HK1205525A1 - Hyaluronic acid derivative having amino acid and steryl group introduced thereinto - Google Patents
Hyaluronic acid derivative having amino acid and steryl group introduced thereintoInfo
- Publication number
- HK1205525A1 HK1205525A1 HK15106154.2A HK15106154A HK1205525A1 HK 1205525 A1 HK1205525 A1 HK 1205525A1 HK 15106154 A HK15106154 A HK 15106154A HK 1205525 A1 HK1205525 A1 HK 1205525A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- group introduced
- amino acid
- introduced thereinto
- hyaluronic acid
- steryl group
- Prior art date
Links
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical class CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title 1
- 150000001413 amino acids Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012195528 | 2012-09-05 | ||
| PCT/JP2013/073995 WO2014038641A1 (ja) | 2012-09-05 | 2013-09-05 | アミノ酸およびステリル基が導入されたヒアルロン酸誘導体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1205525A1 true HK1205525A1 (en) | 2015-12-18 |
Family
ID=50237247
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK15106154.2A HK1205525A1 (en) | 2012-09-05 | 2015-06-29 | Hyaluronic acid derivative having amino acid and steryl group introduced thereinto |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US11564971B2 (ru) |
| EP (1) | EP2894173B1 (ru) |
| JP (1) | JP6275044B2 (ru) |
| KR (1) | KR102130864B1 (ru) |
| CN (1) | CN104603156B (ru) |
| BR (1) | BR112015004501B1 (ru) |
| CA (1) | CA2884142C (ru) |
| HK (1) | HK1205525A1 (ru) |
| MX (1) | MX359884B (ru) |
| RU (1) | RU2674003C2 (ru) |
| WO (1) | WO2014038641A1 (ru) |
Families Citing this family (21)
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|---|---|---|---|---|
| WO2015044455A1 (en) * | 2013-09-30 | 2015-04-02 | Galderma S.A. | Single-step functionalization and cross-linking of hyaluronic acid |
| JP6613300B2 (ja) * | 2015-03-31 | 2019-11-27 | キユーピー株式会社 | ヒアルロン酸誘導体およびその製造方法、ならびにヒアルロン酸誘導体を含む化粧料、食品組成物および医薬組成物 |
| US11389539B2 (en) | 2016-05-11 | 2022-07-19 | Chugai Seiyaku Kabushiki Kaisha | Hyaluronic acid derivatives into which cationic and hydrophobic groups are introduced |
| CN108069867A (zh) * | 2016-11-17 | 2018-05-25 | 常州百凯生物科技有限公司 | 一种l-丙氨酰胺盐酸盐的制备方法 |
| IT201700122135A1 (it) * | 2017-10-26 | 2019-04-26 | Jointherapeutics S R L | Acido ialuronico funzionalizzato o suo derivato nel trattamento di stati infiammatori |
| US11512147B2 (en) | 2017-11-15 | 2022-11-29 | Chugai Seiyaku Kabushiki Kaisha | Hyaluronic acid derivative modified with polyethylene glycol |
| IT201800003841A1 (it) | 2018-03-21 | 2019-09-21 | Acme Drugs S R L | Coniugati di stanozololo e acido ialuronico |
| US20220160849A1 (en) * | 2019-01-29 | 2022-05-26 | Mie University | Cancer vaccine formulation |
| US20220213233A1 (en) * | 2019-04-19 | 2022-07-07 | Jointherapeutics S.R.L. | Crosslinked polymer of functionalized hyaluronic acid and its use in the treatment of inflammatory states |
| AU2020288834B2 (en) * | 2019-06-03 | 2022-12-22 | Aihol Corporation | Hyaluronan conjugates and uses thereof |
| JP7502861B2 (ja) | 2019-12-27 | 2024-06-19 | 旭化成株式会社 | 標的物質と両親媒性高分子との複合体の形成反応の反応温度の評価方法 |
| TWI834948B (zh) * | 2020-02-05 | 2024-03-11 | 日商旭化成股份有限公司 | 玻尿酸衍生物組合物、醫藥組合物及玻尿酸衍生物－藥物結合體組合物 |
| CN118108876A (zh) * | 2020-02-07 | 2024-05-31 | 旭化成株式会社 | 透明质酸衍生物、药物组合物和透明质酸衍生物-药物结合体 |
