BG28051A4 - Method of obtaining of aminoalkyl-heterocycles - Google Patents

Method of obtaining of aminoalkyl-heterocycles

Info

Publication number
BG28051A4
BG28051A4 BG7736628A BG3662877A BG28051A4 BG 28051 A4 BG28051 A4 BG 28051A4 BG 7736628 A BG7736628 A BG 7736628A BG 3662877 A BG3662877 A BG 3662877A BG 28051 A4 BG28051 A4 BG 28051A4
Authority
BG
Bulgaria
Prior art keywords
aminoalkyl
heterocycles
obtaining
Prior art date
Application number
BG7736628A
Other languages
Bulgarian (bg)
English (en)
Inventor
Mentrup
Schromm
Renth
Reichl
Traunecker
Hoefke
Original Assignee
C.H. Boehringer Sohn,De
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by C.H. Boehringer Sohn,De filed Critical C.H. Boehringer Sohn,De
Publication of BG28051A4 publication Critical patent/BG28051A4/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom
    • C07D233/36—One oxygen atom with hydrocarbon radicals, substituted by nitrogen atoms, attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
BG7736628A 1976-03-09 1977-03-07 Method of obtaining of aminoalkyl-heterocycles BG28051A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762609645 DE2609645A1 (de) 1976-03-09 1976-03-09 Aminoalkylheterocyclen

Publications (1)

Publication Number Publication Date
BG28051A4 true BG28051A4 (en) 1980-02-25

Family

ID=5971857

Family Applications (4)

Application Number Title Priority Date Filing Date
BG7735601A BG27743A3 (en) 1976-03-09 1977-03-07 Method of obtaining of aminoalkylheterocycles
BG7736628A BG28051A4 (en) 1976-03-09 1977-03-07 Method of obtaining of aminoalkyl-heterocycles
BG7736629A BG28052A4 (en) 1976-03-09 1977-03-07 Method of obtaining of aminoalkyl-heterocycles
BG7836630A BG28053A4 (en) 1976-03-09 1978-06-14 Method of obtaining of aminoalkyl-heterocycles

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BG7735601A BG27743A3 (en) 1976-03-09 1977-03-07 Method of obtaining of aminoalkylheterocycles

Family Applications After (2)

Application Number Title Priority Date Filing Date
BG7736629A BG28052A4 (en) 1976-03-09 1977-03-07 Method of obtaining of aminoalkyl-heterocycles
BG7836630A BG28053A4 (en) 1976-03-09 1978-06-14 Method of obtaining of aminoalkyl-heterocycles

Country Status (36)

Country Link
US (4) US4154829A (fr)
JP (2) JPS52108970A (fr)
AT (1) AT360542B (fr)
AU (1) AU515953B2 (fr)
BE (1) BE852223A (fr)
BG (4) BG27743A3 (fr)
CA (1) CA1086317A (fr)
CH (8) CH630358A5 (fr)
CS (2) CS209435B2 (fr)
DD (1) DD130037A5 (fr)
DE (1) DE2609645A1 (fr)
DK (1) DK102177A (fr)
ES (10) ES456622A1 (fr)
FI (1) FI69070C (fr)
FR (2) FR2343731A1 (fr)
GB (1) GB1571231A (fr)
GR (1) GR64553B (fr)
HK (1) HK12884A (fr)
HU (1) HU177953B (fr)
IE (1) IE45300B1 (fr)
IL (1) IL51627A (fr)
LU (1) LU76898A1 (fr)
MX (1) MX4878E (fr)
MY (1) MY8500079A (fr)
NL (1) NL7702403A (fr)
NO (1) NO147950C (fr)
NZ (1) NZ183536A (fr)
PH (3) PH16110A (fr)
PL (2) PL111240B1 (fr)
PT (1) PT66282B (fr)
RO (3) RO76589A (fr)
SE (1) SE435059B (fr)
SG (1) SG55583G (fr)
SU (4) SU698530A3 (fr)
YU (1) YU62377A (fr)
ZA (1) ZA771412B (fr)

