GB1490306A - 3-amino-indazolecarboxylic acid derivatives process for their preparation and their use as medicaments - Google Patents

3-amino-indazolecarboxylic acid derivatives process for their preparation and their use as medicaments

Info

Publication number
GB1490306A
GB1490306A GB44299/75A GB4429975A GB1490306A GB 1490306 A GB1490306 A GB 1490306A GB 44299/75 A GB44299/75 A GB 44299/75A GB 4429975 A GB4429975 A GB 4429975A GB 1490306 A GB1490306 A GB 1490306A
Authority
GB
United Kingdom
Prior art keywords
amino
formula
compounds
medicaments
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB44299/75A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of GB1490306A publication Critical patent/GB1490306A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56Benzopyrazoles; Hydrogenated benzopyrazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
GB44299/75A 1974-12-13 1975-10-28 3-amino-indazolecarboxylic acid derivatives process for their preparation and their use as medicaments Expired GB1490306A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2458965A DE2458965C3 (de) 1974-12-13 1974-12-13 3-Amino-indazol-N-carbonsäure-Derivate, Verfahren zu ihrer Herstellung sowie sie enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
GB1490306A true GB1490306A (en) 1977-11-02

Family

ID=5933305

Family Applications (1)

Application Number Title Priority Date Filing Date
GB44299/75A Expired GB1490306A (en) 1974-12-13 1975-10-28 3-amino-indazolecarboxylic acid derivatives process for their preparation and their use as medicaments

Country Status (27)

