HK123694A - (1H-imidazol-1-ylmethyl) substituted benzimidazole derivatives - Google Patents

(1H-imidazol-1-ylmethyl) substituted benzimidazole derivatives Download PDF

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Publication number
HK123694A
HK123694A HK123694A HK123694A HK123694A HK 123694 A HK123694 A HK 123694A HK 123694 A HK123694 A HK 123694A HK 123694 A HK123694 A HK 123694A HK 123694 A HK123694 A HK 123694A
Authority
HK
Hong Kong
Prior art keywords
parts
formula
imidazol
compound
alkyl
Prior art date
Application number
HK123694A
Other languages
German (de)
English (en)
French (fr)
Inventor
H. M. Raeymaekers Alfons
J. E. Freyne Eddy
C. Sanz Gerard
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of HK123694A publication Critical patent/HK123694A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK123694A 1986-09-15 1994-11-10 (1H-imidazol-1-ylmethyl) substituted benzimidazole derivatives HK123694A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US90790386A 1986-09-15 1986-09-15

Publications (1)

Publication Number Publication Date
HK123694A true HK123694A (en) 1994-11-18

Family

ID=25424835

Family Applications (1)

Application Number Title Priority Date Filing Date
HK123694A HK123694A (en) 1986-09-15 1994-11-10 (1H-imidazol-1-ylmethyl) substituted benzimidazole derivatives

Country Status (23)

Country Link
EP (1) EP0260744B1 (forum.php)
JP (1) JPS6485975A (forum.php)
KR (1) KR960014353B1 (forum.php)
CN (1) CN1020903C (forum.php)
AU (1) AU595064B2 (forum.php)
BG (1) BG61321B2 (forum.php)
CA (1) CA1323366C (forum.php)
CY (1) CY1803A (forum.php)
DE (1) DE3783107T2 (forum.php)
DK (1) DK174728B1 (forum.php)
ES (1) ES2053524T3 (forum.php)
FI (1) FI87781C (forum.php)
GR (1) GR3006841T3 (forum.php)
HK (1) HK123694A (forum.php)
HU (1) HU198039B (forum.php)
IE (1) IE60514B1 (forum.php)
IL (1) IL83892A (forum.php)
NO (1) NO167202C (forum.php)
NZ (1) NZ221729A (forum.php)
PH (1) PH25022A (forum.php)
PT (1) PT85692B (forum.php)
SU (1) SU1662350A3 (forum.php)
ZA (1) ZA876881B (forum.php)

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FR2663028B1 (fr) * 1990-06-08 1994-10-14 Roussel Uclaf Nouveaux derives de benzimidazole, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
US5216003A (en) * 1992-01-02 1993-06-01 G. D. Searle & Co. Diacid-containing benzimidazole compounds for treatment of neurotoxic injury
WO1995004723A1 (fr) * 1993-08-04 1995-02-16 Yamanouchi Pharmaceutical Co., Ltd. Derive d'imidazolylalkylamine et composition pharmaceutique contenant ledit derive
FI961418A7 (fi) * 1993-09-30 1996-03-29 Yamanouchi Pharmaceutical Co Ltd Atsolijohdannainen ja sen farmaseuttinen seos
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AU688852B2 (en) * 1994-02-18 1998-03-19 Janssen Pharmaceutica N.V. Enantiomerically pure(-)-liarozole
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JPH10510840A (ja) * 1994-12-22 1998-10-20 リガンド・ファーマシューティカルズ・インコーポレイテッド ステロイド受容体モジュレーター化合物および方法
US6696459B1 (en) 1994-12-22 2004-02-24 Ligand Pharmaceuticals Inc. Steroid receptor modulator compounds and methods
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FR2751649B1 (fr) * 1996-07-26 1998-08-28 Adir Nouveaux derives de benzimidazole, de benzoxazole et de benzothiazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
IT1286866B1 (it) * 1996-10-28 1998-07-17 Menarini Farma Ind Composti furano-eterociclici,loro preparazione ed uso come inibitori di aromatasi
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DK1037880T3 (da) 1997-12-11 2004-11-15 Janssen Pharmaceutica Nv Anilider som retinsyremimetika
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US6858598B1 (en) 1998-12-23 2005-02-22 G. D. Searle & Co. Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
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JP2003501418A (ja) * 1999-06-04 2003-01-14 エラン ファーマ インターナショナル，リミティド 細胞死を阻害するための組成物および方法
JP3938689B2 (ja) 2000-03-16 2007-06-27 エフ．ホフマン−ラ ロシュ アーゲー Ｉｐアンタゴニストとしてのカルボン酸誘導体
KR100725442B1 (ko) 2000-11-17 2007-06-07 다케다 야쿠힌 고교 가부시키가이샤 신규 이미다졸 유도체, 이의 제조 방법 및 이의 용도
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WO2002046186A1 (fr) 2000-12-08 2002-06-13 Takeda Chemical Industries, Ltd. Dérivés thiazole substitués porteurs de groupes 3-pyridyl, procédé d'élaboration et leur utilisation
US7405235B2 (en) 2001-05-04 2008-07-29 Paratek Pharmaceuticals, Inc. Transcription factor modulating compounds and methods of use thereof
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EP1452528B1 (en) * 2001-11-16 2008-08-13 Nippon Chemiphar Co., Ltd. Xanthine oxidase inhibitors
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Also Published As

Publication number Publication date
EP0260744A2 (en) 1988-03-23
DK174728B1 (da) 2003-10-06
NO873840L (no) 1988-03-16
CN1020903C (zh) 1993-05-26
CY1803A (en) 1987-09-09
SU1662350A3 (ru) 1991-07-07
HUT45051A (en) 1988-05-30
EP0260744A3 (en) 1989-01-18
JPH0587071B2 (forum.php) 1993-12-15
FI873977A7 (fi) 1988-03-16
IE872487L (en) 1988-03-15
ZA876881B (en) 1989-04-26
NO167202C (no) 1991-10-16
FI87781C (fi) 1993-02-25
KR960014353B1 (ko) 1996-10-15
PT85692B (pt) 1990-06-29
DK479487A (da) 1988-03-16
JPS6485975A (en) 1989-03-30
DE3783107T2 (de) 1993-04-22
EP0260744B1 (en) 1992-12-16
AU7838587A (en) 1988-04-14
PH25022A (en) 1991-01-28
KR880003935A (ko) 1988-06-01
PT85692A (en) 1987-10-01
DE3783107D1 (de) 1993-01-28
IE60514B1 (en) 1994-07-27
FI87781B (fi) 1992-11-13
NO167202B (no) 1991-07-08
CA1323366C (en) 1993-10-19
GR3006841T3 (forum.php) 1993-06-30
DK479487D0 (da) 1987-09-14
IL83892A (en) 1991-11-21
NZ221729A (en) 1989-07-27
NO873840D0 (no) 1987-09-14
BG61321B2 (bg) 1997-05-30
AU595064B2 (en) 1990-03-22
HU198039B (en) 1989-07-28
IL83892A0 (en) 1988-02-29
CN87106423A (zh) 1988-04-20
FI873977A0 (fi) 1987-09-14
ES2053524T3 (es) 1994-08-01

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Effective date: 20070908