HK1022840A1 - Pellets having a core coated with an antifungal and a polymer - Google Patents

Pellets having a core coated with an antifungal and a polymer

Info

Publication number
HK1022840A1
HK1022840A1 HK00101919A HK00101919A HK1022840A1 HK 1022840 A1 HK1022840 A1 HK 1022840A1 HK 00101919 A HK00101919 A HK 00101919A HK 00101919 A HK00101919 A HK 00101919A HK 1022840 A1 HK1022840 A1 HK 1022840A1
Authority
HK
Hong Kong
Prior art keywords
antifungal
pellets
polymer
core coated
coated
Prior art date
Application number
HK00101919A
Other languages
English (en)
Inventor
Roger Petrus Gerebe Vandecruys
Conde Valentin Florent Vict De
Paul Marie Victor Gilis
Josef Peeters
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of HK1022840A1 publication Critical patent/HK1022840A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
HK00101919A 1997-03-26 2000-03-29 Pellets having a core coated with an antifungal and a polymer HK1022840A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97200914 1997-03-26
PCT/EP1998/001773 WO1998042318A1 (fr) 1997-03-26 1998-03-18 Comprimes a noyau enrobe d'un agent antifongique et d'un polymere

Publications (1)

Publication Number Publication Date
HK1022840A1 true HK1022840A1 (en) 2000-08-25

Family

ID=8228147

Family Applications (1)

Application Number Title Priority Date Filing Date
HK00101919A HK1022840A1 (en) 1997-03-26 2000-03-29 Pellets having a core coated with an antifungal and a polymer

Country Status (31)

Country Link
EP (1) EP0969821B1 (fr)
JP (1) JP3608800B2 (fr)
KR (1) KR100520936B1 (fr)
CN (1) CN1206984C (fr)
AP (1) AP1227A (fr)
AT (1) ATE241969T1 (fr)
AU (1) AU734248B2 (fr)
BG (1) BG64434B1 (fr)
BR (1) BR9806174A (fr)
CA (1) CA2269501C (fr)
CY (1) CY2384B1 (fr)
CZ (1) CZ295502B6 (fr)
DE (1) DE69815316T2 (fr)
DK (1) DK0969821T3 (fr)
EE (1) EE03904B1 (fr)
ES (1) ES2201485T3 (fr)
HK (1) HK1022840A1 (fr)
HU (1) HU224217B1 (fr)
ID (1) ID21477A (fr)
IL (1) IL129575A (fr)
NO (1) NO325102B1 (fr)
NZ (1) NZ335364A (fr)
OA (1) OA11162A (fr)
PL (1) PL190566B1 (fr)
PT (1) PT969821E (fr)
RU (1) RU2218153C2 (fr)
SI (1) SI0969821T1 (fr)
SK (1) SK284813B6 (fr)
TR (1) TR199900990T2 (fr)
UA (1) UA60318C2 (fr)
WO (1) WO1998042318A1 (fr)

