BRPI0811264A2 - Compostos - Google Patents
CompostosInfo
- Publication number
- BRPI0811264A2 BRPI0811264A2 BRPI0811264-9A2A BRPI0811264A BRPI0811264A2 BR PI0811264 A2 BRPI0811264 A2 BR PI0811264A2 BR PI0811264 A BRPI0811264 A BR PI0811264A BR PI0811264 A2 BRPI0811264 A2 BR PI0811264A2
- Authority
- BR
- Brazil
- Prior art keywords
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/60—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GR20070100312A GR1005999B (el) | 2007-05-24 | 2007-05-24 | Ανταγωνιστες του υποδοχεα της αγγειοτενσινης με βαση 4(5) υποκατεστημενα ιμιδαζολια, συνθετικες μεθοδοι και διαδερμικη χορηγηση στην θεραπεια της υπερτασης και καρδειοαγγειακων ασθενειων |
| GB0714603A GB0714603D0 (en) | 2007-07-26 | 2007-07-26 | Compound |
| PCT/IB2008/002184 WO2008142576A2 (en) | 2007-05-24 | 2008-05-23 | 1,(3,)5-substituted imidazoles, their use in the treatment of hypertension and methods for their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0811264A2 true BRPI0811264A2 (pt) | 2014-11-04 |
Family
ID=40032238
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0811264-9A2A BRPI0811264A2 (pt) | 2007-05-24 | 2008-05-23 | Compostos |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8563586B2 (pt) |
| EP (1) | EP2162441B1 (pt) |
| JP (1) | JP2010527987A (pt) |
| KR (1) | KR20100031113A (pt) |
| CN (1) | CN101765590B (pt) |
| AU (1) | AU2008252485A1 (pt) |
| BR (1) | BRPI0811264A2 (pt) |
| CA (1) | CA2687975A1 (pt) |
| IL (1) | IL202293A0 (pt) |
| MX (1) | MX2009012755A (pt) |
| RU (1) | RU2009148050A (pt) |
| WO (1) | WO2008142576A2 (pt) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200838501A (en) | 2007-02-02 | 2008-10-01 | Theravance Inc | Dual-acting antihypertensive agents |
| TWI448284B (zh) | 2007-04-24 | 2014-08-11 | Theravance Inc | 雙效抗高血壓劑 |
| TWI406850B (zh) | 2007-06-05 | 2013-09-01 | Theravance Inc | 雙效苯并咪唑抗高血壓劑 |
| US20100216854A1 (en) * | 2007-08-01 | 2010-08-26 | Eldrug S.A. | 1,3 and 1,3,5 substituted imidazoles as antihypertensives |
| JP2010538071A (ja) | 2007-09-07 | 2010-12-09 | セラヴァンス， インコーポレーテッド | 二重作用性降圧剤 |
| US8212052B2 (en) | 2007-12-11 | 2012-07-03 | Theravance, Inc. | Dual-acting benzoimidazole antihypertensive agents |
| EP2297113A1 (en) | 2008-04-29 | 2011-03-23 | Theravance, Inc. | Dual-acting antihypertensive agents |
| WO2010011821A2 (en) | 2008-07-24 | 2010-01-28 | Theravance, Inc. | Dual-acting antihypertensive agents |
| WO2011005674A1 (en) | 2009-07-07 | 2011-01-13 | Theravance, Inc. | Dual-acting pyrazole antihypertensive agents |
| ES2441419T3 (es) | 2009-07-22 | 2014-02-04 | Theravance, Inc. | Agentes antihipertensivos de doble acción basados en oxazol |
| HUP0900788A2 (en) * | 2009-12-16 | 2011-11-28 | Sanofi Aventis | Process for producing 4-bromomethyl-biphenyl derivatives |
| US8481549B2 (en) | 2010-01-19 | 2013-07-09 | Theravance, Inc. | Dual-acting thiophene, pyrrole, thiazole and furan antihypertensive agents |
| WO2012048022A2 (en) * | 2010-10-05 | 2012-04-12 | Nova Southeastern University | Methods and compositions for therapeutic modulation of aldosterone levels in heart disease |
| ES2665093T3 (es) * | 2011-07-22 | 2018-04-24 | Cambrex Karlskoga Ab | Nuevos procedimiento de preparación de imidazoles 4-sustituidos |
