GB0724342D0 - Anitbacterial compositions - Google Patents
Anitbacterial compositionsInfo
- Publication number
- GB0724342D0 GB0724342D0 GBGB0724342.1A GB0724342A GB0724342D0 GB 0724342 D0 GB0724342 D0 GB 0724342D0 GB 0724342 A GB0724342 A GB 0724342A GB 0724342 D0 GB0724342 D0 GB 0724342D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- anitbacterial
- compositions
- anitbacterial compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 230000000844 anti-bacterial effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (14)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0724342.1A GB0724342D0 (en) | 2007-12-13 | 2007-12-13 | Anitbacterial compositions |
| CN200880126437.2A CN102015700B (zh) | 2007-12-13 | 2008-12-12 | 抗菌稠合噻唑 |
| CA 2709021 CA2709021A1 (en) | 2007-12-13 | 2008-12-12 | Antibacterial condensed thiazoles |
| PCT/GB2008/004114 WO2009074812A1 (en) | 2007-12-13 | 2008-12-12 | Antibacterial condensed thiazoles |
| EP20080859786 EP2231653B1 (en) | 2007-12-13 | 2008-12-12 | Antibacterial condensed thiazoles |
| AU2008334427A AU2008334427B2 (en) | 2007-12-13 | 2008-12-12 | Antibacterial condensed thiazoles |
| KR20107015443A KR20100105847A (ko) | 2007-12-13 | 2008-12-12 | 항균성 농축 티아졸 |
| NZ586508A NZ586508A (en) | 2007-12-13 | 2008-12-12 | Antibacterial condensed thiazoles |
| US12/747,811 US8299065B2 (en) | 2007-12-13 | 2008-12-12 | Antibacterial condensed thiazoles |
| MX2010006428A MX2010006428A (es) | 2007-12-13 | 2008-12-12 | Tiazoles condensados antibacterianos. |
| ES08859786T ES2416059T3 (es) | 2007-12-13 | 2008-12-12 | Tiazoles condensados antibacterianos |
| JP2010537517A JP5539898B2 (ja) | 2007-12-13 | 2008-12-12 | 抗菌活性縮合チアゾール |
| EA201000993A EA018104B1 (ru) | 2007-12-13 | 2008-12-12 | Конденсированные тиазолы, обладающие антибактериальными свойствами |
| BRPI0820656-2A BRPI0820656A2 (pt) | 2007-12-13 | 2008-12-12 | Tiazóis condensados antibacterianos |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0724342.1A GB0724342D0 (en) | 2007-12-13 | 2007-12-13 | Anitbacterial compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB0724342D0 true GB0724342D0 (en) | 2008-01-30 |
Family
ID=39048076
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB0724342.1A Ceased GB0724342D0 (en) | 2007-12-13 | 2007-12-13 | Anitbacterial compositions |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8299065B2 (enExample) |
| EP (1) | EP2231653B1 (enExample) |
| JP (1) | JP5539898B2 (enExample) |
| KR (1) | KR20100105847A (enExample) |
| CN (1) | CN102015700B (enExample) |
| AU (1) | AU2008334427B2 (enExample) |
| BR (1) | BRPI0820656A2 (enExample) |
| CA (1) | CA2709021A1 (enExample) |
| EA (1) | EA018104B1 (enExample) |
| ES (1) | ES2416059T3 (enExample) |
| GB (1) | GB0724342D0 (enExample) |
| MX (1) | MX2010006428A (enExample) |
| NZ (1) | NZ586508A (enExample) |
| WO (1) | WO2009074812A1 (enExample) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20110031419A (ko) * | 2008-06-04 | 2011-03-28 | 아스트라제네카 아베 | 항박테리아제로서의 티아졸로［５,４ｂ］피리딘 및 옥사졸로［５,４ｂ］피리딘 유도체 |
