CS189731B2 - Method of producing new derivatives of 3-aminoindazolcarboxylic acid - Google Patents

Method of producing new derivatives of 3-aminoindazolcarboxylic acid

Info

Publication number
CS189731B2
CS189731B2 CS758165A CS816575A CS189731B2 CS 189731 B2 CS189731 B2 CS 189731B2 CS 758165 A CS758165 A CS 758165A CS 816575 A CS816575 A CS 816575A CS 189731 B2 CS189731 B2 CS 189731B2
Authority
CS
Czechoslovakia
Prior art keywords
aminoindazolcarboxylic
acid
producing new
new derivatives
derivatives
Prior art date
Application number
CS758165A
Other languages
English (en)
Inventor
Karl H Mayer
Siegfried Petersen
Erich Klauke
Friedrich Hoffmeister
Wolfgang Wuttke
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of CS189731B2 publication Critical patent/CS189731B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CS758165A 1974-12-13 1975-12-02 Method of producing new derivatives of 3-aminoindazolcarboxylic acid CS189731B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2458965A DE2458965C3 (de) 1974-12-13 1974-12-13 3-Amino-indazol-N-carbonsäure-Derivate, Verfahren zu ihrer Herstellung sowie sie enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
CS189731B2 true CS189731B2 (en) 1979-04-30

Family

ID=5933305

Family Applications (1)

Application Number Title Priority Date Filing Date
CS758165A CS189731B2 (en) 1974-12-13 1975-12-02 Method of producing new derivatives of 3-aminoindazolcarboxylic acid

Country Status (27)

