ES466605A1 - Procedimiento para la preparacion de heterociclos aminoal- cohilicos. - Google Patents
Procedimiento para la preparacion de heterociclos aminoal- cohilicos.Info
- Publication number
- ES466605A1 ES466605A1 ES466605A ES466605A ES466605A1 ES 466605 A1 ES466605 A1 ES 466605A1 ES 466605 A ES466605 A ES 466605A ES 466605 A ES466605 A ES 466605A ES 466605 A1 ES466605 A1 ES 466605A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- hydrogen
- alkyl
- trifluoromethyl
- halogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/32—One oxygen atom
- C07D233/36—One oxygen atom with hydrocarbon radicals, substituted by nitrogen atoms, attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Hydrogenated Pyridines (AREA)
- Quinoline Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Laminated Bodies (AREA)
- Nonwoven Fabrics (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19762609645 DE2609645A1 (de) | 1976-03-09 | 1976-03-09 | Aminoalkylheterocyclen |
Publications (1)
Publication Number | Publication Date |
---|---|
ES466605A1 true ES466605A1 (es) | 1978-10-01 |
Family
ID=5971857
Family Applications (10)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES456622A Expired ES456622A1 (es) | 1976-03-09 | 1977-03-08 | Procedimiento para la preparacion de heterociclos aminoalco-hilicos. |
ES466606A Expired ES466606A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoal- cohilicos. |
ES466605A Expired ES466605A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoal- cohilicos. |
ES466598A Expired ES466598A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoal- cohilicos. |
ES466602A Expired ES466602A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoal- cohilicos. |
ES466604A Expired ES466604A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoal- cohilicos. |
ES466603A Expired ES466603A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoalco-hilicos. |
ES466601A Expired ES466601A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoalco-hilicos. |
ES466600A Expired ES466600A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoal- cohilicos. |
ES466599A Expired ES466599A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoal- cohilicos. |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES456622A Expired ES456622A1 (es) | 1976-03-09 | 1977-03-08 | Procedimiento para la preparacion de heterociclos aminoalco-hilicos. |
ES466606A Expired ES466606A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoal- cohilicos. |
Family Applications After (7)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES466598A Expired ES466598A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoal- cohilicos. |
ES466602A Expired ES466602A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoal- cohilicos. |
ES466604A Expired ES466604A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoal- cohilicos. |
ES466603A Expired ES466603A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoalco-hilicos. |
ES466601A Expired ES466601A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoalco-hilicos. |
ES466600A Expired ES466600A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoal- cohilicos. |
ES466599A Expired ES466599A1 (es) | 1976-03-09 | 1978-02-03 | Procedimiento para la preparacion de heterociclos aminoal- cohilicos. |
Country Status (36)
Country | Link |
---|---|
US (4) | US4154829A (es) |
JP (2) | JPS52108970A (es) |
AT (1) | AT360542B (es) |
AU (1) | AU515953B2 (es) |
BE (1) | BE852223A (es) |
BG (4) | BG27743A3 (es) |
CA (1) | CA1086317A (es) |
CH (8) | CH630358A5 (es) |
CS (2) | CS220320B2 (es) |