Country Link
US (1) US4051252A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5182266A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) AT343653B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE836528A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1059523A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH622250A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CS (1) CS189731B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DD (1) DD125484A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE2458965C3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK137082C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES443429A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI753493A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2293928A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB1490306A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HK (1) HK52580A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU173557B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE42208B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL48642A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KE (1) KE3078A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
LU (1) LU73993A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL7514521A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO145382C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (1) PL99858B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE419645B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SU (1) SU604487A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
YU (1) YU315275A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA757777B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431657A (en) * 1982-05-24 1984-02-14 Ayerst, Mckenna & Harrison Inc. Analgesic compositions consisting of 2H-benzothieno[3,2-c]pyrazol-3-amine derivatives
KR20010086657A (ko) * 2000-03-02 2001-09-15 성재갑 아미노인다졸 유도체 및 이를 함유하는 싸이클린 의존키나아제 저해제 조성물
KR20030032035A (ko) 2000-09-15 2003-04-23 버텍스 파마슈티칼스 인코포레이티드 단백질 키나제 억제제로서 유용한 피라졸 화합물
US7473691B2 (en) * 2000-09-15 2009-01-06 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
ZA200301701B (en) * 2000-09-15 2004-03-01 Vertex Pharma Pyrazole compounds useful as protein kinase inhibitors.
EP1698627A1 (en) * 2000-09-15 2006-09-06 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
US6660731B2 (en) 2000-09-15 2003-12-09 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
HUP0400908A3 (en) * 2000-12-21 2010-03-29 Vertex Pharma Pyrazole compounds useful as protein kinase inhibitors, their use and pharmaceutical compositions containing them
KR100406634B1 (ko) * 2001-03-12 2003-11-20 주식회사 엘지생명과학 3,5-디아미노인다졸 유도체, 그의 제조방법 및 사이클린의존성 키나아제 저해제로서의 그의 용도
ES2380054T3 (es) 2001-09-26 2012-05-08 Pfizer Italia S.R.L. Derivados de aminoindazol activos como inhibidores de quinasas, procedimientos para su preparación, y composiciones farmacéuticas que los contienen
AU2003215087B2 (en) * 2002-02-06 2009-07-16 Vertex Pharmaceuticals Incorporated Heteroaryl compounds useful as inhibitors of GSK-3
FR2836915B1 (fr) * 2002-03-11 2008-01-11 Aventis Pharma Sa Derives d'aminoindazoles, procede de preparation et intermediaires de ce procede a titre de medicaments et compositions pharmaceutiques les renfermant
ATE468336T1 (de) 2002-03-15 2010-06-15 Vertex Pharma Azolylaminoazine als proteinkinasehemmer
MXPA04011417A (es) 2002-05-17 2005-02-14 Pharmacia Italia Spa Derivados de aminoindazol activos como inhibidores de cinasa, procedimiento para su preparacion y composiciones farmaceuticas que los comprenden.
MY141867A (en) 2002-06-20 2010-07-16 Vertex Pharma Substituted pyrimidines useful as protein kinase inhibitors
BR0313176A (pt) 2002-08-02 2005-06-14 Vertex Pharma Composições de pirazol úteis como inibidores de gsk-3
EP1556053A4 (en) * 2002-10-31 2006-04-19 Amgen Inc ANTI-INFLAMMATORY AGENTS
US7601718B2 (en) 2003-02-06 2009-10-13 Vertex Pharmaceuticals Incorporated Compositions useful as inhibitors of protein kinases
CN1902193B (zh) * 2003-12-04 2011-07-13 沃泰克斯药物股份有限公司 可用作蛋白激酶抑制剂的喹喔啉
DE102004005172A1 (de) 2004-02-02 2005-08-18 Aventis Pharma Deutschland Gmbh Indazolderivate als Inhibitoren der Hormon Sensitiven Lipase
WO2007022384A2 (en) 2005-08-18 2007-02-22 Vertex Pharmaceuticals Incorporated Pyrazine kinase inhibitors
KR20080066069A (ko) * 2005-11-03 2008-07-15 버텍스 파마슈티칼스 인코포레이티드 키나제 억제제로서 유용한 아미노피리미딘
RU2446161C2 (ru) * 2006-04-14 2012-03-27 Эбботт Лэборетриз Способ получения индазолилмочевин, которые подавляют ваниллоидные рецепторы подтипа 1 (vr1)
CA2668429A1 (en) 2006-11-02 2008-05-15 Vertex Pharmaceuticals Incorporated Aminopyridines and aminopyrimidines useful as inhibitors of protein kinases
JP2010513567A (ja) 2006-12-19 2010-04-30 バーテックス ファーマシューティカルズ インコーポレイテッド プロテインキナーゼの阻害剤として有用なアミノピリミジン
ES2435997T3 (es) 2007-03-09 2013-12-26 Vertex Pharmaceuticals, Inc. Aminopirimidinas útiles como inhibidores de las proteínas cinasas
KR20090120510A (ko) 2007-03-09 2009-11-24 버텍스 파마슈티칼스 인코포레이티드 단백질 키나제 억제제로서 유용한 아미노피리미딘
JP2010520887A (ja) 2007-03-09 2010-06-17 バーテックス ファーマシューティカルズ インコーポレイテッド 蛋白キナーゼの阻害剤として有用なアミノピリジン
EP2146982A2 (en) 2007-04-13 2010-01-27 Vertex Pharmaceuticals Incorporated Aminopyrimidines useful as kinase inhibitors
AU2008247594A1 (en) 2007-05-02 2008-11-13 Vertex Pharmaceuticals Incorporated Aminopyrimidines useful as kinase inhibitors
MX2009011811A (es) * 2007-05-02 2010-01-14 Vertex Pharma Aminopirimidinas utiles como inhibidores de cinasa.
NZ580884A (en) * 2007-05-02 2012-02-24 Vertex Pharma Thiazoles and pyrazoles useful as kinase inhibitors
WO2008147626A2 (en) * 2007-05-24 2008-12-04 Vertex Pharmaceuticals Incorporated Thiazoles and pyrazoles useful as kinase inhibitors
TW200916468A (en) 2007-07-31 2009-04-16 Vertex Pharma Process for preparing 5-fluoro-1H-pyrazolo[3,4-b]pyridin-3-amine and derivatives thereof
JP2012501971A (ja) * 2008-09-03 2012-01-26 バーテックス ファーマシューティカルズ インコーポレイテッド 共結晶および共結晶を含む薬学的処方物
DE102009004245A1 (de) 2009-01-09 2010-07-15 Bayer Schering Pharma Aktiengesellschaft Neue anellierte, Heteroatom-verbrückte Pyrazol- und Imidazol-Derivate und ihre Verwendung
BR112015001546B1 (pt) 2012-07-24 2021-02-23 Bial-Portela & Ca, S.A compostos de ureia e sua utilização como inibidores enzimáticos
CN104662002A (zh) * 2012-07-27 2015-05-27 比亚尔-珀特拉和Ca股份公司 取代脲类化合物的合成方法
JP6449277B2 (ja) 2013-07-24 2019-01-09 ビアル−ポルテラ エ コンパニア,ソシエダッド アノニマ イミダゾールカルボキサミドおよびfaah阻害剤としてのそれらの使用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3133081A (en) * 1964-05-12 J-aminoindazole derivatives
CH397698A (de) * 1961-09-08 1965-08-31 Siegfried Ag Verfahren zur Herstellung neuer 1-Carbamyl-indazole
US3274203A (en) * 1963-05-31 1966-09-20 Du Pont 1-carbamyl and thiocarbamyl-3-amino-4-nonsubstituted and substituted pyrazoles
NL6707299A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1966-07-16 1968-01-17
DE1770649A1 (de) * 1968-06-15 1971-11-11 Bayer Ag Substituierte 3-Amino-indazole

