GB201403684D0 - Vector - Google Patents

Vector

Info

Publication number
GB201403684D0
GB201403684D0 GBGB1403684.2A GB201403684A GB201403684D0 GB 201403684 D0 GB201403684 D0 GB 201403684D0 GB 201403684 A GB201403684 A GB 201403684A GB 201403684 D0 GB201403684 D0 GB 201403684D0
Authority
GB
United Kingdom
Prior art keywords
vector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1403684.2A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kings College London
Original Assignee
Kings College London
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50490674&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GB201403684(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kings College London filed Critical Kings College London
Priority to GBGB1403684.2A priority Critical patent/GB201403684D0/en
Publication of GB201403684D0 publication Critical patent/GB201403684D0/en
Priority to KR1020167022254A priority patent/KR102082032B1/ko
Priority to EP19188703.3A priority patent/EP3597760A3/en
Priority to ES15705974T priority patent/ES2749235T3/es
Priority to CA3126061A priority patent/CA3126061C/en
Priority to SG11201606365TA priority patent/SG11201606365TA/en
Priority to MX2016010649A priority patent/MX372992B/es
Priority to US15/570,687 priority patent/US20180135076A1/en
Priority to HUE15705974A priority patent/HUE045801T2/hu
Priority to SI201530969T priority patent/SI3108000T1/sl
Priority to EP15705974.2A priority patent/EP3108000B1/en
Priority to JP2016569022A priority patent/JP6602788B2/ja
Priority to DK15705974T priority patent/DK3108000T3/da
Priority to CN201580008760.XA priority patent/CN106062200B/zh
Priority to PCT/EP2015/053335 priority patent/WO2015121501A1/en
Priority to BR112016018598A priority patent/BR112016018598A2/pt
Priority to RU2016133623A priority patent/RU2743382C2/ru
Priority to CA2939612A priority patent/CA2939612C/en
Priority to AU2015216847A priority patent/AU2015216847B2/en
Priority to PL15705974T priority patent/PL3108000T3/pl
Priority to PT157059742T priority patent/PT3108000T/pt
Priority to IL247332A priority patent/IL247332B/en
Priority to JP2019186201A priority patent/JP6942166B2/ja
Priority to US17/072,676 priority patent/US11802293B2/en
Priority to IL279154A priority patent/IL279154B/en
Priority to RU2021102290A priority patent/RU2846967C2/ru
Priority to AU2021202538A priority patent/AU2021202538B2/en
Priority to JP2021086867A priority patent/JP7309780B2/ja
Priority to US17/466,237 priority patent/US20220106612A1/en
Priority to JP2023109822A priority patent/JP7612767B2/ja
Priority to US18/487,398 priority patent/US20240124894A1/en
Priority to AU2023258448A priority patent/AU2023258448A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C12N15/861—Adenoviral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14132—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14142—Use of virus, viral particle or viral elements as a vector virus or viral particle as vehicle, e.g. encapsulating small organic molecule
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GBGB1403684.2A 2014-02-17 2014-03-03 Vector Ceased GB201403684D0 (en)

Priority Applications (32)

Application Number Priority Date Filing Date Title
GBGB1403684.2A GB201403684D0 (en) 2014-03-03 2014-03-03 Vector
PL15705974T PL3108000T3 (pl) 2014-02-17 2015-02-17 Wektor oparty na wirusie satelitarnym adenowirusa
PT157059742T PT3108000T (pt) 2014-02-17 2015-02-17 Vetor de vírus adeno-associado.
BR112016018598A BR112016018598A2 (pt) 2014-02-17 2015-02-17 vetor de vírus adeno-associados
RU2016133623A RU2743382C2 (ru) 2014-02-17 2015-02-17 Вектор аденоассоциированного вируса
ES15705974T ES2749235T3 (es) 2014-02-17 2015-02-17 Vector de virus adenoasociado
CA3126061A CA3126061C (en) 2014-02-17 2015-02-17 Adeno-associated virus vector
SG11201606365TA SG11201606365TA (en) 2014-02-17 2015-02-17 Adeno-associated virus vector
MX2016010649A MX372992B (es) 2014-02-17 2015-02-17 Vector de virus adeno-asociado.
US15/570,687 US20180135076A1 (en) 2014-02-17 2015-02-17 Adeno-associated virus vector
HUE15705974A HUE045801T2 (hu) 2014-02-17 2015-02-17 Adeno-asszociált vírus vektor
SI201530969T SI3108000T1 (sl) 2014-02-17 2015-02-17 Vektor adeno-pridruženega virusa
EP15705974.2A EP3108000B1 (en) 2014-02-17 2015-02-17 Adeno-associated virus vector
JP2016569022A JP6602788B2 (ja) 2014-02-17 2015-02-17 アデノ随伴ウイルスベクター
DK15705974T DK3108000T3 (da) 2014-02-17 2015-02-17 Adeno-associeret virusvektor
CN201580008760.XA CN106062200B (zh) 2014-02-17 2015-02-17 腺相关病毒载体
PCT/EP2015/053335 WO2015121501A1 (en) 2014-02-17 2015-02-17 Adeno-associated virus vector
KR1020167022254A KR102082032B1 (ko) 2014-02-17 2015-02-17 아데노-관련 바이러스 벡터
EP19188703.3A EP3597760A3 (en) 2014-02-17 2015-02-17 Adeno-associated virus vector
CA2939612A CA2939612C (en) 2014-02-17 2015-02-17 Adeno-associated virus vector
AU2015216847A AU2015216847B2 (en) 2014-02-17 2015-02-17 Adeno-associated virus vector
IL247332A IL247332B (en) 2014-02-17 2016-08-17 Adenovirus-related vector
JP2019186201A JP6942166B2 (ja) 2014-02-17 2019-10-09 アデノ随伴ウイルスベクター
US17/072,676 US11802293B2 (en) 2014-02-17 2020-10-16 Adeno-associated virus vector
IL279154A IL279154B (en) 2014-02-17 2020-12-02 Adenovirus-related vector
RU2021102290A RU2846967C2 (ru) 2014-02-17 2021-02-02 Вектор аденоассоциированного вируса
AU2021202538A AU2021202538B2 (en) 2014-02-17 2021-04-26 Adeno-associated virus vector
JP2021086867A JP7309780B2 (ja) 2014-02-17 2021-05-24 アデノ随伴ウイルスベクター
US17/466,237 US20220106612A1 (en) 2014-02-17 2021-09-03 Adeno-associated virus vector
JP2023109822A JP7612767B2 (ja) 2014-02-17 2023-07-04 アデノ随伴ウイルスベクター
US18/487,398 US20240124894A1 (en) 2014-02-17 2023-10-16 Adeno-associated virus vector
AU2023258448A AU2023258448A1 (en) 2014-02-17 2023-11-03 Adeno-associated virus vector

