FR2550940B1 - Composition cosmetique ou pharmaceutique sous forme aqueuse ou anhydre contenant, en tant que produit gras, un polyether oligomere - Google Patents

Composition cosmetique ou pharmaceutique sous forme aqueuse ou anhydre contenant, en tant que produit gras, un polyether oligomere

Info

Publication number
FR2550940B1
FR2550940B1 FR8413253A FR8413253A FR2550940B1 FR 2550940 B1 FR2550940 B1 FR 2550940B1 FR 8413253 A FR8413253 A FR 8413253A FR 8413253 A FR8413253 A FR 8413253A FR 2550940 B1 FR2550940 B1 FR 2550940B1
Authority
FR
France
Prior art keywords
cosmetic
aqueous
pharmaceutical composition
form containing
anhydrous form
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8413253A
Other languages
English (en)
Other versions
FR2550940A1 (fr
Inventor
Bernard Jacquet
Quintino Gaetani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LOreal SA
Original Assignee
LOreal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LOreal SA filed Critical LOreal SA
Publication of FR2550940A1 publication Critical patent/FR2550940A1/fr
Application granted granted Critical
Publication of FR2550940B1 publication Critical patent/FR2550940B1/fr
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0212Face masks
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/38Percompounds, e.g. peracids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/39Derivatives containing from 2 to 10 oxyalkylene groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/03Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/04Saturated ethers
    • C07C43/10Saturated ethers of polyhydroxy compounds
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/04Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers only
    • C08G65/06Cyclic ethers having no atoms other than carbon and hydrogen outside the ring
    • C08G65/16Cyclic ethers having four or more ring atoms
    • C08G65/18Oxetanes
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/04Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers only
    • C08G65/06Cyclic ethers having no atoms other than carbon and hydrogen outside the ring
    • C08G65/16Cyclic ethers having four or more ring atoms
    • C08G65/20Tetrahydrofuran
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02Preparations containing skin colorants, e.g. pigments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02Preparations containing skin colorants, e.g. pigments
    • A61Q1/08Preparations containing skin colorants, e.g. pigments for cheeks, e.g. rouge
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02Preparations containing skin colorants, e.g. pigments
    • A61Q1/10Preparations containing skin colorants, e.g. pigments for eyes, e.g. eyeliner, mascara
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/14Preparations for removing make-up
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/007Preparations for dry skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/04Preparations for care of the skin for chemically tanning the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/02Preparations for cleaning the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/10Preparations for permanently dyeing the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/12Preparations containing hair conditioners
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/04Dandruff

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Polymers & Plastics (AREA)
  • Emergency Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
FR8413253A 1983-08-30 1984-08-27 Composition cosmetique ou pharmaceutique sous forme aqueuse ou anhydre contenant, en tant que produit gras, un polyether oligomere Expired FR2550940B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU84979A LU84979A1 (fr) 1983-08-30 1983-08-30 Composition cosmetique ou pharmaceutique sous forme aqueuse ou anhydre dont la phase grasse contient un polyether oligomere et polyethers oligomeres nouveaux

Publications (2)

Publication Number Publication Date
FR2550940A1 FR2550940A1 (fr) 1985-03-01
FR2550940B1 true FR2550940B1 (fr) 1987-11-27

Family

ID=19730140

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8413253A Expired FR2550940B1 (fr) 1983-08-30 1984-08-27 Composition cosmetique ou pharmaceutique sous forme aqueuse ou anhydre contenant, en tant que produit gras, un polyether oligomere

Country Status (6)

Country Link
US (1) US4608392A (fr)
JP (1) JPS6078914A (fr)
DE (1) DE3431755C2 (fr)
FR (1) FR2550940B1 (fr)
GB (1) GB2145627B (fr)
LU (1) LU84979A1 (fr)