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* Cited by examiner, † Cited by third party
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DE2609645A1 (de) * 1976-03-09 1977-09-15 Boehringer Sohn Ingelheim Aminoalkylheterocyclen
DE2644833A1 (de) * 1976-10-05 1978-04-20 Boehringer Sohn Ingelheim Neue 1-aryloxy-2-hydroxy-3-alkylenaminopropane und verfahren zu ihrer herstellung
DE2833140A1 (de) * 1978-07-28 1980-02-07 Boehringer Sohn Ingelheim Neue n-substituierte heterocyclen
SE8003278L (sv) 1979-05-04 1980-11-05 Continental Pharma Fenyletylaminderivat
DE3026534A1 (de) * 1980-07-12 1982-03-18 C.H. Boehringer Sohn, 6507 Ingelheim 3,1-benzoxazin-2-one, ihre herstellung und verwendung
US4460581A (en) * 1982-10-12 1984-07-17 Boehringer Ingelheim Kg (1-Hydroxy-2-amino-alkyl)-substituted benzoxazinones and benzoxazolinones
DE3325875A1 (de) * 1983-07-18 1985-01-31 Boehringer Ingelheim KG, 6507 Ingelheim Neue 1-phenylimidazolidin-2-on-derivate, ihre herstellung und verwendung
US4743613A (en) * 1986-04-08 1988-05-10 Smithkline Beckman Corporation Ester prodrugs of dopamine-β-hydroxylase, inhibitors, composition containing them, and method of using them to inhibit dopamine-β-hydroxylase activity
GB8609331D0 (en) * 1986-04-16 1986-05-21 Pfizer Ltd Anti-arrythmia agents
TW203049B (fr) * 1990-04-13 1993-04-01 Yamanouchi Pharma Co Ltd
ZA967892B (en) * 1995-09-21 1998-03-18 Lilly Co Eli Selective β3 adrenergic agonists.
ATE215369T1 (de) * 1996-09-05 2002-04-15 Lilly Co Eli Carbazolanaloge als selektive beta3-adrenergische agonisten
US5808080A (en) 1996-09-05 1998-09-15 Eli Lilly And Company Selective β3 adrenergic agonists
CO5011072A1 (es) 1997-12-05 2001-02-28 Lilly Co Eli Etanolaminas pirazinil substituidas como agfonistas de los receptores
EP1918279A3 (fr) 2001-04-18 2008-07-16 Euro-Celtique S.A. Dérivés de la 1-(4-pipéridinyl)-1,3-dihydro-2h-benzoxazole-2-one et composés similaires en tant que analogues de la nociceptine et ligandes du récepteur resemblant le récepteur opioid pour le traitement de la douleur
DK1975164T3 (da) 2001-04-18 2010-05-25 Euro Celtique Sa Octahydrobenzimidazolon-forbindelser som analgetika
ES2316559T3 (es) 2001-04-18 2009-04-16 Euro-Celtique S.A. Compuestos espiroindeno y espiroindano.
HUP0401333A3 (en) 2001-04-18 2004-11-29 Euro Celtique Sa Spiropyrazole compounds and pharmaceutical compositions containing them
MXPA03009602A (es) * 2001-04-18 2004-04-02 Euro Celtique Sa Analogos de nociceptina.
US7056916B2 (en) 2002-11-15 2006-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments for the treatment of chronic obstructive pulmonary disease
EP1565472A2 (fr) * 2002-11-27 2005-08-24 Artesian Therapeutics, Inc. Composes presentant une activite mixte d'inhibition de la pde et d'antagoniste ou d'agoniste partiel beta-adrenergique pour traiter l'insuffisance cardiaque
JP2006513222A (ja) * 2002-12-23 2006-04-20 アルテシアン セラピューティック，インコーポレイティド アドレナリン性β受容体およびホスホジエステラーゼに対する抑制活性を有する強心性化合物
DE102004001413A1 (de) * 2004-01-09 2005-08-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg 3-Hydroxymethyl-4-Hydroxy-Phenyl-Derivate zur Behandlung von chronisch obstruktiver Lungenerkrankung
