BRPI0820656A2 - Tiazóis condensados antibacterianos - Google Patents
Tiazóis condensados antibacterianosInfo
- Publication number
- BRPI0820656A2 BRPI0820656A2 BRPI0820656-2A BRPI0820656A BRPI0820656A2 BR PI0820656 A2 BRPI0820656 A2 BR PI0820656A2 BR PI0820656 A BRPI0820656 A BR PI0820656A BR PI0820656 A2 BRPI0820656 A2 BR PI0820656A2
- Authority
- BR
- Brazil
- Prior art keywords
- antibacterial
- thiazoles
- condensed thiazoles
- antibacterial condensed
- condensed
- Prior art date
Links
- 230000000844 anti-bacterial Effects 0.000 title 1
- 150000003557 thiazoles Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring-systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0724342.1A GB0724342D0 (en) | 2007-12-13 | 2007-12-13 | Anitbacterial compositions |
| PCT/GB2008/004114 WO2009074812A1 (en) | 2007-12-13 | 2008-12-12 | Antibacterial condensed thiazoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0820656A2 true BRPI0820656A2 (pt) | 2015-06-16 |
Family
ID=39048076
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0820656-2A BRPI0820656A2 (pt) | 2007-12-13 | 2008-12-12 | Tiazóis condensados antibacterianos |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8299065B2 (pt) |
| EP (1) | EP2231653B1 (pt) |
| JP (1) | JP5539898B2 (pt) |
| KR (1) | KR20100105847A (pt) |
| CN (1) | CN102015700B (pt) |
| AU (1) | AU2008334427B2 (pt) |
| BR (1) | BRPI0820656A2 (pt) |
| CA (1) | CA2709021A1 (pt) |
| EA (1) | EA018104B1 (pt) |
| ES (1) | ES2416059T3 (pt) |
| GB (1) | GB0724342D0 (pt) |
| MX (1) | MX2010006428A (pt) |
| NZ (1) | NZ586508A (pt) |
| WO (1) | WO2009074812A1 (pt) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009147431A1 (en) * | 2008-06-04 | 2009-12-10 | Astrazeneca Ab | Thiazolo [5, 4-b] pyridine and oxazolo [5, 4-b] pyridine derivatives as antibacterial agents |
| EP2321309A1 (en) * | 2008-06-25 | 2011-05-18 | Ranbaxy Laboratories Limited | Benzothiazoles and aza-analogues thereof use as antibacterial agents |
| CN102712657A (zh) | 2009-10-16 | 2012-10-03 | Rib-X制药公司 | 抗微生物化合物和其制备和使用方法 |
| CN102712647B (zh) * | 2009-10-16 | 2018-04-24 | 梅琳塔治疗公司 | 抗微生物化合物和其制备和使用方法 |
| JP2013508299A (ja) | 2009-10-16 | 2013-03-07 | リブ−エックス ファーマシューティカルズ，インコーポレイテッドＲｉｂ−Ｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | Antimicrobial compounds and methods of making and using antimicrobial compounds |
| BR112012024705A2 (pt) | 2010-03-31 | 2016-06-07 | Actelion Pharmaceuticals Ltd | derivados antibacterianos de isoquinolin-3-ilureia |
| JP2013531636A (ja) | 2010-05-26 | 2013-08-08 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ２−オキソ−１，２−ジヒドロピリジン−４−イルボロン酸誘導体 |
| JP5864589B2 (ja) * | 2010-10-08 | 2016-02-17 | ビオタ ヨーロッパ リミテッドＢｉｏｔａ Ｅｕｒｏｐｅ Ｌｔｄ | 細菌トポイソメラーゼｉｉ阻害性２−エチルカルバモイルアミノ−１，３−ベンゾチアゾール−５−イル類 |