| US20110166088A1 (en) * | 2008-06-25 | 2011-07-07 | Ranbaxy Laboratories Limited | Benzothiazoles and aza-analogues thereof use as antibacterial agents |
| CN102725274A (zh) | 2009-10-16 | 2012-10-10 | Rib-X制药公司 | 抗微生物化合物和其制备和使用方法 |
| KR20190044136A (ko) * | 2009-10-16 | 2019-04-29 | 멜린타 서브시디어리 코프. | 항미생물성 화합물 및 이의 제조 방법 및 사용 방법 |
| NZ599289A (en) | 2009-10-16 | 2014-11-28 | Melinta Therapeutics Inc | Antimicrobial compounds and methods of making and using the same |
| WO2011121555A1 (en) | 2010-03-31 | 2011-10-06 | Actelion Pharmaceuticals Ltd | Antibacterial isoquinolin-3-ylurea derivatives |
| WO2011149822A1 (en) | 2010-05-26 | 2011-12-01 | Boehringer Ingelheim International Gmbh | 2-oxo-1,2-dihydropyridin-4-ylboronic acid derivatives |
| EP2625178A4 (en) * | 2010-10-08 | 2014-04-30 | Biota Europe Ltd | BACTERIA TOPOISOMERASE II FOR INHIBITING 2-ETHYL CARBAMOYLAMINE-1,3-BENZOTHIAZOL-5-YLENE |
| SG191946A1 (en) | 2011-01-14 | 2013-08-30 | Vertex Pharma | Pyrimidine gyrase and topoisomerase iv inhibitors |
| WO2012097273A1 (en) | 2011-01-14 | 2012-07-19 | Vertex Pharmaceuticals Incorporated | Solid forms of gyrase inhibitor (r)-1-ethyl-3-[6-fluoro-5-[2-(1-hydroxy-1-methyl-ethyl) pyrimidin-5-yl]-7-(tetrahydrofuran-2-yl)-1h-benzimidazol-2-yl]urea |
| AU2012205420B2 (en) | 2011-01-14 | 2016-12-08 | Spero Therapeutics, Inc. | Process of making gyrase and topoisomerase IV inhibitors |
| RU2013137753A (ru) | 2011-01-14 | 2015-02-20 | Вертекс Фармасьютикалз Инкорпорейтед | Твердые формы ингибитора гиразы (r)-1-этил-3-[5-[2-(1-гидрокси-1-метилэтил)пиримидин-5-ил]-7-(тетрагидрофуран-2-ил)-1н-бензимидазол-2-ил]мочевины |
| CA2828824A1 (en) * | 2011-03-28 | 2012-10-04 | F. Hoffmann-La Roche Ag | Thiazolopyrimidine compounds |
| AR088729A1 (es) | 2011-03-29 | 2014-07-02 | Actelion Pharmaceuticals Ltd | Derivados de 3-ureidoisoquinolin-8-ilo y una composicion farmaceutica |
| EA201391536A1 (ru) | 2011-04-15 | 2014-08-29 | Мелинта Терапьютикс, Инк. | Противомикробные соединения и способы их получения и применения |
| CN103702994B (zh) | 2011-06-20 | 2016-03-23 | 沃泰克斯药物股份有限公司 | 旋转酶和拓扑异构酶抑制剂的磷酸酯 |
| US9822108B2 (en) | 2012-01-13 | 2017-11-21 | Rutgers, The State University Of New Jersey | Antimicrobial agents |
| AU2013235038A1 (en) | 2012-03-21 | 2014-10-09 | Malvika Kaul | Antimicrobial agents |
| CN104302645A (zh) * | 2012-03-22 | 2015-01-21 | 生物区欧洲有限公司 | 抗菌化合物 |
| CN104603136B (zh) * | 2012-07-10 | 2017-06-27 | 拜耳医药股份有限公司 | 制备取代的三唑并吡啶的方法 |
| US9018216B2 (en) | 2012-07-18 | 2015-04-28 | Vertex Pharmaceuticals Incorporated | Solid forms of (R)-2-(5-(2-(3-ethylureido)-6-fluoro-7-(tetrahydrofuran-2-yl)-1H-benzo[d]imidazol-5-yl)pyrimidin-2-yl)propan-2-yl dihydrogen phosphate and salts thereof |
| US9572809B2 (en) | 2012-07-18 | 2017-02-21 | Spero Trinem, Inc. | Combination therapy to treat Mycobacterium diseases |
| KR102057877B1 (ko) | 2012-07-18 | 2019-12-20 | 노스 앤드 사우스 브라더 파마시 인베스트먼트 컴파니 리미티드 | 질소함유 헤테로고리 유도체 및 그의 약물에서의 용도 |
| UA117672C2 (uk) | 2012-12-21 | 2018-09-10 | ЯНССЕН САЙЄНСІЗ АЙРЛЕНД ЮСі | Антибактеріальні сполуки |
| EP3038623A4 (en) | 2013-09-09 | 2017-04-19 | Melinta Therapeutics, Inc. | Antimicrobial compounds and methods of making and using the same |
| SG10201801956SA (en) | 2013-09-09 | 2018-04-27 | Melinta Therapeutics Inc | Antimicrobial compounds and methods of making and using the same |
| US9458150B2 (en) | 2013-11-08 | 2016-10-04 | Rutgers, The State University Of New Jersey | Antimicrobial agents |
| SG11201606332PA (en) | 2014-02-03 | 2016-09-29 | Spero Gyrase Inc | Antibacterial combinations comprising polymyxin |
| CN105367547B (zh) * | 2014-08-19 | 2019-04-23 | 北京桦冠生物技术有限公司 | 一种噁唑啉酮抗生素的新合成工艺 |
| AR102215A1 (es) * | 2014-10-10 | 2017-02-15 | Glaxosmithkline Ip Dev Ltd | Compuesto de pirazol-4-carboxamida, composición farmacéutica que lo comprende y su uso para la fabricación de un medicamento |
| JP2018507881A (ja) | 2015-03-11 | 2018-03-22 | メリンタ セラピューティクス，インコーポレイテッド | 抗微生物化合物ならびにこれらを作製および使用する方法 |
| US10513528B2 (en) | 2016-02-25 | 2019-12-24 | Taxis Pharmaceuticals, Inc. | Synthetic processes and intermediates |
| CN109069492B (zh) | 2016-04-08 | 2021-12-10 | 快尔生物技术公司 | 环稠和的噻唑啉2-吡啶酮、其制备方法及其在治疗和/或预防结核中的用途 |
| CA3023317A1 (en) | 2016-05-06 | 2017-11-09 | Melinta Therapeutics, Inc. | Antimicrobials and methods of making and using same |
| WO2018174288A1 (ja) | 2017-03-24 | 2018-09-27 | 大正製薬株式会社 | ２（１ｈ）－キノリノン誘導体 |
| US10774093B2 (en) | 2017-03-30 | 2020-09-15 | Taxis Pharmaceuticals, Inc. | Synthetic processes and synthetic intermediates |
| CN107325093B (zh) * | 2017-07-09 | 2020-06-05 | 西南科技大学 | 具抗菌活性的硫脲类化合物合成及应用 |
| AU2019223215B2 (en) | 2018-02-23 | 2022-09-15 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Novel inhibitors of bacterial glutaminyl cyclases for use in the treatment of periodontal and related diseases |
| BR112022004451A2 (pt) | 2019-09-13 | 2022-06-21 | Nimbus Saturn Inc | Antagonistas de hpk1 e usos dos mesmos |
| CN117120090A (zh) | 2021-02-12 | 2023-11-24 | 林伯士萨顿公司 | Hpk1拮抗剂和其用途 |
| JP2024509192A (ja) | 2021-03-05 | 2024-02-29 | ニンバス サターン， インコーポレイテッド | Ｈｐｋ１アンタゴニスト及びその使用 |
| JP2024513011A (ja) | 2021-03-29 | 2024-03-21 | ニンバス サターン， インコーポレイテッド | Ｈｐｋ１アンタゴニスト及びその使用 |
| WO2025202955A1 (en) | 2024-03-28 | 2025-10-02 | Pi Industries Ltd. | Fused bicyclic compounds and their use as pest control agents |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH505543A (de) | 1968-11-01 | 1971-04-15 | Ciba Geigy Ag | Schädlingsbekämpfungsmittel |
| US4028374A (en) | 1975-11-03 | 1977-06-07 | Morton-Norwich Products, Inc. | Antibacterial thiocyanatobenzothiazoles |
| JPS57149280A (en) * | 1981-03-10 | 1982-09-14 | Kyowa Hakko Kogyo Co Ltd | Amino acid derivative and its preparation |
| SK12712002A3 (sk) | 2000-02-07 | 2003-02-04 | Abbott Gmbh & Co. Kg | Deriváty 2-benzotiazolylmočoviny a ich použitie ako inhibítorov proteínkináz |