Families Citing this family (426)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5017367A (en) * 1984-10-01 1991-05-21 Stojkoski Radmila G Skin treatment preparation
LU85789A1 (fr) * 1985-02-26 1986-09-02 Oreal Utilisation dans les domaines therapeutique et cosmetique d'une solution anhydre de peroxyde d'hydrogene
IT1183530B (it) * 1985-03-29 1987-10-22 Monteluos S P A Composizioni per cosmesi comprendente perfluoropolieteri
US4797272A (en) * 1985-11-15 1989-01-10 Eli Lilly And Company Water-in-oil microemulsions for cosmetic uses
DE3612305A1 (de) * 1986-04-11 1987-10-22 Roehm Pharma Gmbh Fluessige arzneiform zur therapie der psoriasis auf basis filmbildender polymere
LU86393A1 (fr) * 1986-04-16 1987-12-07 Oreal Composition anti-acneique stable a base d'erythromycine
US4840788A (en) * 1986-07-15 1989-06-20 Ici Americas Inc. Nonalcoholic sunscreen gel
JP2622955B2 (ja) * 1986-07-29 1997-06-25 エイボン プロダクツ インコ−ポレイテツド 無水化粧品
US4749563A (en) * 1986-12-08 1988-06-07 Charles Of The Ritz Group Ltd. Moisture-resistant skin treatment compositions
US4883654A (en) * 1987-01-09 1989-11-28 Young Deborah A Cosmetic preparation
US5013763A (en) * 1987-11-30 1991-05-07 The Andrew Jergens Company Wash-off-resistant skin preparation
US5141349A (en) * 1988-05-26 1992-08-25 Procter & Gamble Company Method and apparatus for treating the blade of a razor head
US5019376A (en) * 1989-03-13 1991-05-28 S. C. Johnson & Son, Inc. Sparkling pearlescent personal care compositions
US5470567A (en) * 1989-08-24 1995-11-28 Bristol Myers Squibb Company Synergistic skin depigmentation composition
US5002760A (en) * 1989-10-02 1991-03-26 Katzev Phillip K Retinol skin care composition
US5204105A (en) * 1990-04-10 1993-04-20 Chanel, Inc. Cosmetic composition
US5336692A (en) * 1990-06-28 1994-08-09 Medicis Pharmaceutical Corporation Ointment base and method of use
US5273739A (en) * 1990-12-07 1993-12-28 Jim Baral Composition and treatment for darkening hair color
GB9106365D0 (en) * 1991-03-26 1991-05-15 Bioglan Lab Ltd An emollient for use with ultraviolet light
US5460808A (en) * 1991-05-15 1995-10-24 Chanel, Inc. Mascara composition
US5254331A (en) * 1991-09-12 1993-10-19 Chanel, Inc. Skin cream composition
FR2681781A1 (fr) * 1991-09-30 1993-04-02 Oreal Composition cosmetique anhydre de maquillage comprenant une phase grasse et procede de traitement cosmetique utilisant cette composition.
US5215759A (en) * 1991-10-01 1993-06-01 Chanel, Inc. Cosmetic composition
US5431913A (en) * 1992-01-24 1995-07-11 Phillips; Eva J. Skin cleansing and exfoliant composition and method of treating skin
US5248494A (en) * 1992-06-10 1993-09-28 Young Pharmaceuticals Inc. Method of reducing anthralin induced inflammation and staining
US5391373A (en) * 1992-07-01 1995-02-21 Chanel, Inc. Skin cream composition
US5686086A (en) * 1992-07-13 1997-11-11 Shiseido Co., Ltd. External skin treatment composition
ATE235883T1 (de) * 1992-07-13 2003-04-15 Shiseido Co Ltd Zusammensetzung für dermatologische zubereitung
US5962000A (en) * 1992-07-13 1999-10-05 Shiseido Company, Ltd. External skin treatment composition
US5242433A (en) * 1992-12-07 1993-09-07 Creative Products Resource Associates, Ltd. Packaging system with in-tandem applicator pads for topical drug delivery
US5460620A (en) * 1992-07-31 1995-10-24 Creative Products Resource, Inc. Method of applying in-tandem applicator pads for transdermal delivery of a therapeutic agent
WO1994013257A1 (fr) * 1992-12-16 1994-06-23 Creative Products Resource Associates, Ltd. Lotion occlusive ou semi-occlusive pour le traitement de maladies ou de desordres cutanes
US5393520A (en) * 1993-06-11 1995-02-28 Incando; Peter A. Hair treatment method and composition
US5413124A (en) * 1993-08-13 1995-05-09 Incando; Peter A. Hair weft and extension method and article
US5352441A (en) * 1993-09-09 1994-10-04 Chanel, Inc. Powder-based lip liner cosmetic composition
US5658580A (en) * 1993-09-09 1997-08-19 Chanel, Inc. Skin cream composition
GB2281697A (en) * 1993-09-14 1995-03-15 Euro Celtique Sa Laxative compositions in capsules
US5866149A (en) * 1993-12-10 1999-02-02 L'oreal Composition for making up the eyelashes and the eyebrows stabilized oxyethylenated derivatives
US5456851A (en) * 1994-04-07 1995-10-10 Johnson & Johnson Consumer Products, Inc. Ketoconazole shampoo containing butylated hydroxytoluene or butylated hydroxyanisole
US5470884A (en) * 1994-05-19 1995-11-28 Procter & Gamble Anti-acne compositions
US5449519C1 (en) * 1994-08-09 2001-05-01 Revlon Consumer Prod Corp Cosmetic compositions having keratolytic and anti-acne activity
WO1996006620A2 (fr) * 1994-08-29 1996-03-07 Wake Forest University Analogues de lipides pour le traitement d'infections virales
US7135584B2 (en) * 1995-08-07 2006-11-14 Wake Forest University Lipid analogs for treating viral infections
US5646106A (en) * 1994-12-30 1997-07-08 Rhone-Poulenc Specialty Chemicals Asia Pacific Pte Ltd Cold pearlizing concentrates
US5560873A (en) * 1994-12-30 1996-10-01 Chen; Pu Mild cold pearlizing concentrates
US6579516B1 (en) 1995-06-13 2003-06-17 Zahra Mansouri Methods of delivering materials into the skin, and compositions used therein
US5571503A (en) * 1995-08-01 1996-11-05 Mausner; Jack Anti-pollution cosmetic composition
US5601810A (en) * 1995-11-22 1997-02-11 Chanel, Inc. Mascara composition
US5932553A (en) * 1996-07-18 1999-08-03 The Regents Of The University Of California Illudin analogs useful as antitumor agents
US5723632A (en) * 1996-08-08 1998-03-03 Mgi Pharma, Inc. Total synthesis of antitumor acylfulvenes
US5770206A (en) * 1996-12-19 1998-06-23 C&D Master Enterprizes Ltd Body oils and method for making the same
US6312450B1 (en) 1997-05-20 2001-11-06 Natural Vision Center, Inc. System and method for improving the appearance of skin
US5962504A (en) 1997-09-08 1999-10-05 Georgetown University Substituted 2-pyrrolidinone activators of PKC
US6486214B1 (en) 1997-09-10 2002-11-26 Rutgers, The State University Of New Jersey Polyanhydride linkers for production of drug polymers and drug polymer compositions produced thereby
CA2282461C (fr) * 1997-12-29 2004-04-20 John D. Buynak Derives d'acide penicillanique 2.beta.-substitue-6-alkylidene utilises comme inhibiteurs de la beta-lactamase
US6432941B1 (en) 1998-01-20 2002-08-13 Parker Hughes Institute Vanadium compounds for treating cancer
US6051603A (en) 1998-01-20 2000-04-18 Wayne Hughes Institute Vanadium (IV) metallocene complexes having sperm motility inhibiting activity
US6245808B1 (en) 1998-11-05 2001-06-12 Parker Hughes Institute Oxy-vanadium (IV) complexes having spermicidal activity
US7141603B2 (en) * 1999-02-19 2006-11-28 The Regents Of The University California Antitumor agents
US6025328A (en) 1998-02-20 2000-02-15 The Regents Of The University Of California Antitumor agents
US6355678B1 (en) * 1998-06-29 2002-03-12 Parker Hughes Institute Inhibitors of the EGF-receptor tyrosine kinase and methods for their use
US6800649B1 (en) * 1998-06-30 2004-10-05 Parker Hughes Institute Method for inhibiting c-jun expression using JAK-3 inhibitors
US6589537B2 (en) * 1999-02-11 2003-07-08 Marie Harbeck Infant skin care composition
US6193987B1 (en) * 1999-02-11 2001-02-27 Marie Helena Harbeck Lubricating composition for hands and skin
US6080747A (en) * 1999-03-05 2000-06-27 Hughes Institute JAK-3 inhibitors for treating allergic disorders
EP1159279B1 (fr) 1999-03-09 2002-10-16 PHARMACIA & UPJOHN COMPANY AGENTS ANTIVIRAUX DE 4-OXO-4,7-DIHYDRO-THIENO 2,3-b]PYRIDINE-5-CARBOXAMIDES
US6258820B1 (en) 1999-03-19 2001-07-10 Parker Hughes Institute Synthesis and anti-tumor activity of 6,7-dialkoxy-4-phenylamino-quinazolines
US6306897B1 (en) 1999-03-19 2001-10-23 Parker Hughes Institute Calanolides for inhibiting BTK
US6407091B1 (en) * 1999-04-15 2002-06-18 Research Corporation Technologies, Inc. β-lactamase inhibiting compounds
JP4698843B2 (ja) * 1999-05-17 2011-06-08 エーザイ インコーポレイテッド 生体活性剤の改良された細胞取り込み
US6930101B1 (en) 1999-05-17 2005-08-16 The Regents Of The University Of California Thiazolopyrimidines useful as TNFα inhibitors
US6551998B1 (en) * 1999-06-22 2003-04-22 University Of Louisville Research Foundation, Inc. Antimicrobial agents
US6254594B1 (en) 1999-07-30 2001-07-03 Quadrivium, Llc Disposable light source for photothermal treatment of human tissue
US7026469B2 (en) * 2000-10-19 2006-04-11 Wake Forest University School Of Medicine Compositions and methods of double-targeting virus infections and cancer cells
US6670341B1 (en) 1999-10-28 2003-12-30 Wake Forest University Health Sciences Compositions and methods for double-targeting virus infections and targeting cancer cells
US6740650B2 (en) 1999-10-29 2004-05-25 Rutgers, The State University Of New Jersey Heterocyclic cytotoxic agents
AU1608801A (en) 1999-11-15 2001-05-30 Parker Hughes Institute Diamino platinum (ii) antitumor complexes
US6649654B1 (en) 1999-11-23 2003-11-18 The Regents Of The University Of California Methods for identifying and using IKK inhibitors
US6589992B2 (en) 1999-11-30 2003-07-08 Parker Hughes Institute Inhibiting collagen-induced platelet aggregation
US6355280B1 (en) * 2000-02-28 2002-03-12 I.M.S. Cosmetics Composition for reducing cell apoptosis containing avocado and soybean lipid unsaponifiables
WO2001070742A1 (fr) 2000-03-21 2001-09-27 Pharmacia & Upjohn Company 4-hydroxy-1,8-naphtyridine-3-carboxamides en tant qu'agents antiviraux
JP2003531195A (ja) 2000-03-21 2003-10-21 ファルマシア・アンド・アップジョン・カンパニー 抗ウイルス剤としての4−ヒドロキシシンノリン−3−カルボキサミド
NZ521522A (en) 2000-03-21 2004-08-27 Upjohn Co 4-oxo-1,4-dihydro[1,8]naphthyridine-3-carboxamides useful as antiviral agents
FR2811228B1 (fr) * 2000-07-07 2002-10-25 Lvmh Rech Utilisation d'oligosaccharides ou d'extraits de plantes en contenant comme agent cosmetique ou dermatologique notamment pour stimuler la production de beta-endorphine dans la peau
US6682892B2 (en) * 2000-07-13 2004-01-27 Pharmacia & Upjohn Company Method for treating herpes viruses
US6696441B1 (en) 2000-08-11 2004-02-24 The Regents Of The University Of California Inhibition of p53-induced stress response
US6689767B2 (en) 2000-09-29 2004-02-10 Regents Of The University Of Minnesota Triterpenes having antibacterial activity
EP1322661A1 (fr) 2000-09-29 2003-07-02 Regents Of The University Of Minnesota Triterpenes ayant une activite fongicide dirigee contre les levures
US6951847B2 (en) * 2000-09-29 2005-10-04 Regents Of The University Of Minnesota Methods of treating fungal infections using lupeol
US7309696B2 (en) 2000-10-19 2007-12-18 Wake Forest University Compositions and methods for targeting cancer cells
US6642221B1 (en) 2000-11-15 2003-11-04 Parker Hughes Institute Vanadium compounds as anti-proliferative agents
US6958359B1 (en) * 2000-11-15 2005-10-25 Parker Hughes Institute Vanadium compounds as anti-angiogenic agents
US6878388B1 (en) 2000-11-15 2005-04-12 Parker Hughes Institute Vanadium compounds for treating proliferative cell disorders
AU2002249885A1 (en) 2000-11-17 2002-08-12 Adolor Corporation Delta agonist analgesics
US20040034045A1 (en) * 2000-11-29 2004-02-19 Parker Hughes Institute Inhibitors of thrombin induced platelet aggregation
