HK1021511A1 - Granulate for the preparation of fast-disintegrating and fast-dissolving compositions containing a high amount of drug - Google Patents

Granulate for the preparation of fast-disintegrating and fast-dissolving compositions containing a high amount of drug

Info

Publication number
HK1021511A1
HK1021511A1 HK00100533A HK00100533A HK1021511A1 HK 1021511 A1 HK1021511 A1 HK 1021511A1 HK 00100533 A HK00100533 A HK 00100533A HK 00100533 A HK00100533 A HK 00100533A HK 1021511 A1 HK1021511 A1 HK 1021511A1
Authority
HK
Hong Kong
Prior art keywords
fast
granulate
disintegrating
drug
preparation
Prior art date
Application number
HK00100533A
Other languages
English (en)
Inventor
Bernardus Leonardus Dijkgraaf
Aart Muhlenbruch
Original Assignee
Yamanouchi Europ Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8224133&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1021511(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Yamanouchi Europ Bv filed Critical Yamanouchi Europ Bv
Publication of HK1021511A1 publication Critical patent/HK1021511A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Jellies, Jams, And Syrups (AREA)
HK00100533A 1996-07-03 2000-01-28 Granulate for the preparation of fast-disintegrating and fast-dissolving compositions containing a high amount of drug HK1021511A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP96201829 1996-07-03
US08/770,421 US5837292A (en) 1996-07-03 1996-12-20 Granulate for the preparation of fast-disintegrating and fast-dissolving compositions containing a high amount of drug
PCT/EP1997/003250 WO1998001114A1 (fr) 1996-07-03 1997-06-19 Granules destines a la preparation de compositions a haut pouvoir de desintegration et de dissolution, a teneur elevee en medicament

Publications (1)

Publication Number Publication Date
HK1021511A1 true HK1021511A1 (en) 2000-06-16

Family

ID=8224133

Family Applications (1)

Application Number Title Priority Date Filing Date
HK00100533A HK1021511A1 (en) 1996-07-03 2000-01-28 Granulate for the preparation of fast-disintegrating and fast-dissolving compositions containing a high amount of drug

Country Status (36)

Country Link
US (1) US5837292A (fr)
EP (1) EP0910344B1 (fr)
JP (1) JP4159607B2 (fr)
CN (1) CN1131025C (fr)
AR (1) AR008252A1 (fr)
AT (1) ATE237314T1 (fr)
AU (1) AU731276B2 (fr)
BG (1) BG64114B1 (fr)
BR (1) BR9710181B1 (fr)
CA (1) CA2258841C (fr)
CO (1) CO4890859A1 (fr)
CZ (1) CZ295893B6 (fr)
DE (1) DE69720995T2 (fr)
DK (1) DK0910344T3 (fr)
EA (1) EA001537B1 (fr)
EG (1) EG23814A (fr)
ES (1) ES2197351T3 (fr)
HK (1) HK1021511A1 (fr)
HU (1) HU225115B1 (fr)
ID (1) ID17128A (fr)
IL (1) IL127364A (fr)
JO (1) JO1969B1 (fr)
MY (1) MY116124A (fr)
NO (1) NO320767B1 (fr)
NZ (1) NZ333247A (fr)
PE (1) PE89798A1 (fr)
PL (1) PL188235B1 (fr)
PT (1) PT910344E (fr)
SI (1) SI0910344T1 (fr)
SK (1) SK284175B6 (fr)
TN (1) TNSN97114A1 (fr)
TR (1) TR199802762T2 (fr)
TW (1) TW473392B (fr)
UA (1) UA61917C2 (fr)
WO (1) WO1998001114A1 (fr)
ZA (1) ZA975848B (fr)

