JPS5515455A - 2-substituted-methyl-1,4-benzodioxane - Google Patents

2-substituted-methyl-1,4-benzodioxane

Info

Publication number
JPS5515455A
JPS5515455A JP8911978A JP8911978A JPS5515455A JP S5515455 A JPS5515455 A JP S5515455A JP 8911978 A JP8911978 A JP 8911978A JP 8911978 A JP8911978 A JP 8911978A JP S5515455 A JPS5515455 A JP S5515455A
Authority
JP
Japan
Prior art keywords
methyl
benzodioxane
substituted
formula
oxo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8911978A
Other languages
Japanese (ja)
Inventor
Toshihiro Yamada
Azuma Yamaguchi
Hiroshi Shimamura
Masahiro Takatani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MORISHITA SEIYAKU KK
Morishita Pharmaceuticals Co Ltd
Original Assignee
MORISHITA SEIYAKU KK
Morishita Pharmaceuticals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MORISHITA SEIYAKU KK, Morishita Pharmaceuticals Co Ltd filed Critical MORISHITA SEIYAKU KK
Priority to JP8911978A priority Critical patent/JPS5515455A/en
Publication of JPS5515455A publication Critical patent/JPS5515455A/en
Pending legal-status Critical Current

Links

Landscapes

  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:2-Substituted-methyl-1,4-benzodioxane of formula I [R is 3-oxo- 4,5-dihydro-6-R1-2-pyridazinyl, N-R2-N-methylamino; R1 is methyl, carboxy, phenyl, p-methoxy-phenyl, etc.; R2 is β-(2-oxo-1-benzoxazolyl)ethyl, β-(2-oxo-1- benzothiazolyl)ethyl, etc.].
EXAMPLE: 2-( 1, 4-Benzodioxan-2-ly )methyl-4, 5-dihydro-6-methyl-3( 2H )-pyridazinone.
USE: Mild and long-acting hypotensive agent.
PROCESS: Reaction of 2-hydrazino or 2-substituted aminomethyl-1,4-benzodioxane of formula II (R3 is hydrazino, etc.) with γ-ketoacid of formula III or 2-benzoxazolone (R4) affords the compound of formula I.
COPYRIGHT: (C)1980,JPO&Japio
JP8911978A 1978-07-19 1978-07-19 2-substituted-methyl-1,4-benzodioxane Pending JPS5515455A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP8911978A JPS5515455A (en) 1978-07-19 1978-07-19 2-substituted-methyl-1,4-benzodioxane

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8911978A JPS5515455A (en) 1978-07-19 1978-07-19 2-substituted-methyl-1,4-benzodioxane

Publications (1)

Publication Number Publication Date
JPS5515455A true JPS5515455A (en) 1980-02-02

Family

ID=13961993

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8911978A Pending JPS5515455A (en) 1978-07-19 1978-07-19 2-substituted-methyl-1,4-benzodioxane

Country Status (1)

Country Link
JP (1) JPS5515455A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999023083A1 (en) * 1997-11-05 1999-05-14 Mitsubishi Chemical Corporation Novel alkylamino derivatives
US6528679B1 (en) 1999-09-29 2003-03-04 Tosoh Corporation Process for producing phenyl esters using palladium-based catalysts

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999023083A1 (en) * 1997-11-05 1999-05-14 Mitsubishi Chemical Corporation Novel alkylamino derivatives
US6528679B1 (en) 1999-09-29 2003-03-04 Tosoh Corporation Process for producing phenyl esters using palladium-based catalysts
US6958407B2 (en) 1999-09-29 2005-10-25 Tosoh Corporation Process for producing phenyl ester, and catalyst

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