HK1070896A1 - Nicotinamide derivatives useful as p38 inhibitors - Google Patents

Nicotinamide derivatives useful as p38 inhibitors

Info

Publication number
HK1070896A1
HK1070896A1 HK05103699A HK05103699A HK1070896A1 HK 1070896 A1 HK1070896 A1 HK 1070896A1 HK 05103699 A HK05103699 A HK 05103699A HK 05103699 A HK05103699 A HK 05103699A HK 1070896 A1 HK1070896 A1 HK 1070896A1
Authority
HK
Hong Kong
Prior art keywords
inhibitors
derivatives useful
nicotinamide derivatives
kinase
useful
Prior art date
Application number
HK05103699A
Other languages
English (en)
Inventor
Aston Nicola Mary
Bamborough Paul
Walker Ann Louise
Original Assignee
Smihkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0203301.7A external-priority patent/GB0203301D0/en
Priority claimed from GB0225385A external-priority patent/GB0225385D0/en
Application filed by Smihkline Beecham Corp filed Critical Smihkline Beecham Corp
Priority to HK08103321.6A priority Critical patent/HK1113056A1/xx
Publication of HK1070896A1 publication Critical patent/HK1070896A1/xx

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    • C—CHEMISTRY; METALLURGY
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    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
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HK05103699A 2002-02-12 2005-04-29 Nicotinamide derivatives useful as p38 inhibitors HK1070896A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
HK08103321.6A HK1113056A1 (en) 2002-02-12 2005-04-29 Nicotinamide derivates useful as p38 inhibitors

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0203301.7A GB0203301D0 (en) 2002-02-12 2002-02-12 Novel compounds
GB0225385A GB0225385D0 (en) 2002-10-31 2002-10-31 Novel compounds
PCT/GB2003/000554 WO2003068747A1 (fr) 2002-02-12 2003-02-10 Derives de nicotinamide utiles comme inhibiteurs de p38

Publications (1)

Publication Number Publication Date
HK1070896A1 true HK1070896A1 (en) 2005-06-30

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ID=27736200

Family Applications (2)

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HK1113056A1 (en) 2008-09-19
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CY1107117T1 (el) 2012-01-25
SI1864975T1 (sl) 2011-01-31
EP1474395A1 (fr) 2004-11-10
IL163090A (en) 2010-06-16
AU2003207298B2 (en) 2009-09-03
CA2474192C (fr) 2011-06-21
EP2258687B1 (fr) 2012-12-26
CO5611147A2 (es) 2006-02-28
US7125898B2 (en) 2006-10-24
US7514456B2 (en) 2009-04-07
PL212910B1 (pl) 2012-12-31
DE60316913T2 (de) 2008-11-20
DK1474395T3 (da) 2008-02-11
CN1633416A (zh) 2005-06-29
RU2309951C2 (ru) 2007-11-10
US7709506B2 (en) 2010-05-04
EP1864975A2 (fr) 2007-12-12
PT1474395E (pt) 2008-01-02
PT1864975E (pt) 2010-12-27
US20060276516A1 (en) 2006-12-07
MXPA04007838A (es) 2004-10-15
PL372628A1 (en) 2005-07-25
IS2520B (is) 2009-07-15
EP1474395B1 (fr) 2007-10-17
US8575204B2 (en) 2013-11-05
JP2005519932A (ja) 2005-07-07
BRPI0307351B1 (pt) 2018-09-04
CA2474192A1 (fr) 2003-08-21
ATE375980T1 (de) 2007-11-15
US8252818B2 (en) 2012-08-28
AU2003207298A1 (en) 2003-09-04
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DE60334651D1 (de) 2010-12-02
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ATE485275T1 (de) 2010-11-15
DE60316913D1 (de) 2007-11-29
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IS7337A (is) 2004-06-28
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US20060264479A1 (en) 2006-11-23
BRPI0307351B8 (pt) 2021-05-25
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