US7261901B2 (en) * 2001-01-31 2007-08-28 University Of Iowa Research Foundation Vaccine and compositions for the prevention and treatment of neisserial infections
WO2002060936A2 (fr) * 2001-01-31 2002-08-08 University Of Iowa Research Foundation Vaccin et compositions permettant de prevenir et de traiter des infections induites par neisseria
US7232829B2 (en) * 2001-04-06 2007-06-19 Regents Of The University Of Minnesota Therapeutic compounds and methods
KR20030041130A (ko) * 2001-05-29 2003-05-23 코닌클리케 필립스 일렉트로닉스 엔.브이. 금속-세라믹 접착
US7601846B2 (en) * 2001-06-26 2009-10-13 The Regents Of The University Of California Compounds having activity as inhibitors of apoptosis
US20030232794A1 (en) * 2001-06-26 2003-12-18 Cottam Howard B. Use of STAT-6 inhibitors as therapeutic agents
EP1430060B1 (fr) * 2001-07-24 2006-09-13 Southern Methodist University Foundation for Research 7-alkylidene-3-substitues-3-cephem-4-carboxylates utilises en tant qu'inhibiteurs de beta-lactamase
US20030171377A1 (en) * 2001-08-29 2003-09-11 Bigge Christopher Franklin Antidiabetic agents
MXPA04001917A (es) * 2001-08-31 2004-06-15 Thomson Licensing Sa Contador de secuencia para una corriente audio-visual.
US20040116350A1 (en) * 2001-09-17 2004-06-17 Paul Wentworth Jr Methods and compositions relating to hydrogen peroxide and superoxide production by antibodies
US20050129680A1 (en) * 2001-09-17 2005-06-16 Paul Wentworth Antimicrobial activity of antibodies
US20040157280A1 (en) * 2001-09-17 2004-08-12 Paul Wentworth Antibody mediated ozone generation
WO2003029264A2 (fr) * 2001-10-01 2003-04-10 University Of Virginia Patent Foundation Analogues de 2-propynyle adenosine presentant une activite agoniste de a2a et compositions en contenant
WO2003031587A2 (fr) * 2001-10-09 2003-04-17 The Regents Of The University Of California Utilisation d'inhibiteurs de stat-6 comme agents therapeutiques
SI1465625T1 (sl) 2001-11-14 2010-06-30 Univ Rutgers Solubilizirani topoizomerazni strupi
EP1478229B1 (fr) * 2001-11-23 2009-03-11 Rutgers, The State University Synthese amelioree de polyanhyrides
US7030141B2 (en) * 2001-11-29 2006-04-18 Christopher Franklin Bigge Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade
AU2003205332A1 (en) * 2002-01-25 2003-09-02 Philip S. Portoghese Selective analgesic agents
US20080152613A1 (en) * 2002-01-31 2008-06-26 Norburn Robert B Method for manufacturing a skin care composition
CA2416305A1 (fr) * 2002-01-31 2003-07-31 Davies, John Rasage, apres-rasage et compositions revitalisantes pour la peau
US20080152722A1 (en) * 2002-01-31 2008-06-26 Norburn Robert B Skin care composition
WO2003087105A1 (fr) * 2002-04-04 2003-10-23 Alamx, L.L.C. INHIBITEURS DE SERINE ET DE METALLO-ss-LACTAMASES
WO2003086408A1 (fr) * 2002-04-10 2003-10-23 University Of Virginia Patent Foundation Utilisation d'agonistes du recepteur d'adenosine a2a dans le traitement de maladies inflammatoires
US20040156799A1 (en) * 2002-06-04 2004-08-12 Zigang Dong Cancer treatment method and compositions
UA79293C2 (en) * 2002-07-03 2007-06-11 Univ Wayne State 4-(7'-halo-2-quino (xa-) linyloxy)phenoxy propionic acid derivatives as antineoplastic agents
EP1572093B1 (fr) * 2002-08-01 2013-04-17 Eisai Inc. Prévention du cancer avec la glutamine
US6989387B2 (en) * 2002-08-09 2006-01-24 Rutgers, The State University Of New Jersey Nitro and amino substituted topoisomerase agents
US7438918B2 (en) * 2002-08-30 2008-10-21 University Of Iowa Research Foundation Lipid A deficient mutants of Neisseria meningitidis
AU2003260821A1 (en) * 2002-09-11 2004-04-30 Warner-Lambert Company Llc Inhibitors of factor xa and other serine proteases involved in the coagulation cascade
US8900607B1 (en) 2002-09-25 2014-12-02 Chemsil Silicones, Inc. Clear, greaseless skin-care compositions
EP1565080B1 (fr) 2002-10-10 2014-01-15 Cornell Research Foundation, Inc. Nouvelles proteines immunogenes de leptospira
WO2004036188A2 (fr) * 2002-10-18 2004-04-29 Cylene Pharmaceuticals, Inc. Procedes servant a identifier des molecules antivirales ciblees vers des structures quadruplex
EP2258392A1 (fr) 2002-11-08 2010-12-08 Ablynx N.V. Procédé d'administration de polypeptides thérapeutiques
EP2267032A3 (fr) 2002-11-08 2011-11-09 Ablynx N.V. Procédé d'administration de polypeptides thérapeutiques et polypeptides correspondants
BR0315628A (pt) * 2002-11-14 2005-08-23 Novartis Ag Geração de ozÈnio mediada por anticorpo ou neutrófilo
US7297340B2 (en) * 2003-01-07 2007-11-20 University Of Iowa Research Foundation Vaccine and method for preventing biofilm formation
US9028816B2 (en) 2003-01-10 2015-05-12 Ablynx N.V. Polypeptides and polypeptide constructs comprising single domain antibodies directed against von Willebrand factor
US20050079512A1 (en) * 2003-02-26 2005-04-14 Emerson Beverly M. Methods of modulating gene expression
US7354916B2 (en) * 2003-04-07 2008-04-08 Cylene Pharmaceuticals Substituted quinobenzoxazine analogs
NZ543006A (en) * 2003-04-07 2009-03-31 Cylene Pharmaceuticals Inc Substituted quinobenzoxazine analogs
US7507727B2 (en) * 2003-04-07 2009-03-24 Cylene Pharmaceuticals, Inc. Substituted quinobenzoxazine analogs and methods of using thereof
WO2004091627A2 (fr) * 2003-04-07 2004-10-28 Cylene Pharmaceuticals, Inc. Analogues heterocycliques de 1,4-dihydro-4-oxo-1,8-naphthpyridine substitues
ATE478663T1 (de) 2003-06-25 2010-09-15 Burnham Inst Analoga von apogossypol zur verwendung in der behandlung von krebs
WO2005003140A1 (fr) * 2003-07-02 2005-01-13 Pharmacia & Upjohn Company Llc 4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides utilises comme agents antiviraux
BRPI0413922B8 (pt) 2003-08-25 2021-05-25 Adenosine Therapeutics Llc xantinas de 8-heteroarila substituída
US9532994B2 (en) 2003-08-29 2017-01-03 The Regents Of The University Of California Agents and methods for enhancing bone formation by oxysterols in combination with bone morphogenic proteins
ATE485307T1 (de) 2003-11-07 2010-11-15 Ablynx Nv Camelidae schwere ketten antikörper vhhs gegen epidermalen wachstumfaktor rezeptor (egfr) und ihre verwendung
US8034548B2 (en) * 2003-12-19 2011-10-11 The Regents Of The University Of California Methods and materials for assessing prostate cancer therapies
US20060003948A1 (en) * 2004-02-06 2006-01-05 Krasutsky Pavel A Compositions that include a triterpene and a carrier
JP4934432B2 (ja) 2004-02-19 2012-05-16 レクサン ファーマシューティカルズ インコーポレイテッド キナゾリン誘導体およびキナゾリン誘導体の治療への使用
US20050187191A1 (en) * 2004-02-20 2005-08-25 Kucera Louis S. Methods and compositions for the treatment of respiratory syncytial virus
US20050187192A1 (en) * 2004-02-20 2005-08-25 Kucera Pharmaceutical Company Phospholipids for the treatment of infection by togaviruses, herpes viruses and coronaviruses
AU2005232526B2 (en) * 2004-02-24 2011-06-23 The Regents Of The University Of California Methods and materials for assessing prostate cancer therapies and compounds
PL2574341T3 (pl) 2004-03-29 2017-09-29 University Of South Florida Efektywne leczenie guzów i raka fosforanem tricyrybiny
US7576069B2 (en) * 2004-08-02 2009-08-18 University Of Virginia Patent Foundation 2-polycyclic propynyl adenosine analogs having A2A agonist activity
EP2266994B1 (fr) 2004-08-02 2013-04-03 University Of Virginia Patent Foundation Analogues de 2-propynyle adenosine comprenant des groupes 5'-ribose modifies presentant une activite agoniste A2A
WO2006026380A2 (fr) * 2004-08-25 2006-03-09 University Of Iowa Research Foundation Inhibiteurs de la geranylgeranyl pyrophosphate synthase
US7718680B2 (en) * 2004-09-23 2010-05-18 Burnham Institute For Medical Research Inhibition of lethal factor protease activity from anthrax toxin
WO2006040153A2 (fr) * 2004-10-13 2006-04-20 Ablynx N.V. Nanocorps™ contre la proteine beta-amyloide et polypeptides les renfermant pour le traitement de maladies degeneratives neurales, telles que la maladie d'alzheimer
US8697674B2 (en) * 2004-12-29 2014-04-15 Naturon, Inc. Xanthurenic acid derivative pharmaceutical compositions and methods related thereto
EP1845778A2 (fr) * 2005-01-10 2007-10-24 University Of Virginia Patent Foundation Synthese d'inhibiteurs de p90rsk
FR2882518B1 (fr) * 2005-02-28 2012-10-19 Oreal Coloration de matieres keratiniques notamment humaines par transfert thermique a sec d'un colorant direct anthraquinonique, composition comprenant ledit colorant et son procede de preparation
US20060230546A1 (en) * 2005-02-28 2006-10-19 Eric Bone Anhydrous composition in the form of a film comprising at least one film-forming polymer and at least one oxidation dye, preparation, and dyeing process
FR2882560B1 (fr) * 2005-02-28 2007-05-18 Oreal Composition anhydre sous forme de film comprenant un polymere filmogene et un colorant d'oxydation, preparation et procede de coloration la mettant en oeuvre
US20060236469A1 (en) * 2005-02-28 2006-10-26 Eric Bone Anhydrous composition in the form of a film comprising a film-forming polymer and oxidizing agent, preparation and process for coloring keratinous fibers employing the anhydrous composition
FR2882521B1 (fr) * 2005-02-28 2008-05-09 Oreal Coloration de matieres keratiniques notamment humaines par transfert thermique a sec d'un colorant direct, composition comprenant ledit colorant et son procede de preparation
US20060242771A1 (en) * 2005-02-28 2006-11-02 Eric Bone Anhydrous composition in the form of a film comprising a film-forming polymer and a direct dye, preparation and dyeing process using the composition
FR2882519B1 (fr) * 2005-02-28 2008-12-26 Oreal Coloration de matieres keratiniques notamment humaines par transfert thermique a sec d'un colorant direct azomethinique composition comprenant ledit colorant et son procede de preparation
FR2882652B1 (fr) * 2005-03-03 2007-06-08 Jacqueline Fellous Composition pharmaceutique et/ou cosmetique, procede de preparation et creme pour les mains
KR20070115939A (ko) * 2005-03-10 2007-12-06 제이알 켐, 엘엘씨 벤조일 퍼옥사이드 조성물 및 이용 방법
US7390431B2 (en) * 2005-03-10 2008-06-24 Jr Chem, Llc Stable organic peroxide compositions
KR102481886B1 (ko) 2005-05-13 2022-12-28 더 리전트 오브 더 유니버시티 오브 캘리포니아 디아릴히단토인 화합물
US7709517B2 (en) 2005-05-13 2010-05-04 The Regents Of The University Of California Diarylhydantoin compounds
HUE045710T2 (hu) 2005-05-18 2020-01-28 Ablynx Nv Javított, alfa tumor nekrózis faktor elleni nanobodies
EP3243839A1 (fr) 2005-05-20 2017-11-15 Ablynx N.V. Nano-corps améliorés pour le traitement des troubles liés à l'agrégation
US7556820B2 (en) 2005-06-29 2009-07-07 Jr Chem, Llc Stable organic peroxide compositions
US20090306023A1 (en) * 2005-06-29 2009-12-10 Ramirez Jose E Stable organic peroxide compositions
US20070001145A1 (en) * 2005-06-29 2007-01-04 Faryniarz Joseph R Stable organic peroxide compositions
WO2007019308A2 (fr) * 2005-08-03 2007-02-15 The Regents Of The University Of California Analogues d'illudine utiles en tant qu'agents anticancereux
WO2007024707A2 (fr) 2005-08-22 2007-03-01 The Regents Of The University Of California Agonistes tlr
US20090291437A1 (en) * 2005-11-02 2009-11-26 O'brien Sean Methods for targeting quadruplex sequences
WO2007120972A2 (fr) * 2006-02-10 2007-10-25 University Of Virginia Patent Foundation Procede permettant de traiter l'anemie a hematies falciformes
