NO151965B - Analogifremgangsmaate til fremstilling av terapeutisk aktiv 2,6-dimetyl-4-(2,3-diklorfenyl)-1,4-dihydropyridin-3,5-dikarboksylsyre-3-metylester-5-etylester - Google Patents

Analogifremgangsmaate til fremstilling av terapeutisk aktiv 2,6-dimetyl-4-(2,3-diklorfenyl)-1,4-dihydropyridin-3,5-dikarboksylsyre-3-metylester-5-etylester Download PDF

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Publication number
NO151965B
NO151965B NO792112A NO792112A NO151965B NO 151965 B NO151965 B NO 151965B NO 792112 A NO792112 A NO 792112A NO 792112 A NO792112 A NO 792112A NO 151965 B NO151965 B NO 151965B
Authority
NO
Norway
Prior art keywords
sub
crowbar
preparation
dichlorphenyl
dihydropyridine
Prior art date
Application number
NO792112A
Other languages
English (en)
Other versions
NO792112L (no
NO151965C (no
Inventor
Peder Bernard Berntsson
Stig Aake Ingemar Carlsson
Jan Oernulf Gaarder
Bengt Richard Ljung
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20335348&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO151965(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Haessle Ab filed Critical Haessle Ab
Publication of NO792112L publication Critical patent/NO792112L/no
Publication of NO151965B publication Critical patent/NO151965B/no
Publication of NO151965C publication Critical patent/NO151965C/no

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)

Description

Sammenleggbart brekkjern.
Oppfinnelsen angår et sammenleggbart brekkjern.
Det nye ved oppfinnelsen er at
brekkjernet består av to sammenhengs-lede deler som i brekkjernets utfoldede stilling holdes på plass ved hjelp
av en hylseformet del som kan skyves på
plass over hengselforbindelsen og hvor en
skrue festet i den ene hylsedel samvirker
med et leie for den ene brekkjerndel på
en slik måte at delene låses sammen til
en stiv forbindelse.
Oppfinnelsen er vist på tegningen, der
figur 1 viser, delvis i snitt, brekkjernet
ferdig til bruk og
figur 2 viser et snitt etter linjen II—
II i figur 1.
Brekkjernet består av de to deler 1 og
2 som er hengslet sammen ved at delen 1
i den ene ende er utstyrt med en gaffel-formet del bestående av to gaffeldeler 3,
mens delen 2 har en avflatet del 4 som
passer inn mellom delene 3 og her holdes
på plass ved hjelp av en nagle e. 1. 5.
En hylsedel 6, 7 er satt sammen av
to rørformete deler 6 og 7, for eksempel
ved sveising. Delen 7 passer med minst
mulig klaring omkring brekkjernhalvdelen
2. Delen 8 har noe større diameter for å
kunne passe omkring den gaffelformede
del 3—3 på brekkjernhalvdelen 1. Som det
fremgår av tegningens figur 1 er gaffel-delen utført med en viss krumning for at
de to brekkjernhalvdeler skal kunne foldes
helt sammen. Hylsedelen 6 er i den ende
hvor den er sammensveiset med hylsedelen 7 lukket med en sigdformet del 8 som dek-ker det parti av delen 6 som rager utenfor delen 7.
Hylsedelen 6 har videre et tilformet leie 9 som brekkjernhalvdelen 1 presses mot ved hjelp av skruen 10 som løper i gjengen i en forsterkningsdel 11 på hylsedelen 6.
I sammenlagt stilling av brekkjernet er skruen 10 skrudd helt opp og hylsedelen skjøvet over til venstre på figur 1. Brekkjernhalvdelen 1 kan da svinges over slik at den legger seg parallelt med delen 2. Hylsedelen 6—7 må herunder vris noe slik at delen 1 ikke legger seg an mot den opprakende skrue 10.
Når brekkjernet er sammenlagt vil det lett få plass i en vanlig verktøyveske.