Country Link
US (1) US4051252A (cs)
JP (1) JPS5182266A (cs)
AT (1) AT343653B (cs)
BE (1) BE836528A (cs)
CA (1) CA1059523A (cs)
CH (1) CH622250A5 (cs)
CS (1) CS189731B2 (cs)
DD (1) DD125484A5 (cs)
DE (1) DE2458965C3 (cs)
DK (1) DK137082C (cs)
ES (1) ES443429A1 (cs)
FI (1) FI753493A7 (cs)
FR (1) FR2293928A1 (cs)
GB (1) GB1490306A (cs)
HK (1) HK52580A (cs)
HU (1) HU173557B (cs)
IE (1) IE42208B1 (cs)
IL (1) IL48642A (cs)
KE (1) KE3078A (cs)
LU (1) LU73993A1 (cs)
NL (1) NL7514521A (cs)
NO (1) NO145382C (cs)
PL (1) PL99858B1 (cs)
SE (1) SE419645B (cs)
SU (1) SU604487A3 (cs)
YU (1) YU315275A (cs)
ZA (1) ZA757777B (cs)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431657A (en) * 1982-05-24 1984-02-14 Ayerst, Mckenna & Harrison Inc. Analgesic compositions consisting of 2H-benzothieno[3,2-c]pyrazol-3-amine derivatives
KR20010086657A (ko) * 2000-03-02 2001-09-15 성재갑 아미노인다졸 유도체 및 이를 함유하는 싸이클린 의존키나아제 저해제 조성물
ATE346064T1 (de) 2000-09-15 2006-12-15 Vertex Pharma Pyrazolverbindungen als protein-kinasehemmer
US7473691B2 (en) * 2000-09-15 2009-01-06 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
US6660731B2 (en) 2000-09-15 2003-12-09 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
ZA200301701B (en) * 2000-09-15 2004-03-01 Vertex Pharma Pyrazole compounds useful as protein kinase inhibitors.
SI1318997T1 (sl) * 2000-09-15 2006-12-31 Vertex Pharma Pirazolne spojine, uporabne kot inhibitorji protein-kinaze
WO2002068415A1 (en) 2000-12-21 2002-09-06 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
KR100406634B1 (ko) * 2001-03-12 2003-11-20 주식회사 엘지생명과학 3,5-디아미노인다졸 유도체, 그의 제조방법 및 사이클린의존성 키나아제 저해제로서의 그의 용도
PL368347A1 (en) 2001-09-26 2005-03-21 Pharmacia Italia S.P.A. Aminoindazole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions containing them
RU2004126671A (ru) * 2002-02-06 2005-04-10 Вертекс Фармасьютикалз Инкорпорейтед (Us) Гетероарилсоединения, полезные в качестве ингибиторов gsk-3
FR2836915B1 (fr) * 2002-03-11 2008-01-11 Aventis Pharma Sa Derives d'aminoindazoles, procede de preparation et intermediaires de ce procede a titre de medicaments et compositions pharmaceutiques les renfermant
US20040009981A1 (en) 2002-03-15 2004-01-15 David Bebbington Compositions useful as inhibitors of protein kinases
WO2003097610A1 (en) 2002-05-17 2003-11-27 Pharmacia Italia S.P.A. Aminoindazole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
MY141867A (en) * 2002-06-20 2010-07-16 Vertex Pharma Substituted pyrimidines useful as protein kinase inhibitors
JP4733388B2 (ja) 2002-08-02 2011-07-27 バーテックス ファーマシューティカルズ インコーポレイテッド Ｇｓｋ−３のインヒビターとして有用なピラゾール組成物
CA2502429A1 (en) * 2002-10-31 2004-05-21 Amgen Inc. Antiinflammation agents
US7601718B2 (en) 2003-02-06 2009-10-13 Vertex Pharmaceuticals Incorporated Compositions useful as inhibitors of protein kinases
JP2007513184A (ja) * 2003-12-04 2007-05-24 バーテックス　ファーマシューティカルズ　インコーポレイテッド プロテインキナーゼのインヒビターとして有用なキノキサリン
DE102004005172A1 (de) 2004-02-02 2005-08-18 Aventis Pharma Deutschland Gmbh Indazolderivate als Inhibitoren der Hormon Sensitiven Lipase
EP1917259B1 (en) 2005-08-18 2012-01-25 Vertex Pharmaceuticals Incorporated Pyrazine kinase inhibitors
WO2007056163A2 (en) 2005-11-03 2007-05-18 Vertex Pharmaceuticals Incorporated Aminopyrimidines useful as kinase inhibitors
US7847104B2 (en) * 2006-04-14 2010-12-07 Abbott Laboratories Process for the preparation of indazolyl ureas that inhibit Vanilloid subtype1 (VR1) receptors
NZ576750A (en) 2006-11-02 2012-01-12 Vertex Pharma Aminopyridines and aminopyrimidines useful as inhibitors of protein kinases
AU2007333650A1 (en) 2006-12-19 2008-06-26 Vertex Pharmaceuticals Incorporated Aminopyrimidines useful as inhibitors of protein kinases
MX2009009592A (es) 2007-03-09 2009-11-10 Vertex Pharma Aminopiridinas utiles como inhibidores de proteinas cinasas.
WO2008112651A2 (en) 2007-03-09 2008-09-18 Vertex Pharmaceuticals Incorporated Aminopyrimidines useful as inhibitors of protein kinases
WO2008112642A1 (en) 2007-03-09 2008-09-18 Vertex Pharmaceuticals Incorporated Aminopyrimidines useful as inhibitors of protein kinases
AU2008240313A1 (en) 2007-04-13 2008-10-23 Aj Park Aminopyrimidines useful as kinase inhibitors
WO2008137622A2 (en) * 2007-05-02 2008-11-13 Vertex Pharmaceuticals Incorporated Aminopyrimidines useful as kinase inhibitors
CN101801959A (zh) 2007-05-02 2010-08-11 沃泰克斯药物股份有限公司 可用作激酶抑制剂的氨基嘧啶类化合物
CN101679378A (zh) * 2007-05-02 2010-03-24 沃泰克斯药物股份有限公司 用作激酶抑制剂的噻唑和吡唑
CN101687852A (zh) * 2007-05-24 2010-03-31 沃泰克斯药物股份有限公司 可用作激酶抑制剂的噻唑类和吡唑类化合物
JP5553751B2 (ja) 2007-07-31 2014-07-16 バーテックス ファーマシューティカルズ インコーポレイテッド ５−フルオロ−１Ｈ−ピラゾロ［３，４−ｂ］ピリジン−３−アミンおよびその誘導体を調製するためのプロセス
WO2010027921A1 (en) * 2008-09-03 2010-03-11 Vertex Pharmaceuticals Incorporated Co-crystals and pharmaceutical formulations comprising the same
DE102009004245A1 (de) 2009-01-09 2010-07-15 Bayer Schering Pharma Aktiengesellschaft Neue anellierte, Heteroatom-verbrückte Pyrazol- und Imidazol-Derivate und ihre Verwendung
HRP20180543T1 (hr) 2012-07-24 2018-06-29 Bial-Portela & Ca, S.A. Spojevi uree i njihova upotreba kao inhibitora enzima
JP2015528013A (ja) * 2012-07-27 2015-09-24 ビアル−ポルテラ エ コンパニア，ソシエダッド アノニマ 置換ウレア化合物の合成方法
CA2918993C (en) 2013-07-24 2021-08-24 Bial - Portela & Ca, S.A. Imidazolecarboxamides and their use as faah inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3133081A (en) * 1964-05-12 J-aminoindazole derivatives
CH397698A (de) * 1961-09-08 1965-08-31 Siegfried Ag Verfahren zur Herstellung neuer 1-Carbamyl-indazole
US3277100A (en) * 1963-05-31 1966-10-04 Du Pont Novel substituted pyrazoles
NL6707299A (cs) * 1966-07-16 1968-01-17
DE1770649A1 (de) * 1968-06-15 1971-11-11 Bayer Ag Substituierte 3-Amino-indazole

