HK1158634A1 - Novel compounds useful for the treatment of degenerative and inflammatory diseases - Google Patents

Novel compounds useful for the treatment of degenerative and inflammatory diseases

Info

Publication number
HK1158634A1
HK1158634A1 HK11112985.9A HK11112985A HK1158634A1 HK 1158634 A1 HK1158634 A1 HK 1158634A1 HK 11112985 A HK11112985 A HK 11112985A HK 1158634 A1 HK1158634 A1 HK 1158634A1
Authority
HK
Hong Kong
Prior art keywords
diseases
disease
treatment
cartilage
involving
Prior art date
Application number
HK11112985.9A
Other languages
English (en)
Inventor
Christel Jeanne Marie Menet
Javier Blanc
Original Assignee
Galapagos Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galapagos Nv filed Critical Galapagos Nv
Publication of HK1158634A1 publication Critical patent/HK1158634A1/xx

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/541—Non-condensed thiazines containing further heterocyclic rings
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    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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    • C07D471/04—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Toxicology (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Otolaryngology (AREA)
  • Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HK11112985.9A 2008-07-25 2011-11-30 Novel compounds useful for the treatment of degenerative and inflammatory diseases HK1158634A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13592008P 2008-07-25 2008-07-25
US22068509P 2009-06-26 2009-06-26
PCT/EP2009/059605 WO2010010191A1 (en) 2008-07-25 2009-07-24 Novel compounds useful for the treatment of degenerative and inflammatory diseases.

Publications (1)

Publication Number Publication Date
HK1158634A1 true HK1158634A1 (en) 2012-07-20

Family

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Application Number Title Priority Date Filing Date
HK11112985.9A HK1158634A1 (en) 2008-07-25 2011-11-30 Novel compounds useful for the treatment of degenerative and inflammatory diseases
HK11112990.2A HK1158635A1 (en) 2008-07-25 2011-11-30 Novel compounds useful for the treatment of degenerative and inflammatory diseases

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK11112990.2A HK1158635A1 (en) 2008-07-25 2011-11-30 Novel compounds useful for the treatment of degenerative and inflammatory diseases

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US (5) US8853240B2 (xx)
EP (2) EP2361251B1 (xx)
JP (2) JP5559168B2 (xx)
KR (2) KR101711911B1 (xx)
CN (2) CN102105471B (xx)
AR (1) AR072875A1 (xx)
AU (2) AU2009273143B2 (xx)
BR (2) BRPI0916659B8 (xx)
CA (2) CA2730757A1 (xx)
CL (1) CL2009001637A1 (xx)
CO (1) CO6361925A2 (xx)
CR (1) CR20110092A (xx)
CY (2) CY1113945T1 (xx)
DK (2) DK2346864T3 (xx)
DO (1) DOP2011000022A (xx)
EA (2) EA018080B1 (xx)
ES (2) ES2406691T3 (xx)
HK (2) HK1158634A1 (xx)
HR (2) HRP20130357T1 (xx)
IL (2) IL210261A (xx)
JO (1) JO3041B1 (xx)
MA (1) MA32551B1 (xx)
ME (1) ME02046B (xx)
MX (2) MX2011000758A (xx)
MY (1) MY157615A (xx)
NZ (1) NZ590646A (xx)
PE (1) PE20100152A1 (xx)
PL (2) PL2346864T3 (xx)
PT (2) PT2346864E (xx)
RS (2) RS53406B (xx)
SI (2) SI2346864T1 (xx)
SM (2) SMT201300051B (xx)
TW (1) TWI447118B (xx)
UY (1) UY32006A (xx)
WO (2) WO2010010190A1 (xx)
ZA (2) ZA201100396B (xx)

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GB0719803D0 (en) 2007-10-10 2007-11-21 Cancer Rec Tech Ltd Therapeutic compounds and their use
JO3041B1 (ar) 2008-07-25 2016-09-05 Galapagos Nv مركبات جديدة مفيدة لمعالجة الأمراض التنكسية والالتهابية
WO2010141796A2 (en) 2009-06-05 2010-12-09 Cephalon, Inc. PREPARATION AND USES OF 1,2,4-TRIAZOLO [1,5a] PYRIDINE DERIVATIVES
CA2708690A1 (en) * 2009-06-26 2010-12-26 Markus Braun Process for producing cellulose beads from solutions of cellulose in ionic liquid
JO3030B1 (ar) * 2009-06-26 2016-09-05 Galapagos Nv مركب جديد مفيد لمعالجة الامراض التنكسية والالتهابات
TWI462920B (zh) * 2009-06-26 2014-12-01 葛萊伯格有限公司 用於治療退化性及發炎疾病之新穎化合物
EP2566333A4 (en) 2010-05-07 2014-04-02 Univ Leland Stanford Junior IDENTIFICATION OF STABILIZERS OF MULTIMEDER PROTEINS
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