FR2555571B1 - Derives du naphtalene, leur procede de preparation et leur application dans le domaine therapeutique - Google Patents

Derives du naphtalene, leur procede de preparation et leur application dans le domaine therapeutique

Info

Publication number
FR2555571B1
FR2555571B1 FR8318917A FR8318917A FR2555571B1 FR 2555571 B1 FR2555571 B1 FR 2555571B1 FR 8318917 A FR8318917 A FR 8318917A FR 8318917 A FR8318917 A FR 8318917A FR 2555571 B1 FR2555571 B1 FR 2555571B1
Authority
FR
France
Prior art keywords
application
preparation process
naphthalene derivatives
therapeutic field
therapeutic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8318917A
Other languages
English (en)
Other versions
FR2555571A1 (fr
Inventor
Braham Shroot
Jacques Eustache
Martine Bouclier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Galderma Research and Development SNC
Original Assignee
Centre International de Recherches Dermatologiques Galderma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR8318917A priority Critical patent/FR2555571B1/fr
Application filed by Centre International de Recherches Dermatologiques Galderma filed Critical Centre International de Recherches Dermatologiques Galderma
Priority to GB08429900A priority patent/GB2150563B/en
Priority to GB08429901A priority patent/GB2150564B/en
Priority to DE3443231A priority patent/DE3443231C2/de
Priority to AU35935/84A priority patent/AU582556B2/en
Priority to AT0376184A priority patent/AT395583B/de
Priority to AT0376284A priority patent/AT394362B/de
Priority to JP59248831A priority patent/JPH0678275B2/ja
Priority to DE3443230A priority patent/DE3443230C2/de
Priority to NL8403607A priority patent/NL193819C/nl
Priority to CH5657/84A priority patent/CH663952A5/fr
Priority to NL8403608A priority patent/NL193855C/nl
Priority to IT23748/84A priority patent/IT1177330B/it
Priority to JP59248830A priority patent/JPS60155140A/ja
Priority to BE0/214062A priority patent/BE901139A/fr
Priority to IT8423747A priority patent/IT1209603B/it
Priority to CH5658/84A priority patent/CH662559A5/fr
Priority to CA000468730A priority patent/CA1247123A/fr
Priority to BE0/214063A priority patent/BE901140A/fr
Priority to AU35934/84A priority patent/AU573652B2/en
Priority to CA000468729A priority patent/CA1247132A/fr
Priority to US06/675,701 priority patent/US4581380A/en
Priority to US06/675,700 priority patent/US4666941A/en
Publication of FR2555571A1 publication Critical patent/FR2555571A1/fr
Publication of FR2555571B1 publication Critical patent/FR2555571B1/fr
Application granted granted Critical
Priority to US07/039,463 priority patent/US4886907A/en
Priority to US07/407,739 priority patent/US5041639A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/34—Monohydroxylic alcohols containing six-membered aromatic rings and other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
    • C07C39/17—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings containing other rings in addition to the six-membered aromatic rings, e.g. cyclohexylphenol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/164—Unsaturated ethers containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/30—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation
    • C07C45/305—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation with halogenochromate reagents, e.g. pyridinium chlorochromate
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/546—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/782—Ketones containing a keto group bound to a six-membered aromatic ring polycyclic
    • C07C49/792—Ketones containing a keto group bound to a six-membered aromatic ring polycyclic containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/33—Polycyclic acids
    • C07C63/49—Polycyclic acids containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • C07C65/17—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
    • C07C65/26—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic containing rings other than six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/02—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings containing insect repellants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/007—Preparations for dry skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/008—Preparations for oily skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/02—Preparations for cleaning the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
FR8318917A 1983-11-28 1983-11-28 Derives du naphtalene, leur procede de preparation et leur application dans le domaine therapeutique Expired FR2555571B1 (fr)

Priority Applications (25)

