BG28414A4 - Method of obtaining of 1- hydroxytetramydrobenzo (c) hinolines - Google Patents

Method of obtaining of 1- hydroxytetramydrobenzo (c) hinolines

Info

Publication number
BG28414A4
BG28414A4 BG7737711A BG3771177A BG28414A4 BG 28414 A4 BG28414 A4 BG 28414A4 BG 7737711 A BG7737711 A BG 7737711A BG 3771177 A BG3771177 A BG 3771177A BG 28414 A4 BG28414 A4 BG 28414A4
Authority
BG
Bulgaria
Prior art keywords
hydroxytetramydrobenzo
hinolines
obtaining
Prior art date
Application number
BG7737711A
Inventor
Johnson
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of BG28414A4 publication Critical patent/BG28414A4/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
    • C07C43/1782—Unsaturated ethers containing hydroxy or O-metal groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/205—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring
    • C07C43/2055—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring containing more than one ether bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/255—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/10—Aza-phenanthrenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/10—Aza-phenanthrenes
    • C07D221/12—Phenanthridines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5456—Arylalkanephosphonium compounds
BG7737711A 1976-05-17 1977-05-17 Method of obtaining of 1- hydroxytetramydrobenzo (c) hinolines BG28414A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US68733276A 1976-05-17 1976-05-17
US75361976A 1976-12-22 1976-12-22
US77792877A 1977-03-15 1977-03-15

Publications (1)

Publication Number Publication Date
BG28414A4 true BG28414A4 (en) 1980-04-15

Family

ID=27418484

Family Applications (4)

Application Number Title Priority Date Filing Date
BG7737711A BG28414A4 (en) 1976-05-17 1977-05-17 Method of obtaining of 1- hydroxytetramydrobenzo (c) hinolines
BG7737712A BG28415A4 (en) 1976-05-17 1977-05-17 Method of obtaining of 9-hydroxyoctahydrobenzo (c) hynolines
BG7736340A BG27897A3 (en) 1976-05-17 1977-05-17 Method of obtaining of benzo (c) hinolines
BG7737713A BG28416A4 (en) 1976-05-17 1977-05-17 Method of obtaining of benzo (c) hinolines

Family Applications After (3)

Application Number Title Priority Date Filing Date
BG7737712A BG28415A4 (en) 1976-05-17 1977-05-17 Method of obtaining of 9-hydroxyoctahydrobenzo (c) hynolines
BG7736340A BG27897A3 (en) 1976-05-17 1977-05-17 Method of obtaining of benzo (c) hinolines
BG7737713A BG28416A4 (en) 1976-05-17 1977-05-17 Method of obtaining of benzo (c) hinolines

Country Status (23)

Country Link
JP (1) JPS6016426B2 (en)
AR (1) AR215896A1 (en)
BG (4) BG28414A4 (en)
CA (1) CA1095909A (en)
CH (2) CH626881A5 (en)
DD (1) DD130855A5 (en)
DE (1) DE2722383A1 (en)
DK (1) DK212677A (en)
ES (4) ES458812A1 (en)
FI (1) FI64141C (en)
FR (2) FR2362129A1 (en)
GR (1) GR74122B (en)
IL (1) IL52087A (en)
LU (1) LU77341A1 (en)
NL (2) NL170141C (en)
NO (1) NO147028C (en)
NZ (1) NZ184114A (en)
PH (1) PH16833A (en)
PT (1) PT66550B (en)
RO (1) RO76839A (en)
SE (1) SE7704749L (en)
SU (1) SU1098520A3 (en)
YU (2) YU156882A (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2802211A1 (en) * 1978-01-19 1979-07-26 Basf Ag N-SUBSTITUTED 2,6-DIALKYLANILINES AND METHOD FOR PREPARING N-SUBSTITUTED 2,6-DIALKYLANILINES
US4206225A (en) * 1978-09-22 1980-06-03 Pfizer Inc. 2,10-Disubstituted dibenzo[b,d]pyrans and benzo[c]quinolines
US4228169A (en) * 1979-06-26 1980-10-14 Pfizer Inc. 1,9-Dihydroxyoctahydrobenzo[c]quinolines and 1-hydroxyhexahydrobenzo[c]quinoline-9(8H)-ones as antiemetic agents
US4309545A (en) * 1980-07-28 1982-01-05 Pfizer Inc. Oximino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof
US4406888A (en) * 1981-01-09 1983-09-27 Pfizer Inc. Aqueous micellar solutions of levonantradol and N-methyllevonantradol and lyophilic forms thereof for reconstitution
HU194858B (en) * 1982-12-03 1988-03-28 Chinoin Gyogyszer Es Vegyeszet Process for producing dibenzo/b,d/pirane derivatives and pharmaceutical compositions containing them
CN102448920B (en) 2009-03-25 2016-04-06 Abbvie公司 Antiviral compound and its purposes