WO2007098281A2 (fr) 2006-02-27 2007-08-30 Regents Of The University Of California Composés oxystérols et voie
WO2007111948A2 (fr) * 2006-03-22 2007-10-04 The Regents Of The University Of California Inhibiteurs de prényltransférases protéiques
HUE032085T2 (en) 2006-03-27 2017-09-28 Univ California Androgen receptor modulator for the treatment of prostate cancer and androgen receptor related diseases
JP5350217B2 (ja) * 2006-03-29 2013-11-27 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア ジアリールチオヒダントイン化合物
US8093235B2 (en) 2006-04-25 2012-01-10 Rutgers, The State University Of New Jersey Macrocyclic compounds which stabilize G-Quadruplex DNA and RNA
US8426568B2 (en) * 2006-05-22 2013-04-23 University Of Virginia Patent Foundation Rhamnose substituents of SL0101 and therapeutic uses thereof
WO2007146831A2 (fr) * 2006-06-08 2007-12-21 Cylene Pharmaceuticals, Inc. Analogues de quinolone dérivés avec de l'acide sulfonique, du sulfonate ou du sulfonamide
US20110112086A1 (en) * 2006-06-08 2011-05-12 Cylene Pharmaceuticals, Inc. Pyridinone analogs
US8188063B2 (en) * 2006-06-19 2012-05-29 University Of Virginia Patent Foundation Use of adenosine A2A modulators to treat spinal cord injury
US8034829B2 (en) 2006-11-17 2011-10-11 Rexahn Pharmaceuticals, Inc. 5, 6, or 7-substituted-3-(hetero)arylisoquinolinamine derivatives and therapeutic use thereof
CA2670595A1 (fr) * 2006-11-29 2008-06-05 Pfizer Products Inc. 1- [ ( 4 -chlorophenyl) amide 5-{[2-fluoro-4- (2-oxo-2h-pyridin-1-yl) -phenyl]amide) d'acide (r) -5-methyl-4, 5-dihydro- pyrazole-1, 5-dicarboxylique servant d'inhibiteur du facteur xa
WO2008074839A2 (fr) 2006-12-19 2008-06-26 Ablynx N.V. Séquences d'acides aminés dirigées contre les gpcr et polypeptides les contenant pour le traitement de maladies et de troubles liés au gpcr
EP2102244A2 (fr) 2006-12-19 2009-09-23 Ablynx N.V. Séquences d'acides aminés dirigées contre une métalloprotéinase de la famille adam et polypeptides les comprenant à des fins de traitement de maladies et troubles liés à adam
JP2010518108A (ja) 2007-02-06 2010-05-27 ユニバーシティ オブ ルーイビル リサーチ ファウンデーション,インコーポレーテッド 治療化合物
BRPI0807196A2 (pt) 2007-02-07 2014-06-03 Univ California Método para prevenir ou inibir uma infecção bacteriana, vacina, composto, e, método para prevenir, tratar ou inibir a asma
WO2008103818A1 (fr) * 2007-02-21 2008-08-28 University Of Louisville Research Foundation Compositions thérapeutiques à base de cotinine
US8569449B2 (en) 2007-05-08 2013-10-29 University Of Louisville Research Foundation, Inc. Synthetic peptides and peptide mimetics
BRPI0815563A2 (pt) * 2007-07-12 2015-02-18 Univ South Florida Inibidores de akt/pkb com atividade antitumoral
EP2185568A4 (fr) 2007-08-02 2010-08-11 Trustees Rutgers The State Uni Composés thérapeutiques
PT3092901T (pt) * 2007-10-05 2020-05-21 Senhwa Biosciences Inc Análogos de quinolona e respetivos métodos relacionados
EP2205088B1 (fr) 2007-10-19 2018-02-21 Burnham Institute for Medical Research Inhibiteurs à base de naphtalène de protéines anti-apoptotiques
WO2009055677A1 (fr) * 2007-10-24 2009-04-30 University Of South Florida Disulfures s-hétérosubstitués antibactériens
TW201716385A (zh) 2007-10-26 2017-05-16 加州大學董事會 二芳基乙內醯脲類化合物
EP2231164A1 (fr) 2007-12-03 2010-09-29 The Regents of the University of California Oxystérols pour l'activation du signal hedgehog, de l'ostéoinduction, de l'anti-adipogenèse et du signal wnt
US8058259B2 (en) * 2007-12-20 2011-11-15 University Of Virginia Patent Foundation Substituted 4-{3-[6-amino-9-(3,4-dihydroxy-tetrahydro-furan-2-yl)-9H-purin-2-yl]-prop-2-ynyl}-piperidine-1-carboxylic acid esters as A2AR agonists
WO2009108716A2 (fr) 2008-02-27 2009-09-03 University Of Louisville Research Foundation Peptides synthétiques
WO2009114539A2 (fr) * 2008-03-10 2009-09-17 University Of Louisville Research Foundation Traitements neuroprotecteurs à base de peptide de liaison de l'intégrine et de l'angiopoïétine-1
US20110046101A1 (en) * 2008-03-17 2011-02-24 Dmitrienko Gary I Bate-lactamase inhibitors
WO2009146112A1 (fr) * 2008-04-02 2009-12-03 University Of Virginia Patent Foundation Compositions et procédés pour inhiber la sphingosine kinase
EP2947097A1 (fr) 2008-04-07 2015-11-25 Ablynx N.V. Séquences d'acides aminés dirigées contre les voies Notch et leurs utilisations
CA2721203C (fr) 2008-04-16 2016-11-01 Howard University Inhibiteurs de proteine phosphatase-1 et leurs utilisations
US9212226B2 (en) 2008-05-16 2015-12-15 Ablynx N.V. Amino acid sequences directed against CXCR4 and other GPCRs and compounds comprising the same
US9872867B2 (en) * 2008-06-06 2018-01-23 Tanya Kuritz Methods and compositions for modulation of innate immunity
WO2010005534A2 (fr) * 2008-06-30 2010-01-14 H. Lee Moffitt Cancer Center And Research Institute, Inc. Inhibiteurs des protéasomes pour l’induction sélective de l’apoptose dans les cellules cancéreuses
US7947717B2 (en) * 2008-07-18 2011-05-24 Burnham Institute For Medical Research Inhibitors of lethal factor protease
WO2010011666A2 (fr) * 2008-07-21 2010-01-28 University Of South Florida Inhibiteurs de shp-2 à squelette indoline et procédé de traitement du cancer
US9125821B2 (en) 2008-07-28 2015-09-08 The Regents Of The University Of California Nanodrug targeting protein geranylgeranylation
WO2010014054A1 (fr) 2008-07-28 2010-02-04 The Regents Of The University Of California Inhibiteurs de prényltransférases de protéine
US20110142795A1 (en) 2008-08-05 2011-06-16 University Of South Florida Methods of treating cognitive impairment
US9132168B2 (en) 2008-08-05 2015-09-15 University Of South Florida Methods of treating cognitive impairment
AU2009279400A1 (en) * 2008-08-08 2010-02-11 University Of Florida Research Foundation, Inc. Lipid compounds for supression of tumorigenesis
TW201038578A (en) 2009-01-30 2010-11-01 Univ Rutgers Methods to treat cancer
CA2755975A1 (fr) 2009-03-20 2010-09-23 University Of Iowa Research Foundation Bisphosphonates prenyles en tant qu'agents antituberculeux
RU2539798C2 (ru) 2009-04-10 2015-01-27 Аблинкс Нв Улучшенные аминокислотные последовательности против il-6r и содержащие их полипептиды для лечения связанных с il-6r заболеваний и нарушений
US8487131B2 (en) 2009-04-15 2013-07-16 Sanford-Burnham Medical Research Institute Optically pure apogossypol derivative as pan-active inhibitor of anti-apoptotic B-cell lymphoma/leukemia-2 (BCL-2)
MX2011010872A (es) 2009-04-15 2012-01-19 Sanford Burnham Med Res Inst Inhibidores basados en naftaleno de proteinas anti-apoptoticas.
EP2430016B1 (fr) 2009-05-13 2020-04-01 University Of Virginia Patent Foundation Inhibiteurs de leucémie inv(16)
US8263762B2 (en) 2009-06-30 2012-09-11 Dogwood Pharmaceuticals, Inc. Alkoxy-carbonyl-amino-alkynyl-adenosine compounds and derivatives thereof as A2AR agonists
WO2011005871A1 (fr) 2009-07-07 2011-01-13 Pgxhealth, Llc 8-[6-carbonylamino-3-pyridyle] xanthines substituées en tant qu’antagonistes de l’adénosine a2b
AU2010278730A1 (en) 2009-07-31 2012-03-01 Biocryst Pharmaceuticals, Inc. Pyrrolo [1, 2-b] pyridazine derivatives as janus kinase inhibitors
US9040673B2 (en) 2009-08-14 2015-05-26 University Of Virginia Patent Foundation Synthesis and identification of novel RSK-specific inhibitors
TW201111385A (en) 2009-08-27 2011-04-01 Biocryst Pharm Inc Heterocyclic compounds as janus kinase inhibitors
US8642088B2 (en) 2009-09-04 2014-02-04 Wisconsin Alumni Research Foundation Tannin-chitosan composites
US8937193B2 (en) * 2009-10-08 2015-01-20 Sanford-Burnham Medical Research Institute Apogossypolone derivatives as anticancer agents
US8796300B2 (en) 2009-11-05 2014-08-05 Rutgers, The State University Of New Jersey Therapeutic compounds
CN102892755A (zh) 2009-12-23 2013-01-23 韦恩州立大学 治疗性化合物
WO2011079230A2 (fr) 2009-12-23 2011-06-30 Biocryst Pharmaceuticals, Inc. Composés hétérocycliques comme inhibiteurs de la janus kinase
EP3124481B1 (fr) 2010-02-16 2018-03-28 Aragon Pharmaceuticals, Inc. Modulateurs de récepteur d'androgène et utilisations associées
WO2011103686A1 (fr) 2010-02-26 2011-09-01 Viswanatha , Sundaramma Dérivés de la céphalosporine utiles comme inhibiteurs de la β-lactamase et leurs compositions et procédés d'utilisation
EP2552885A1 (fr) 2010-04-02 2013-02-06 TSRL, Inc. Inhibiteurs de la neuraminidase
US9221808B2 (en) 2010-04-16 2015-12-29 H. Lee Moffitt Cancer Center And Research Institute, Inc. Pyridylthiazole-based ureas as inhibitors of Rho associated protein kinase (ROCK) and methods of use
WO2011133696A2 (fr) 2010-04-20 2011-10-27 Regents Of The University Of Minnesota Méthodes de lutte contre l'athérosclérose
MX2012013824A (es) 2010-05-28 2013-03-12 Biocryst Pharm Inc Compuestos heterociclicos como inhibidores de cinasa janus.
WO2012027494A1 (fr) 2010-08-24 2012-03-01 Regents Of The University Of Minnesota Réactifs bispécifiques de ciblage
US8609672B2 (en) 2010-08-27 2013-12-17 University Of The Pacific Piperazinylpyrimidine analogues as protein kinase inhibitors
AU2011323784A1 (en) 2010-10-25 2013-05-30 Regents Of The University Of Minnesota Therapeutic composition for treatment of glioblastoma
EP3150590B1 (fr) 2011-02-07 2019-10-16 Biogen MA Inc. Agents de modulation s1p
EP2683837A2 (fr) 2011-03-07 2014-01-15 University Of Louisville Research Foundation, Inc. Marqueur prédictif de l'efficacité thérapeutique de l'inhibiteur dnmt1, et procédés d'utilisation dudit marqueur
WO2012135697A2 (fr) 2011-03-30 2012-10-04 H. Lee Moffitt Cancer Center & Research Institute Inc. Nouveaux inhibiteurs de la rho-kinase et leurs procédés d'utilisation
US10059746B2 (en) 2011-04-04 2018-08-28 University Of Iowa Research Foundation Methods of improving vaccine immunogenicity
WO2012139015A1 (fr) 2011-04-06 2012-10-11 Rutgers, The State University Of New Jersey Polymères et procédés pour le traitement de la douleur
US20120270860A1 (en) 2011-04-19 2012-10-25 Gihyun Yoon Methods for treating or preventing alcohol-related disorders or craving-related disorders
WO2012145678A1 (fr) 2011-04-20 2012-10-26 Regents Of The University Of Minnesota Composés parthénolides anticancéreux et anti-inflammatoire
WO2012177770A1 (fr) 2011-06-20 2012-12-27 Rutgers, The State University Of New Jersey Inhibiteurs bipartites de l'arn polymérase bactérienne
EP2729483A1 (fr) 2011-07-08 2014-05-14 Regents Of The University Of Minnesota Analogues du glutathion et leurs utilisations
WO2013016206A1 (fr) 2011-07-22 2013-01-31 University Of Louisville Research Foundation, Inc. Composés anti-biofilm
BR112014002200A2 (pt) 2011-07-29 2017-03-07 Medivation Prostate Therapeutics Inc tratamento de câncer de mama
WO2013028866A1 (fr) 2011-08-24 2013-02-28 Regents Of The University Of Minnesota Composés et méthodes thérapeutiques
EP2750508A4 (fr) 2011-08-30 2015-01-14 Univ Wayne State Composés et procédés thérapeutiques
WO2013033345A1 (fr) 2011-08-30 2013-03-07 Regents Of The University Of Minnesota Immunomodulateurs et conjugués d'immunomodulateurs
EP2763658B1 (fr) 2011-09-08 2021-06-23 Western University Of Health Sciences Liposomes ciblés en thérapie cancéreuse