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BR9906712A (pt) * 1998-07-17 2000-10-10 Janssen Pharmaceutica Nv Péletes que apresentam um núcleo revestido com um antifúngico e um polìmero
ES2157731B1 (es) * 1998-07-21 2002-05-01 Liconsa Liberacion Controlada Preparacion farmaceutica oral de un compuesto de actividad antifungica y procedimiento para su preparacion.
CA2362728C (fr) 1999-03-24 2009-06-23 Fmc Corporation Formulations pharmaceutiques a solubilite aqueuse amelioree
KR100432949B1 (ko) * 2000-06-13 2004-05-31 코오롱제약주식회사 생체이용율이 향상된 이트라코나졸의 분립체 조성물과이를 이용한 이트라코나졸 제제 및 그 제조방법
US6663897B2 (en) * 2001-02-06 2003-12-16 Dsm Ip Assets B.V. Oral itraconazole formulations and methods of making the same
CZ304273B6 (cs) 2001-02-14 2014-02-12 Tibotec Pharmaceuticals Ltd. 2-(Substitovaná-amino)benzothiazolsulfonamidová sloučenina, způsob její přípravy a farmaceutická kompozice s jejím obsahem
OA12464A (en) 2001-04-09 2006-05-24 Tibotec Pharm Ltd Broadspectrum 2-(substituted-amino)-benzoxazole sulfonamide HIV protease inhibitors.
US7622490B2 (en) 2001-05-11 2009-11-24 Tibotec Pharmaceuticals, Ltd. Broadspecturm 2-amino-benzoxazole sulfonamide HIV protease inhibitors
WO2002100407A1 (fr) * 2001-06-12 2002-12-19 Smartrix Technologies Inc. Granules d'itraconazole: formulations pharmaceutiques pour administration orale et procede de preparation de ces dernieres
US8071133B2 (en) 2001-08-20 2011-12-06 Stiefel Laboratories, Inc. Oral dosage forms of water insoluble drugs and methods of making the same
EA009556B1 (ru) 2001-12-21 2008-02-28 Тиботек Фармасьютикалз Лтд. Гетероциклические замещённые фенилсодержащие сульфонамиды широкого спектра действия в качестве ингибиторов протеазы вич
MY142238A (en) 2002-03-12 2010-11-15 Tibotec Pharm Ltd Broadspectrum substituted benzimidazole sulfonamide hiv protease inhibitors
MXPA04011466A (es) 2002-05-17 2005-02-14 Tibotec Pharm Ltd Inhibidores de la proteasa de hiv de benzisoxazol sulfonamida sustituida de amplio espectro.
CA2493940C (fr) 2002-08-14 2011-11-22 Tibotec Pharmaceuticals Ltd. Oxindole sulfonamides substitues inhibiteurs a large spectre de la protease du vih
KR100557680B1 (ko) * 2002-11-23 2006-03-07 한국유나이티드제약 주식회사 이트라코나졸의 용해도 개선을 위한 펠렛제제 및 그제조방법
DK1438961T4 (da) * 2003-01-14 2014-11-17 Acino Pharma Ag Bioækvivalent sammensætning af itraconazol dispergeret i en hydrofil polymer
DK1438960T4 (da) * 2003-01-14 2013-03-25 Cimex Pharma Ag Sammensætning af itraconazol dispergeret i en hydrofil polymer med forhøjet biotilgængelighed
KR20060095863A (ko) * 2003-08-06 2006-09-04 니르말 뮬레 수용성 의약을 함유하는 제약학적 조성물
ATE532509T1 (de) 2003-09-11 2011-11-15 Tibotec Pharm Ltd Mittel zur hemmung des eintritts des hiv-virus
EP1568369A1 (fr) 2004-02-23 2005-08-31 Boehringer Ingelheim Vetmedica Gmbh Utilisation du meloxicam pour le traitement de maladies respiratoires des porcs
AR048650A1 (es) 2004-05-04 2006-05-10 Tibotec Pharm Ltd Derivados de (1,10b-dihidro-2-(aminocarbonil-fenil)-5h-pirazolo[1,5 c][1,3]benzoxazin-5-il)fenil metanona como inhibidores de la replicacion viral del vih
JP5073480B2 (ja) 2004-05-07 2012-11-14 セコイア、ファーマシューティカルズ、インコーポレイテッド 耐性防止レトロウイルスプロテアーゼ阻害薬
BRPI0511175A (pt) 2004-05-17 2007-12-04 Tibotec Pharm Ltd 1-hetero-ciclil-1,5-diidro-pirido[3,2-b]indol-2-onas
US7622582B2 (en) 2004-05-17 2009-11-24 Tibotec Bvba Derivatives of 1-phenyl-benzofuro[3,2]pyridin-2(1H)-one
AR049637A1 (es) 2004-05-17 2006-08-23 Tibotec Pharm Ltd 1-fenil-1,5-dihidro-pirido[3,2-b]indol-2-onas sustituidas en las posiciones 6, 7, 8, 9
EP2004647A1 (fr) 2006-04-03 2008-12-24 Tibotec Pharmaceuticals Ltd. 3,4-dihydro-imidazoý4,5-b¨pyridin-5-ones inhibant le vih
RU2420268C2 (ru) * 2006-09-04 2011-06-10 Панацея Биотек Лимитед Способ программируемой плавучей доставки
KR100809903B1 (ko) * 2006-09-05 2008-03-06 주식회사유한양행 안정화된 클로피도그렐-함유 입자, 그의 제조방법, 및 이를포함하는 약학 조성물
CN101283984B (zh) * 2007-04-12 2010-05-26 永胜药品工业股份有限公司 高生物使用率的经杀真菌剂和聚合物涂覆的核心微粒状物
JP2008280254A (ja) * 2007-05-08 2008-11-20 Everest Pharm Industrial Co Ltd 生体に使用される比率が高い、殺菌剤と重合物を塗粧してる核心微粒状物
US8313527B2 (en) 2007-11-05 2012-11-20 Allergan, Inc. Soft prosthesis shell texturing method
CN101965186A (zh) 2007-11-28 2011-02-02 塞阔伊亚药品公司 抑制细胞色素p450 2d6的化合物和方法
EP2257160B1 (fr) 2008-02-21 2017-07-05 Sequoia Pharmaceuticals, Inc. Diamides inhibiteurs du cytochrome p450
US9050184B2 (en) 2008-08-13 2015-06-09 Allergan, Inc. Dual plane breast implant
US8877822B2 (en) 2010-09-28 2014-11-04 Allergan, Inc. Porogen compositions, methods of making and uses
US9205577B2 (en) 2010-02-05 2015-12-08 Allergan, Inc. Porogen compositions, methods of making and uses
US9138309B2 (en) 2010-02-05 2015-09-22 Allergan, Inc. Porous materials, methods of making and uses
GB2479213B (en) 2010-04-01 2013-07-10 Theravida Inc Pharmaceutical formulations for the treatment of overactive bladder
US11202853B2 (en) 2010-05-11 2021-12-21 Allergan, Inc. Porogen compositions, methods of making and uses
CA2799201C (fr) * 2010-05-11 2016-09-20 Allergan, Inc. Compositions d'agents porogenes, leurs procedes de fabrication et utilisations
US8679279B2 (en) 2010-11-16 2014-03-25 Allergan, Inc. Methods for creating foam-like texture
CN102100678B (zh) * 2011-02-18 2012-10-17 天津力生制药股份有限公司 伊曲康唑硫酸盐微丸及其制备方法
EP2962662A1 (fr) 2012-12-13 2016-01-06 Allergan, Inc. Implant mammaire de surface variable
US10092392B2 (en) 2014-05-16 2018-10-09 Allergan, Inc. Textured breast implant and methods of making same
CN108697688A (zh) 2016-01-20 2018-10-23 塞拉维达公司 用于治疗多汗症的方法和组合物
JP7382957B2 (ja) * 2018-04-16 2023-11-17 ブリストル－マイヤーズ スクイブ カンパニー アピキサバン製剤
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DE3346123A1 (de) * 1983-12-21 1985-06-27 Janssen Pharmaceutica, N.V., Beerse Pharmazeutische praeparate von in wasser schwerloeslichen oder instabilen arzneistoffen und verfahren zu ihrer herstellung
GB8506792D0 (en) * 1985-03-15 1985-04-17 Janssen Pharmaceutica Nv Derivatives of y-cyclodextrin
PH30929A (en) * 1992-09-03 1997-12-23 Janssen Pharmaceutica Nv Beads having a core coated with an antifungal and a polymer.
HUP9903869A3 (en) * 1996-06-28 2000-07-28 Schering Corp Oral composition comprising a triazole antifungal compound

