DK479487A - (1h-imidazol-1-ylmethyl)-substituerede benzimidazol-derivater - Google Patents

(1h-imidazol-1-ylmethyl)-substituerede benzimidazol-derivater

Info

Publication number
DK479487A
DK479487A DK479487A DK479487A DK479487A DK 479487 A DK479487 A DK 479487A DK 479487 A DK479487 A DK 479487A DK 479487 A DK479487 A DK 479487A DK 479487 A DK479487 A DK 479487A
Authority
DK
Denmark
Prior art keywords
imidazol
ylmethyl
benzimidazole derivatives
substituted benzimidazole
substituted
Prior art date
Application number
DK479487A
Other languages
English (en)
Other versions
DK479487D0 (da
DK174728B1 (da
Inventor
Alfons Herman Marg Raeymaekers
Eddy Jean Edgard Freyne
Gerard Charles Sanz
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of DK479487D0 publication Critical patent/DK479487D0/da
Publication of DK479487A publication Critical patent/DK479487A/da
Application granted granted Critical
Publication of DK174728B1 publication Critical patent/DK174728B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK198704794A 1986-09-15 1987-09-14 (1H-imidazol-1-ylmethyl)-substituerede benzimidazolderivater, fremgangsmåde til fremstilling deraf, farmaceutiske præparater indeholdende derivaterne og anvendelse af derivaterne til fremstilling af lægemidler DK174728B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90790386A 1986-09-15 1986-09-15
US90790386 1986-09-15

Publications (3)

Publication Number Publication Date
DK479487D0 DK479487D0 (da) 1987-09-14
DK479487A true DK479487A (da) 1988-03-16
DK174728B1 DK174728B1 (da) 2003-10-06

Family

ID=25424835

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198704794A DK174728B1 (da) 1986-09-15 1987-09-14 (1H-imidazol-1-ylmethyl)-substituerede benzimidazolderivater, fremgangsmåde til fremstilling deraf, farmaceutiske præparater indeholdende derivaterne og anvendelse af derivaterne til fremstilling af lægemidler

Country Status (23)

Country Link
EP (1) EP0260744B1 (da)
JP (1) JPS6485975A (da)
KR (1) KR960014353B1 (da)
CN (1) CN1020903C (da)
AU (1) AU595064B2 (da)
BG (1) BG61321B2 (da)
CA (1) CA1323366C (da)
CY (1) CY1803A (da)
DE (1) DE3783107T2 (da)
DK (1) DK174728B1 (da)
ES (1) ES2053524T3 (da)
FI (1) FI87781C (da)
GR (1) GR3006841T3 (da)
HK (1) HK123694A (da)
HU (1) HU198039B (da)
IE (1) IE60514B1 (da)
IL (1) IL83892A (da)
NO (1) NO167202C (da)
NZ (1) NZ221729A (da)
PH (1) PH25022A (da)
PT (1) PT85692B (da)
SU (1) SU1662350A3 (da)
ZA (1) ZA876881B (da)

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US5216003A (en) * 1992-01-02 1993-06-01 G. D. Searle & Co. Diacid-containing benzimidazole compounds for treatment of neurotoxic injury
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EP0745078A1 (en) * 1994-02-18 1996-12-04 Janssen Pharmaceutica N.V. Enantiomerically pure(-)-liarozole
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FR2751649B1 (fr) * 1996-07-26 1998-08-28 Adir Nouveaux derives de benzimidazole, de benzoxazole et de benzothiazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
IT1286866B1 (it) * 1996-10-28 1998-07-17 Menarini Farma Ind Composti furano-eterociclici,loro preparazione ed uso come inibitori di aromatasi
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TW453999B (en) 1997-06-27 2001-09-11 Fujisawa Pharmaceutical Co Benzimidazole derivatives
EP1037880B1 (en) 1997-12-11 2004-06-30 Janssen Pharmaceutica N.V. Retinoic acid mimetic anilides
DE19831985A1 (de) 1998-07-16 2000-01-20 Bayer Ag Substituierte Benzimidazole, ihre Herstellung und ihre Verwendung als Mittel gegen parasitäre Protozoen
US6858598B1 (en) 1998-12-23 2005-02-22 G. D. Searle & Co. Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
US6833373B1 (en) 1998-12-23 2004-12-21 G.D. Searle & Co. Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
ATE256666T1 (de) * 1999-06-04 2004-01-15 Elan Pharma Int Ltd Zusammensetzungen und methoden zur verhinderung des zelltods
JP3938689B2 (ja) 2000-03-16 2007-06-27 エフ．ホフマン−ラ ロシュ アーゲー Ｉｐアンタゴニストとしてのカルボン酸誘導体
CN100572363C (zh) 2000-11-17 2009-12-23 武田药品工业株式会社 咪唑衍生物、其制备方法及其用途
CA2429437A1 (en) 2000-11-20 2002-05-23 Takeda Chemical Industries, Ltd. Imidazole derivatives, process for their preparation and their use
CA2431171A1 (en) 2000-12-08 2002-06-13 Takeda Chemical Industries, Ltd. Substituted thiazole derivatives bearing 3-pyridyl groups, process for preparing the same and use thereof
US7405235B2 (en) 2001-05-04 2008-07-29 Paratek Pharmaceuticals, Inc. Transcription factor modulating compounds and methods of use thereof
US6492517B1 (en) 2001-07-19 2002-12-10 Air Products And Chemicals, Inc. Method for preparing halomethyl heterocyclic compounds
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Also Published As

Publication number Publication date
NO873840D0 (no) 1987-09-14
EP0260744B1 (en) 1992-12-16
SU1662350A3 (ru) 1991-07-07
BG61321B2 (bg) 1997-05-30
NO167202B (no) 1991-07-08
CA1323366C (en) 1993-10-19
DK479487D0 (da) 1987-09-14
AU595064B2 (en) 1990-03-22
KR960014353B1 (ko) 1996-10-15
ES2053524T3 (es) 1994-08-01
NO167202C (no) 1991-10-16
EP0260744A2 (en) 1988-03-23
FI873977A (fi) 1988-03-16
IE872487L (en) 1988-03-15
IE60514B1 (en) 1994-07-27
FI87781B (fi) 1992-11-13
DK174728B1 (da) 2003-10-06
HU198039B (en) 1989-07-28
AU7838587A (en) 1988-04-14
CN87106423A (zh) 1988-04-20
JPH0587071B2 (da) 1993-12-15
NZ221729A (en) 1989-07-27
IL83892A (en) 1991-11-21
IL83892A0 (en) 1988-02-29
CN1020903C (zh) 1993-05-26
NO873840L (no) 1988-03-16
PT85692B (pt) 1990-06-29
GR3006841T3 (da) 1993-06-30
PT85692A (en) 1987-10-01
DE3783107T2 (de) 1993-04-22
DE3783107D1 (de) 1993-01-28
EP0260744A3 (en) 1989-01-18
FI87781C (fi) 1993-02-25
CY1803A (en) 1987-09-09
KR880003935A (ko) 1988-06-01
JPS6485975A (en) 1989-03-30
ZA876881B (en) 1989-04-26
PH25022A (en) 1991-01-28
HUT45051A (en) 1988-05-30
FI873977A0 (fi) 1987-09-14
HK123694A (en) 1994-11-18

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