HK101086A - 9-aminoalkylfluorenes,process therefor and antiarrhythmic formulations thereof - Google Patents

9-aminoalkylfluorenes,process therefor and antiarrhythmic formulations thereof

Info

Publication number
HK101086A
HK101086A HK1010/86A HK101086A HK101086A HK 101086 A HK101086 A HK 101086A HK 1010/86 A HK1010/86 A HK 1010/86A HK 101086 A HK101086 A HK 101086A HK 101086 A HK101086 A HK 101086A
Authority
HK
Hong Kong
Prior art keywords
aminoalkylfluorenes
antiarrhythmic
formulations
process therefor
therefor
Prior art date
Application number
HK1010/86A
Other languages
English (en)
Inventor
William Bryant Lacefield
Richard Lee Simon
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of HK101086A publication Critical patent/HK101086A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A41—WEARING APPAREL
    • A41D—OUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
    • A41D31/00—Materials specially adapted for outerwear
    • A41D31/04—Materials specially adapted for outerwear characterised by special function or use
    • A41D31/10—Impermeable to liquids, e.g. waterproof; Liquid-repellent
    • A41D31/102—Waterproof and breathable
    • A—HUMAN NECESSITIES
    • A41—WEARING APPAREL
    • A41D—OUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
    • A41D31/00—Materials specially adapted for outerwear
    • A41D31/04—Materials specially adapted for outerwear characterised by special function or use
    • A41D31/18—Elastic
    • A41D31/185—Elastic using layered materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18—Fluorenes; Hydrogenated fluorenes

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Textile Engineering (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK1010/86A 1979-03-12 1986-12-24 9-aminoalkylfluorenes,process therefor and antiarrhythmic formulations thereof HK101086A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1953379A 1979-03-12 1979-03-12

Publications (1)

Publication Number Publication Date
HK101086A true HK101086A (en) 1987-01-02

Family

ID=21793707

Family Applications (1)

Application Number Title Priority Date Filing Date
HK1010/86A HK101086A (en) 1979-03-12 1986-12-24 9-aminoalkylfluorenes,process therefor and antiarrhythmic formulations thereof

Country Status (40)

Country Link
US (1) US4277495A (ko)
EP (1) EP0018076B1 (ko)
JP (1) JPS55124743A (ko)
KR (2) KR840000279B1 (ko)
AR (6) AR228851A1 (ko)
AT (4) AT370407B (ko)
AU (1) AU527992B2 (ko)
BE (1) BE882166A (ko)
CA (1) CA1136624A (ko)
CH (1) CH643234A5 (ko)
CS (4) CS214700B2 (ko)
CY (1) CY1345A (ko)
DD (1) DD149511A5 (ko)
DE (1) DE3064872D1 (ko)
DK (1) DK158658C (ko)
EG (1) EG14592A (ko)
ES (5) ES489470A0 (ko)
FI (3) FI67211C (ko)
FR (2) FR2460287A1 (ko)
GB (1) GB2046257B (ko)
GR (1) GR68035B (ko)
GT (1) GT198062477A (ko)
HK (1) HK101086A (ko)
HU (1) HU179837B (ko)
IE (1) IE49553B1 (ko)
IL (1) IL59558A (ko)
IT (1) IT1140772B (ko)
LU (1) LU82236A1 (ko)
MA (1) MA18763A1 (ko)
MY (1) MY8700080A (ko)
NZ (1) NZ193078A (ko)
OA (1) OA06486A (ko)
PH (1) PH15594A (ko)
PL (1) PL122643B1 (ko)
PT (1) PT70927A (ko)
RO (2) RO79822A (ko)
SG (1) SG72286G (ko)
SU (2) SU1022656A3 (ko)
YU (1) YU65680A (ko)
ZA (1) ZA801422B (ko)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4212337A (en) * 1978-03-31 1980-07-15 Union Carbide Corporation Closure fastening device
US4452745A (en) * 1981-02-06 1984-06-05 Eli Lilly And Company 9-Aminoalkylfluorenes
US4484352A (en) * 1983-02-07 1984-11-20 Katzin Lawrence F Reclosable plastic bag
US4552982A (en) * 1983-08-01 1985-11-12 Eli Lilly And Company Synthesis of 9-carbamoyl-9-(3-aminopropyl)fluorenes
US4508735A (en) * 1983-09-21 1985-04-02 Eli Lilly And Company Anti-arrhythmic N-alkanoylaminoalkyl fluorenes
GR80674B (en) * 1983-10-19 1985-02-18 Lilly Co Eli Process for producing 9-carbamoyl fluorene derivatives
US4486592A (en) * 1983-10-19 1984-12-04 Eli Lilly And Company 9-Carbamoylfluorene derivatives
US4585894A (en) * 1983-10-19 1986-04-29 Eli Lilly And Company Process for producing 9-carbamoyl fluorene derivatives
DE3444837A1 (de) * 1984-12-08 1986-06-12 Basf Ag, 6700 Ludwigshafen 10,11-dihydro-5h-dibenzo(a,d)cycloheptadien- derivate, ihre herstellung und verwendung
GB9304189D0 (en) * 1993-03-02 1993-04-21 Sturmey Archer Ltd Epicyclic change speed gear hubs
US5739135A (en) * 1993-09-03 1998-04-14 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
US5631203A (en) * 1995-05-04 1997-05-20 Phillips Petroleum Company Metallocene compounds and preparation thereof containing terminal alkynes
DE69728762T2 (de) * 1996-01-16 2005-03-31 Bristol-Myers Squibb Co. Konformationseingeschränkte aromatische inhibitoren des microsomalen triglyceridtransferproteins und verfahren
US5760246A (en) 1996-12-17 1998-06-02 Biller; Scott A. Conformationally restricted aromatic inhibitors of microsomal triglyceride transfer protein and method