| KR20210102602A (ko) | 2020-02-12 | 2021-08-20 | (주)아모레퍼시픽 | 생체 활성 물질을 안정화하는 히알루론산 하이드로겔 및 이의 제조 방법 |
| CN115867319B (zh) * | 2020-07-15 | 2024-01-02 | 上海椿安生物医药科技有限公司 | 用于局部递送治疗剂的药物递送系统以及其用途 |
| CN116322642B (zh) * | 2020-08-14 | 2024-08-23 | 国立大学法人东京大学 | 多糖衍生物、多糖衍生物-药物缀合物、其制造方法 |
| EP4349366A1 (en) | 2021-05-31 | 2024-04-10 | Mie University | Pharmaceutical composition |
| CN114931563A (zh) * | 2022-03-17 | 2022-08-23 | 吉林大学 | 一种透明质酸纳米颗粒/维替泊芬复合物的制备方法 |
| CN115466339A (zh) * | 2022-05-13 | 2022-12-13 | 宁波格鲁康生物科技有限公司 | 生物安全注射用改性透明质酸、制备方法及其在美容注射材料上的应用 |
| CN115850534B (zh) * | 2022-12-16 | 2024-03-12 | 浙江大学 | 一种透明质酸-胆酸衍生物及其合成方法和应用 |
| CN116763725B (zh) * | 2023-08-16 | 2023-11-24 | 四川大学华西医院 | 一种智能响应型可注射水凝胶及其制备方法和应用 |
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| EP0416250A3 (en) * | 1989-08-01 | 1991-08-28 | The Research Foundation Of State University Of New York | N-acylurea and o-acylisourea derivatives of hyaluronic acid |
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| AU652784B2 (en) | 1990-10-18 | 1994-09-08 | Shiseido Company Ltd. | Combination of hyaluronic acid with medicinal ingredient and production thereof |
| JPH0585942A (ja) | 1991-02-26 | 1993-04-06 | Denki Kagaku Kogyo Kk | インターフエロン−ヒアルロン酸及び／又はその塩の結合体 |
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| JP5406281B2 (ja) * | 2009-04-17 | 2014-02-05 | 帝人株式会社 | 多糖類誘導体およびそのハイドロゲル |
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| WO2011148116A2 (fr) | 2010-05-27 | 2011-12-01 | Laboratoire Idenov | Acide hyaluronique modifie, procede de fabrication et utilisations |
| JP5594093B2 (ja) | 2010-11-30 | 2014-09-24 | ブラザー工業株式会社 | 現像装置 |
| WO2012118189A1 (ja) * | 2011-03-03 | 2012-09-07 | 中外製薬株式会社 | アミノ－カルボン酸により修飾されたヒアルロン酸誘導体 |
-
2013
- 2013-09-05 CN CN201380046295.XA patent/CN104603156B/zh active Active
- 2013-09-05 JP JP2014534410A patent/JP6275044B2/ja active Active
- 2013-09-05 EP EP13836138.1A patent/EP2894173B1/en active Active
- 2013-09-05 CA CA2884142A patent/CA2884142C/en active Active
- 2013-09-05 KR KR1020157008082A patent/KR102130864B1/ko active IP Right Grant
- 2013-09-05 BR BR112015004501-4A patent/BR112015004501B1/pt active IP Right Grant
- 2013-09-05 WO PCT/JP2013/073995 patent/WO2014038641A1/ja active Application Filing
- 2013-09-05 US US14/426,485 patent/US11564971B2/en active Active
- 2013-09-05 MX MX2015002847A patent/MX359884B/es active IP Right Grant
- 2013-09-05 RU RU2015112219A patent/RU2674003C2/ru active
-
2015
- 2015-06-29 HK HK15106154.2A patent/HK1205525A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US11564971B2 (en) | 2023-01-31 |
| JP6275044B2 (ja) | 2018-02-07 |
| JPWO2014038641A1 (ja) | 2016-08-12 |
| MX359884B (es) | 2018-10-15 |
| BR112015004501B1 (pt) | 2021-04-13 |
| EP2894173A4 (en) | 2016-05-25 |
| US20150231268A1 (en) | 2015-08-20 |
| BR112015004501A2 (pt) | 2017-07-04 |
| RU2015112219A (ru) | 2016-10-27 |
| CA2884142A1 (en) | 2014-03-13 |
| CN104603156A (zh) | 2015-05-06 |
| EP2894173A1 (en) | 2015-07-15 |
| MX2015002847A (es) | 2015-05-15 |
| CA2884142C (en) | 2020-11-10 |
| CN104603156B (zh) | 2016-10-26 |
| WO2014038641A1 (ja) | 2014-03-13 |
| KR102130864B1 (ko) | 2020-07-08 |
| KR20150048238A (ko) | 2015-05-06 |
| RU2674003C2 (ru) | 2018-12-04 |
| EP2894173B1 (en) | 2017-04-19 |
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