DD (1) | DD130037A5 (es) |
DE (1) | DE2609645A1 (es) |
DK (1) | DK102177A (es) |
ES (10) | ES456622A1 (es) |
FI (1) | FI69070C (es) |
FR (2) | FR2343731A1 (es) |
GB (1) | GB1571231A (es) |
GR (1) | GR64553B (es) |
HK (1) | HK12884A (es) |
HU (1) | HU177953B (es) |
IE (1) | IE45300B1 (es) |
IL (1) | IL51627A (es) |
LU (1) | LU76898A1 (es) |
MX (1) | MX4878E (es) |
MY (1) | MY8500079A (es) |
NL (1) | NL7702403A (es) |
NO (1) | NO147950C (es) |
NZ (1) | NZ183536A (es) |
PH (3) | PH16110A (es) |
PL (2) | PL112937B1 (es) |
PT (1) | PT66282B (es) |
RO (3) | RO79706A (es) |
SE (1) | SE435059B (es) |
SG (1) | SG55583G (es) |
SU (4) | SU698530A3 (es) |
YU (1) | YU62377A (es) |
ZA (1) | ZA771412B (es) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2609645A1 (de) * | 1976-03-09 | 1977-09-15 | Boehringer Sohn Ingelheim | Aminoalkylheterocyclen |
DE2644833A1 (de) * | 1976-10-05 | 1978-04-20 | Boehringer Sohn Ingelheim | Neue 1-aryloxy-2-hydroxy-3-alkylenaminopropane und verfahren zu ihrer herstellung |
DE2833140A1 (de) * | 1978-07-28 | 1980-02-07 | Boehringer Sohn Ingelheim | Neue n-substituierte heterocyclen |
BE883069A (fr) | 1979-05-04 | 1980-08-18 | Continental Pharma | Derives de phenylethylamine, leur preparation et utilisation ainsi que composition contenant ces derives. |
DE3026534A1 (de) * | 1980-07-12 | 1982-03-18 | C.H. Boehringer Sohn, 6507 Ingelheim | 3,1-benzoxazin-2-one, ihre herstellung und verwendung |
US4460581A (en) * | 1982-10-12 | 1984-07-17 | Boehringer Ingelheim Kg | (1-Hydroxy-2-amino-alkyl)-substituted benzoxazinones and benzoxazolinones |
DE3325875A1 (de) * | 1983-07-18 | 1985-01-31 | Boehringer Ingelheim KG, 6507 Ingelheim | Neue 1-phenylimidazolidin-2-on-derivate, ihre herstellung und verwendung |
US4743613A (en) * | 1986-04-08 | 1988-05-10 | Smithkline Beckman Corporation | Ester prodrugs of dopamine-β-hydroxylase, inhibitors, composition containing them, and method of using them to inhibit dopamine-β-hydroxylase activity |
GB8609331D0 (en) * | 1986-04-16 | 1986-05-21 | Pfizer Ltd | Anti-arrythmia agents |
TW203049B (es) * | 1990-04-13 | 1993-04-01 | Yamanouchi Pharma Co Ltd | |
ZA967892B (en) * | 1995-09-21 | 1998-03-18 | Lilly Co Eli | Selective β3 adrenergic agonists. |
US5808080A (en) | 1996-09-05 | 1998-09-15 | Eli Lilly And Company | Selective β3 adrenergic agonists |
ES2171839T3 (es) | 1996-09-05 | 2002-09-16 | Lilly Co Eli | Analogos de carbazol como agonistas adrenergicos selectivos de beta3. |
CO5011072A1 (es) * | 1997-12-05 | 2001-02-28 | Lilly Co Eli | Etanolaminas pirazinil substituidas como agfonistas de los receptores |
DK1385515T3 (da) | 2001-04-18 | 2008-10-27 | Euro Celtique Sa | Spiropyrazole forbindelser |
SI1975164T1 (sl) * | 2001-04-18 | 2010-05-31 | Euro Celtique Sa | Oktahidrobenzimidazolonske spojine kot analgetiki |
DE60231257D1 (de) * | 2001-04-18 | 2009-04-02 | Euro Celtique Sa | 1-(4-piperidinyl)-1,3-dihydro-2h-indol-2-on derivate und verwandte verbindungen als nociceptin analoge und orl1 liganden zur behandlung von schmerz |
IL158486A0 (en) * | 2001-04-18 | 2004-05-12 | Euro Celtique Sa | Nociceptin analogs |
AU2002256282C1 (en) | 2001-04-18 | 2006-08-17 | Euroceltique S.A. | Spiroindene and spiroindane compounds |
US7056916B2 (en) * | 2002-11-15 | 2006-06-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Medicaments for the treatment of chronic obstructive pulmonary disease |
JP2006509790A (ja) * | 2002-11-27 | 2006-03-23 | アルテシアン セラピューティック,インコーポレイティド | 心不全の治療のための混合されたPDE阻害およびβアドレナリン拮抗薬活性または部分的作用薬活性を有する化合物 |