Claims (1)

  1. Sammenleggbart brekkjern, karakterisert ved at det består av to sam-menhengslede deler (1, 2) som i brekkjernets utfoldede stilling holdes på plass ved hjelp av en hylseformet del (6, 7) som kan skyves på plass over hengselforbindelsen (3, 4, 5) og hvor en skrue (10) festet i den ene hylsedel (6) samvirker med et leie (9) for den ene brekkjerndel (1) på en slik måte at delene låses sammen til en stiv forbindelse.
NO792112A 1978-06-30 1979-06-22 Analogifremgangsmaate til fremstilling av terapeutisk aktiv 2,6-dimetyl-4-(2,3-diklorfenyl)-1,4-dihydropyridin-3,5-dikarboksylsyre-3-metylester-5-etylester NO151965C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7807404A SE429652B (sv) 1978-06-30 1978-06-30 2.6-dimetyl-4-(2.3-diklorfenyl)-1.4-dihydropyridin-3.5-dikarboxylsyra-3-metylester-5-etylester

Publications (3)

Publication Number Publication Date
NO792112L NO792112L (no) 1980-01-03
NO151965B true NO151965B (no) 1985-04-01
NO151965C NO151965C (no) 1985-07-10

Family

ID=20335348

Family Applications (3)

Application Number Title Priority Date Filing Date
NO792112A NO151965C (no) 1978-06-30 1979-06-22 Analogifremgangsmaate til fremstilling av terapeutisk aktiv 2,6-dimetyl-4-(2,3-diklorfenyl)-1,4-dihydropyridin-3,5-dikarboksylsyre-3-metylester-5-etylester
NO1994026C NO1994026I1 (no) 1978-06-30 1994-12-21 Pledil/Felodipin/ 2,6-dimetyl-4-(2,3-diklorfenyl)-1,4-dihydropyridin-3,5-dikarboksylsyre-3-metylester-5-etylester
NO1996006C NO1996006I1 (no) 1978-06-30 1996-06-24 Felodipine

Family Applications After (2)

Application Number Title Priority Date Filing Date
NO1994026C NO1994026I1 (no) 1978-06-30 1994-12-21 Pledil/Felodipin/ 2,6-dimetyl-4-(2,3-diklorfenyl)-1,4-dihydropyridin-3,5-dikarboksylsyre-3-metylester-5-etylester
NO1996006C NO1996006I1 (no) 1978-06-30 1996-06-24 Felodipine

Country Status (24)

Country Link
US (1) US4264611A (no)
EP (1) EP0007293B1 (no)
JP (1) JPS559083A (no)
AT (1) ATE1237T1 (no)
AU (1) AU529116B2 (no)
BG (1) BG61420B2 (no)
CA (1) CA1117530A (no)
CS (1) CS241021B2 (no)
CY (1) CY1299A (no)
DD (1) DD144667A5 (no)
DE (1) DE2963150D1 (no)
DK (1) DK148978C (no)
FI (1) FI70573C (no)
HK (1) HK60585A (no)
HU (1) HU178568B (no)
IE (1) IE48650B1 (no)
LU (2) LU88666I2 (no)
NL (2) NL930054I2 (no)
NO (3) NO151965C (no)
NZ (1) NZ190809A (no)
SE (1) SE429652B (no)
SG (1) SG26085G (no)
SU (2) SU856380A3 (no)
ZA (1) ZA792804B (no)

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Also Published As

Publication number Publication date
SU915799A3 (en) 1982-03-23
IE791217L (en) 1979-12-30
NO792112L (no) 1980-01-03
NZ190809A (en) 1982-03-09
JPS6121550B2 (no) 1986-05-27
AU529116B2 (en) 1983-05-26
SG26085G (en) 1986-01-24
ZA792804B (en) 1980-06-25
NO1994026I1 (no) 1994-12-21
EP0007293B1 (en) 1982-06-23
FI70573B (fi) 1986-06-06
AU4831679A (en) 1980-02-07
DD144667A5 (de) 1980-10-29
FI70573C (fi) 1986-09-24
NL930054I1 (nl) 1993-09-01
HK60585A (en) 1985-08-23
ATE1237T1 (de) 1982-07-15
NL930054I2 (nl) 1994-02-16
SE7807404L (sv) 1979-12-31
CA1117530A (en) 1982-02-02
HU178568B (en) 1982-05-28
DE2963150D1 (en) 1982-08-12
SU856380A3 (ru) 1981-08-15
LU88666I2 (fr) 1996-02-01
US4264611B1 (no) 1984-07-17
US4264611A (en) 1981-04-28
DK148978B (da) 1985-12-09
EP0007293A1 (en) 1980-01-23
DK148978C (da) 1986-08-18
NL940012I1 (nl) 1994-08-01
SE429652B (sv) 1983-09-19
IE48650B1 (en) 1985-04-03
LU88306I2 (fr) 1994-05-04
NO1996006I1 (no) 1996-06-24
BG61420B2 (bg) 1997-07-31
CY1299A (en) 1985-10-18
CS241021B2 (en) 1986-03-13
JPS559083A (en) 1980-01-22
NO151965C (no) 1985-07-10
FI792058A (fi) 1979-12-31
DK275079A (da) 1979-12-31

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