Also Published As

Publication number Publication date
CN1244796A (zh) 2000-02-16
DK0969821T3 (da) 2003-09-15
HU224217B1 (hu) 2005-06-28
JP3608800B2 (ja) 2005-01-12
JP2001520663A (ja) 2001-10-30
EE9900453A (et) 2000-04-17
DE69815316D1 (de) 2003-07-10
ES2201485T3 (es) 2004-03-16
CA2269501A1 (fr) 1998-10-01
SK284813B6 (sk) 2005-12-01
EP0969821A1 (fr) 2000-01-12
CZ295502B6 (cs) 2005-08-17
CN1206984C (zh) 2005-06-22
BG64434B1 (en) 2005-02-28
CY2384B1 (en) 2004-06-04
AU7210798A (en) 1998-10-20
TR199900990T2 (xx) 1999-10-21
AP9901516A0 (en) 1999-06-30
HUP0002056A3 (en) 2001-01-29
IL129575A0 (en) 2000-02-29
CA2269501C (fr) 2005-11-08
BG103356A (en) 2000-03-31
WO1998042318A1 (fr) 1998-10-01
HUP0002056A2 (hu) 2000-12-28
AU734248B2 (en) 2001-06-07
NO992114D0 (no) 1999-04-30
KR20000052971A (ko) 2000-08-25
AP1227A (en) 2003-11-24
PT969821E (pt) 2003-10-31
SK54499A3 (en) 2000-01-18
PL190566B1 (pl) 2005-12-30
ID21477A (id) 1999-06-17
UA60318C2 (uk) 2003-10-15
OA11162A (en) 2003-04-16
EP0969821B1 (fr) 2003-06-04
EE03904B1 (et) 2002-12-16
ATE241969T1 (de) 2003-06-15
NO325102B1 (no) 2008-02-04
IL129575A (en) 2004-06-20
BR9806174A (pt) 1999-10-19
PL335542A1 (en) 2000-04-25
DE69815316T2 (de) 2004-04-29
NZ335364A (en) 2000-08-25
KR100520936B1 (ko) 2005-10-17
RU2218153C2 (ru) 2003-12-10
CZ139899A3 (cs) 1999-10-13
SI0969821T1 (en) 2003-10-31
NO992114L (no) 1999-08-26

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Effective date: 20180317