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB736372A (en) * 1953-05-06 1955-09-07 Miles Lab Fluorene derivatives
NL287095A (ko) 1962-12-21 1965-02-25
FR1345419A (fr) * 1962-12-21 1963-12-06 Boehringer & Soehne Gmbh Procédé pour la préparation de dérivés basiques du fluorène et des sels de ces dérivés
DE1203253B (de) * 1963-02-09 1965-10-21 Boehringer & Soehne Gmbh Verfahren zur Herstellung basischer Fluorenderivate und ihrer Salze
FR1482727A (fr) * 1965-06-10 1967-05-26 Upjohn Co 9-(2-amino-1-méthyléthyl) fluoren-9-ols et leur procédé de fabrication
GB1211459A (en) * 1967-05-10 1970-11-04 Abbott Lab Hydroxy amines
US3660485A (en) * 1970-10-05 1972-05-02 Searle & Co Fluorene-9-carboxylic acid hydrazides
US3843657A (en) * 1972-12-08 1974-10-22 Searle & Co 9-dialkylamin oalkyl-n-substituted fluorene-9-carboxamides

Also Published As

Publication number Publication date
FI840921A (fi) 1984-03-07
HU179837B (en) 1982-12-28
IL59558A (en) 1984-05-31
AR230983A1 (es) 1984-08-31
DD149511A5 (de) 1981-07-15
CS214696B2 (en) 1982-05-28
JPS55124743A (en) 1980-09-26
RO79822A (ro) 1983-02-01
ATA114181A (de) 1982-01-15
AU527992B2 (en) 1983-03-31
FR2457278B1 (ko) 1984-06-29
YU65680A (en) 1983-02-28
ZA801422B (en) 1981-10-28
AT368125B (de) 1982-09-10
AR229402A1 (es) 1983-08-15
ES8201943A1 (es) 1982-01-01
FI840921A0 (fi) 1984-03-07
AT370407B (de) 1983-03-25
ES8201946A1 (es) 1982-01-01
FI69299C (fi) 1986-01-10
AU5630180A (en) 1980-09-18
RO85074A (ro) 1984-08-17
EP0018076B1 (en) 1983-09-21
CY1345A (en) 1987-01-16
ES8104186A1 (es) 1981-04-16
MA18763A1 (fr) 1980-10-01
FR2460287A1 (fr) 1981-01-23
PH15594A (en) 1983-02-28
ES497303A0 (es) 1982-01-01
ATA113981A (de) 1982-01-15
PT70927A (en) 1980-04-01
US4277495A (en) 1981-07-07
JPS6314702B2 (ko) 1988-04-01
IE49553B1 (en) 1985-10-30
ES497302A0 (es) 1982-01-01
ES497301A0 (es) 1982-01-01
AT368130B (de) 1982-09-10
OA06486A (fr) 1981-07-31
FR2460287B1 (ko) 1983-03-11
GR68035B (ko) 1981-10-27
PL122643B1 (en) 1982-08-31
ATA134480A (de) 1982-08-15
FI800735A (fi) 1980-09-13
SU1022656A3 (ru) 1983-06-07
KR840000279B1 (ko) 1984-03-13
MY8700080A (en) 1987-12-31
GT198062477A (es) 1981-09-02
IT8020502A0 (it) 1980-03-11
EP0018076A1 (en) 1980-10-29
DE3064872D1 (en) 1983-10-27
ES8201947A1 (es) 1982-01-01
ATA114081A (de) 1982-01-15
AR227318A1 (es) 1982-10-15
EG14592A (en) 1985-03-31
LU82236A1 (fr) 1980-06-06
CS214699B2 (en) 1982-05-28
FI840920A0 (fi) 1984-03-07
DK158658B (da) 1990-07-02
CS214700B2 (en) 1982-05-28
FI69299B (fi) 1985-09-30
AR228059A1 (es) 1983-01-14
IT1140772B (it) 1986-10-10