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BR9910481A (pt) * 1998-06-11 2001-01-09 Upjohn Co Composição farmacêutica para comprimido de liberação não-contìnua
IT1305308B1 (it) * 1999-03-26 2001-05-04 Biosint S P A Granulato ad alto contenuto di l-carnitina o alcanoil-l-carnitina,particolarmente adatto alla produzione di compresse per compressione
AU4441899A (en) * 1999-05-14 2000-12-05 Eli Lilly And Company Process for preparing pharmaceutical bulk material having uniform dissolution
HU227070B1 (en) * 1999-08-11 2010-06-28 Egis Gyogyszergyar Nyilvanosan Immediate release pharmaceutical composition containing ciprofloxacin and process for its production
AR028253A1 (es) * 2000-03-16 2003-04-30 Pfizer Prod Inc Inhibidores de la glucogeno fosforilasa
FR2816507B1 (fr) * 2000-11-16 2003-02-28 Ethypharm Lab Prod Ethiques Microgranules a base de principe actif, procede de fabrication et compositons pharmaceutiques integrant lesdits microgranules
US6733781B2 (en) 2000-12-06 2004-05-11 Wyeth Fast dissolving tablet
US7799342B2 (en) * 2000-12-06 2010-09-21 Wyeth Llc Fast dissolving tablet
HUP0303178A3 (en) * 2001-02-05 2008-03-28 R P Scherer Technologies Methods and compositions for reducing the taste of pharmaceutically active agents
EP1285649A1 (fr) * 2001-08-23 2003-02-26 Cimex AG Comprimé dispersible à deux couches comprenant de l'amoxicilline et du clavulanate dans des couches séparées
RU2004123621A (ru) * 2002-02-01 2005-04-10 Пфайзер Продактс Инк. (Us) Лекарственные формы с немедленным высвобождением, содержащие твердые дисперсии лекарств
US20030229101A1 (en) * 2002-06-06 2003-12-11 Sherman Bernard Charles Tablets comprising ciprofloxacin hydrochloride
KR20050062514A (ko) * 2002-07-16 2005-06-23 랜박시 래보러터리스 리미티드 경구 투여용 분산성 정제
AU2003247023A1 (en) * 2002-08-02 2004-02-25 Ranbaxy Laboratories Limited A process for the preparation of dispersible tablet of cephalexin
JP4702763B2 (ja) * 2003-07-30 2011-06-15 塩野義製薬株式会社 結晶セルロースを含有する安定な錠剤
US7838029B1 (en) * 2003-07-31 2010-11-23 Watson Laboratories, Inc. Mirtazapine solid dosage forms
US7390503B1 (en) 2003-08-22 2008-06-24 Barr Laboratories, Inc. Ondansetron orally disintegrating tablets
PL3395338T3 (pl) * 2003-09-12 2019-10-31 Amgen Inc Szybko rozpuszczająca się formulacja zawierająca cynakalcet HCl
US20050089558A1 (en) * 2003-10-28 2005-04-28 Alamo Pharmaceuticals, Llc Compositions and methods for the co-formulation and administration of tramadol and propoxyphene
EP1681050A1 (fr) * 2005-01-13 2006-07-19 Strides Arcolab Limited Composition pharmaceutique dispersible avec libération prolongée
US7811604B1 (en) 2005-11-14 2010-10-12 Barr Laboratories, Inc. Non-effervescent, orally disintegrating solid pharmaceutical dosage forms comprising clozapine and methods of making and using the same
US8617597B2 (en) 2006-07-06 2013-12-31 Bayer Intellectual Property Gmbh Pharmaceutical composition containing a tetrahydrofolic acid
WO2008008120A1 (fr) * 2006-07-14 2008-01-17 Fmc Corporation Forme solide
JP5201819B2 (ja) * 2006-11-22 2013-06-05 エスエス製薬株式会社 固形組成物
US20080311162A1 (en) * 2007-05-16 2008-12-18 Olivia Darmuzey Solid form
JP5637624B2 (ja) * 2009-02-12 2014-12-10 富士化学工業株式会社 崩壊性粒子組成物及びそれを用いた速崩壊性圧縮成型物
WO2011152808A1 (fr) * 2010-06-03 2011-12-08 Mahmut Bilgic Formulation comprenant du cefpodoxime proxétil et de l'acide clavulanique
CN101912373B (zh) * 2010-08-24 2012-01-04 北京京丰制药有限公司 稳定的头孢克洛分散片及其制备方法
WO2013151517A1 (fr) * 2012-04-04 2013-10-10 Mahmut Bilgic Formulations en comprimés comprenant du cefpodoxime proxétil et de l'acide clavulanique
JP2015063521A (ja) * 2013-09-02 2015-04-09 科研製薬株式会社 高い薬物含有率を有する錠剤及びその製造方法
CN106255512B (zh) 2014-04-21 2021-01-01 株式会社大赛璐 含有微小纤维状纤维素的崩解性颗粒组合物
CN110051639B (zh) * 2019-03-15 2021-08-31 河北嘉迈医药科技有限公司 一种快速崩解型尼麦角林片及其制备方法
CN117683469A (zh) * 2023-10-24 2024-03-12 绍兴拓邦新能源股份有限公司 一种晶硅片背面碱抛光固态添加剂及其制备方法