WO2004058726A2 (en) * | 2002-12-23 | 2004-07-15 | Artesian Therapeutics, Inc. | CARDIOTONIC COMPOUNDS WITH INHIBITORY ACTIVITY AGAINST β-ADRENERGIC RECEPTORS AND PHOSPHODIESTERASE |
DE102004001413A1 (de) * | 2004-01-09 | 2005-08-18 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 3-Hydroxymethyl-4-Hydroxy-Phenyl-Derivate zur Behandlung von chronisch obstruktiver Lungenerkrankung |
DE102004003428A1 (de) * | 2004-01-23 | 2005-08-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue langwirksame Beta-2-Agonisten, und deren Verwendung als Arzneimittel |
US20050272726A1 (en) * | 2004-04-22 | 2005-12-08 | Boehringer Ingelheim International Gmbh | Novel medicaments for the treatment of respiratory diseases |
DE102004021779A1 (de) * | 2004-04-30 | 2005-11-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
US7220742B2 (en) | 2004-05-14 | 2007-05-22 | Boehringer Ingelheim International Gmbh | Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments |
US20050255050A1 (en) * | 2004-05-14 | 2005-11-17 | Boehringer Ingelheim International Gmbh | Powder formulations for inhalation, comprising enantiomerically pure beta agonists |
US20050256115A1 (en) * | 2004-05-14 | 2005-11-17 | Boehringer Ingelheim International Gmbh | Aerosol formulation for the inhalation of beta-agonists |
DE102004045648A1 (de) * | 2004-09-21 | 2006-03-23 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Betamimetika zur Behandlung von Atemwegserkrankungen |
US20080090827A1 (en) * | 2004-11-30 | 2008-04-17 | Artesian Therapeutics, Inc. | Compounds With Mixed Pde-Inhibitory and Beta-Adrenergic Antagonist or Partial Agonist Activity For Treatment of Heart Failure |
EP1833480A2 (en) * | 2004-11-30 | 2007-09-19 | Artesian Therapeutics, Inc. | Cardiotonic compounds with inhibitory activity against beta-adrenergic receptors and phosphodiesterase |
DE102005007654A1 (de) * | 2005-02-19 | 2006-08-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue langwirksame Betamimetika zur Behandlung von Atemwegserkrankungen |
DE102005030733A1 (de) * | 2005-07-01 | 2007-01-04 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen enthaltend langwirksame Beta-2-Agonisten und wenigstens einen weiteren Wirkstoff |
BRPI0614410A2 (pt) * | 2005-08-15 | 2011-03-29 | Boehringer Ingelheim Int | processo para preparação de betamiméticos |
DE102005052102A1 (de) * | 2005-10-28 | 2007-05-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
DE102005052101A1 (de) * | 2005-10-28 | 2007-05-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
DE102005052127A1 (de) * | 2005-10-28 | 2007-05-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue indol-haltige Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
EP1986644A1 (de) * | 2006-02-16 | 2008-11-05 | Boehringer Ingelheim International GmbH | Arzneimittelkombinationen zur behandlung von atemwegserkrankungen |
PE20080142A1 (es) * | 2006-03-15 | 2008-04-14 | Boehringer Ingelheim Int | Beta-agonistas enantiomericamente puros y sus procedimientos de preparacion |
CA2660186A1 (en) | 2006-08-07 | 2008-02-14 | Boehringer Ingelheim International Gmbh | Pharmaceutical combinations for the treatment of respiratory diseases |
US9604926B2 (en) | 2007-08-16 | 2017-03-28 | The University Of Mississippi | Highly selective sigma receptor radioligands |
WO2009026227A2 (en) * | 2007-08-16 | 2009-02-26 | The University Of Mississippi | Highly selective sigma receptor ligands |
US8686008B2 (en) * | 2007-08-16 | 2014-04-01 | The University Of Mississippi | Highly selective sigma receptor ligands |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA631296A (en) * | 1961-11-21 | L. Clark Robert | Substituted benzimidazolones | |