AR225526A1 (es) 1982-03-31
DK158658C (da) 1990-12-31
FI67211C (fi) 1985-02-11
IE800494L (en) 1980-09-12
GB2046257A (en) 1980-11-12
FI70006C (fi) 1986-09-12
ES8201945A1 (es) 1982-01-01
CA1136624A (en) 1982-11-30
KR840001836B1 (ko) 1984-10-22
KR830001860A (ko) 1983-05-19
CS214698B2 (en) 1982-05-28
GB2046257B (en) 1983-10-19
CH643234A5 (fr) 1984-05-30
BE882166A (fr) 1980-09-11
SU1015820A3 (ru) 1983-04-30
AT368131B (de) 1982-09-10
DK103380A (da) 1980-09-13
SG72286G (en) 1987-03-27
ES497300A0 (es) 1982-01-01
FI840920A (fi) 1984-03-07
IL59558A0 (en) 1980-06-30
NZ193078A (en) 1981-11-19
FI67211B (fi) 1984-10-31
FR2457278A1 (fr) 1980-12-19
ES489470A0 (es) 1981-04-16
PL222600A1 (ko) 1980-12-15
FI70006B (fi) 1986-01-31
AR228851A1 (es) 1983-04-29

Similar Documents

Publication Publication Date Title
GB2064520B (en) A-aryl-1h-1,2,4-triazole-1-ethanols
DE3065143D1 (en) Phosphor and process for preparing the same
DE3071484D1 (en) Linear polychlorophosphazenes, process for their preparation and their use
DE3064872D1 (en) 9-aminoalkylfluorenes, process therefor and antiarrhythmic formulations thereof
DE3065163D1 (en) New 4-fluoro-3-phenoxy-benzyl-ethers, process for their preparation and their use
DE3066702D1 (en) 2.5-diketopiperazine-derivative, process for its preparation and its use
GB2058767B (en) 4'-substituted-4,5',8-trialklpsoralens
GB2044770B (en) 24,24 - difluoro- 25 - hydroxycholecalciferol
DE2961268D1 (en) Bicyclo-compounds, processes for their preparation and their application
DE2965252D1 (en) Monoazo-compounds, process for their preparation and their use
DE3062050D1 (en) Gelatins, process for their preparation and their use
PH17758A (en) Thiazolinoazetidinones and process therefor
ZA786075B (en) 13,14-didehydro-protaglandins and process for their preparation
GB2075982B (en) 1-3-dihydroxy-27-nor-cholesta-5-en and 5,7-dien-25-one
PH14749A (en) 1,1-biphenyl-2-yl propyl and butyl amines,formulations and antiarrhythmic treatment
IL75705A (en) 1,2,5-thiadiazole-1-oxides
ZA804183B (en) 1,2,4-thiadiazolyloxyphenylureas
GB2042549B (en) 25 - hydroxy-cholecalciferol - 26,23 - lactone
CS744680A2 (en) Mechanismus pro membranovou spojku, zejmena pro automobilni vozidla
NZ194583A (en) 5,6-dihydro-11h-pyrimido (4,5-6)(1,5) benzodiazepin-5-ones
DE2963118D1 (en) 3,3-bisfluoromethyl-butan-2-one and process for its preparation
GB2040932B (en) 1 - substituted - 3,4 - epoxypyrrolidines
CS515881A2 (en) Zpusob pripravy oktahydropyrazolo(3,4 g) chinolinu
GB2118169B (en) 1,1,1-trichlorotriacontane
GB2051807B (en) Oxazolinoazetidinones and process therefor