| US9505737B2 (en) | 2013-01-11 | 2016-11-29 | Corsair Pharma, Inc. | Treprostinil derivative compounds and methods of using same |
| WO2016031928A1 (ja) * | 2014-08-29 | 2016-03-03 | 東京応化工業株式会社 | イミダゾール化合物、金属表面処理液、金属の表面処理方法、及び積層体の製造方法 |
| CN104892535B (zh) * | 2015-06-03 | 2017-03-22 | 启东东岳药业有限公司 | 5‑(4’‑甲基‑[1,1’‑联苯]‑2‑基)‑1氢‑四唑的合成方法 |
| TWI776812B (zh) | 2016-06-02 | 2022-09-11 | 荷蘭商菲林公司 | 血管收縮素-1-受體拮抗劑 |
| JP6979844B2 (ja) * | 2017-10-06 | 2021-12-15 | 株式会社シマノ | 回転伝達機構、及びそれを備えた魚釣用スピニングリール |
| JP7138685B2 (ja) * | 2020-10-26 | 2022-09-16 | コルセア ファーマ インコーポレイテッド | トレプロスチニル誘導体化合物およびその使用方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL95975A (en) * | 1989-10-24 | 1997-06-10 | Takeda Chemical Industries Ltd | N-benzyl- 2-alkylbenzimidazole derivatives, their production and pharmaceutical compositions containing them |
| US5250554A (en) * | 1989-10-24 | 1993-10-05 | Takeda Chemical Industries, Ltd. | Benzimidazole derivatives useful as angiotensin II inhibitors |
| CA2028925A1 (en) | 1989-11-06 | 1991-05-07 | Gerald R. Girard | Substituted n-(imidazolyl)alkyl alanine derivatives |
| FR2689508B1 (fr) | 1992-04-01 | 1994-06-17 | Fournier Ind & Sante | Derives de l'imidazole, leur procede de preparation et leur application en therapeutique. |
| JPH0687833A (ja) * | 1992-07-21 | 1994-03-29 | Sankyo Co Ltd | ビニルイミダゾール誘導体 |
| EP1871764A1 (en) | 2005-04-01 | 2008-01-02 | LEK Pharmaceuticals D.D. | A synthesis of 4-bromomethyl-2'-formylbiphenyl and 4-bromomethyl-2'- hydroxymethylbiphenyl and its use in preparation of angiotensin ii antagonists |
| US20100216854A1 (en) * | 2007-08-01 | 2010-08-26 | Eldrug S.A. | 1,3 and 1,3,5 substituted imidazoles as antihypertensives |
-
2008
- 2008-05-23 RU RU2009148050/04A patent/RU2009148050A/ru unknown
- 2008-05-23 KR KR1020097027055A patent/KR20100031113A/ko not_active Application Discontinuation
- 2008-05-23 AU AU2008252485A patent/AU2008252485A1/en not_active Abandoned
- 2008-05-23 EP EP08789111.5A patent/EP2162441B1/en not_active Not-in-force
- 2008-05-23 BR BRPI0811264-9A2A patent/BRPI0811264A2/pt not_active Application Discontinuation
- 2008-05-23 CA CA002687975A patent/CA2687975A1/en not_active Abandoned
- 2008-05-23 CN CN200880100474.6A patent/CN101765590B/zh not_active Expired - Fee Related
- 2008-05-23 US US12/601,402 patent/US8563586B2/en not_active Expired - Fee Related
- 2008-05-23 JP JP2010508929A patent/JP2010527987A/ja active Pending
- 2008-05-23 WO PCT/IB2008/002184 patent/WO2008142576A2/en active Application Filing
- 2008-05-23 MX MX2009012755A patent/MX2009012755A/es not_active Application Discontinuation
-
2009
- 2009-11-23 IL IL202293A patent/IL202293A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2162441B1 (en) | 2016-01-06 |
| CN101765590B (zh) | 2015-11-25 |
| WO2008142576A2 (en) | 2008-11-27 |
| IL202293A0 (en) | 2010-06-16 |
| CN101765590A (zh) | 2010-06-30 |
| JP2010527987A (ja) | 2010-08-19 |
| CA2687975A1 (en) | 2008-11-27 |
| KR20100031113A (ko) | 2010-03-19 |
| MX2009012755A (es) | 2010-04-30 |
| US8563586B2 (en) | 2013-10-22 |
| US20100166837A1 (en) | 2010-07-01 |
| RU2009148050A (ru) | 2011-06-27 |
| EP2162441A2 (en) | 2010-03-17 |
| AU2008252485A1 (en) | 2008-11-27 |
| WO2008142576A3 (en) | 2009-05-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] | ||
| B350 | Update of information on the portal [chapter 15.35 patent gazette] |