HK60585A - 2,6-dimethyl-4-(2,3-dichlorophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid-3-methyl ester-5-ethyl ester having hypotensive properties,process for its preparation and pharmaceutical preparations containing it - Google Patents

2,6-dimethyl-4-(2,3-dichlorophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid-3-methyl ester-5-ethyl ester having hypotensive properties,process for its preparation and pharmaceutical preparations containing it

Info

Publication number
HK60585A
HK60585A HK605/85A HK60585A HK60585A HK 60585 A HK60585 A HK 60585A HK 605/85 A HK605/85 A HK 605/85A HK 60585 A HK60585 A HK 60585A HK 60585 A HK60585 A HK 60585A
Authority
HK
Hong Kong
Prior art keywords
sub
preparation
dihydropyridine
dichlorophenyl
pharmaceutical preparations
Prior art date
Application number
HK605/85A
Other languages
English (en)
Inventor
Peter Bernhard Berntsson
Stig Ake Ingemar Carlsson
Jan Oernulf Gaarder
Bengt Richard Ljung
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20335348&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK60585(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Haessle Ab filed Critical Haessle Ab
Publication of HK60585A publication Critical patent/HK60585A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK605/85A 1978-06-30 1985-08-15 2,6-dimethyl-4-(2,3-dichlorophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid-3-methyl ester-5-ethyl ester having hypotensive properties,process for its preparation and pharmaceutical preparations containing it HK60585A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7807404A SE429652B (sv) 1978-06-30 1978-06-30 2.6-dimetyl-4-(2.3-diklorfenyl)-1.4-dihydropyridin-3.5-dikarboxylsyra-3-metylester-5-etylester

Publications (1)

Publication Number Publication Date
HK60585A true HK60585A (en) 1985-08-23

Family

ID=20335348

Family Applications (1)

Application Number Title Priority Date Filing Date
HK605/85A HK60585A (en) 1978-06-30 1985-08-15 2,6-dimethyl-4-(2,3-dichlorophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid-3-methyl ester-5-ethyl ester having hypotensive properties,process for its preparation and pharmaceutical preparations containing it

Country Status (24)

Country Link
US (1) US4264611A (ko)
EP (1) EP0007293B1 (ko)
JP (1) JPS559083A (ko)
AT (1) ATE1237T1 (ko)
AU (1) AU529116B2 (ko)
BG (1) BG61420B2 (ko)
CA (1) CA1117530A (ko)
CS (1) CS241021B2 (ko)
CY (1) CY1299A (ko)
DD (1) DD144667A5 (ko)
DE (1) DE2963150D1 (ko)
DK (1) DK148978C (ko)
FI (1) FI70573C (ko)
HK (1) HK60585A (ko)
HU (1) HU178568B (ko)
IE (1) IE48650B1 (ko)
LU (2) LU88666I2 (ko)
NL (2) NL930054I2 (ko)
NO (3) NO151965C (ko)
NZ (1) NZ190809A (ko)
SE (1) SE429652B (ko)
SG (1) SG26085G (ko)
SU (2) SU856380A3 (ko)
ZA (1) ZA792804B (ko)

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JP5498168B2 (ja) 2006-12-01 2014-05-21 ブリストル−マイヤーズ スクイブ カンパニー アテローム性動脈硬化および循環器疾患の治療のためのｃｅｔｐ阻害剤としてのｎ−（（３−ベンジル）−２，２−（ビス−フェニル）−プロパン−１−アミン誘導体
US8748648B2 (en) * 2007-09-06 2014-06-10 Nektar Therapeutics Oligomer-calcium channel blocker conjugates
EP2211906A2 (en) * 2007-11-07 2010-08-04 Janssen Pharmaceutica, N.V. Combination therapy comprising angiotensin converting enzyme inhibitors and vasopressin receptor antagonists
WO2012037665A1 (en) 2010-09-24 2012-03-29 Oral Delivery Technology Ltd. Nitric oxide releasing amino acid ester for treatment of pulmonary hypertension and other respiratory conditions
WO2012123966A1 (en) 2011-03-04 2012-09-20 Arch Pharmalabs Limited Process for the preparation of 4 -substituted -1, 4-dihydropyridines
CN102827068A (zh) * 2011-06-17 2012-12-19 张锐豪 一种4-(2, 3-二氯苯基)-2, 6-二甲基-1, 4-二氢-5-甲氧基羰基-3-吡啶羧酸的制备方法
CN103906508A (zh) 2011-08-26 2014-07-02 沃克哈特有限公司 治疗心血管疾病的方法
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CN104177286A (zh) * 2014-08-11 2014-12-03 广东东阳光药业有限公司 一种地平类药物的制备方法
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CN107952483B (zh) * 2017-12-18 2020-07-28 万华化学集团股份有限公司 一种催化剂，使用该催化剂的反应器，以及一种制备β-苯乙醇的方法
CN108840819B (zh) * 2018-04-02 2021-07-30 常州瑞明药业有限公司 一种非洛地平的制备方法
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Also Published As

Publication number Publication date
DE2963150D1 (en) 1982-08-12
ZA792804B (en) 1980-06-25
NL930054I2 (nl) 1994-02-16
JPS6121550B2 (ko) 1986-05-27
NO151965C (no) 1985-07-10
DK275079A (da) 1979-12-31
FI70573B (fi) 1986-06-06
SE7807404L (sv) 1979-12-31
NL940012I1 (nl) 1994-08-01
NZ190809A (en) 1982-03-09
HU178568B (en) 1982-05-28
SG26085G (en) 1986-01-24
IE791217L (en) 1979-12-30
DK148978C (da) 1986-08-18
DK148978B (da) 1985-12-09
FI792058A (fi) 1979-12-31
SU856380A3 (ru) 1981-08-15
AU4831679A (en) 1980-02-07
SE429652B (sv) 1983-09-19
IE48650B1 (en) 1985-04-03
NO1994026I1 (no) 1994-12-21
US4264611B1 (ko) 1984-07-17
LU88666I2 (fr) 1996-02-01
EP0007293A1 (en) 1980-01-23
NL930054I1 (nl) 1993-09-01
ATE1237T1 (de) 1982-07-15
SU915799A3 (en) 1982-03-23
NO1996006I1 (no) 1996-06-24
CY1299A (en) 1985-10-18
DD144667A5 (de) 1980-10-29
AU529116B2 (en) 1983-05-26
JPS559083A (en) 1980-01-22
CA1117530A (en) 1982-02-02
NO151965B (no) 1985-04-01
NO792112L (no) 1980-01-03
EP0007293B1 (en) 1982-06-23
LU88306I2 (fr) 1994-05-04
BG61420B2 (bg) 1997-07-31
CS241021B2 (en) 1986-03-13
US4264611A (en) 1981-04-28
FI70573C (fi) 1986-09-24

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