GB2605883B - Tumor infiltrating lymphocytes and methods of therapy - Google Patents

Tumor infiltrating lymphocytes and methods of therapy Download PDF

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Publication number
GB2605883B
GB2605883B GB2205417.5A GB202205417A GB2605883B GB 2605883 B GB2605883 B GB 2605883B GB 202205417 A GB202205417 A GB 202205417A GB 2605883 B GB2605883 B GB 2605883B
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Prior art keywords
therapy
methods
tumor infiltrating
infiltrating lymphocytes
lymphocytes
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Active
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GB2205417.5A
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GB202205417D0 (en
GB2605883A (en
Inventor
Moriarity Branden
Webber Beau
Choudhry Modassir
A Rosenberg Steven
C Palmer Douglas
P Restifo Nicholas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Minnesota Twin Cities
Intima Bioscience Inc
University of Minnesota System
US Department of Health and Human Services
Original Assignee
University of Minnesota Twin Cities
Intima Bioscience Inc
University of Minnesota System
US Department of Health and Human Services
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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GB2205417.5A 2016-10-18 2017-10-18 Tumor infiltrating lymphocytes and methods of therapy Active GB2605883B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662409651P 2016-10-18 2016-10-18
US201762452244P 2017-01-30 2017-01-30
GB2113770.8A GB2604416B (en) 2016-10-18 2017-10-18 Tumor infiltating lymphocytes and methods of therapy

Publications (3)

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GB202205417D0 GB202205417D0 (en) 2022-05-25
GB2605883A GB2605883A (en) 2022-10-19
GB2605883B true GB2605883B (en) 2023-03-15

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GB2209032.8A Active GB2605540B (en) 2016-10-18 2017-10-18 Tumor infiltrating lymphocytes and methods of therapy
GB2113770.8A Active GB2604416B (en) 2016-10-18 2017-10-18 Tumor infiltating lymphocytes and methods of therapy
GB2205417.5A Active GB2605883B (en) 2016-10-18 2017-10-18 Tumor infiltrating lymphocytes and methods of therapy
GB1906855.0A Active GB2573406B (en) 2016-10-18 2017-10-18 Tumor infiltrating lymphocytes and methods of therapy

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US (5) US10912797B2 (enExample)
EP (2) EP4338799A3 (enExample)
JP (3) JP7181862B2 (enExample)
CN (1) CN110520530A (enExample)
AU (2) AU2017346885B2 (enExample)
CA (1) CA3041068A1 (enExample)
GB (4) GB2605540B (enExample)
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