DE102004003428A1 (de) * 2004-01-23 2005-08-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue langwirksame Beta-2-Agonisten, und deren Verwendung als Arzneimittel
US20050272726A1 (en) * 2004-04-22 2005-12-08 Boehringer Ingelheim International Gmbh Novel medicaments for the treatment of respiratory diseases
DE102004021779A1 (de) * 2004-04-30 2005-11-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
US20050255050A1 (en) * 2004-05-14 2005-11-17 Boehringer Ingelheim International Gmbh Powder formulations for inhalation, comprising enantiomerically pure beta agonists
US7220742B2 (en) * 2004-05-14 2007-05-22 Boehringer Ingelheim International Gmbh Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
US20050256115A1 (en) * 2004-05-14 2005-11-17 Boehringer Ingelheim International Gmbh Aerosol formulation for the inhalation of beta-agonists
DE102004045648A1 (de) * 2004-09-21 2006-03-23 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Betamimetika zur Behandlung von Atemwegserkrankungen
WO2006060127A2 (fr) * 2004-11-30 2006-06-08 Artesian Therapeutics, Inc. Composes a activite a la fois inhibitrice de la pde et antagoniste ou agoniste partielle des recepteurs $g(b)-adrenergiques pour le traitement de l'insuffisance cardiaque
JP2008521805A (ja) * 2004-11-30 2008-06-26 アーテシアン セラピューティクス， インコーポレイテッド β−アドレナリン作用性受容体およびホスホジエステラーゼに対する阻害活性を有する強心性化合物
DE102005007654A1 (de) * 2005-02-19 2006-08-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue langwirksame Betamimetika zur Behandlung von Atemwegserkrankungen
DE102005030733A1 (de) * 2005-07-01 2007-01-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen enthaltend langwirksame Beta-2-Agonisten und wenigstens einen weiteren Wirkstoff
JP5270343B2 (ja) * 2005-08-15 2013-08-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ベータミメティックスの製造方法
DE102005052101A1 (de) * 2005-10-28 2007-05-03 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
DE102005052127A1 (de) * 2005-10-28 2007-05-03 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue indol-haltige Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
DE102005052102A1 (de) * 2005-10-28 2007-05-03 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
WO2007093608A1 (fr) * 2006-02-16 2007-08-23 Boehringer Ingelheim International Gmbh Combinaisons médicamenteuses pour le traitement de pathologies des voies respiratoires
PE20080142A1 (es) * 2006-03-15 2008-04-14 Boehringer Ingelheim Int Beta-agonistas enantiomericamente puros y sus procedimientos de preparacion
US20090324510A1 (en) 2006-08-07 2009-12-31 Boehringer Ingelheim International Gmbh Drug combinations for the treatment of respiratory tract diseases
US9604926B2 (en) 2007-08-16 2017-03-28 The University Of Mississippi Highly selective sigma receptor radioligands
US8686008B2 (en) * 2007-08-16 2014-04-01 The University Of Mississippi Highly selective sigma receptor ligands
WO2009026227A2 (fr) * 2007-08-16 2009-02-26 The University Of Mississippi Ligands de récepteur sigma hautement sélectifs