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BE795766A (fr) * 1972-02-22 1973-08-22 Lilly Co Eli Particules de napsylate de propoxyphene retard et procede de fabrication de ces particules
DE2259646C2 (de) * 1972-12-06 1984-11-22 Hoechst Ag, 6230 Frankfurt Hochdosierte Tabletten von Cephalosporin-Derivaten sowie Verfahren zu ihrer Herstellung
GB1509866A (en) * 1975-06-10 1978-05-04 Johnson & Johnson Enteric coated digestive enzyme compositions
JPS58403B2 (ja) * 1975-07-24 1983-01-06 武田薬品工業株式会社 Ｌ− アスコルビンサンセイザイノ セイゾウホウ
NL184308C (nl) * 1975-07-24 1989-06-16 Takeda Chemical Industries Ltd Werkwijze voor het bereiden van l-ascorbienzuurgranules.
GB1560475A (en) * 1975-10-11 1980-02-06 Lilly Industries Ltd Pharmaceutical formulation
GB1561301A (en) * 1976-01-02 1980-02-20 Beecham Group Ltd Orally administrable pharmaceutical composition
HU187215B (en) * 1983-01-26 1985-11-28 Egyt Gyogyszervegyeszeti Gyar Method for producing pharmaceutical product of high actor content and prolonged effect
EP0200252B1 (fr) * 1985-05-02 1999-03-10 Yamanouchi Europe B.V. Comprimés contenant de la triméthoprime et un sulfonamide
GB8521350D0 (en) * 1985-08-28 1985-10-02 Euro Celtique Sa Analgesic composition
DE3887179T2 (de) * 1987-03-02 1994-06-16 Brocades Pharma Bv Pharmazeutische Zusammensetzung, pharmazeutisches Granulat und Verfahren zu ihrer Herstellung.
EP0330284B1 (fr) * 1988-02-25 1994-07-27 Yamanouchi Europe B.V. Procédé de préparation d'un granulé pharmaceutique
US4911921A (en) * 1989-02-02 1990-03-27 Mallinckrodt, Inc. High ibuprofen content granulations
GB9109862D0 (en) * 1991-05-08 1991-07-03 Beecham Lab Sa Pharmaceutical formulations
DE4122217C2 (de) * 1991-07-04 1997-02-13 Merz & Co Gmbh & Co Verfahren zur Herstellung mechanisch stabiler, gut zerfallender Komprimate aus kleinen wirkstoffhaltigen Formkörpern
IL109097A0 (en) * 1993-04-03 1994-06-24 Knoll Ag Delayed release micro tablet of beta-phenylpropiophenone derivatives and its production

Also Published As

Publication number Publication date
CO4890859A1 (es) 2000-02-28
TR199802762T2 (xx) 1999-03-22
ES2197351T3 (es) 2004-01-01
PL330958A1 (en) 1999-06-21
HUP9903308A2 (hu) 2000-03-28
EA001537B1 (ru) 2001-04-23
DK0910344T3 (da) 2003-07-07
JO1969B1 (en) 1997-12-15
IL127364A (en) 2003-04-10
PL188235B1 (pl) 2004-12-31
CZ699A3 (cs) 1999-04-14
ZA975848B (en) 1999-04-12
MY116124A (en) 2003-11-28
CA2258841C (fr) 2006-05-30
BR9710181B1 (pt) 2009-08-11
JP2000513727A (ja) 2000-10-17
JP4159607B2 (ja) 2008-10-01
IL127364A0 (en) 1999-10-28
NO986157L (no) 1999-02-01
WO1998001114A1 (fr) 1998-01-15
BG103047A (en) 1999-07-30
EA199900075A1 (ru) 1999-06-24
PT910344E (pt) 2003-09-30
AU731276B2 (en) 2001-03-29
EP0910344A1 (fr) 1999-04-28
EG23814A (en) 2007-09-12
BG64114B1 (bg) 2004-01-30
SI0910344T1 (en) 2003-08-31
ATE237314T1 (de) 2003-05-15
CA2258841A1 (fr) 1998-01-15
DE69720995T2 (de) 2003-11-13
NO320767B1 (no) 2006-01-23
AU3342197A (en) 1998-02-02
SK284175B6 (sk) 2004-10-05
CN1131025C (zh) 2003-12-17
AR008252A1 (es) 1999-12-29
CN1224348A (zh) 1999-07-28
TNSN97114A1 (fr) 2005-03-15
NO986157D0 (no) 1998-12-28
CZ295893B6 (cs) 2005-11-16
UA61917C2 (uk) 2003-12-15
TW473392B (en) 2002-01-21
NZ333247A (en) 2000-07-28
HU225115B1 (hu) 2006-06-28
DE69720995D1 (de) 2003-05-22
EP0910344B1 (fr) 2003-04-16
PE89798A1 (es) 1999-01-12
BR9710181A (pt) 1999-08-10
HUP9903308A3 (en) 2001-03-28
US5837292A (en) 1998-11-17
SK176798A3 (en) 2000-04-10
ID17128A (id) 1997-12-04

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Legal Events

Date Code Title Description
PF Patent in force
PE Patent expired

Effective date: 20170618