| EP2663557B1 (en) | 2011-01-14 | 2015-05-27 | Vertex Pharmaceuticals Incorporated | Pyrimidine gyrase and topoisomerase iv inhibitors |
| CA2824403C (en) | 2011-01-14 | 2019-09-24 | Vertex Pharmaceuticals Incorporated | Solid forms of gyrase inhibitor (r)-1-ethyl-3-[6-fluoro-5-[2-(1-hydroxy-1-methyl-ethyl)pyrimidin-5-yl]-7-(tetrahydrofuran-2-yl)-1h-benzimidazol-2-yl]urea |
| CN103384666A (zh) | 2011-01-14 | 2013-11-06 | 沃泰克斯药物股份有限公司 | 固体形式的促旋酶抑制剂（r）-1-乙基-3-[5-[2-（1-羟基-1-甲基-乙基）嘧啶-5-基]-7-（四氢呋喃-2-基）-1氢-苯并咪唑-2-基]脲 |
| TWI534143B (zh) | 2011-01-14 | 2016-05-21 | 維泰克斯製藥公司 | 製造旋轉酶及拓樸異構酶ｉｖ抑制劑之方法 |
| ES2588680T3 (es) * | 2011-03-28 | 2016-11-04 | F. Hoffmann-La Roche Ag | Compuestos de tiazolopirimidina |
| AR088729A1 (es) | 2011-03-29 | 2014-07-02 | Actelion Pharmaceuticals Ltd | Derivados de 3-ureidoisoquinolin-8-ilo y una composicion farmaceutica |
| JP6317669B2 (ja) | 2011-04-15 | 2018-04-25 | メリンタ セラピューティクス インコーポレイテッド | 抗菌化合物ならびにそれを作製および使用する方法 |
| US9125922B2 (en) | 2011-06-20 | 2015-09-08 | Vertex Pharmaceuticals Incorporated | Phosphate esters of gyrase and topoisomerase inhibitors |
| WO2013106756A2 (en) | 2012-01-13 | 2013-07-18 | Rutgers, The State University Of New Jersey | Antimicrobial agents |
| CA2868002A1 (en) | 2012-03-21 | 2013-09-26 | Rutgers, The State University Of New Jersey | Antimicrobial agents |
| US8906902B2 (en) | 2012-03-22 | 2014-12-09 | Biota Europe Limited | Antibacterial compounds |
| MX2015000348A (es) * | 2012-07-10 | 2015-04-14 | Bayer Pharma AG | METHODS TO PREPARE SUBSTITUTED TRIAZOLOPIRIDINS. |
| US9572809B2 (en) | 2012-07-18 | 2017-02-21 | Spero Trinem, Inc. | Combination therapy to treat Mycobacterium diseases |
| KR102057877B1 (ko) * | 2012-07-18 | 2019-12-20 | 노스 앤드 사우스 브라더 파마시 인베스트먼트 컴파니 리미티드 | 질소함유 헤테로고리 유도체 및 그의 약물에서의 용도 |
| US9018216B2 (en) | 2012-07-18 | 2015-04-28 | Vertex Pharmaceuticals Incorporated | Solid forms of (R)-2-(5-(2-(3-ethylureido)-6-fluoro-7-(tetrahydrofuran-2-yl)-1H-benzo[d]imidazol-5-yl)pyrimidin-2-yl)propan-2-yl dihydrogen phosphate and salts thereof |
| AP201508503A0 (en) | 2012-12-21 | 2015-06-30 | Janssen Sciences Ireland Uc | Antibacterial compounds |
| WO2015035421A1 (en) | 2013-09-09 | 2015-03-12 | Melinta Therapeutics, Inc. | Antimicrobial compounds and methods of making and using the same |
| US10106543B2 (en) | 2013-09-09 | 2018-10-23 | Melinta Therapeutics, Inc. | Antimicrobial compounds and methods of making and using the same |
| US9458150B2 (en) | 2013-11-08 | 2016-10-04 | Rutgers, The State University Of New Jersey | Antimicrobial agents |
| US20170007615A1 (en) | 2014-02-03 | 2017-01-12 | Biota Europe Ltd | Antibacterial Compounds |
| CN105367547B (zh) * | 2014-08-19 | 2019-04-23 | 北京桦冠生物技术有限公司 | 一种噁唑啉酮抗生素的新合成工艺 |