US9573906B2 (en) 2011-09-15 2017-02-21 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona Acting For And On Behalf Of Arizona State University Therapeutic compounds
US9828326B2 (en) * 2011-12-27 2017-11-28 Northeast Ohio Medical University Amooranin compounds and analogs thereof and related methods of use
US9517994B2 (en) 2012-01-05 2016-12-13 Rutgers, The State University Of New Jersey Antibacterial agents: phloroglucinol derivatives
EP2802602B1 (fr) 2012-01-11 2019-03-27 Arizona Board of Regents, a Body Corporate of the State of Arizona acting for and on behalf of Arizona State University Fragments des anticorps bispecifiques pour des proteines de maladies neurologiques et procedes d'utilisation
US8947424B2 (en) 2012-01-17 2015-02-03 Eastman Kodak Company Spectral stereoscopic projection system
EP2804606B1 (fr) 2012-01-19 2017-06-28 Hybrid Medical, LLC Préparations thérapeutiques topiques
WO2013109972A2 (fr) 2012-01-20 2013-07-25 Regents Of The University Of Minnesota Composés thérapeutiques
US20130195752A1 (en) 2012-02-01 2013-08-01 Regents Of The University Of Minnesota Functionalized nanoparticles and methods of use thereof
CA2863427C (fr) 2012-02-01 2022-07-12 The Governors Of The University Of Alberta Utilisation de pdgfr-alpha en tant que marqueur de diagnostic pour le cancer de la thyroide papillaire
WO2013119564A1 (fr) 2012-02-06 2013-08-15 Rutgers, The State University Of New Jersey Agents antibactériens : combinaison d'une rifamycine et d'un inhibiteur de région de transition
WO2013119946A1 (fr) 2012-02-08 2013-08-15 Of Virginia Patent Foundation University Inhibiteurs de la kinase sphingosine avec base à longue chaîne
US9187446B2 (en) 2012-03-22 2015-11-17 Rutgers, The State University Of New Jersey Antibacterial agents: sidechainfluorinated myxopyronin derivatives
ES2655027T3 (es) 2012-03-26 2018-02-16 University Of Iowa Research Foundation Análogos de schweinfurthinas
US9340501B2 (en) 2012-04-16 2016-05-17 H. Lee Moffitt Cancer Center And Research Institute, Inc. Marinopyrrole derivatives as anticancer agents
US9272016B2 (en) 2012-04-20 2016-03-01 University Of Iowa Research Foundation Methods to enhance RNAi oligonucleotide delivery to respiratory epithelial cells
CN104395331B (zh) 2012-05-07 2016-11-02 加利福尼亚大学董事会 诱导骨生成和hedgehog 信号传导且抑制脂肪形成的氧固醇类似物氧固醇化合物133
EP2861570B1 (fr) 2012-06-19 2018-07-18 Rutgers, The State University of New Jersey Agents antibactériens : dérivés aryliques de la myxopyronine
WO2013192388A1 (fr) 2012-06-20 2013-12-27 University Of Virginia Patent Foundation Compositions et procédés pour réguler l'homéostasie du glucose et l'action de l'insuline
US9669115B2 (en) 2012-06-29 2017-06-06 University Of Iowa Research Foundation Co-crystals and salts of contrast agents and imaging
ES2617448T3 (es) 2012-07-05 2017-06-19 University Of Iowa Research Foundation Bisfosfonatos terapéuticos
RU2696278C2 (ru) 2012-07-18 2019-08-01 Юниверсити Оф Нотр Дам Дю Лак 5,5-гетероароматические противоинфекционные соединения
WO2014018671A1 (fr) 2012-07-24 2014-01-30 Regents Of The University Of Minnesota Composés thérapeutiques pour le traitement du cancer
US9522889B2 (en) 2012-07-27 2016-12-20 Biogen Ma Inc. ATX modulating agents
KR20150036767A (ko) 2012-08-01 2015-04-07 루이스 앤드 클라크 파마슈티컬스, 인코포레이티드 A2a 효능제로서의 n-알킬 2-(이치환된)알키닐아데노신-5-유론아미드
US9249116B2 (en) 2012-08-03 2016-02-02 The Board Of Trustees Of The University Of Illinois Enzyme-activating compounds and compositions
WO2014025709A1 (fr) 2012-08-06 2014-02-13 Biogen Idec Ma Inc. Composés étant des agents de modulation de s1p et/ou des agents de modulation d'atx
WO2014025708A1 (fr) 2012-08-06 2014-02-13 Biogen Idec Ma Inc. Composés étant des agents de modulation de s1p et/ou des agents de modulation d'atx
WO2014031732A2 (fr) 2012-08-22 2014-02-27 Cornell University Méthodes d'inhibition de la fascine
WO2014039860A2 (fr) 2012-09-07 2014-03-13 University Of Louisville Research Foundation, Inc. Compositions et méthodes de modulation de l'activité inhibitrice de la dnmt1
US9573938B2 (en) 2012-09-11 2017-02-21 Rutgers, The State University Of New Jersey Therapeutic hydroxypyridinones, hydroxypyrimidinones and hydroxypyridazinones
SI3305285T1 (sl) 2012-09-26 2021-03-31 Aragon Pharmaceuticals, Inc. Anti-androgeni za zdravljenje proti kastraciji odpornega ne-metastatskega raka
US9957214B2 (en) 2012-10-10 2018-05-01 Arizona Board Of Regents On Behalf Of Arizona State University Multifunctional radical quenchers
US9364406B2 (en) 2012-10-12 2016-06-14 Regents Of The University Of Minnesota Open chained or fused 1,1′-alkylene-bis-uracil derivatives, useful in skin UV-protection
WO2014066840A1 (fr) 2012-10-26 2014-05-01 Regents Of The University Of Minnesota Inhibiteurs d'aurora kinase
US10519161B2 (en) 2012-10-29 2019-12-31 Southern Methodist University Methods of generating beta-lactamase resistant carbapenem compounds
US9701638B2 (en) 2012-11-09 2017-07-11 Rutgers, The State University Of New Jersey Therapeutic hydroxyquinolones
WO2014078778A2 (fr) 2012-11-16 2014-05-22 Biocryst Pharmaceuticals, Inc. Nucléosides antiviraux contenant de l'azasucre
US9670199B2 (en) 2012-11-19 2017-06-06 Regents Of The University Of Minnesota Ergoline derivatives as dopamine receptor modulators
US9850206B2 (en) 2012-11-20 2017-12-26 Biogen Ma Inc. S1P and/or ATX modulating agents
WO2014081756A1 (fr) 2012-11-20 2014-05-30 Biogen Idec Ma Inc. Agents de modulation de s1p et/ou atx
JOP20200097A1 (ar) 2013-01-15 2017-06-16 Aragon Pharmaceuticals Inc معدل مستقبل أندروجين واستخداماته
US9700044B2 (en) 2013-01-22 2017-07-11 H. Lee Moffitt Cancer Center And Research Institute, Inc. Symmetrical marinopyrrole derivatives as potential antibiotic agents
US9765016B2 (en) 2013-01-29 2017-09-19 Biogen Ma Inc. S1P modulating agents
WO2014124317A1 (fr) 2013-02-08 2014-08-14 Regents Of The University Of Minnesota Conjugués analgésiques
JP2016510749A (ja) 2013-03-05 2016-04-11 ユニヴァーシティー オブ ノートル ダム デュ ラック キナゾリノン抗生物質
WO2014158685A2 (fr) * 2013-03-14 2014-10-02 Avon Products, Inc Extraits de tetracera asiatica et procédés d'utilisation
US9387250B2 (en) 2013-03-15 2016-07-12 Rutgers, The State University Of New Jersey Therapeutic compositions for bone repair
EP2968263A2 (fr) 2013-03-15 2016-01-20 Genentech, Inc. Traitement de maladies th2 par inhibition des protéines brd7 et brd9 contenant un bromodomaine
WO2014143672A1 (fr) 2013-03-15 2014-09-18 Biogen Idec Ma Inc. Composés macrocycliques en tant qu'inhibiteurs de irak4 pour le traitement de maladies inflammatoires
US20160039825A1 (en) 2013-03-15 2016-02-11 Biogen Ma Inc. S1p and/or atx modulating agents
WO2014179756A1 (fr) 2013-05-02 2014-11-06 The Regents Of The University Of California Agents de ciblage osseux à base d'oxystérol ostéogène à sélectivité osseuse
US9862672B2 (en) 2013-05-29 2018-01-09 Rutgers, The State University Of New Jersey Antioxidant-based poly(anhydride-esters)
WO2015003095A1 (fr) 2013-07-03 2015-01-08 Regents Of The University Of Minnesota Composés et compositions de bronzage sans soleil
WO2015021149A1 (fr) 2013-08-06 2015-02-12 H. Lee Moffitt Cancer Center And Research Institute, Inc. Inhibiteurs de la tyrosine kinase ack1/tnk2
CN106102758B (zh) 2013-11-11 2020-09-22 夸利蒂赫布丘蒂克斯公司 卡瓦衍生的治疗性化合物及其使用方法
US9339482B2 (en) 2013-11-22 2016-05-17 Regents Of The University Of Minnesota Methods to treat dysregulated blood glucose disorders
US9315523B2 (en) 2013-12-06 2016-04-19 Rutgers, The State University Of New Jersey Cyclic dinucleosides
EP3102193B1 (fr) 2014-02-06 2023-01-11 Rutgers, The State University of New Jersey Agents antibactériens : n(alpha)-aroyl-n-aryl-phénylalaninamides
WO2015127125A1 (fr) 2014-02-20 2015-08-27 Cornell University Composés et procédés d'inhibition de la fascine
WO2015130805A1 (fr) 2014-02-26 2015-09-03 Arizona Board Of Regents On Behalf Of Arizona State University Compositions de grille d'adn et procédés
US10272055B2 (en) 2014-03-06 2019-04-30 Regents Of The University Of Minnesota Therapeutic compounds and methods
RS61159B1 (sr) 2014-03-07 2021-01-29 Biocryst Pharm Inc Pirazoli supstituisani trifluorometilom kao inhibitori humanog kalikreina plazme
US10197575B2 (en) 2014-03-31 2019-02-05 H. Lee Moffitt Cancer Center And Research Institute, Inc. Stabilized peptoid-peptide hybrids and uses thereof
CA2946112C (fr) 2014-04-18 2020-11-24 The Governors Of The University Of Alberta Therapie ciblee pour restaurer le transport de l'iode radioactif pour traiter le cancer de la thyroide
US9556113B2 (en) 2014-04-29 2017-01-31 The South Dakota Board Of Regents Combination uses of dichloroacetate and oxamate, and their prodrugs, for cancer treatment
CA2945404A1 (fr) 2014-05-02 2015-11-05 The Regents Of The University Of California Analogues de bisphosphonates d'oxysterol osteogeniques ciblant specifiquement l'os
US9987299B2 (en) 2014-05-05 2018-06-05 University Of Iowa Research Foundation Methods of improving RNAi in well-differentiated airway epithelia
TW201613917A (en) 2014-06-06 2016-04-16 Biogen Ma Inc ATX modulating agents
US10138203B2 (en) 2014-06-16 2018-11-27 Rutgers, The State University Of New Jersey Antibacterial agents
US9737598B2 (en) 2014-06-30 2017-08-22 Regents Of The University Of Minnesota CD200 inhibitors and methods of use thereof
AU2015304860B2 (en) 2014-08-19 2020-07-16 Hsiri Therapeutics, LLC Antibacterial sideromycins
US11135178B2 (en) 2014-09-11 2021-10-05 University Of Iowa Research Foundation Thymol and carvacol for use in medicine
WO2016076929A1 (fr) 2014-11-13 2016-05-19 University Of Iowa Research Foundation Procédés pour générer des cellules épithéliales
DK3258938T3 (da) 2015-02-17 2021-02-01 Univ Arizona State Phenothiazinanaloger som mitokondrie terapeutiske midler
US10364227B2 (en) 2015-02-17 2019-07-30 Arizona Board Of Regents On Behalf Of Arizona State University Therapeutic compounds
WO2016172187A1 (fr) 2015-04-20 2016-10-27 H. Lee Moffitt Cancer Center And Research Institute, Inc. Méthodes et compositions associées à des inhibiteurs de kras
JP6959142B2 (ja) 2015-05-06 2021-11-02 エイチ リー モフィット キャンサー センター アンド リサーチ インスティテュート インコーポレイテッド Mc1rを標的とする放射線療法用作用物質およびコンパニオンイメージング作用物質
CN108026084A (zh) 2015-05-07 2018-05-11 夸利蒂赫布丘蒂克斯公司 治疗化合物及其使用方法
CA2986423C (fr) 2015-05-18 2022-05-10 The Arizona Board Of Regents On Behalf Of The University Of Arizona Amelioration de la prevention du cancer par de nouvelles melanotrines
US11369569B2 (en) 2015-06-15 2022-06-28 University Of Virginia Patent Foundation Target-specific delivery of therapeutic agents
US10308663B2 (en) 2015-06-16 2019-06-04 University Of Virginia Patent Foundation Inhibitors of PTP4A3 for the treatment of cancer
WO2017011686A1 (fr) 2015-07-14 2017-01-19 University Of Iowa Research Foundation Promédicaments fluorescents
EP3328372A4 (fr) 2015-07-28 2019-03-20 University Of Iowa Research Foundation Compositions et méthodes de traitement du cancer
EP3328496A4 (fr) 2015-08-02 2018-12-19 H. Lee Moffitt Cancer Center And Research Institute, Inc. Inhibiteurs de la tyrosine kinase ack1/tnk2
US10550124B2 (en) 2015-08-13 2020-02-04 San Diego State University Foundation Atropisomerism for increased kinase inhibitor selectivity
JP6639651B2 (ja) 2015-09-04 2020-02-05 ヤンセン ファーマシューティカ エヌ.ベー. 疼痛のための治療化合物及びその合成
