FR2372810B1 - - Google Patents

Info

Publication number
FR2372810B1
FR2372810B1 FR7802775A FR7802775A FR2372810B1 FR 2372810 B1 FR2372810 B1 FR 2372810B1 FR 7802775 A FR7802775 A FR 7802775A FR 7802775 A FR7802775 A FR 7802775A FR 2372810 B1 FR2372810 B1 FR 2372810B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7802775A
Other versions
FR2372810A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of FR2372810A1 publication Critical patent/FR2372810A1/fr
Application granted granted Critical
Publication of FR2372810B1 publication Critical patent/FR2372810B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom
    • C07D233/36—One oxygen atom with hydrocarbon radicals, substituted by nitrogen atoms, attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Laminated Bodies (AREA)
  • Nonwoven Fabrics (AREA)
  • Hydrogenated Pyridines (AREA)
  • Quinoline Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
FR7802775A 1976-03-09 1978-02-01 Nouvelles aminoalcoylimidazolidinones, procedes pour leur preparation et leur utilisation en tant que medicaments Granted FR2372810A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762609645 DE2609645A1 (de) 1976-03-09 1976-03-09 Aminoalkylheterocyclen

Publications (2)

Publication Number Publication Date
FR2372810A1 FR2372810A1 (fr) 1978-06-30
FR2372810B1 true FR2372810B1 (fr) 1982-11-26

Family

ID=5971857

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7707018A Granted FR2343731A1 (fr) 1976-03-09 1977-03-09 Nouveaux aminoalcoylheterocycles, procedes pour leur preparation et leur utilisation en tant que medicaments
FR7802775A Granted FR2372810A1 (fr) 1976-03-09 1978-02-01 Nouvelles aminoalcoylimidazolidinones, procedes pour leur preparation et leur utilisation en tant que medicaments

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR7707018A Granted FR2343731A1 (fr) 1976-03-09 1977-03-09 Nouveaux aminoalcoylheterocycles, procedes pour leur preparation et leur utilisation en tant que medicaments

Country Status (36)