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1403684.2A GB201403684D0 (en) 2014-03-03 2014-03-03 Vector

Publications (1)

Publication Number Publication Date
GB201403684D0 true GB201403684D0 (en) 2014-04-16

Family

ID=50490674

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1403684.2A Ceased GB201403684D0 (en) 2014-02-17 2014-03-03 Vector

Country Status (20)

Country Link
US (4) US20180135076A1 (OSRAM)
EP (2) EP3597760A3 (OSRAM)
JP (4) JP6602788B2 (OSRAM)
KR (1) KR102082032B1 (OSRAM)
CN (1) CN106062200B (OSRAM)
AU (3) AU2015216847B2 (OSRAM)
BR (1) BR112016018598A2 (OSRAM)
CA (2) CA3126061C (OSRAM)
DK (1) DK3108000T3 (OSRAM)
ES (1) ES2749235T3 (OSRAM)
GB (1) GB201403684D0 (OSRAM)
HU (1) HUE045801T2 (OSRAM)
IL (2) IL247332B (OSRAM)
MX (1) MX372992B (OSRAM)
PL (1) PL3108000T3 (OSRAM)
PT (1) PT3108000T (OSRAM)
RU (1) RU2743382C2 (OSRAM)
SG (1) SG11201606365TA (OSRAM)
SI (1) SI3108000T1 (OSRAM)
WO (1) WO2015121501A1 (OSRAM)

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* Cited by examiner, † Cited by third party
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WO2010138263A2 (en) 2009-05-28 2010-12-02 University Of Massachusetts Novel aav 's and uses thereof
CA2833905C (en) 2010-04-23 2019-09-10 University Of Massachusetts Multicistronic expression constructs
EP3540055A1 (en) 2010-04-23 2019-09-18 University of Massachusetts Cns targeting aav vectors and methods of use thereof
EP2986635B1 (en) 2013-04-18 2018-10-03 Fondazione Telethon Effective delivery of large genes by dual aav vectors
WO2014194132A1 (en) 2013-05-31 2014-12-04 The Regents Of The University Of California Adeno-associated virus variants and methods of use thereof
EP3633041A3 (en) 2013-09-26 2020-07-29 University of Florida Research Foundation, Inc. Synthetic combinatorial aav capsid library for targeted gene therapy
GB201403684D0 (en) * 2014-03-03 2014-04-16 King S College London Vector
WO2015127128A2 (en) 2014-02-19 2015-08-27 University Of Massachusetts Recombinant aavs having useful transcytosis properties
JP6756700B2 (ja) 2014-03-18 2020-09-16 ユニバーシティ オブ マサチューセッツ 筋萎縮性側索硬化症を処置するためのｒＡＡＶベースの組成物および方法
EP3134522B1 (en) 2014-04-25 2021-10-06 University of Massachusetts Recombinant aav vectors useful for reducing immunity against transgene products
LT3137497T (lt) * 2014-05-02 2021-07-26 Genzyme Corporation Aav vektoriai, skirti tinklainės ir cns genų terapijai
US10689653B2 (en) 2014-06-03 2020-06-23 University Of Massachusetts Compositions and methods for modulating dysferlin expression
EP3151866B1 (en) 2014-06-09 2023-03-08 Voyager Therapeutics, Inc. Chimeric capsids
JP6842410B2 (ja) 2014-10-03 2021-03-17 ユニバーシティ オブ マサチューセッツ 新規の高効率ライブラリーにより同定されるａａｖベクター
WO2016054554A1 (en) 2014-10-03 2016-04-07 University Of Massachusetts Heterologous targeting peptide grafted aavs
RU2738421C2 (ru) 2014-10-21 2020-12-14 Юниверсити Оф Массачусетс Варианты рекомбинантных aav и их применения
KR20170096998A (ko) 2014-11-05 2017-08-25 보이저 테라퓨틱스, 인크. 파킨슨병의 치료를 위한 aadc 폴리뉴클레오티드
WO2016077687A1 (en) 2014-11-14 2016-05-19 Voyager Therapeutics, Inc. Compositions and methods of treating amyotrophic lateral sclerosis (als)
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EP3224362B1 (en) * 2014-11-26 2024-09-25 The Regents of The University of California Therapeutic compositions comprising transcription factors and methods of making and using the same
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WO2016131009A1 (en) 2015-02-13 2016-08-18 University Of Massachusetts Compositions and methods for transient delivery of nucleases
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WO2017070516A1 (en) 2015-10-22 2017-04-27 University Of Massachusetts Prostate-targeting adeno-associated virus serotype vectors
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