FI4019022T3 (fi) 2015-10-01 2024-04-19 Biocryst Pharm Inc Ihmisen plasman kallikreiinin estäjiä
EP3355938B1 (fr) 2015-10-01 2024-02-07 Goleini Inc. Expression ciblée de canaux chlorure et procédés d'utilisation de celle-ci
US10738016B2 (en) 2015-10-13 2020-08-11 H. Lee Moffitt Cancer Center And Research Institute, Inc. BRD4-kinase inhibitors as cancer therapeutics
EP3370763B1 (fr) 2015-11-03 2024-04-10 Regents of the University of Minnesota Inhibiteurs de cd200 et leurs méthodes d'utilisation
KR20180113976A (ko) 2015-11-20 2018-10-17 센화 바이오사이언시즈 인코포레이티드 암을 치료하기 위한 테트라사이클릭 퀴놀론 유사체의 병행 요법
US9957282B2 (en) 2015-12-14 2018-05-01 Senhwa Biosciences, Inc. Crystalline forms of quinolone analogs and their salts
US9980951B2 (en) 2015-12-17 2018-05-29 University Of Iowa Research Foundation Image guided therapy for cancer
TWI726969B (zh) 2016-01-11 2021-05-11 比利時商健生藥品公司 用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物
TWI747873B (zh) 2016-02-01 2021-12-01 美商百歐克斯製藥公司 苯并吡唑化合物及其類似物
WO2017156527A1 (fr) 2016-03-11 2017-09-14 H. Lee Moffitt Cancer Center And Research Institute, Inc. Inhibiteurs des kinases aurora et des janus kinases pour la prévention de la maladie du greffon contre l'hôte
US11395820B2 (en) 2016-03-16 2022-07-26 H. Lee Moffitt Cancer Center And Research Institute, Inc. Small molecules against cereblon to enhance effector t cell function
US11529340B2 (en) 2016-03-22 2022-12-20 Regents Of The University Of Minnesota Combination for treating pain
US10759740B2 (en) 2016-03-24 2020-09-01 Rutgers, The State University Of New Jersey Antibacterial agents
CA3019945A1 (fr) 2016-04-04 2017-10-12 Rutgers, The State University Of New Jersey Poisons de topoisomerase
US10551384B2 (en) 2016-04-07 2020-02-04 Rutgers, The State University Of New Jersey MTOR kinase mutations and methods of use thereof
US20200237840A1 (en) 2016-04-18 2020-07-30 Kenneth Michael MORROW Isolation of plant extracts
EP3452110A4 (fr) 2016-05-04 2019-12-25 H. Lee Moffitt Cancer Center And Research Institute, Inc. Agent ciblé sur un récepteur opioïde de type delta pour l'imagerie moléculaire et l'immunothérapie du cancer
US10899793B2 (en) 2016-05-27 2021-01-26 Regents Of The University Of Minnesota Melanocortin ligands and methods of use thereof
JP2019526617A (ja) 2016-06-20 2019-09-19 ラトガース ザ ステイト ユニバーシティー オブ ニュージャージー 治療用化合物
AU2017281940B2 (en) 2016-06-24 2024-07-11 University Of Iowa Research Foundation Compositions and methods of treating melanoma
EP3490552B1 (fr) 2016-07-26 2022-11-23 University of Southern California Inhibition sélective de bromodomaine de bdf1 fongique
WO2018039077A1 (fr) 2016-08-25 2018-03-01 Arizona Board Of Regents On Behalf Of Arizona State University Composés thérapeutiques
EP3526205A4 (fr) 2016-10-17 2020-05-27 Genentech, Inc. Composés thérapeutiques et leurs procédés d'utilisation
US11124541B2 (en) 2016-10-18 2021-09-21 Regents Of The University Of Minnesota Chimeric melanocortin ligands and methods of use thereof
EP3532057B1 (fr) 2016-10-31 2022-12-21 Biocryst Pharmaceuticals, Inc. Promédicaments d'inhibiteurs de la kallicréine
AU2017367092B2 (en) 2016-11-29 2022-11-03 University Of Iowa Research Foundation Use of NAD precursors for improving maternal health and/or offspring health
US11071747B2 (en) 2016-11-29 2021-07-27 University Of Iowa Research Foundation Use of NAD precursors for breast enhancement
US10710957B2 (en) 2017-01-09 2020-07-14 University Of Central Florida Research Foundation, Inc. Motuporamine derivatives as antimicrobial agents and antibiotic enhancers against resistant gram-negative bacteria
CN110325508B (zh) 2017-01-20 2023-06-30 加利福尼亚大学董事会 雄激素受体的n-末端结构域的抑制剂
US10231947B2 (en) 2017-01-23 2019-03-19 Arizona Board Of Regents On Behalf Of Arizona State University Isochroman compounds and methods of use thereof
US10238626B2 (en) 2017-01-23 2019-03-26 Arizona Board Of Regents On Behalf Of Arizona State University Therapeutic compounds
US10238655B2 (en) 2017-01-23 2019-03-26 Arizona Board Of Regents On Behalf Of Arizona State University Dihydroindene and tetrahydronaphthalene compounds
US11090289B2 (en) 2017-01-24 2021-08-17 University Of Virginia Patent Foundation Compositions and methods for blocking sodium channels
US10294264B2 (en) 2017-04-21 2019-05-21 Warsaw Orthopedic, Inc. Oxysterol-therapeutic agent derivative for bone healing
CA3063174A1 (fr) 2017-05-12 2018-11-15 Innovus Pharmaceuticals, Inc. Methodes therapeutiques et compositions associees
US10434106B2 (en) 2017-05-19 2019-10-08 Warsaw Orthopedic, Inc. Oxysterol-statin compounds for bone growth
US11896591B2 (en) 2017-05-22 2024-02-13 University Of Virginia Patent Foundation Compositions and methods for preparing and using mitochondrial uncouplers
AR112027A1 (es) 2017-06-15 2019-09-11 Biocryst Pharm Inc Inhibidores de alk 2 quinasa que contienen imidazol
ES2968421T3 (es) 2017-06-23 2024-05-09 San Diego State Univ Research Foundation Atropisomerismo para la selectividad potenciada de inhibidor de cinasa
WO2019046467A1 (fr) 2017-08-29 2019-03-07 Rutgers, The State University Of New Jersey Indazoles thérapeutiques
US11254941B2 (en) 2017-08-30 2022-02-22 Arizona Board Of Regents On Behalf Of Arizona State University RNA nanostructures and methods of making and using RNA nanostructures
JP2020536891A (ja) 2017-10-06 2020-12-17 ブルー セラピューティクス,インコーポレイティド 急性又は慢性疼痛を治療する方法
JOP20200076A1 (ar) 2017-10-16 2020-04-30 Aragon Pharmaceuticals Inc مضادات أندروجين لعلاج سرطان البروستاتا غير النقيلي المقاوم للاستئصال
US12037416B2 (en) 2017-11-17 2024-07-16 Cytogel Pharma, Llc Polymer agonists of mu opioid receptors
CA3082575A1 (fr) 2017-11-17 2019-05-23 The Board Of Trustees Of The University Of Illinois Traitement du cancer par degradation de la signalisation double de mek
ES2969958T3 (es) 2017-11-30 2024-05-23 Cytogel Pharma Llc Formulaciones farmacéuticas analgésicas novedosas y usos de las mismas
US11242533B2 (en) 2018-01-10 2022-02-08 Arizona Board Of Regents On Behalf Of Arizona State University RNA-nanostructured double robots and methods of use thereof
US10738093B2 (en) 2018-01-25 2020-08-11 The Hong Kong University Of Science And Technology Discovery of cationic nonribosomal peptides as Gram-negative antibiotics through global genome mining
WO2019160873A1 (fr) 2018-02-13 2019-08-22 Rutgers, The State University Of New Jersey Agents antibactériens : pyronines o-alkyl-deutérés
US20190374550A1 (en) 2018-02-15 2019-12-12 Senhwa Biosciences, Inc. Quinolone analogs and their salts, compositions, and method for their use
WO2019168921A1 (fr) 2018-02-27 2019-09-06 University Of Virginia Patent Foundation Inhibiteur de liposomes/parp ciblés par plectine dans le traitement du cancer
US11572337B2 (en) 2018-03-06 2023-02-07 Rutgers, The State University Of New Jersey Antibacterial agents: arylalkylcarboxamido phloroglucinols
TW202010742A (zh) 2018-04-06 2020-03-16 美商百歐克斯製藥公司 取代的苯并呋喃、苯并吡咯、苯并噻吩及結構相關的補體抑制劑
US20210253538A1 (en) 2018-04-20 2021-08-19 Virginia Tech Intellectual Properties, Inc. Aminopyrazines and related compounds useful as mitochondrial uncouplers
WO2020036654A2 (fr) 2018-04-27 2020-02-20 Arizona Board Of Regents On Behalf Of Arizona State University Topologies moléculaires hautement nouées à partir d'acides nucléiques monocaténaires
US10758594B2 (en) 2018-06-26 2020-09-01 Marine Essence Biosciences Corporation of USA Biomaterial devices and topical compositions for treatment of skin abnormalities
US10912822B2 (en) 2018-06-26 2021-02-09 Marine Essence Biosciences Corporation of USA Biomaterial devices and topical compositions for guided tissue regeneration
PE20210184A1 (es) 2018-07-11 2021-02-02 H Lee Moffitt Cancer Ct & Res Compuestos inmunomoduladores dimericos contra mecanismos basados en cereblon
US10898460B1 (en) 2018-07-20 2021-01-26 University Of South Florida Leishmania inhibitors
US11987568B2 (en) 2018-08-03 2024-05-21 H. Lee Moffitt Cancer Center And Research Institute, Inc. Allosteric inhibitor of WEE1 kinase
US11332499B2 (en) 2018-08-16 2022-05-17 Regents Of The University Of Minnesota Cyclic peptides and methods of use thereof
WO2020106454A2 (fr) 2018-11-07 2020-05-28 Regents Of The University Of Minnesota Compositions analgésiques et anti-accoutumance pour le traitement de la douleur chronique et de la dépendance aux opioïdes
EP3887401A2 (fr) 2018-11-26 2021-10-06 Denali Therapeutics Inc. Procédés de traitement du métabolisme lipidique dérégulé
AU2020208192A1 (en) 2019-01-14 2021-08-05 Regents Of The University Of Minnesota CD200AR ligands for cancer immunotherapy
US10889601B2 (en) 2019-02-11 2021-01-12 University Of Iowa Research Foundation Separations using boron containing hydrocarbon sponges
WO2020225779A1 (fr) 2019-05-09 2020-11-12 Istituto Pasteur Italia - Fondazione Cenci Bolognetti Agonistes de rig-i pour le traitement du cancer et l'immunothérapie
WO2020263989A1 (fr) 2019-06-24 2020-12-30 University Of Iowa Research Foundation Inhibiteurs de jnk en tant qu'agents anticancéreux
US11840703B2 (en) 2019-07-01 2023-12-12 Matrexa LLC Recombinant versican isoforms and related compositions and methods
KR20220044276A (ko) 2019-08-06 2022-04-07 바이오크리스트파마슈티컬즈,인코포레이티드 혈장 칼리크레인 억제제의 공정-스케일 합성
US20230146256A1 (en) 2020-04-17 2023-05-11 Regents Of The University Of Minnesota SARS-CoV-2 SPIKE RECEPTOR BINDING DOMAIN AND COMPOSITIONS AND METHODS THEREOF
US11529335B2 (en) 2020-07-31 2022-12-20 University Of Iowa Research Foundation Compositions and methods for treating cancer
WO2022155332A1 (fr) 2021-01-13 2022-07-21 Blue Therapeutics, Inc. Méthodes de traitement du syndrome du côlon irritable
MX2023009729A (es) 2021-02-22 2023-09-25 Univ Minnesota Inmunomoduladores y conjugados de inmunomoduladores.
US11780828B2 (en) 2021-05-04 2023-10-10 Regents Of The University Of Minnesota Contraceptive compounds and methods
WO2023081237A1 (fr) 2021-11-03 2023-05-11 Regents Of The University Of Minnesota Agonistes et antagonistes du récepteur de type toll et leurs utilisations
WO2023091689A1 (fr) 2021-11-19 2023-05-25 University Of Iowa Research Foundation Utilisation associée de radiothérapie dirigée par mcr1 et d'inhibition du point de contrôle immunitaire dans le traitement d'un mélanome
WO2024006977A1 (fr) 2022-07-01 2024-01-04 University Of Southern California Ligands bitopiques du récepteur opioïde delta analgésique
WO2024009283A1 (fr) 2022-07-07 2024-01-11 University Of Southern California Antagonistes at2 pour soulager la douleur non addictive
TW202409024A (zh) 2022-07-08 2024-03-01 美商愛克堤歐生物科學公司 治療性化合物及方法
WO2024102342A1 (fr) 2022-11-10 2024-05-16 University Of Iowa Research Foundation Combinaison d'un inhibiteur de la synthèse du glutathion tel que la buthionine sulfoximine et d'un inhibiteur de point de contrôle immunitaire, de préférence le pembrolizumab, pour traiter le cancer, de préférence un mélanome résistant aux médicaments
WO2024112932A1 (fr) 2022-11-23 2024-05-30 Regents Of The University Of Minnesota Immunomodulateurs et conjugués immunomodulateurs
WO2024124023A2 (fr) 2022-12-07 2024-06-13 Rutgers, The State University Of New Jersey Inhibiteurs d'enzyme anhydrase carbonique et leurs procédés d'utilisation