| UY36350A (es) * | 2014-10-10 | 2016-06-01 | Glaxosmithkline Ip Dev Ltd | Compuesto derivado de pirazol para tratamiento o prevención de la enfermedad de chagas. |
| EP3419967A4 (en) | 2016-02-25 | 2019-10-16 | Taxis Pharmaceuticals, Inc. | Synthetic processes and intermediates |
| CA3057431A1 (en) | 2017-03-24 | 2018-09-27 | Taisho Pharmaceutical Co., Ltd. | 2(1h)-quinolinone derivative |
| US10774093B2 (en) | 2017-03-30 | 2020-09-15 | Taxis Pharmaceuticals, Inc. | Synthetic processes and synthetic intermediates |
| CN107325093B (zh) * | 2017-07-09 | 2020-06-05 | 西南科技大学 | 具抗菌活性的硫脲类化合物合成及应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH505543A (de) * | 1968-11-01 | 1971-04-15 | Ciba Geigy Ag | Schädlingsbekämpfungsmittel |
| US4028374A (en) | 1975-11-03 | 1977-06-07 | Morton-Norwich Products, Inc. | Antibacterial thiocyanatobenzothiazoles |
| JPS57149280A (en) * | 1981-03-10 | 1982-09-14 | Kyowa Hakko Kogyo Co Ltd | Amino acid derivative and its preparation |
| CN1422262A (zh) | 2000-02-07 | 2003-06-04 | 艾博特股份有限两合公司 | 2－苯并噻唑基脲衍生物及其作为蛋白激酶抑制剂的应用 |
| WO2001097786A2 (en) | 2000-06-21 | 2001-12-27 | F. Hoffmann-La Roche Ag | Benzothiazole derivatives |
| NZ526241A (en) * | 2000-12-15 | 2007-01-26 | Vertex Pharma | Gyrase inhibitors and uses thereof |
| AT345132T (de) | 2002-06-13 | 2006-12-15 | Vertex Pharma | 2-ureido-6-heteroaryl-3h-benzoimidazol-4- carbonsäurederivate und verwandte verbindungen als gyrase und/oder topoisomerase iv inhibitoren zur behandlung von bakteriellen infektionen |
| AR042956A1 (es) | 2003-01-31 | 2005-07-13 | Vertex Pharma | Inhibidores de girasa y usos de los mismos |
| WO2005037845A1 (en) | 2003-10-17 | 2005-04-28 | Rigel Pharmaceuticals, Inc. | Benzothiazole and thiazole[5,5-b] pyridine compositions and their use as ubiquitin ligase inhibitors |
| TW200621723A (en) * | 2004-09-09 | 2006-07-01 | Chugai Pharmaceutical Co Ltd | Novel imidazolidine derivative and use thereof |
| GB0612428D0 (en) * | 2006-06-22 | 2006-08-02 | Prolysis Ltd | Antibacterial agents |
-
2007
- 2007-12-13 GB GBGB0724342.1A patent/GB0724342D0/en not_active Ceased
-
2008
- 2008-12-12 US US12/747,811 patent/US8299065B2/en not_active Expired - Fee Related
- 2008-12-12 CN CN200880126437.2A patent/CN102015700B/zh not_active IP Right Cessation
- 2008-12-12 JP JP2010537517A patent/JP5539898B2/ja not_active Expired - Fee Related
- 2008-12-12 EA EA201000993A patent/EA018104B1/ru not_active IP Right Cessation
- 2008-12-12 AU AU2008334427A patent/AU2008334427B2/en not_active Ceased
- 2008-12-12 MX MX2010006428A patent/MX2010006428A/es active IP Right Grant
- 2008-12-12 NZ NZ58650808A patent/NZ586508A/xx not_active IP Right Cessation
- 2008-12-12 WO PCT/GB2008/004114 patent/WO2009074812A1/en active Application Filing
- 2008-12-12 CA CA 2709021 patent/CA2709021A1/en not_active Abandoned