Application Number Priority Date Filing Date Title
FR8318917A FR2555571B1 (fr) 1983-11-28 1983-11-28 Derives du naphtalene, leur procede de preparation et leur application dans le domaine therapeutique
CA000468729A CA1247132A (fr) 1983-11-28 1984-11-27 Derives 2,6 disubstitues du naphtalene et leur procede de preparation
DE3443231A DE3443231C2 (de) 1983-11-28 1984-11-27 Polysubstituierte Naphthalinderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische und kosmetische Zubereitungen
AU35935/84A AU582556B2 (en) 1983-11-28 1984-11-27 2,6-disubstituted derivatives of naphthalene, a process for preparing them and their use in the pharmaceutical and cosmetic fields
AT0376184A AT395583B (de) 1983-11-28 1984-11-27 Verfahren zur herstellung neuer polysubstituierter naphthalinderivate
AT0376284A AT394362B (de) 1983-11-28 1984-11-27 Verfahren zur herstellung von neuen 2,6-disubstituierten naphthalin-derivaten
JP59248831A JPH0678275B2 (ja) 1983-11-28 1984-11-27 ポリ置換ナフタレン化合物、その製造方法およびこれを含有する医薬および化粧料組成物
DE3443230A DE3443230C2 (de) 1983-11-28 1984-11-27 2,6-disubstituierte Naphthalin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung auf dem pharmazeutischen und kosmetischen Gebiet
NL8403607A NL193819C (nl) 1983-11-28 1984-11-27 Naftaleenderivaten alsmede farmaceutische en cosmetische preparaten, die deze derivaten bevatten.
CH5657/84A CH663952A5 (fr) 1983-11-28 1984-11-27 Derives poly substitues du naphtalene, leur procede de preparation et compositions pharmaceutiques et cosmetiques contenant ces derives.
NL8403608A NL193855C (nl) 1983-11-28 1984-11-27 Naftaleenderivaten alsmede farmaceutische en cosmetische preparaten, die deze derivaten bevatten.
IT23748/84A IT1177330B (it) 1983-11-28 1984-11-27 Derivati polisostituiti di naftalene, relativo procedimento di preparazione e uso in campo farmaceutico e cosmetico
GB08429900A GB2150563B (en) 1983-11-28 1984-11-27 Polysubstituted derivatives of naphthalene a process for preparing them and their use in the pharmaceutical and cosmetic fields
JP59248830A JPS60155140A (ja) 1983-11-28 1984-11-27 ナフタレン誘導体化合物、その製造方法及びこれを含有する医薬及び化粧料組成物
AU35934/84A AU573652B2 (en) 1983-11-28 1984-11-27 Polysubstituted derivatives of naphthalene
CH5658/84A CH662559A5 (fr) 1983-11-28 1984-11-27 Derives 2,6-disubstitues du naphtalene, leur procede de preparation et composition pharmaceutique ou cosmetique les contenant.
CA000468730A CA1247123A (fr) 1983-11-28 1984-11-27 Derives polysubstitues du naphtalene et leur procede de preparation
BE0/214063A BE901140A (fr) 1983-11-28 1984-11-27 Derives poly-substitues du naphtalene, leur procede de preparation et leur application dans les domaines pharmaceutiques et cosmetique.
IT8423747A IT1209603B (it) 1983-11-28 1984-11-27 Derivati 2,6-disostituiti di naftalene, procedimento per prepararli e loro uso nel campo farmaceutico e cosmetico.
GB08429901A GB2150564B (en) 1983-11-28 1984-11-27 2, 6-disubstituted derivatives of naphthalene a process for preparing them and their use in the pharmaceutical and cosmetic fields
BE0/214062A BE901139A (fr) 1983-11-28 1984-11-27 Derives 2,6-disubstitues du naphtalene, leur procede de preparation et leur application dans les domaines pharmaceutique et cosmetique.
US06/675,701 US4581380A (en) 1983-11-28 1984-11-28 2,6-disubstituted naphthalene derivatives, a process for preparing the same and pharmaceutical and cosmetic compositions containing the same
US06/675,700 US4666941A (en) 1983-11-28 1984-11-28 Pharmaceutical uses of substituted 6(5,6,7,8)tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-2-naphthoic acid and its esters
US07/039,463 US4886907A (en) 1983-11-28 1987-04-17 Polysubstituted derivatives of naphthalene, their process of preparation and their application in the cosmetic and pharmaceutical fields
US07/407,739 US5041639A (en) 1983-11-28 1989-09-15 Polysubstituted derivatives of naphtalene, their process of preparation and their application in the cosmetic and pharmaceutical fields

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8318917A FR2555571B1 (fr) 1983-11-28 1983-11-28 Derives du naphtalene, leur procede de preparation et leur application dans le domaine therapeutique