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CA631296A (en) * 1961-11-21 L. Clark Robert Substituted benzimidazolones
CH149009A (de) * 1929-08-10 1931-08-15 Chem Ind Basel Verfahren zur Darstellung einer N-substituierten Verbindung der Pyridonreihe.
US2857394A (en) * 1957-05-10 1958-10-21 Ciba Pharm Prod Inc Heterocyclic compounds
NL284529A (fr) * 1961-10-24
FR1516714A (fr) * 1962-11-07 1968-02-05 Bayer Ag Procédé de préparation de dérivés de l'imidazolidine
FR1384708A (fr) * 1963-11-21 1965-01-08 Thomson Houston Comp Francaise Perfectionnements aux dispositifs de mise en place d'objets
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FR1573739A (fr) * 1968-07-26 1969-07-04
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BE787103A (fr) * 1971-08-04 1973-02-02 Pfizer Nouveaux derives de propanolamine et composition pharmaceutiqueles contenant
FR2168140A1 (en) * 1972-01-17 1973-08-31 Bellon Labor Sa Roger Dihydro-benzoxazine derivs - antidepressants
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DE2609645A1 (de) * 1976-03-09 1977-09-15 Boehringer Sohn Ingelheim Aminoalkylheterocyclen

Also Published As

Publication number Publication date
BG28052A4 (en) 1980-02-25
ES456622A1 (es) 1978-03-16
ZA771412B (en) 1978-11-29
IL51627A (en) 1980-10-26
ATA122377A (de) 1980-06-15
ES466598A1 (es) 1978-10-01
BG28053A4 (en) 1980-02-25
ES466606A1 (es) 1978-10-01
FI69070B (fi) 1985-08-30
LU76898A1 (fr) 1978-06-01
PH17635A (en) 1984-10-18
FR2372810B1 (fr) 1982-11-26
DD130037A5 (de) 1978-03-01
GB1571231A (en) 1980-07-09
PL196505A1 (pl) 1979-06-18
RO79706A (fr) 1982-08-17
NO147950B (no) 1983-04-05
NO147950C (no) 1983-07-13
DK102177A (da) 1977-09-10
CH630360A5 (de) 1982-06-15
US4215119A (en) 1980-07-29
ES466601A1 (es) 1978-10-01
CS220320B2 (en) 1983-03-25
PH16110A (en) 1983-06-30
NL7702403A (nl) 1977-09-13
IE45300B1 (en) 1982-07-28
CH630358A5 (de) 1982-06-15
US4363814A (en) 1982-12-14
CH630365A5 (de) 1982-06-15
PL111240B1 (en) 1980-08-30
BG27743A3 (en) 1979-12-12
FR2343731A1 (fr) 1977-10-07
SU685149A3 (ru) 1979-09-05
IE45300L (en) 1977-09-09
ES466600A1 (es) 1978-10-01
HK12884A (en) 1984-02-24
MY8500079A (en) 1985-12-31
ES466599A1 (es) 1978-10-01
AU2300977A (en) 1978-09-14
FI69070C (fi) 1985-12-10
SE435059B (sv) 1984-09-03
BE852223A (fr) 1977-09-08
SG55583G (en) 1984-07-27
CS209435B2 (en) 1981-12-31
US4154829A (en) 1979-05-15
JPS52108970A (en) 1977-09-12
ES466602A1 (es) 1978-10-01
DE2609645A1 (de) 1977-09-15
PH16149A (en) 1983-07-12
PT66282A (pt) 1977-04-01
AT360542B (de) 1981-01-12
SE7702609L (sv) 1977-10-11
CH630362A5 (de) 1982-06-15
AU515953B2 (en) 1981-05-14
SU698530A3 (ru) 1979-11-15
FI770586A (fr) 1977-09-10
ES466605A1 (es) 1978-10-01
SU683616A3 (ru) 1979-08-30
CA1086317A (fr) 1980-09-23
YU62377A (en) 1982-10-31
NZ183536A (en) 1981-11-19
JPS6172A (ja) 1986-01-06
FR2343731B1 (fr) 1982-02-26
RO70569A (fr) 1981-11-24
HU177953B (en) 1982-02-28
PT66282B (pt) 1979-01-17
CH630364A5 (de) 1982-06-15
SU676163A3 (ru) 1979-07-25
RO76589A (fr) 1981-04-30
PL112937B1 (en) 1980-11-29
ES466604A1 (es) 1978-10-01
ES466603A1 (es) 1978-10-01
CH630361A5 (de) 1982-06-15
CH630363A5 (de) 1982-06-15
IL51627A0 (en) 1977-05-31
US4271158A (en) 1981-06-02
NO770804L (no) 1977-09-12
CH630359A5 (de) 1982-06-15
MX4878E (es) 1982-11-26
FR2372810A1 (fr) 1978-06-30
GR64553B (en) 1980-04-14

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