-06-05 The Procter & Gamble Company Proteases variantes de la subtilisine par substitutions acide amine dans des regions definies de l'epitope
US6558939B1 (en) 1999-08-31 2003-05-06 Novozymes, A/S Proteases and variants thereof
US7217554B2 (en) 1999-08-31 2007-05-15 Novozymes A/S Proteases and variants thereof
NZ517409A (en) 1999-08-31 2004-05-28 Novozymes As RP-II properties with amino acid substitutions used in detergent compositions and additives
BR9917481A (pt) * 1999-09-09 2002-05-21 Procter & Gamble Composição detergente contendo uma protease
WO2001021499A1 (fr) 1999-09-22 2001-03-29 The Procter & Gamble Company Recipient portatif pour liquides
ES2348461T3 (es) 1999-10-15 2010-12-07 Danisco Us Inc. Gránulos que contienen proteínas y formulaciones de gránulos.
US6727085B2 (en) * 1999-12-15 2004-04-27 Fanoe Tina Sejersgaard Subtilase variants having an improved wash performance on egg stains
US6960462B2 (en) 2000-02-08 2005-11-01 Dsm Ip Assets B.V Use of acid-stable subtilisin proteases in animal feed
US6855548B2 (en) 2000-02-08 2005-02-15 F. Hoffman-La Roche Ag Use of acid-stable proteases in animal feed
US6777218B1 (en) 2000-03-14 2004-08-17 Novozymes A/S Subtilase enzymes having an improved wash performance on egg stains
AU2002211811A1 (en) 2000-10-27 2002-05-06 Genencor International, Inc. Particle with substituted polyvinyl alcohol coating
US6803222B2 (en) * 2000-11-22 2004-10-12 Kao Corporation Alkaline proteases
DK1373296T3 (da) 2001-03-23 2012-01-09 Procter & Gamble Proteiner, der frembringer et ændret immunogent respons, og fremgangsmåder til fremstilling og anvendelse deraf
US8076113B2 (en) 2001-04-02 2011-12-13 Danisco Us Inc. Method for producing granules with reduced dust potential comprising an antifoam agent
US7157416B2 (en) 2001-07-20 2007-01-02 Genencor International, Inc. Stabilization of enzymes
US7153820B2 (en) 2001-08-13 2006-12-26 Ecolab Inc. Solid detergent composition and method for solidifying a detergent composition
DE10163884A1 (de) 2001-12-22 2003-07-10 Henkel Kgaa Neue Alkalische Protease aus Bacillus sp. (DSM 14392) und Wasch- und Reinigungsmittel enthaltend diese neue Alkalische Protease
CA2795814A1 (fr) 2001-12-31 2003-07-17 Genencor International, Inc. Proteases produisant une reponse immunogene modifiee et leurs procedes de production et d'utilisation
AU2002353178C1 (en) * 2001-12-31 2011-02-03 Genencor International, Inc. Proteases producing an altered immunological response and methods of making and using the same
EP2339017A3 (fr) 2002-03-29 2011-10-12 Genencor International, Inc. Expression de protéines augmentée dans Bacillus
CA2502304C (fr) 2002-10-08 2013-10-01 Genencor International, Inc. Peptides de liaison phenoliques
US7888093B2 (en) * 2002-11-06 2011-02-15 Novozymes A/S Subtilase variants
DK1594963T3 (da) 2003-02-07 2007-11-26 Novozymes As Proteaser
ATE407202T1 (de) 2003-05-07 2008-09-15 Novozymes As Enzymvarianten von subtilisin (subtilasen)
ATE491788T1 (de) 2003-10-10 2011-01-15 Novozymes As Proteasevarianten
JP4880469B2 (ja) 2003-10-23 2012-02-22 ノボザイムス アクティーゼルスカブ 洗剤中で改良された安定性を有するプロテアーゼ
EP1751264B2 (fr) 2004-05-17 2013-08-28 The Procter and Gamble Company Composition de blanchiment comprenant une oxydase de carbohydrate
US8357408B2 (en) 2004-06-21 2013-01-22 Novozymes A/S Proteases
JP4681283B2 (ja) 2004-11-18 2011-05-11 独立行政法人海洋研究開発機構 新規な高アルカリプロテアーゼ及びその利用
JP4485341B2 (ja) 2004-12-20 2010-06-23 花王株式会社 組換え微生物
EP1700907A1 (fr) 2005-03-11 2006-09-13 Unilever N.V. Composition liquide de blanchiment
EP1700904A1 (fr) 2005-03-11 2006-09-13 Unilever N.V. Composition detergente liquide