Also Published As

Publication number Publication date
KE3078A (en) 1980-10-03
NO145382B (no) 1981-11-30
CA1059523A (en) 1979-07-31
DD125484A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1977-04-20
DK137082B (da) 1978-01-16
FR2293928A1 (fr) 1976-07-09
AT343653B (de) 1978-06-12
ES443429A1 (es) 1977-04-16
ZA757777B (en) 1976-11-24
DE2458965C3 (de) 1979-10-11
IE42208B1 (en) 1980-06-18
IL48642A0 (en) 1976-02-29
ATA939775A (de) 1977-10-15
FI753493A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1976-06-14
NO754024L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1976-06-15
SE419645B (sv) 1981-08-17
LU73993A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1976-11-11
BE836528A (fr) 1976-06-11
SE7513990L (sv) 1976-06-14
FR2293928B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1979-09-21
HK52580A (en) 1980-09-26
NL7514521A (nl) 1976-06-15
DE2458965A1 (de) 1976-06-16
NO145382C (no) 1982-03-10
CS189731B2 (en) 1979-04-30
DK137082C (da) 1978-06-19
PL99858B1 (pl) 1978-08-31
IL48642A (en) 1979-12-30
YU315275A (en) 1982-02-28
DE2458965B2 (de) 1979-02-22
DK567275A (da) 1976-06-14
JPS5182266A (en) 1976-07-19
AU8717075A (en) 1977-06-09
CH622250A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1981-03-31
IE42208L (en) 1976-06-13
HU173557B (hu) 1979-06-28
SU604487A3 (ru) 1978-04-25
US4051252A (en) 1977-09-27

Similar Documents

Publication Publication Date Title
GB1490306A (en) 3-amino-indazolecarboxylic acid derivatives process for their preparation and their use as medicaments
WO2004020430A3 (fr) Derives de dioxane-2-alkylcarbamates, leur preparation et leur application en therapeutique
DK0464465T3 (da) Substituerede aminoalkylbiphenylderivater, antimykotiske præparater indeholdende disse derivater og mellemprodukter til fremstilling deraf
ES438313A1 (es) Un procedimiento para la preparacion de 3-tiometilergolinas.
GB1432816A (en) Pharmaceutical antimycotic compositions medicaments and method
JPS5583749A (en) Quinolone derivative
ES410313A2 (es) Procedimiento para lapreparacion de 6,7-dimetoxi-quinazoli-nonas.
IE38091B1 (en) Process for the manufacture of benzodiazepine derivatives
JPS57183768A (en) 4-methyl-5-(o-carboxyphenyl)carbamoylthiazole derivative and its preparation
ES319653A1 (es) Un procedimiento para la preparacion de derivados de imidazol.
JPS5248669A (en) Preparation of 2,3-dihydropyrane derivatives
GB1447954A (en) Process for the preparation of 1,2,4-triazole derivative
JPS5246071A (en) Imidazole derivatives, fungicides for agriculture and gardening, and p lant growth regulators
IE812941L (en) Imidazole derivatives
JPS5223075A (en) Preparation of pyrazole derivatives
JPS5515455A (en) 2-substituted-methyl-1,4-benzodioxane
JPS5239674A (en) Imidazole derivatives and agricultural bactericides therefrom
ES325546A1 (es) Procedimiento de preparacion de nuevos derivados biologicamente activos de la fenantridona.
JPS52125146A (en) Arylacetylenesulfonamide derivatives and method of preparing the same
JPS5473797A (en) Pyride 3.2.1-jk carbazole derivative
JPS5677265A (en) Novel quinazoline derivative
JPS527956A (en) Succinimide derivatives and its preparation
JPS52113979A (en) Novel 3,4-dihydrocarbostyril derivatives and method preparing the same
JPS53111030A (en) Novel phenylacetic acid derivatives
JPS5271493A (en) Synthesis of pyrrolobenzodiazepins or acid addition salts thereof

Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee