PL99858B1 - Sposob wytwarzania nowych pochodnych kwasu 3-aminoindazolokarboksylowego - Google Patents
Sposob wytwarzania nowych pochodnych kwasu 3-aminoindazolokarboksylowego Download PDFInfo
- Publication number
- PL99858B1 PL99858B1 PL1975185475A PL18547575A PL99858B1 PL 99858 B1 PL99858 B1 PL 99858B1 PL 1975185475 A PL1975185475 A PL 1975185475A PL 18547575 A PL18547575 A PL 18547575A PL 99858 B1 PL99858 B1 PL 99858B1
- Authority
- PL
- Poland
- Prior art keywords
- amino
- formula
- carboxylic acid
- trifluoromethylindazole
- melting point
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2458965A DE2458965C3 (de) | 1974-12-13 | 1974-12-13 | 3-Amino-indazol-N-carbonsäure-Derivate, Verfahren zu ihrer Herstellung sowie sie enthaltende Arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL99858B1 true PL99858B1 (pl) | 1978-08-31 |
Family
ID=5933305
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL1975185475A PL99858B1 (pl) | 1974-12-13 | 1975-12-11 | Sposob wytwarzania nowych pochodnych kwasu 3-aminoindazolokarboksylowego |
Country Status (27)
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4431657A (en) * | 1982-05-24 | 1984-02-14 | Ayerst, Mckenna & Harrison Inc. | Analgesic compositions consisting of 2H-benzothieno[3,2-c]pyrazol-3-amine derivatives |
| KR20010086657A (ko) * | 2000-03-02 | 2001-09-15 | 성재갑 | 아미노인다졸 유도체 및 이를 함유하는 싸이클린 의존키나아제 저해제 조성물 |
| NZ525014A (en) * | 2000-09-15 | 2005-09-30 | Vertex Pharma | Pyrazole compounds useful as protein kinase inhibitors |
| ZA200301701B (en) * | 2000-09-15 | 2004-03-01 | Vertex Pharma | Pyrazole compounds useful as protein kinase inhibitors. |
| SI1318997T1 (sl) * | 2000-09-15 | 2006-12-31 | Vertex Pharma | Pirazolne spojine, uporabne kot inhibitorji protein-kinaze |
| US6660731B2 (en) | 2000-09-15 | 2003-12-09 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
| US7473691B2 (en) * | 2000-09-15 | 2009-01-06 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
| WO2002057259A2 (en) | 2000-12-21 | 2002-07-25 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
| KR100406634B1 (ko) * | 2001-03-12 | 2003-11-20 | 주식회사 엘지생명과학 | 3,5-디아미노인다졸 유도체, 그의 제조방법 및 사이클린의존성 키나아제 저해제로서의 그의 용도 |
| CA2460145C (en) | 2001-09-26 | 2011-04-26 | Pharmacia Italia S.P.A. | Aminoindazole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions containing them |
| EP1472245A2 (en) * | 2002-02-06 | 2004-11-03 | Vertex Pharmaceuticals Incorporated | Heteroaryl compounds useful as inhibitors of gsk-3 |
| FR2836915B1 (fr) * | 2002-03-11 | 2008-01-11 | Aventis Pharma Sa | Derives d'aminoindazoles, procede de preparation et intermediaires de ce procede a titre de medicaments et compositions pharmaceutiques les renfermant |
| DE60332604D1 (de) | 2002-03-15 | 2010-07-01 | Vertex Pharma | Azolylaminoazine als proteinkinasehemmer |
| AU2003227741A1 (en) | 2002-05-17 | 2003-12-02 | Pharmacia Italia S.P.A. | Aminoindazole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them |
| MY141867A (en) * | 2002-06-20 | 2010-07-16 | Vertex Pharma | Substituted pyrimidines useful as protein kinase inhibitors |
| DK1532145T3 (da) | 2002-08-02 | 2007-01-15 | Vertex Pharma | Pyrazolpræparater der er anvendelige som inhibitorer af GSK-3 |
| WO2004041285A1 (en) * | 2002-10-31 | 2004-05-21 | Amgen Inc. | Antiinflammation agents |
| US7601718B2 (en) | 2003-02-06 | 2009-10-13 | Vertex Pharmaceuticals Incorporated | Compositions useful as inhibitors of protein kinases |
| US7592340B2 (en) * | 2003-12-04 | 2009-09-22 | Vertex Pharmaceuticals Incorporated | Quinoxalines useful as inhibitors of protein kinases |
| DE102004005172A1 (de) * | 2004-02-02 | 2005-08-18 | Aventis Pharma Deutschland Gmbh | Indazolderivate als Inhibitoren der Hormon Sensitiven Lipase |
| WO2007022384A2 (en) | 2005-08-18 | 2007-02-22 | Vertex Pharmaceuticals Incorporated | Pyrazine kinase inhibitors |
| SG166828A1 (en) * | 2005-11-03 | 2010-12-29 | Vertex Pharma | Aminopyrimidines useful as kinase inhibitors |
| AU2007238019B2 (en) * | 2006-04-14 | 2013-03-14 | Abbvie Inc. | Process for the preparation of indazolyl ureas that inhibit vanilloid subtype 1 (VR1) receptors |
| MX2009004807A (es) | 2006-11-02 | 2009-06-15 | Vertex Pharma | Aminopiridinas y aminopirimidinas utiles como inhibidores de proteina cinasa. |
| CA2673353A1 (en) | 2006-12-19 | 2008-06-26 | Vertex Pharmaceuticals Incorporated | Aminopyrimidines useful as inhibitors of protein kinases |
| ATE526328T1 (de) | 2007-03-09 | 2011-10-15 | Vertex Pharma | Als inhibitoren von proteinkinasen geeignete aminopyrimidine |
| EP2134709A1 (en) | 2007-03-09 | 2009-12-23 | Vertex Pharmaceuticals, Inc. | Aminopyridines useful as inhibitors of protein kinases |
| MX2009009590A (es) | 2007-03-09 | 2009-11-10 | Vertex Pharma | Aminopirimidinas utiles como inhibidores de proteinas cinasas. |
| MX2009011059A (es) | 2007-04-13 | 2009-11-26 | Vertex Pharma | Aminopirimidinas utiles como inhibidores de cinasas. |
| JP5572087B2 (ja) * | 2007-05-02 | 2014-08-13 | バーテックス ファーマシューティカルズ インコーポレイテッド | キナーゼ阻害として有用なアミノピリミジン |
| CA2694381A1 (en) | 2007-05-02 | 2008-11-13 | Vertex Pharmaceuticals Incorporated | Aminopyrimidines useful as kinase inhibitors |
| CA2685876A1 (en) * | 2007-05-02 | 2008-11-13 | Vertex Pharmaceuticals Incorporated | Thiazoles and pyrazoles useful as kinase inhibitors |
| AU2008257044A1 (en) * | 2007-05-24 | 2008-12-04 | Vertex Pharmaceuticals Incorporated | Thiazoles and pyrazoles useful as kinase inhibitors |
| MX2010001137A (es) * | 2007-07-31 | 2010-03-31 | Vertex Pharma | Procesopara preparar 5-fluoro-1h-pirazol[3,4-b]piridin-3-amina y derivados del mismo. |
| RU2011112802A (ru) * | 2008-09-03 | 2012-10-10 | Вертекс Фармасьютикалз Инкорпорейтед (Us) | Сокристаллы и содержащие их фармацевтические композиции |
| DE102009004245A1 (de) | 2009-01-09 | 2010-07-15 | Bayer Schering Pharma Aktiengesellschaft | Neue anellierte, Heteroatom-verbrückte Pyrazol- und Imidazol-Derivate und ihre Verwendung |
| JP6317345B2 (ja) | 2012-07-24 | 2018-04-25 | ビアル−ポルテラ エ コンパニア，ソシエダッド アノニマ | ウレア化合物および酵素阻害剤としてのそれらの使用 |
| CA2880299A1 (en) * | 2012-07-27 | 2014-01-30 | Bial - Portela & Ca, S.A. | Process for the synthesis of substituted urea compounds |
| AU2014293731B2 (en) | 2013-07-24 | 2018-03-08 | Bial - Portela & Ca, S.A. | Imidazolecarboxamides and their use as FAAH inhibitors |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3133081A (en) * | 1964-05-12 | J-aminoindazole derivatives | ||
| CH397698A (de) * | 1961-09-08 | 1965-08-31 | Siegfried Ag | Verfahren zur Herstellung neuer 1-Carbamyl-indazole |
| US3274203A (en) * | 1963-05-31 | 1966-09-20 | Du Pont | 1-carbamyl and thiocarbamyl-3-amino-4-nonsubstituted and substituted pyrazoles |
| NL6707299A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1966-07-16 | 1968-01-17 | ||
| DE1770649A1 (de) * | 1968-06-15 | 1971-11-11 | Bayer Ag | Substituierte 3-Amino-indazole |
-
1974
- 1974-12-13 DE DE2458965A patent/DE2458965C3/de not_active Expired
-
1975
- 1975-10-28 GB GB44299/75A patent/GB1490306A/en not_active Expired
- 1975-11-24 US US05/634,914 patent/US4051252A/en not_active Expired - Lifetime
- 1975-11-27 CA CA240,662A patent/CA1059523A/en not_active Expired
- 1975-11-28 NO NO754024A patent/NO145382C/no unknown
- 1975-12-02 CS CS758165A patent/CS189731B2/cs unknown
- 1975-12-08 SU SU752195302A patent/SU604487A3/ru active
- 1975-12-09 CH CH1599575A patent/CH622250A5/de not_active IP Right Cessation
- 1975-12-10 IL IL48642A patent/IL48642A/xx unknown
- 1975-12-11 HU HU75BA3349A patent/HU173557B/hu unknown
- 1975-12-11 SE SE7513990A patent/SE419645B/xx unknown
- 1975-12-11 BE BE162651A patent/BE836528A/xx unknown
- 1975-12-11 DD DD190061A patent/DD125484A5/xx unknown
- 1975-12-11 JP JP50146940A patent/JPS5182266A/ja active Pending
- 1975-12-11 LU LU73993A patent/LU73993A1/xx unknown
- 1975-12-11 PL PL1975185475A patent/PL99858B1/pl unknown
- 1975-12-11 FI FI753493A patent/FI753493A7/fi not_active Application Discontinuation
- 1975-12-11 AT AT939775A patent/AT343653B/de not_active IP Right Cessation
- 1975-12-12 NL NL7514521A patent/NL7514521A/xx not_active Application Discontinuation
- 1975-12-12 IE IE2714/75A patent/IE42208B1/en unknown
- 1975-12-12 YU YU03152/75A patent/YU315275A/xx unknown
- 1975-12-12 FR FR7538124A patent/FR2293928A1/fr active Granted
- 1975-12-12 ZA ZA757777A patent/ZA757777B/xx unknown
- 1975-12-12 DK DK567275A patent/DK137082C/da active
- 1975-12-12 ES ES443429A patent/ES443429A1/es not_active Expired
-
1980
- 1980-08-29 KE KE3078A patent/KE3078A/xx unknown
- 1980-09-18 HK HK525/80A patent/HK52580A/xx unknown
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