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE894110C (de) * 1951-07-19 1953-10-22 Basf Ag Verfahren zur Herstellung von Polyaethern
CH456045A (de) * 1963-02-25 1968-05-15 Ciba Geigy Hautpflegemittel
US3988377A (en) * 1965-10-22 1976-10-26 Lever Brothers Company Hydroxy substituted sulfoxides and thiothers
US3427248A (en) * 1965-10-22 1969-02-11 Lever Brothers Ltd Detergent
LU70718A1 (fr) * 1974-08-12 1976-08-19
JPS5251035A (en) * 1975-10-21 1977-04-23 Shiseido Co Ltd Cosmetics for hair dressing
LU73632A1 (fr) * 1975-10-23 1977-05-31
DE2640505C2 (de) * 1976-09-09 1978-08-31 Hoechst Ag, 6000 Frankfurt Verfahren zur Herstellung von Aethern
US4171455A (en) * 1978-09-19 1979-10-16 Shiseido Company Ltd. Polyoxypropylene polyoxyethylene addition ether of higher branched primary saturated alcohol
DE2850058A1 (de) * 1978-11-18 1980-05-29 Bayer Ag Polyaether-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
FR2467838A1 (fr) * 1979-10-16 1981-04-30 Oreal Nouveaux composes non-ioniques polyoxyethylenes a deux chaines lipophiles, leur procede de preparation et compositions les contenant
DE3026448A1 (de) * 1980-07-12 1982-02-04 Bayer Ag, 5090 Leverkusen Antitumoral wirkende mittel
US4486406A (en) * 1981-01-20 1984-12-04 Kao Soap Co, Ltd. Hair rinse composition
DE3121139A1 (de) * 1981-05-27 1982-12-16 Henkel KGaA, 4000 Düsseldorf "klebstoffe auf basis von cyanacrylsaeureestern"
JPS5883606A (ja) * 1981-11-10 1983-05-19 Kao Corp 毛髪処理剤
FR2516791B1 (fr) * 1981-11-24 1986-08-29 Oreal Vernis a ongles contenant en tant que resine du polytetrahydrofuranne