Publications (2)

Publication Number Publication Date
FR2555571A1 FR2555571A1 (fr) 1985-05-31
FR2555571B1 true FR2555571B1 (fr) 1986-11-28

Family

ID=9294579

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8318917A Expired FR2555571B1 (fr) 1983-11-28 1983-11-28 Derives du naphtalene, leur procede de preparation et leur application dans le domaine therapeutique

Country Status (12)

Country Link
US (4) US4666941A (fr)
JP (2) JPH0678275B2 (fr)
AT (2) AT394362B (fr)
AU (2) AU573652B2 (fr)
BE (2) BE901139A (fr)
CA (2) CA1247123A (fr)
CH (2) CH663952A5 (fr)
DE (2) DE3443230C2 (fr)
FR (1) FR2555571B1 (fr)
GB (2) GB2150564B (fr)
IT (2) IT1209603B (fr)
NL (2) NL193855C (fr)

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FR2492373A1 (fr) * 1980-10-21 1982-04-23 Cird Adducts de dihydroxy-1,8 anthrone-9 et leur utilisation en medecine humaine ou veterinaire et en cosmetique
FR2555571B1 (fr) * 1983-11-28 1986-11-28 Interna Rech Dermatolo Centre Derives du naphtalene, leur procede de preparation et leur application dans le domaine therapeutique
DE3434946A1 (de) * 1984-09-22 1986-04-03 Basf Ag, 6700 Ludwigshafen Diarylacetylene, ihre herstellung und verwendung
LU85562A1 (fr) * 1984-10-01 1986-06-11 Oreal Nouveaux derives 1-substitutes du methoxy-4 trimethyl-2, 3, 6 benzene,leur procede de preparation et compositions medicamenteuse et cosmetique les contenant
FR2573755B1 (fr) * 1984-11-27 1988-04-22 Cird Derives polysubstitues du naphtalene, leur procede de preparation et leur application dans les domaines pharmaceutique et cosmetique
LU85849A1 (fr) * 1985-04-11 1986-11-05 Cird Derives benzonaphtaleniques,leur procede de preparation et leur application dans les domaines pharmaceutiques et cosmetiques
IL80270A0 (en) * 1985-10-11 1987-01-30 Cird Naphthalene derivatives,their preparation and pharmaceutical compositions containing them
FR2601359B1 (fr) * 1986-07-09 1988-10-28 Cird Nouveaux derives bicycliques naphtaleniques, leur procede de preparation et leur utilisation en medecine humaine et veterinaire et en cosmetique.
DE3602473A1 (de) * 1986-01-28 1987-07-30 Basf Ag Vinylphenolderivate, ihre herstellung und verwendung
US4795629A (en) * 1987-07-06 1989-01-03 Chesebrough-Pond's Inc. Crosslinking of hair thiols using cystamine
AU618590B2 (en) * 1988-04-11 1992-01-02 Allergan, Inc. Tetralin esters of phenols or benzoic acids having retinoid like activity
MY105521A (en) * 1989-04-17 1994-10-31 Healthpoint Ltd Moisturizing vehicle for topical application of vitamin a acid.
FR2670482A1 (fr) * 1990-12-14 1992-06-19 Atochem Derives des acides naphtyloxy benzouiques et naphtouiques leur procede de synthese.
DE4329379C1 (de) * 1993-09-01 1995-02-16 Beiersdorf Ag Gegen unreine Haut und milde Formen der Akne wirksame Zubereitungen mit einem Gehalt an Wollwachssäuren
FR2767525B1 (fr) 1997-08-21 1999-11-12 Cird Galderma Derives biphenyliques substitues par un radical aromatique ou heteroaromatique et compositions pharmaceutiques et cosmetiques les contenant
US6608212B1 (en) * 2002-06-04 2003-08-19 Pfizer, Inc. Process for preparing vinylaromatic compounds
US20040259744A1 (en) * 2003-12-19 2004-12-23 Meidong Yang Skin and hair cleansers containing sulfur
FR2910321B1 (fr) 2006-12-21 2009-07-10 Galderma Res & Dev S N C Snc Gel creme comprenant au moins un retinoide et du peroxyde de benzole
FR2910320B1 (fr) 2006-12-21 2009-02-13 Galderma Res & Dev S N C Snc Emulsion comprenant au moins un retinoide et du peroxyde de benzole
FR2931661B1 (fr) 2008-05-30 2010-07-30 Galderma Res & Dev Nouvelles compositions depigmentantes sous forme d'une composition anhydre sans vaseline et sans elastomere comprenant un derive phenolique solubilise et un retinoide.
TW201028142A (en) * 2008-10-30 2010-08-01 Biogen Idec Inc Heterobicyclic sphingosine 1-phosphate analogs
ES2466695T3 (es) 2008-10-30 2014-06-11 Biogen Idec Ma Inc. Análogos de esfingosina 1-fosfato de arilo bicíclico
US9181191B2 (en) 2008-10-30 2015-11-10 Biogen Ma Inc. Heterobicyclic sphingosine 1-phosphate analogs
UA107360C2 (en) 2009-08-05 2014-12-25 Biogen Idec Inc Bicyclic aryl sphingosine 1-phosphate analogs
EP3150590B1 (fr) 2011-02-07 2019-10-16 Biogen MA Inc. Agents de modulation s1p
EP3152190A4 (fr) 2014-06-04 2018-03-28 Haro Pharmaceutical Inc. Composés bi-polycycliques de 18 à 20 éléments
JP6298022B2 (ja) 2015-08-05 2018-03-20 信越化学工業株式会社 高分子化合物、ポジ型レジスト組成物、積層体、及びレジストパターン形成方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3499751A (en) * 1966-07-05 1970-03-10 Givaudan Corp Method and composition for controlling weeds with acylated tetrahydronaphthalene
US4326055A (en) * 1977-12-22 1982-04-20 Hoffmann-La Roche Inc. Stilbene derivatives
DK159967C (da) * 1977-12-22 1991-06-03 Hoffmann La Roche Analogifremgangsmaade til fremstilling af terapeutisk aktive stilbenderivater
US4454341A (en) * 1983-03-03 1984-06-12 Sri International Naphthyl or tetrahydronaphthyl-substituted naphthoic acid and derivatives
FR2555571B1 (fr) * 1983-11-28 1986-11-28 Interna Rech Dermatolo Centre Derives du naphtalene, leur procede de preparation et leur application dans le domaine therapeutique