Country Link
US (4) US4154829A (fr)
JP (2) JPS52108970A (fr)
AT (1) AT360542B (fr)
AU (1) AU515953B2 (fr)
BE (1) BE852223A (fr)
BG (4) BG28051A4 (fr)
CA (1) CA1086317A (fr)
CH (8) CH630358A5 (fr)
CS (2) CS209435B2 (fr)
DD (1) DD130037A5 (fr)
DE (1) DE2609645A1 (fr)
DK (1) DK102177A (fr)
ES (10) ES456622A1 (fr)
FI (1) FI69070C (fr)
FR (2) FR2343731A1 (fr)
GB (1) GB1571231A (fr)
GR (1) GR64553B (fr)
HK (1) HK12884A (fr)
HU (1) HU177953B (fr)
IE (1) IE45300B1 (fr)
IL (1) IL51627A (fr)
LU (1) LU76898A1 (fr)
MX (1) MX4878E (fr)
MY (1) MY8500079A (fr)
NL (1) NL7702403A (fr)
NO (1) NO147950C (fr)
NZ (1) NZ183536A (fr)
PH (3) PH16110A (fr)
PL (2) PL111240B1 (fr)
PT (1) PT66282B (fr)
RO (3) RO70569A (fr)
SE (1) SE435059B (fr)
SG (1) SG55583G (fr)
SU (4) SU698530A3 (fr)
YU (1) YU62377A (fr)
ZA (1) ZA771412B (fr)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2609645A1 (de) * 1976-03-09 1977-09-15 Boehringer Sohn Ingelheim Aminoalkylheterocyclen
DE2644833A1 (de) * 1976-10-05 1978-04-20 Boehringer Sohn Ingelheim Neue 1-aryloxy-2-hydroxy-3-alkylenaminopropane und verfahren zu ihrer herstellung
DE2833140A1 (de) * 1978-07-28 1980-02-07 Boehringer Sohn Ingelheim Neue n-substituierte heterocyclen
DK187980A (da) 1979-05-04 1980-11-05 Continental Pharma Fremgangsmaade til fremstilling af benzimidazolderivater
DE3026534A1 (de) * 1980-07-12 1982-03-18 C.H. Boehringer Sohn, 6507 Ingelheim 3,1-benzoxazin-2-one, ihre herstellung und verwendung
US4460581A (en) * 1982-10-12 1984-07-17 Boehringer Ingelheim Kg (1-Hydroxy-2-amino-alkyl)-substituted benzoxazinones and benzoxazolinones
DE3325875A1 (de) * 1983-07-18 1985-01-31 Boehringer Ingelheim KG, 6507 Ingelheim Neue 1-phenylimidazolidin-2-on-derivate, ihre herstellung und verwendung
US4743613A (en) * 1986-04-08 1988-05-10 Smithkline Beckman Corporation Ester prodrugs of dopamine-β-hydroxylase, inhibitors, composition containing them, and method of using them to inhibit dopamine-β-hydroxylase activity
GB8609331D0 (en) * 1986-04-16 1986-05-21 Pfizer Ltd Anti-arrythmia agents
TW203049B (fr) * 1990-04-13 1993-04-01 Yamanouchi Pharma Co Ltd
ZA967892B (en) * 1995-09-21 1998-03-18 Lilly Co Eli Selective β3 adrenergic agonists.
US5808080A (en) 1996-09-05 1998-09-15 Eli Lilly And Company Selective β3 adrenergic agonists
EP0827746B1 (fr) 1996-09-05 2002-04-03 Eli Lilly And Company Analogues de carbazole étant agonistes beta3-adrénergiques sélectifs
CO5011072A1 (es) 1997-12-05 2001-02-28 Lilly Co Eli Etanolaminas pirazinil substituidas como agfonistas de los receptores
EP1598340B1 (fr) 2001-04-18 2009-03-04 Euro-Celtique S.A. Derivés de la 1-(4-piperidinyl)-1,3-dihydro-2h-benzoxazole-2-one et composés similaires pour l'utilisation comme analogues du nociceptin et ligands du orl1 pour le traitement de la douleur
ATE403429T1 (de) 2001-04-18 2008-08-15 Euro Celtique Sa Spiropyrazol-verbindungen
CA2443938C (fr) 2001-04-18 2010-06-22 R. Richard Goehring Composes de spiroindene et de spiroindane comme ligands opioides utiles pour le traitement de la douleur
HUP0402510A3 (en) * 2001-04-18 2012-08-28 Euro Celtique Sa Nociceptin analogs and pharmaceutical compositions containing them
AU2002338424B2 (en) 2001-04-18 2005-04-21 Euro-Celtique S.A. Benzimidazolone compounds
US7056916B2 (en) 2002-11-15 2006-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments for the treatment of chronic obstructive pulmonary disease
CA2506741A1 (fr) * 2002-11-27 2004-06-17 Artesian Therapeutics, Inc. Composes presentant une activite mixte d'inhibition de la pde et d'antagoniste ou d'agoniste partiel beta-adrenergique pour traiter l'insuffisance cardiaque
WO2004058726A2 (fr) * 2002-12-23 2004-07-15 Artesian Therapeutics, Inc. Composes cardiotoniques a activite inhibitrice sur les recepteurs adrenergiques $g(b) et la phosphodiesterase
DE102004001413A1 (de) * 2004-01-09 2005-08-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg 3-Hydroxymethyl-4-Hydroxy-Phenyl-Derivate zur Behandlung von chronisch obstruktiver Lungenerkrankung
DE102004003428A1 (de) * 2004-01-23 2005-08-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue langwirksame Beta-2-Agonisten, und deren Verwendung als Arzneimittel
US20050272726A1 (en) * 2004-04-22 2005-12-08 Boehringer Ingelheim International Gmbh Novel medicaments for the treatment of respiratory diseases
DE102004021779A1 (de) * 2004-04-30 2005-11-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
US20050255050A1 (en) * 2004-05-14 2005-11-17 Boehringer Ingelheim International Gmbh Powder formulations for inhalation, comprising enantiomerically pure beta agonists
US7220742B2 (en) * 2004-05-14 2007-05-22 Boehringer Ingelheim International Gmbh Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
US20050256115A1 (en) * 2004-05-14 2005-11-17 Boehringer Ingelheim International Gmbh Aerosol formulation for the inhalation of beta-agonists
DE102004045648A1 (de) * 2004-09-21 2006-03-23 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Betamimetika zur Behandlung von Atemwegserkrankungen
JP2008521806A (ja) * 2004-11-30 2008-06-26 アーテシアン セラピューティクス， インコーポレイテッド 心不全を治療するための混合型のＰＤＥ−阻害活性およびβ−アドレナリン作用性アンタゴニスト活性または部分アゴニスト活性を有する化合物
EP1833480A2 (fr) * 2004-11-30 2007-09-19 Artesian Therapeutics, Inc. Composes cardiotoniques dotes d'une activite inhibitrice dirigee contre les recepteurs beta-adrenergiques et la phosphodiesterase
DE102005007654A1 (de) * 2005-02-19 2006-08-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue langwirksame Betamimetika zur Behandlung von Atemwegserkrankungen
DE102005030733A1 (de) * 2005-07-01 2007-01-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen enthaltend langwirksame Beta-2-Agonisten und wenigstens einen weiteren Wirkstoff
AU2006281449B2 (en) * 2005-08-15 2013-01-31 Boehringer Ingelheim International Gmbh Method for producing betamimetics
DE102005052127A1 (de) * 2005-10-28 2007-05-03 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue indol-haltige Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
DE102005052101A1 (de) * 2005-10-28 2007-05-03 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
DE102005052102A1 (de) * 2005-10-28 2007-05-03 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
EP1986644A1 (fr) * 2006-02-16 2008-11-05 Boehringer Ingelheim International GmbH Combinaisons medicamenteuses pour le traitement de pathologies des voies respiratoires
PE20080142A1 (es) 2006-03-15 2008-04-14 Boehringer Ingelheim Int Beta-agonistas enantiomericamente puros y sus procedimientos de preparacion
US20090324510A1 (en) 2006-08-07 2009-12-31 Boehringer Ingelheim International Gmbh Drug combinations for the treatment of respiratory tract diseases
US8686008B2 (en) * 2007-08-16 2014-04-01 The University Of Mississippi Highly selective sigma receptor ligands
US8809381B2 (en) * 2007-08-16 2014-08-19 The University Of Mississippi Highly selective sigma receptor ligands
US9604926B2 (en) 2007-08-16 2017-03-28 The University Of Mississippi Highly selective sigma receptor radioligands

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA631296A (en) * 1961-11-21 L. Clark Robert Substituted benzimidazolones
CH149009A (de) * 1929-08-10 1931-08-15 Chem Ind Basel Verfahren zur Darstellung einer N-substituierten Verbindung der Pyridonreihe.
US2857394A (en) * 1957-05-10 1958-10-21 Ciba Pharm Prod Inc Heterocyclic compounds
NL284529A (fr) * 1961-10-24
FR1516714A (fr) * 1962-11-07 1968-02-05 Bayer Ag Procédé de préparation de dérivés de l'imidazolidine
FR1384708A (fr) * 1963-11-21 1965-01-08 Thomson Houston Comp Francaise Perfectionnements aux dispositifs de mise en place d'objets
BE659364A (fr) * 1964-02-05
US3355457A (en) * 1965-05-21 1967-11-28 American Cyanamid Co Substituted 2-imidazolinones
FR1573739A (fr) * 1968-07-26 1969-07-04
US3984405A (en) * 1971-06-28 1976-10-05 E. R. Squibb & Sons, Inc. Anti-inflammatory agents
BE787103A (fr) * 1971-08-04 1973-02-02 Pfizer Nouveaux derives de propanolamine et composition pharmaceutiqueles contenant
FR2168140A1 (en) * 1972-01-17 1973-08-31 Bellon Labor Sa Roger Dihydro-benzoxazine derivs - antidepressants
US3925383A (en) * 1972-12-08 1975-12-09 Janssen Pharmaceutica Nv Bicyclic imidazoles and pyrimidines
US3994901A (en) * 1974-06-13 1976-11-30 Otsuka Pharmaceutical Company Limited 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-hydroxy-3,4-dihydrocarbostyril derivatives
US4081447A (en) * 1975-04-09 1978-03-28 Abbott Laboratories 5-[2-Hydroxy-3-(3,4-dimethoxy phenethylamino)]-propoxy-3,4-dihydro carbostyril and pharmaceutically acceptable salts thereof
DE2609645A1 (de) * 1976-03-09 1977-09-15 Boehringer Sohn Ingelheim Aminoalkylheterocyclen

Also Published As

Publication number Publication date
CH630359A5 (de) 1982-06-15
SG55583G (en) 1984-07-27
ES466601A1 (es) 1978-10-01
CH630361A5 (de) 1982-06-15
SE435059B (sv) 1984-09-03
ES466604A1 (es) 1978-10-01
ES456622A1 (es) 1978-03-16
PT66282B (pt) 1979-01-17
NO147950B (no) 1983-04-05
RO79706A (fr) 1982-08-17
FR2343731A1 (fr) 1977-10-07
SU698530A3 (ru) 1979-11-15
MY8500079A (en) 1985-12-31
NO147950C (no) 1983-07-13
BG28051A4 (en) 1980-02-25
SE7702609L (sv) 1977-10-11
IL51627A (en) 1980-10-26
BG27743A3 (en) 1979-12-12
DD130037A5 (de) 1978-03-01
US4271158A (en) 1981-06-02
RO70569A (fr) 1981-11-24
BE852223A (fr) 1977-09-08
ES466600A1 (es) 1978-10-01
CA1086317A (fr) 1980-09-23
HK12884A (en) 1984-02-24
CH630362A5 (de) 1982-06-15
CH630358A5 (de) 1982-06-15
CS220320B2 (en) 1983-03-25
CH630363A5 (de) 1982-06-15
PT66282A (pt) 1977-04-01
ES466605A1 (es) 1978-10-01
NO770804L (no) 1977-09-12
YU62377A (en) 1982-10-31
DK102177A (da) 1977-09-10
PL112937B1 (en) 1980-11-29
FI69070B (fi) 1985-08-30
FI69070C (fi) 1985-12-10
GR64553B (en) 1980-04-14
JPS52108970A (en) 1977-09-12
ATA122377A (de) 1980-06-15
SU683616A3 (ru) 1979-08-30
PH16110A (en) 1983-06-30
IE45300B1 (en) 1982-07-28
JPS6172A (ja) 1986-01-06
ES466598A1 (es) 1978-10-01
BG28052A4 (en) 1980-02-25
ES466603A1 (es) 1978-10-01
IE45300L (en) 1977-09-09
PH17635A (en) 1984-10-18
CH630360A5 (de) 1982-06-15
RO76589A (fr) 1981-04-30
AU515953B2 (en) 1981-05-14
BG28053A4 (en) 1980-02-25
GB1571231A (en) 1980-07-09
ES466599A1 (es) 1978-10-01
FR2343731B1 (fr) 1982-02-26
IL51627A0 (en) 1977-05-31
SU685149A3 (ru) 1979-09-05
MX4878E (es) 1982-11-26
SU676163A3 (ru) 1979-07-25
ZA771412B (en) 1978-11-29
US4154829A (en) 1979-05-15
ES466602A1 (es) 1978-10-01
FI770586A (fr) 1977-09-10
NZ183536A (en) 1981-11-19
FR2372810A1 (fr) 1978-06-30
CH630364A5 (de) 1982-06-15
LU76898A1 (fr) 1978-06-01
HU177953B (en) 1982-02-28
US4215119A (en) 1980-07-29
NL7702403A (nl) 1977-09-13
DE2609645A1 (de) 1977-09-15
PL111240B1 (en) 1980-08-30
ES466606A1 (es) 1978-10-01
CH630365A5 (de) 1982-06-15
CS209435B2 (en) 1981-12-31
AT360542B (de) 1981-01-12
PL196505A1 (pl) 1979-06-18
AU2300977A (en) 1978-09-14
US4363814A (en) 1982-12-14
PH16149A (en) 1983-07-12

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