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3636058A (en) * 1966-03-25 1972-01-18 Hoffmann La Roche 7 10 - dihydro - 3 - alkyl - 6h - dibenzo(b d) pyran-6 9(8h)-diones and 5-hydroxy-7-alkyl-4-chromanones
US3507885A (en) * 1966-03-25 1970-04-21 Hoffmann La Roche 3-alkyl-6h-dibenzo(b,d)pyrans
US3649650A (en) * 1970-02-13 1972-03-14 Little Inc A Novel derivatives of tetrahydro-cannabinol
CA994791A (en) * 1971-05-12 1976-08-10 Louis S. Harris Esters of benzopyrans
US3856821A (en) * 1973-07-18 1974-12-24 Smithkline Corp ALKOXY DIBENZO (b,d) PYRANS
US3928598A (en) * 1973-11-05 1975-12-23 Lilly Co Eli Hexahydro-dibenzo{8 b,d{9 pyran-9-ones as an anti-anxiety drug
US3944673A (en) * 1973-11-05 1976-03-16 Eli Lilly And Company Hexahydro-dibenzo[b,d]pyran-9-ones as analgesic drugs
US3968125A (en) * 1973-11-05 1976-07-06 Eli Lilly And Company Dihydroxyhexahydrodibenzo[b,d]pyrans
GB1522057A (en) * 1975-11-03 1978-08-23 Pfizer 9-hydroxydibenzo(b,d)pyrans and intermediates therefor

Also Published As

Publication number Publication date
IL52087A0 (en) 1977-07-31
FR2446284A1 (en) 1980-08-08
NL7804461A (en) 1978-08-31
BG28416A4 (en) 1980-04-15
DE2722383C2 (en) 1990-06-07
IL52087A (en) 1981-11-30
DE2722383A1 (en) 1977-12-01
NO147028B (en) 1982-10-11
GR74122B (en) 1984-06-06
ES469203A1 (en) 1978-11-16
FI64141B (en) 1983-06-30
SE7704749L (en) 1977-12-05
AR215896A1 (en) 1979-11-15
ES469204A1 (en) 1978-11-16
FR2362129A1 (en) 1978-03-17
ES469202A1 (en) 1978-11-16
DK212677A (en) 1977-11-18
YU156982A (en) 1983-02-28
YU156882A (en) 1983-02-28
CA1095909A (en) 1981-02-17
NL7705433A (en) 1977-11-21
NO147028C (en) 1983-01-19
FI771550A (en) 1977-11-18
ES458812A1 (en) 1978-08-16
JPS52144672A (en) 1977-12-02
FI64141C (en) 1983-10-10
CH628034A5 (en) 1982-02-15
SU1098520A3 (en) 1984-06-15
RO76839A (en) 1981-05-30
NO771738L (en) 1977-11-18
LU77341A1 (en) 1977-12-13
FR2362129B1 (en) 1983-05-20
JPS6016426B2 (en) 1985-04-25
NZ184114A (en) 1982-02-23
CH626881A5 (en) 1981-12-15
BG28415A4 (en) 1980-04-15
DD130855A5 (en) 1978-05-10
PH16833A (en) 1984-03-06
NL170141C (en) 1982-10-01
PT66550B (en) 1978-10-18
BG27897A3 (en) 1980-01-15
PT66550A (en) 1977-06-01
FR2446284B1 (en) 1983-08-26
AU2516277A (en) 1978-06-22

Similar Documents

Publication Publication Date Title
BG28052A4 (en) Method of obtaining of aminoalkyl-heterocycles
BG28061A3 (en) Method of obtaining of hexahydrodibenzopyranones
BG33153A3 (en) Method for obtaining of 1- aryloxy- 2- hydroxy- 3- alkylene
BG27734A3 (en) Method of obtaining of m- aryloxybenzaldehydes
BG28068A3 (en) Method of obtaining of 3-chlorcephalosporines
BG28849A3 (en) Method of obtaining of gamapyrons
BG28071A3 (en) Method of obtaining of 2-deoxystreptamineaminoglucosides
BG28072A4 (en) Method of obtaining of 1-substitvated canamyzine derivatives
BG27754A3 (en) Method of obtaining of 3- halomethylcephems
BG28414A4 (en) Method of obtaining of 1- hydroxytetramydrobenzo (c) hinolines
BG28845A3 (en) Method of obtaining of n- alkyldiphenylamines
BG28055A3 (en) Method of obtaining of phenylperazine derivatives
BG28066A3 (en) Method of obtaining of pyridobenzodiazepinones
GR59194B (en) Preparation method of aryloxy-1 amino-3-propanols-2
BG27755A3 (en) Method of obtaining of 7- alkoxy- 3- chlormethilcephems
BG28417A3 (en) Method of obtaining of trans- 5a- aryldecahydrobenzazepine
BG31363A3 (en) Method for obtaining of haloacetamid
BG31074A3 (en) Method for obtaining of 1- oxadethiacefalosporine
JPS52121933A (en) Method of embanking
JPS5358596A (en) Method of making polyallylpolyamines
JPS5377090A (en) Method of etherizing
JPS52108937A (en) Method of polybrominating bissphenoxyalkane
GR63598B (en) Method of preparation of n-6-chloranicotinoylo-ocmocisteino-thiolactone
JPS5350169A (en) Preparation method of tetrazols
JPS5374148A (en) Method of falseetwisting