- 2008-12-12 EP EP20080859786 patent/EP2231653B1/en not_active Expired - Fee Related
- 2008-12-12 KR KR20107015443A patent/KR20100105847A/ko not_active Application Discontinuation
- 2008-12-12 BR BRPI0820656-2A patent/BRPI0820656A2/pt not_active IP Right Cessation
- 2008-12-12 ES ES08859786T patent/ES2416059T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP5539898B2 (ja) | 2014-07-02 |
| MX2010006428A (es) | 2010-09-30 |
| EP2231653B1 (en) | 2013-04-03 |
| US8299065B2 (en) | 2012-10-30 |
| ES2416059T3 (es) | 2013-07-30 |
| CA2709021A1 (en) | 2009-06-18 |
| EA201000993A1 (ru) | 2011-02-28 |
| CN102015700A (zh) | 2011-04-13 |
| AU2008334427B2 (en) | 2014-06-19 |
| JP2011506417A (ja) | 2011-03-03 |
| EA018104B1 (ru) | 2013-05-30 |
| US20100305067A1 (en) | 2010-12-02 |
| NZ586508A (en) | 2012-05-25 |
| WO2009074812A1 (en) | 2009-06-18 |
| CN102015700B (zh) | 2014-12-03 |
| GB0724342D0 (en) | 2008-01-30 |
| EP2231653A1 (en) | 2010-09-29 |
| KR20100105847A (ko) | 2010-09-30 |
| AU2008334427A1 (en) | 2009-06-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK2209856T3 (da) | Aerogelsammensætninger | |
| DK2665193T3 (da) | Styrekanalallokering | |
| DK2205737T3 (da) | Mikromirer | |
| DK2158214T3 (da) | Glukagonanaloger | |
| DK2152709T3 (da) | Morphinanforbindelser | |
| DK2170321T3 (da) | Ormekur-kombination | |
| DK2121534T3 (da) | Enkeltrudelaminater | |
| DK2124668T3 (da) | Hårplejeindretning | |
| DK2195058T3 (da) | Laryngealmaske | |
| DK2514818T3 (da) | Glucoamylasevarianter | |
| DK2203551T3 (da) | Bifidobakterieart | |
| AT531723T (de) | Steviolglycosidisomere | |
| BRPI0817238A2 (pt) | Transconector | |
| AT511375T (de) | Getränkeaufbrüheinheit | |
| BRPI0815042A2 (pt) | Compostos de pirazol | |
| AT513978T (de) | Drehsteuervorrichtungsandockstation | |
| AT512633T (de) | Wirbelsäulen-verbindungselement | |
| AT544742T (de) | Insektizide arylpyrrolidine | |
| BRPI0814563A2 (pt) | Nanosuperfície | |
| BRPI0813500A2 (pt) | Compostos antivirais | |
| AT530279T (de) | Tangentialschneideeinsatz | |
| AT540954T (de) | Aminoheterocyclische verbindungen | |
| DK2514750T3 (da) | Bromphenylsubstituerede thiazolyldihydropyrimidiner | |
| DE602008002066D1 (de) | Iorekonstruktion | |
| DE602007012520D1 (de) | Katalysatorträgerwabe |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law | ||
| B06F | Objections, documents and/or translations needed after an examination request according art. 34 industrial property law | ||
| B08F | Application fees: dismissal - article 86 of industrial property law |
Free format text: REFERENTE A 10A ANUIDADE. |
|
| B08K | Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87) |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2494 DE 23-10-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |