DK479487D0 - (1h-imidazol-1-ylmethyl)-substituerede benzimidazol-derivater - Google Patents

(1h-imidazol-1-ylmethyl)-substituerede benzimidazol-derivater

Info

Publication number
DK479487D0
DK479487D0 DK479487A DK479487A DK479487D0 DK 479487 D0 DK479487 D0 DK 479487D0 DK 479487 A DK479487 A DK 479487A DK 479487 A DK479487 A DK 479487A DK 479487 D0 DK479487 D0 DK 479487D0
Authority
DK
Denmark
Prior art keywords
imidazol
ylmethyl
benzimidazole derivatives
substituted benzimidazole
substituted
Prior art date
Application number
DK479487A
Other languages
English (en)
Other versions
DK479487A (da
DK174728B1 (da
Inventor
Alfons Herman Marg Raeymaekers
Eddy Jean Edgard Freyne
Gerard Charles Sanz
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of DK479487D0 publication Critical patent/DK479487D0/da
Publication of DK479487A publication Critical patent/DK479487A/da
Application granted granted Critical
Publication of DK174728B1 publication Critical patent/DK174728B1/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK198704794A 1986-09-15 1987-09-14 (1H-imidazol-1-ylmethyl)-substituerede benzimidazolderivater, fremgangsmåde til fremstilling deraf, farmaceutiske præparater indeholdende derivaterne og anvendelse af derivaterne til fremstilling af lægemidler DK174728B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90790386A 1986-09-15 1986-09-15
US90790386 1986-09-15

Publications (3)

Publication Number Publication Date
DK479487D0 true DK479487D0 (da) 1987-09-14
DK479487A DK479487A (da) 1988-03-16
DK174728B1 DK174728B1 (da) 2003-10-06

Family

ID=25424835

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198704794A DK174728B1 (da) 1986-09-15 1987-09-14 (1H-imidazol-1-ylmethyl)-substituerede benzimidazolderivater, fremgangsmåde til fremstilling deraf, farmaceutiske præparater indeholdende derivaterne og anvendelse af derivaterne til fremstilling af lægemidler

Country Status (23)

Country Link
EP (1) EP0260744B1 (da)
JP (1) JPS6485975A (da)
KR (1) KR960014353B1 (da)
CN (1) CN1020903C (da)
AU (1) AU595064B2 (da)
BG (1) BG61321B2 (da)
CA (1) CA1323366C (da)
CY (1) CY1803A (da)
DE (1) DE3783107T2 (da)
DK (1) DK174728B1 (da)
ES (1) ES2053524T3 (da)
FI (1) FI87781C (da)
GR (1) GR3006841T3 (da)
HK (1) HK123694A (da)
HU (1) HU198039B (da)
IE (1) IE60514B1 (da)
IL (1) IL83892A (da)
NO (1) NO167202C (da)
NZ (1) NZ221729A (da)
PH (1) PH25022A (da)
PT (1) PT85692B (da)
SU (1) SU1662350A3 (da)
ZA (1) ZA876881B (da)

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US5021448A (en) * 1990-02-22 1991-06-04 Ciba-Geigy Corporation Method of reducing serum uric acid and/or increasing renal uric acid clearance with thromboxane synthetase inhibitor inhibitor and/or thromboxane receptor antagonist
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SG52325A1 (en) * 1994-02-18 1998-09-28 Janssen Pharmaceutica Nv Enantiomerically pure(+)-liarozole
AU688852B2 (en) * 1994-02-18 1998-03-19 Janssen Pharmaceutica N.V. Enantiomerically pure(-)-liarozole
GB9418443D0 (en) * 1994-09-13 1994-11-02 Pfizer Ltd Therapeutic agents
CZ176197A3 (cs) * 1994-12-22 1998-09-16 Ligand Pharmaceuticals Incorporated Modulátory steroidových receptorů a způsoby jejich přípravy a použití
US6696459B1 (en) 1994-12-22 2004-02-24 Ligand Pharmaceuticals Inc. Steroid receptor modulator compounds and methods
US5693647A (en) * 1994-12-22 1997-12-02 Ligand Pharmaceuticals Incorporated Steroid receptor modulator compounds and methods
TW316902B (da) * 1994-12-28 1997-10-01 Janssen Pharmaceutica Nv
PL322028A1 (en) * 1995-03-01 1998-01-05 Yamanouchi Pharma Co Ltd Derivatives of imidazoles and pharmaceutic composition containing them
US6288100B1 (en) * 1995-06-06 2001-09-11 American Home Products Corporation Benzimidazole derivatives
DE19535500A1 (de) * 1995-09-25 1997-03-27 Bayer Ag Verfahren zur Herstellung von 3-Chlor-3'-nitro-4'-methoxybenzophenon
HUP9900625A3 (en) * 1995-12-28 2003-04-28 Fujisawa Pharmaceutical Co Benzimidazole derivatives, pharmaceutical compositions containing them and process for preparing the compounds
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FR2751649B1 (fr) * 1996-07-26 1998-08-28 Adir Nouveaux derives de benzimidazole, de benzoxazole et de benzothiazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
IT1286866B1 (it) * 1996-10-28 1998-07-17 Menarini Farma Ind Composti furano-eterociclici,loro preparazione ed uso come inibitori di aromatasi
HUP0000312A3 (en) * 1996-11-25 2001-12-28 Procter And Gamble Co Cincinna Guanidinyl heterocycle compounds useful as alpha-2 adrenoceptor agonists and pharmaceutical compositions containing them
WO1998037070A1 (en) * 1997-02-21 1998-08-27 Takeda Chemical Industries, Ltd. Fused ring compounds, process for producing the same and use thereof
TW453999B (en) 1997-06-27 2001-09-11 Fujisawa Pharmaceutical Co Benzimidazole derivatives
TR200001645T2 (tr) 1997-12-11 2000-12-21 Janssen Pharmaceutica N.V. Retinoyik asit taklidi anilürler.
DE19831985A1 (de) 1998-07-16 2000-01-20 Bayer Ag Substituierte Benzimidazole, ihre Herstellung und ihre Verwendung als Mittel gegen parasitäre Protozoen
US6833373B1 (en) 1998-12-23 2004-12-21 G.D. Searle & Co. Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
US6858598B1 (en) 1998-12-23 2005-02-22 G. D. Searle & Co. Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
AU5314900A (en) * 1999-06-04 2000-12-28 Elan Pharma International Limited Compositions and methods for inhibiting cell death
NZ521028A (en) 2000-03-16 2004-07-30 F Carboxylic acid derivatives as IP antagonists
JP3753971B2 (ja) 2000-11-17 2006-03-08 武田薬品工業株式会社 新規イミダゾール誘導体、その製造法および用途
DE60144246D1 (de) 2000-11-20 2011-04-28 Takeda Pharmaceutical Imidazolderivate, verfahren zu deren herstellung und deren verwendung
AU2002221080A1 (en) 2000-12-08 2002-06-18 Masami Kusaka Substituted thiazole derivatives bearing 3-pyridyl groups, process for preparingthe same and use thereof
US7405235B2 (en) 2001-05-04 2008-07-29 Paratek Pharmaceuticals, Inc. Transcription factor modulating compounds and methods of use thereof
US6492517B1 (en) * 2001-07-19 2002-12-10 Air Products And Chemicals, Inc. Method for preparing halomethyl heterocyclic compounds
US7253154B2 (en) * 2001-11-16 2007-08-07 Nippon Chemiphar Co., Ltd. Substituted thiazolopyrimidines as xanthine oxidase inhibitors
JP2006513162A (ja) * 2002-11-01 2006-04-20 パラテック ファーマシューティカルズ インコーポレイテッド 転写因子調節化合物およびその使用方法
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PL1984343T3 (pl) * 2006-01-24 2013-08-30 Janssen Pharmaceutica Nv 2-podstawione benzimidazole jako selektywne modulatory receptora androgenowego (SARM)
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Also Published As

Publication number Publication date
ES2053524T3 (es) 1994-08-01
HK123694A (en) 1994-11-18
IL83892A0 (en) 1988-02-29
CN1020903C (zh) 1993-05-26
NO873840L (no) 1988-03-16
CY1803A (en) 1987-09-09
EP0260744A2 (en) 1988-03-23
EP0260744B1 (en) 1992-12-16
NO167202C (no) 1991-10-16
JPH0587071B2 (da) 1993-12-15
NO167202B (no) 1991-07-08
EP0260744A3 (en) 1989-01-18
FI87781C (fi) 1993-02-25
SU1662350A3 (ru) 1991-07-07
DE3783107T2 (de) 1993-04-22
AU595064B2 (en) 1990-03-22
FI87781B (fi) 1992-11-13
DE3783107D1 (de) 1993-01-28
IE872487L (en) 1988-03-15
HUT45051A (en) 1988-05-30
CA1323366C (en) 1993-10-19
IL83892A (en) 1991-11-21
DK479487A (da) 1988-03-16
DK174728B1 (da) 2003-10-06
PT85692B (pt) 1990-06-29
BG61321B2 (bg) 1997-05-30
NZ221729A (en) 1989-07-27
FI873977A7 (fi) 1988-03-16
GR3006841T3 (da) 1993-06-30
PH25022A (en) 1991-01-28
AU7838587A (en) 1988-04-14
CN87106423A (zh) 1988-04-20
FI873977A0 (fi) 1987-09-14
KR880003935A (ko) 1988-06-01
HU198039B (en) 1989-07-28
JPS6485975A (en) 1989-03-30
ZA876881B (en) 1989-04-26
NO873840D0 (no) 1987-09-14
IE60514B1 (en) 1994-07-27
PT85692A (en) 1987-10-01
KR960014353B1 (ko) 1996-10-15

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