US7666963B2 (en) 2005-07-21 2010-02-23 Akzo Nobel N.V. Hybrid copolymers
US9321873B2 (en) 2005-07-21 2016-04-26 Akzo Nobel N.V. Hybrid copolymer compositions for personal care applications
US20100029538A1 (en) 2006-04-14 2010-02-04 Anna-Liisa Auterinen One-Step Treatment of Textiles
EP2013339B1 (fr) 2006-04-20 2013-09-11 Novozymes A/S Variants de savinase offrant une meilleure efficacité de lavage contre les taches d'oeuf
US20080020961A1 (en) 2006-07-21 2008-01-24 Rodrigues Klin A Low Molecular Weight Graft Copolymers
US8674021B2 (en) 2006-07-21 2014-03-18 Akzo Nobel N.V. Sulfonated graft copolymers
US8093200B2 (en) 2007-02-15 2012-01-10 Ecolab Usa Inc. Fast dissolving solid detergent
US20100190682A1 (en) 2007-04-30 2010-07-29 Sang-Kyu Lee Use of protein hydrolysates to stabilize metalloprotease detergent formulations
SG148934A1 (en) 2007-06-11 2009-01-29 Novozymes As A process for combined biopolishing and bleach clean-up
US8383589B2 (en) 2007-07-09 2013-02-26 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Aegyptin and uses thereof
MX2010003721A (es) 2007-10-18 2010-05-17 Ecolab Inc Composiciones limpiadoras solidas, cerosas, comprimidas y metodos para elaborarlas.
MX2010004372A (es) * 2007-10-31 2010-05-20 Danisco Us Inc Uso y elaboracion de metaloproteasas neutras estables en citrato.
BRPI0908237A2 (pt) 2008-02-14 2015-07-21 Danisco Us Inc Pequenos grânulos contendo enzima
US8153574B2 (en) 2009-03-18 2012-04-10 The Procter & Gamble Company Structured fluid detergent compositions comprising dibenzylidene polyol acetal derivatives and detersive enzymes
US8293697B2 (en) 2009-03-18 2012-10-23 The Procter & Gamble Company Structured fluid detergent compositions comprising dibenzylidene sorbitol acetal derivatives
EP2435547A1 (fr) 2009-05-26 2012-04-04 The Procter & Gamble Company Composition liquide aqueuse pour un prétraitement de vaisselle souillée
DE102009027045A1 (de) * 2009-06-19 2010-12-30 Henkel Ag & Co. Kgaa Neue Proteasen und Mittel enthaltend diese Proteasen
US20110009307A1 (en) 2009-07-09 2011-01-13 Alan Thomas Brooker Laundry Detergent Composition Comprising Low Level of Sulphate
WO2011005623A1 (fr) 2009-07-09 2011-01-13 The Procter & Gamble Company Composition détergente pour lessive comprenant de faibles taux d'agent de blanchiment
JP5882991B2 (ja) 2010-05-14 2016-03-09 ザ サン プロダクツ コーポレーション ポリマー含有洗浄組成物ならびにその生成法および使用法
CN103154263A (zh) * 2010-08-19 2013-06-12 诺维信公司 诱导的孢子形成筛选方法
AU2012260576B2 (en) 2011-05-20 2015-07-09 Ecolab Usa Inc. Acid formulations for use in a system for warewashing
AU2012260575B2 (en) 2011-05-20 2015-09-03 Ecolab Usa Inc. Non-phosphate detergents and non-phosphoric acids in an alternating alkali/acid system for warewashing
US8841246B2 (en) 2011-08-05 2014-09-23 Ecolab Usa Inc. Cleaning composition containing a polysaccharide hybrid polymer composition and methods of improving drainage
US8853144B2 (en) 2011-08-05 2014-10-07 Ecolab Usa Inc. Cleaning composition containing a polysaccharide graft polymer composition and methods of improving drainage
US8679366B2 (en) 2011-08-05 2014-03-25 Ecolab Usa Inc. Cleaning composition containing a polysaccharide graft polymer composition and methods of controlling hard water scale
US8636918B2 (en) 2011-08-05 2014-01-28 Ecolab Usa Inc. Cleaning composition containing a polysaccharide hybrid polymer composition and methods of controlling hard water scale
CN103889395A (zh) 2011-11-04 2014-06-25 阿克佐诺贝尔化学国际公司 接枝树枝状共聚物及其制备方法
IN2014DN03123A (fr) 2011-11-04 2015-05-22 Akzo Nobel Chemicals Int Bv
ES2643844T3 (es) 2011-12-13 2017-11-24 Ecolab Usa Inc. Composiciones concentradas de lavado de vajilla y métodos
WO2014007229A1 (fr) * 2012-07-06 2014-01-09 東洋紡株式会社 Alcaline phosphatase modifiée
CA2879352A1 (fr) 2012-07-26 2014-01-30 The Procter & Gamble Company Compositions de nettoyage liquides a faible ph et a enzymes
US8945314B2 (en) 2012-07-30 2015-02-03 Ecolab Usa Inc. Biodegradable stability binding agent for a solid detergent
US9745543B2 (en) 2012-09-10 2017-08-29 Ecolab Usa Inc. Stable liquid manual dishwashing compositions containing enzymes
EP2904085B1 (fr) 2012-10-04 2018-11-07 Ecolab USA Inc. Technologie de prétrempage pour blanchissage et autre nettoyage de surfaces dures
US9139458B2 (en) 2013-03-15 2015-09-22 Janet Angel Compositions and methods of use
EP3044301B1 (fr) 2013-09-09 2017-10-25 Ecolab USA Inc. Élimination synergique de taches par le biais d'une nouvelle combinaison de chélateurs
EP3279304B1 (fr) 2013-09-09 2019-06-05 Ecolab USA Inc. Élimination synergique de taches par le biais d'une nouvelle combinaison de chélateurs
JP6254693B2 (ja) 2013-10-24 2017-12-27 エコラボ ユーエスエー インコーポレイティド 表面から汚れを除去する組成物及び方法
US9365805B2 (en) 2014-05-15 2016-06-14 Ecolab Usa Inc. Bio-based pot and pan pre-soak
CN106793912A (zh) 2014-08-01 2017-05-31 艺康美国股份有限公司 使用清洁织物的人工表面清洁和洗涤所述清洁织物的方法
US10577571B2 (en) 2016-11-08 2020-03-03 Ecolab Usa Inc. Non-aqueous cleaner for vegetable oil soils
WO2020099491A1 (fr) 2018-11-14 2020-05-22 Novozymes A/S Composition de soin buccal comprenant un polypeptide ayant une activité dnase
US11891588B2 (en) 2019-07-31 2024-02-06 Ecolab Usa Inc. Personal protective equipment free delimer compositions o
US11873465B2 (en) 2019-08-14 2024-01-16 Ecolab Usa Inc. Methods of cleaning and soil release of highly oil absorbing substrates employing optimized extended chain nonionic surfactants
CN110760466B (zh) * 2019-11-18 2021-04-20 山东隆科特酶制剂有限公司 一株产耐高温中性蛋白酶的枯草芽孢杆菌及其应用
CN116075583A (zh) 2020-07-06 2023-05-05 埃科莱布美国股份有限公司 包含烷基硅氧烷和水溶助剂/增溶剂的组合的发泡混合醇/水组合物
WO2022010906A1 (fr) 2020-07-06 2022-01-13 Ecolab Usa Inc. Compositions à base d'huile de ricin modifiée par peg pour la microémulsification et l'élimination de multiples salissures grasses
WO2022010911A1 (fr) 2020-07-06 2022-01-13 Ecolab Usa Inc. Compositions d'alcool/eau mixtes moussantes comprenant un siloxane alcoxylé structuré
KR20230057391A (ko) 2020-08-24 2023-04-28 노보자임스 에이/에스 프럭타나제를 포함하는 구강 관리 조성물
US20240247209A1 (en) 2021-05-18 2024-07-25 Nouryon Chemicals International B.V. Polyester polyquats in cleaning applications
WO2022243533A1 (fr) 2021-05-20 2022-11-24 Nouryon Chemicals International B.V. Polymères fabriqués présentant une fonctionnalité d'oligosaccharide ou de polysaccharide modifiée ou une distribution rétrécie d'oligosaccharides, procédés pour leur préparation, compositions les contenant et procédés pour leur utilisation
EP4363541A1 (fr) 2021-06-30 2024-05-08 Nouryon Chemicals International B.V. Concentrés liquides tensioactifs amphotères de chélates et leur utilisation dans des applications de nettoyage
WO2023057367A1 (fr) 2021-10-08 2023-04-13 Unilever Ip Holdings B.V. Composition de lessive
US20240026248A1 (en) 2022-07-20 2024-01-25 Ecolab Usa Inc. Novel nonionic extended surfactants, compositions and methods of use thereof

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US362957A (en) * 1887-05-17 haig-ht
US3557002A (en) * 1967-11-15 1971-01-19 Procter & Gamble Stabilized aqueous enzyme preparation
US3558498A (en) 1967-11-29 1971-01-26 Procter & Gamble Granular detergent composition containing enzymes and environmental control components
GB1240058A (en) * 1968-04-12 1971-07-21 Procter & Gamble Enzyme-containing detergent compositions