Also Published As

Publication number Publication date
LU84979A1 (fr) 1985-04-24
GB2145627A (en) 1985-04-03
GB2145627B (en) 1986-07-09
DE3431755C2 (de) 1993-11-11
JPS6078914A (ja) 1985-05-04
FR2550940A1 (fr) 1985-03-01
DE3431755A1 (de) 1985-03-14
US4608392A (en) 1986-08-26
GB8421946D0 (en) 1984-10-03

Similar Documents

Publication Publication Date Title
FR2550940B1 (fr) Composition cosmetique ou pharmaceutique sous forme aqueuse ou anhydre contenant, en tant que produit gras, un polyether oligomere
DE69319440D1 (de) Herstellung von pharmazeutischen zusammensetzungen, die calcitonin enthalten
FR2602974B1 (fr) Composition pharmaceutique contenant de la nicotine ou ses derives
BE880002A (fr) Procede de production d'une mousse de polyurethanne contenant une substance odorante et produit obtenu
MC2094A1 (fr) Medicament contenant de l'acide dihydrolipoique en tant que substance active,procede de preparation
DE3579128D1 (de) 13-cis-vitamin-a-saeure als wirksubstanz enthaltende arzneimittel.
FR2608426B1 (fr) Produit et procede pour un traitement hydratant efficace de la peau, utile notamment dans le domaine cosmetique
FR2527597B1 (fr) Derives d'alcool b,g-dihydropolyprenylique et composition pharmaceutique contenant un compose polyprenylique
GB8727099D0 (en) Compositions containing melantonin/homologues
BE828581A (fr) Produit pour le soins et la protection de la peau, contenant des hydroxydiamines comme agents hydratants
BE879472A (fr) Composition pharmaceutique contenant des 3,4-dihydro-3-oxo-2-quinoxalines
FR2608921B1 (fr) Composition pharmaceutique contenant de la ranitidine
KR910021361A (ko) 항궤양 물질
FR2628419B1 (fr) Nouveaux sels antiviraux, compositions pharmaceutiques les contenant et procede pour les preparer
FR2531336B1 (fr) Composition contenant de l'imidazolidinyluree et des parabenates, utile comme conservateur en cosmetique, compatible avec les produits a base aqueuse
FR2654111B1 (fr) Collagene, procede pour le preparer, et agent cosmetique le contenant.
PT66489B (fr) Procede pour la preparation des produits pharmaceutique contenant polihydroxiphenil cromanones
IT7924769A0 (it) Derivati di acidi aziridin-2-carbossilici n-sostituiti con attivita'immunostimolante, processi per laloro preparazione e farmaci contenenti tali sostanze.
FR2595705B1 (fr) Derives de gonadoliberine contenant un acide aminocarboxylique aromatique en position 6, compositions pharmaceutiques et veterinaires les contenant et procede pour les preparer
OA08130A (fr) Compositions pharmaceutiques ou vétérinaires contenant des dérivés thiosulfonates.
FR2726267B1 (fr) Nouveaux agents anti-arythmiques, compositions pharmaceutiques les contenant, et procede pour les preparer
BE864027A (fr) Procede de preparation de l'alpha-2,5,9-trimethylbenzo-(b)-thieno-(2,3,f)-morphane, produit obtenu et composition pharmaceutique le contenant
KR840005344A (ko) 털 나는 약
FR2609392B1 (fr) Compositions pharmaceutiques contenant des pyranoquinoleines
FR2470110B1 (fr) Derives de la decrapenylamine, leurs sels acides d'addition et composition pharmaceutique renfermant ces produits

Legal Events

Date Code Title Description
ST Notification of lapse