CY1299A - New 2,6-dimethyl-4,2,3-disubstituted phenyl-1,4-dihydropyridine-3,5-dicarboxylic acid-3,5-asymmetric diesters having hypotensive properties,as well as process for their preparation and pharmaceutical preparation containing same - Google Patents

New 2,6-dimethyl-4,2,3-disubstituted phenyl-1,4-dihydropyridine-3,5-dicarboxylic acid-3,5-asymmetric diesters having hypotensive properties,as well as process for their preparation and pharmaceutical preparation containing same

Info

Publication number
CY1299A
CY1299A CY1299A CY129979A CY1299A CY 1299 A CY1299 A CY 1299A CY 1299 A CY1299 A CY 1299A CY 129979 A CY129979 A CY 129979A CY 1299 A CY1299 A CY 1299A
Authority
CY
Cyprus
Prior art keywords
sub
dihydropyridine
dimethyl
new
well
Prior art date
Application number
CY1299A
Other languages
English (en)
Inventor
Peter Bernhard Berntsson
Stig Ake Ingemar Carlsson
Jan Oernulf Gaarder
Bengt Richard Ljung
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20335348&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1299(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Haessle Ab filed Critical Haessle Ab
Publication of CY1299A publication Critical patent/CY1299A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
CY1299A 1978-06-30 1979-06-12 New 2,6-dimethyl-4,2,3-disubstituted phenyl-1,4-dihydropyridine-3,5-dicarboxylic acid-3,5-asymmetric diesters having hypotensive properties,as well as process for their preparation and pharmaceutical preparation containing same CY1299A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7807404A SE429652B (sv) 1978-06-30 1978-06-30 2.6-dimetyl-4-(2.3-diklorfenyl)-1.4-dihydropyridin-3.5-dikarboxylsyra-3-metylester-5-etylester

Publications (1)

Publication Number Publication Date
CY1299A true CY1299A (en) 1985-10-18

Family

ID=20335348

Family Applications (1)

Application Number Title Priority Date Filing Date
CY1299A CY1299A (en) 1978-06-30 1979-06-12 New 2,6-dimethyl-4,2,3-disubstituted phenyl-1,4-dihydropyridine-3,5-dicarboxylic acid-3,5-asymmetric diesters having hypotensive properties,as well as process for their preparation and pharmaceutical preparation containing same

Country Status (24)

Country Link
US (1) US4264611A (xx)
EP (1) EP0007293B1 (xx)
JP (1) JPS559083A (xx)
AT (1) ATE1237T1 (xx)
AU (1) AU529116B2 (xx)
BG (1) BG61420B2 (xx)
CA (1) CA1117530A (xx)
CS (1) CS241021B2 (xx)
CY (1) CY1299A (xx)
DD (1) DD144667A5 (xx)
DE (1) DE2963150D1 (xx)
DK (1) DK148978C (xx)
FI (1) FI70573C (xx)
HK (1) HK60585A (xx)
HU (1) HU178568B (xx)
IE (1) IE48650B1 (xx)
LU (2) LU88666I2 (xx)
NL (2) NL930054I2 (xx)
NO (3) NO151965C (xx)
NZ (1) NZ190809A (xx)
SE (1) SE429652B (xx)
SG (1) SG26085G (xx)
SU (2) SU856380A3 (xx)
ZA (1) ZA792804B (xx)

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AU561213B2 (en) * 1983-06-02 1987-04-30 Teijin Limited 1, 4-dihydropyridine derivative
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US6555139B2 (en) 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
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ATE551059T1 (de) * 2005-10-26 2012-04-15 Asahi Kasei Pharma Corp Fasudil in kombination mit bosentan zur behandlung von pulmonaler arterieller hypertonie
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CN102827068A (zh) * 2011-06-17 2012-12-19 张锐豪 一种4-(2, 3-二氯苯基)-2, 6-二甲基-1, 4-二氢-5-甲氧基羰基-3-吡啶羧酸的制备方法
CN103906508A (zh) 2011-08-26 2014-07-02 沃克哈特有限公司 治疗心血管疾病的方法
CN105143203A (zh) 2013-04-17 2015-12-09 辉瑞大药厂 用于治疗心血管疾病的n-哌啶-3-基苯甲酰胺衍生物
CN104177286A (zh) * 2014-08-11 2014-12-03 广东东阳光药业有限公司 一种地平类药物的制备方法
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CN107952483B (zh) * 2017-12-18 2020-07-28 万华化学集团股份有限公司 一种催化剂，使用该催化剂的反应器，以及一种制备β-苯乙醇的方法
CN108840819B (zh) * 2018-04-02 2021-07-30 常州瑞明药业有限公司 一种非洛地平的制备方法
CN112955965B (zh) 2018-06-14 2024-04-09 阿斯利康(英国)有限公司 使用二氢吡啶类钙通道阻断剂医药组合物降低血压的方法
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DE1670824C3 (de) * 1967-03-20 1978-08-03 Bayer Ag, 5090 Leverkusen 1,4-Dihydropyridin-33-dicarbonsäurealkylester
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Also Published As

Publication number Publication date
SU915799A3 (en) 1982-03-23
IE791217L (en) 1979-12-30
NO151965B (no) 1985-04-01
NO792112L (no) 1980-01-03
NZ190809A (en) 1982-03-09
JPS6121550B2 (xx) 1986-05-27
AU529116B2 (en) 1983-05-26
SG26085G (en) 1986-01-24
ZA792804B (en) 1980-06-25
NO1994026I1 (no) 1994-12-21
EP0007293B1 (en) 1982-06-23
FI70573B (fi) 1986-06-06
AU4831679A (en) 1980-02-07
DD144667A5 (de) 1980-10-29
FI70573C (fi) 1986-09-24
NL930054I1 (nl) 1993-09-01
HK60585A (en) 1985-08-23
ATE1237T1 (de) 1982-07-15
NL930054I2 (nl) 1994-02-16
SE7807404L (sv) 1979-12-31
CA1117530A (en) 1982-02-02
HU178568B (en) 1982-05-28
DE2963150D1 (en) 1982-08-12
SU856380A3 (ru) 1981-08-15
LU88666I2 (fr) 1996-02-01
US4264611B1 (xx) 1984-07-17
US4264611A (en) 1981-04-28
DK148978B (da) 1985-12-09
EP0007293A1 (en) 1980-01-23
DK148978C (da) 1986-08-18
NL940012I1 (nl) 1994-08-01
SE429652B (sv) 1983-09-19
IE48650B1 (en) 1985-04-03
LU88306I2 (fr) 1994-05-04
NO1996006I1 (no) 1996-06-24
BG61420B2 (bg) 1997-07-31
CS241021B2 (en) 1986-03-13
JPS559083A (en) 1980-01-22
NO151965C (no) 1985-07-10
FI792058A (fi) 1979-12-31
DK275079A (da) 1979-12-31

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