US3623957A (en) 1970-01-21 1971-11-30 Baxter Laboratories Inc Preparation of microbial alkaline protease by fermentation with bacillus subtilis, variety licheniformis
BE785666A (fr) 1971-07-01 1973-01-02 Procter & Gamble Procede pour la production de compositions enzymatiques en granules
BE792982A (en) 1971-12-20 1973-06-19 Procter & Gamble Europ Proteolytic enzymes detergent - contg cationic and anionic surfactants
US4011169A (en) 1973-06-29 1977-03-08 The Procter & Gamble Company Stabilization and enhancement of enzymatic activity
DE2709476A1 (de) 1976-03-08 1977-09-15 Procter & Gamble Europ Fluessiges, enzymhaltiges wasch- und reinigungsmittel
US4090973A (en) 1976-06-24 1978-05-23 The Procter & Gamble Company Method for making stable detergent compositions
DE2633601A1 (de) 1976-07-27 1978-02-02 Henkel Kgaa Fluessiges, als wasch- und reinigungsmittel verwendbares, enzymhaltiges konzentrat
GB1603640A (en) 1977-07-20 1981-11-25 Gist Brocades Nv Enzyme particles
US4261868A (en) 1979-08-08 1981-04-14 Lever Brothers Company Stabilized enzymatic liquid detergent composition containing a polyalkanolamine and a boron compound
US4302544A (en) * 1979-10-15 1981-11-24 University Of Rochester Asporogenous mutant of B. subtilis for use as host component of HV1 system
US4318818A (en) 1979-11-09 1982-03-09 The Procter & Gamble Company Stabilized aqueous enzyme composition
JPS5950280B2 (ja) 1980-10-24 1984-12-07 花王株式会社 酵素入り漂白剤組成物
JPS5786299A (en) * 1980-11-19 1982-05-29 Dai Ichi Seiyaku Co Ltd Plasmid and its preparation
IE52434B1 (en) * 1981-01-15 1987-10-28 Cpc International Inc A process for cloning the gene coding for a thermostable alpha-amylase into escherichia coli and bacillus subtilis
US4404128A (en) 1981-05-29 1983-09-13 The Procter & Gamble Company Enzyme detergent composition
DE3122216A1 (de) * 1981-06-04 1982-12-23 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur herstellung eines mikroorganismus, welcher (alpha)-galactosidase, aber keine invertase bildet, so erhaltener mikroorganismus und seine verwendung
DE3264685D1 (en) 1981-11-13 1985-08-14 Unilever Nv Enzymatic liquid cleaning composition
JPS58162291A (ja) * 1982-03-23 1983-09-26 Res Dev Corp Of Japan 耐熱性プロテア−ゼの製造法
GR78180B (fr) * 1982-04-15 1984-09-26 Genentech Inc
JPS5959190A (ja) * 1982-09-29 1984-04-04 Agency Of Ind Science & Technol プロテア−ゼの製造法
DK135983D0 (da) * 1983-03-25 1983-03-25 Novo Industri As Maltogen amylaseenzymprodukt og fremgangsmade til dets fremstilling og anvendelse
NZ208612A (en) 1983-06-24 1991-09-25 Genentech Inc Method of producing "procaryotic carbonyl hydrolases" containing predetermined, site specific mutations

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EP0246678B1 (fr) 1993-04-28
EP0247647B1 (fr) 1991-01-23
DE3486139T2 (de) 1993-11-11
DK175278B1 (da) 2004-08-02
DE3484019D1 (de) 1991-02-28
HK75393A (en) 1993-08-06
NZ208612A (en) 1991-09-25
DK305984D0 (da) 1984-06-22
EP0247647A1 (fr) 1987-12-02
JP2594533B2 (ja) 1997-03-26
EP0130756B1 (fr) 1991-02-06
JPH06315378A (ja) 1994-11-15
JP2889095B2 (ja) 1999-05-10
DE3486139D1 (fr) 1993-06-03
IE841567L (en) 1984-12-24
DK82293A (da) 1993-07-08
DK82293D0 (da) 1993-07-08
IE81141B1 (en) 2000-04-05
ATE60356T1 (de) 1991-02-15
EP0130756A1 (fr) 1985-01-09
JPH06319534A (ja) 1994-11-22
DK82393A (da) 1993-07-08
EP0246678A1 (fr) 1987-11-25
EP0130756B2 (fr) 2000-06-28
DE3484079D1 (de) 1991-03-14
DK305984A (da) 1985-02-18
JPS6070075A (ja) 1985-04-20
HK99293A (en) 1993-09-30
DK82393D0 (da) 1993-07-08
EP0357157A2 (fr) 1990-03-07
DK175768B1 (da) 2005-02-14
ATE60797T1 (de) 1991-02-15
EP0357157A3 (fr) 1990-03-28

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