Also Published As

Publication number Publication date
FI753493A7 (cs) 1976-06-14
AT343653B (de) 1978-06-12
SE419645B (sv) 1981-08-17
US4051252A (en) 1977-09-27
BE836528A (fr) 1976-06-11
SE7513990L (sv) 1976-06-14
PL99858B1 (pl) 1978-08-31
ES443429A1 (es) 1977-04-16
FR2293928B1 (cs) 1979-09-21
DK137082B (da) 1978-01-16
CH622250A5 (cs) 1981-03-31
NO145382B (no) 1981-11-30
NO145382C (no) 1982-03-10
IL48642A0 (en) 1976-02-29
IL48642A (en) 1979-12-30
YU315275A (en) 1982-02-28
DD125484A5 (cs) 1977-04-20
DE2458965B2 (de) 1979-02-22
ZA757777B (en) 1976-11-24
DK137082C (da) 1978-06-19
DE2458965C3 (de) 1979-10-11
LU73993A1 (cs) 1976-11-11
JPS5182266A (en) 1976-07-19
DK567275A (da) 1976-06-14
SU604487A3 (ru) 1978-04-25
IE42208B1 (en) 1980-06-18
HU173557B (hu) 1979-06-28
DE2458965A1 (de) 1976-06-16
HK52580A (en) 1980-09-26
CA1059523A (en) 1979-07-31
NO754024L (cs) 1976-06-15
AU8717075A (en) 1977-06-09
IE42208L (en) 1976-06-13
ATA939775A (de) 1977-10-15
KE3078A (en) 1980-10-03
NL7514521A (nl) 1976-06-15
GB1490306A (en) 1977-11-02
FR2293928A1 (fr) 1976-07-09

Similar Documents

Publication Publication Date Title
CS189731B2 (en) Method of producing new derivatives of 3-aminoindazolcarboxylic acid
JPS53101385A (en) Method of producing phenyllpyrimidine
CS188985B2 (en) Method of producing aryl-1-azolylmethanes
CS190478B2 (en) Method of producing novel biphenylyl derivatives
CS194749B2 (en) Method of producing novel derivatives of 3-sulphonyl-ox!-crotonic acid
CS189709B2 (en) Method of producing 6-d-/-/-alpha-amino-alpha-/p-acetoxyphenylacetamido/penicillanic acid
CS188235B2 (en) Method of producing new derivatives ryfamicine
CS191264B2 (en) Method of producing new pyridobenzodiazepinones
CS183850B2 (en) Method of producing 5-fluor-2-methyl-1-/p-methyl-sulphinylbenzyliden/-3-indenylacetic acid
CS188938B2 (en) Method of producing xanthene-9-spiro-4-piperidines
SU677666A3 (en) Method of producing 7l-or extradiols
YU118575A (en) Process for obtaining new derivatives of 13-thiaprostanoic acid
CS190489B2 (en) Method of producing novel derivatives of prostanoic acid
HU170859B (hu) Sposob poluchenija novykh proizvodnykh 6-skobka-al'fa-ureido-fenilacetilamido-skobka zakryta-penam-3-karbonovojj kisloty
CS189635B2 (en) Method of producing bromderivatives of 4-imido-thioazetidin-2-one
CS192518B2 (en) Method of producing derivatives of 3-cinnolincarboxylic acid
CS182298B2 (en) Method of producing substituted benzendisulphon-amides
CS187333B2 (en) Method of producing derivatives of prostanoic acid
HU171053B (hu) Sposob poluchenija novykh proizvodnykh 7-skobka-2-ureido-acetamido-skobka zakryta-3-geterociklicheskijj-tiometil-cef-3-em-4-karbonovojj kisloty
CS189753B2 (en) Method of producing derivatives of prostanic acid
HU175345B (hu) Sposob poluchenija novykh proizvodnykh 15-gidroksi-16s- i -16r-alkil-prost-5-en-13-in-karbonovykh kislot
CS188945B2 (en) Method of producing 1-aryluracils
CS185675B2 (en) Method of producing 7-amino-delta up3-cephem derivatives
CS181278B2 (en) Method of producing cephalosporane acid derivatives
BG25086A3 (en) A method of obtaining derivatives of thiazolidinon-acetic acid