| CA2413086C (en) | 2000-06-21 | 2011-06-28 | Alexander Alanine | Benzothiazole derivatives |
| IL156031A0 (en) * | 2000-12-15 | 2003-12-23 | Vertex Pharma | Fused heterocyclic derivatives and pharmaceutical compositions containing the same |
| CA2489128C (en) | 2002-06-13 | 2012-01-03 | Vertex Pharmaceuticals Incorporated | 2-ureido-6-heteroaryl-3h-benzoimidazole-4-carboxylic acid derivatives and related compounds as gyrase and/or topoisomerase iv inhibitors for the treatment of bacterial infections |
| AR042956A1 (es) | 2003-01-31 | 2005-07-13 | Vertex Pharma | Inhibidores de girasa y usos de los mismos |
| EP1680431A1 (en) | 2003-10-17 | 2006-07-19 | Rigel Pharmaceuticals, Inc. | Benzothiazole and thiazole'5,5-b!pyridine compositions and their use as ubiquitin ligase inhibitors |
| TW200621723A (en) * | 2004-09-09 | 2006-07-01 | Chugai Pharmaceutical Co Ltd | Novel imidazolidine derivative and use thereof |
| GB0612428D0 (en) | 2006-06-22 | 2006-08-02 | Prolysis Ltd | Antibacterial agents |
-
2007
- 2007-12-13 GB GBGB0724342.1A patent/GB0724342D0/en not_active Ceased
-
2008
- 2008-12-12 NZ NZ586508A patent/NZ586508A/en not_active IP Right Cessation
- 2008-12-12 EP EP20080859786 patent/EP2231653B1/en not_active Not-in-force
- 2008-12-12 EA EA201000993A patent/EA018104B1/ru not_active IP Right Cessation
- 2008-12-12 BR BRPI0820656-2A patent/BRPI0820656A2/pt not_active IP Right Cessation
- 2008-12-12 CN CN200880126437.2A patent/CN102015700B/zh not_active Expired - Fee Related
- 2008-12-12 WO PCT/GB2008/004114 patent/WO2009074812A1/en not_active Ceased
- 2008-12-12 KR KR20107015443A patent/KR20100105847A/ko not_active Ceased
- 2008-12-12 ES ES08859786T patent/ES2416059T3/es active Active
- 2008-12-12 MX MX2010006428A patent/MX2010006428A/es active IP Right Grant
- 2008-12-12 US US12/747,811 patent/US8299065B2/en not_active Expired - Fee Related
- 2008-12-12 JP JP2010537517A patent/JP5539898B2/ja not_active Expired - Fee Related
- 2008-12-12 CA CA 2709021 patent/CA2709021A1/en not_active Abandoned
- 2008-12-12 AU AU2008334427A patent/AU2008334427B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US8299065B2 (en) | 2012-10-30 |
| EA201000993A1 (ru) | 2011-02-28 |
| KR20100105847A (ko) | 2010-09-30 |
| US20100305067A1 (en) | 2010-12-02 |
| NZ586508A (en) | 2012-05-25 |
| AU2008334427B2 (en) | 2014-06-19 |
| CA2709021A1 (en) | 2009-06-18 |
| CN102015700A (zh) | 2011-04-13 |
| EP2231653B1 (en) | 2013-04-03 |
| JP2011506417A (ja) | 2011-03-03 |
| EP2231653A1 (en) | 2010-09-29 |
| JP5539898B2 (ja) | 2014-07-02 |
| AU2008334427A1 (en) | 2009-06-18 |
| WO2009074812A1 (en) | 2009-06-18 |
| CN102015700B (zh) | 2014-12-03 |
| ES2416059T3 (es) | 2013-07-30 |
| MX2010006428A (es) | 2010-09-30 |
| EA018104B1 (ru) | 2013-05-30 |
| BRPI0820656A2 (pt) | 2015-06-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AT | Applications terminated before publication under section 16(1) |