Also Published As

Publication number Publication date
JPS60155141A (ja) 1985-08-15
ATA376184A (de) 1992-06-15
ATA376284A (de) 1991-09-15
CA1247123A (fr) 1988-12-20
FR2555571A1 (fr) 1985-05-31
NL8403607A (nl) 1985-06-17
BE901139A (fr) 1985-05-28
US4666941A (en) 1987-05-19
JPH0583528B2 (fr) 1993-11-26
DE3443231A1 (de) 1985-06-05
GB2150563A (en) 1985-07-03
IT8423748A1 (it) 1986-05-27
NL193855C (nl) 2001-01-03
IT8423748A0 (it) 1984-11-27
CH663952A5 (fr) 1988-01-29
AT394362B (de) 1992-03-25
JPS60155140A (ja) 1985-08-15
US4886907A (en) 1989-12-12
CH662559A5 (fr) 1987-10-15
BE901140A (fr) 1985-05-28
AU3593584A (en) 1985-06-06
IT1209603B (it) 1989-08-30
US4581380A (en) 1986-04-08
AU582556B2 (en) 1989-04-06
DE3443231C2 (de) 1994-04-07
NL193855B (nl) 2000-09-01
GB8429901D0 (en) 1985-01-03
NL193819C (nl) 2000-12-04
US5041639A (en) 1991-08-20
JPH0678275B2 (ja) 1994-10-05
NL8403608A (nl) 1985-06-17
GB2150564B (en) 1987-05-13
GB2150563B (en) 1987-04-15
IT1177330B (it) 1987-08-26
GB2150564A (en) 1985-07-03
NL193819B (nl) 2000-08-01
IT8423747A0 (it) 1984-11-27
AU573652B2 (en) 1988-06-16
GB8429900D0 (en) 1985-01-03
DE3443230C2 (de) 1994-11-24
DE3443230A1 (de) 1985-06-05
AU3593484A (en) 1985-06-06
AT395583B (de) 1993-01-25
CA1247132A (fr) 1988-12-20

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