CH149009A (de) * | 1929-08-10 | 1931-08-15 | Chem Ind Basel | Verfahren zur Darstellung einer N-substituierten Verbindung der Pyridonreihe. |
US2857394A (en) * | 1957-05-10 | 1958-10-21 | Ciba Pharm Prod Inc | Heterocyclic compounds |
NL284529A (es) * | 1961-10-24 | |||
FR1516714A (fr) * | 1962-11-07 | 1968-02-05 | Bayer Ag | Procédé de préparation de dérivés de l'imidazolidine |
FR1384708A (fr) * | 1963-11-21 | 1965-01-08 | Thomson Houston Comp Francaise | Perfectionnements aux dispositifs de mise en place d'objets |
BE659364A (es) * | 1964-02-05 | |||
US3355457A (en) * | 1965-05-21 | 1967-11-28 | American Cyanamid Co | Substituted 2-imidazolinones |
FR1573739A (es) * | 1968-07-26 | 1969-07-04 | ||
US3984405A (en) * | 1971-06-28 | 1976-10-05 | E. R. Squibb & Sons, Inc. | Anti-inflammatory agents |
BE787103A (fr) * | 1971-08-04 | 1973-02-02 | Pfizer | Nouveaux derives de propanolamine et composition pharmaceutiqueles contenant |
FR2168140A1 (en) * | 1972-01-17 | 1973-08-31 | Bellon Labor Sa Roger | Dihydro-benzoxazine derivs - antidepressants |
US3925383A (en) * | 1972-12-08 | 1975-12-09 | Janssen Pharmaceutica Nv | Bicyclic imidazoles and pyrimidines |
US3994901A (en) * | 1974-06-13 | 1976-11-30 | Otsuka Pharmaceutical Company Limited | 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-hydroxy-3,4-dihydrocarbostyril derivatives |
US4081447A (en) * | 1975-04-09 | 1978-03-28 | Abbott Laboratories | 5-[2-Hydroxy-3-(3,4-dimethoxy phenethylamino)]-propoxy-3,4-dihydro carbostyril and pharmaceutically acceptable salts thereof |
DE2609645A1 (de) * | 1976-03-09 | 1977-09-15 | Boehringer Sohn Ingelheim | Aminoalkylheterocyclen |
-
1976
- 1976-03-09 DE DE19762609645 patent/DE2609645A1/de not_active Withdrawn
-
1977
- 1977-02-22 SU SU772453505A patent/SU698530A3/ru active
- 1977-02-23 FI FI770586A patent/FI69070C/fi not_active IP Right Cessation
- 1977-02-24 AT AT122377A patent/AT360542B/de not_active IP Right Cessation
- 1977-03-01 RO RO77101591A patent/RO79706A/ro unknown
- 1977-03-01 RO RO7789565A patent/RO70569A/ro unknown
- 1977-03-01 RO RO7796539A patent/RO76589A/ro unknown
- 1977-03-02 US US05/773,394 patent/US4154829A/en not_active Expired - Lifetime
- 1977-03-03 MX MX775497U patent/MX4878E/es unknown
- 1977-03-04 CS CS775352A patent/CS220320B2/cs unknown
- 1977-03-04 CS CS771476A patent/CS209435B2/cs unknown
- 1977-03-07 NL NL7702403A patent/NL7702403A/xx not_active Application Discontinuation
- 1977-03-07 BG BG035601A patent/BG27743A3/xx unknown
- 1977-03-07 BG BG036628A patent/BG28051A4/xx unknown
- 1977-03-07 DD DD7700197718A patent/DD130037A5/xx unknown
- 1977-03-07 CH CH281977A patent/CH630358A5/de not_active IP Right Cessation
- 1977-03-07 BG BG036629A patent/BG28052A4/xx unknown
- 1977-03-07 LU LU76898A patent/LU76898A1/xx unknown
- 1977-03-08 HU HU77BO1653A patent/HU177953B/hu unknown
- 1977-03-08 IE IE507/77A patent/IE45300B1/en unknown
- 1977-03-08 SE SE7702609A patent/SE435059B/xx not_active IP Right Cessation
- 1977-03-08 NZ NZ183536A patent/NZ183536A/xx unknown
- 1977-03-08 PL PL1977215210A patent/PL112937B1/pl unknown
- 1977-03-08 PT PT66282A patent/PT66282B/pt unknown
- 1977-03-08 YU YU00623/77A patent/YU62377A/xx unknown
- 1977-03-08 JP JP2532377A patent/JPS52108970A/ja active Pending
- 1977-03-08 DK DK102177A patent/DK102177A/da not_active Application Discontinuation
- 1977-03-08 BE BE175593A patent/BE852223A/xx not_active IP Right Cessation
- 1977-03-08 CA CA273,388A patent/CA1086317A/en not_active Expired
- 1977-03-08 NO NO770804A patent/NO147950C/no unknown
- 1977-03-08 ZA ZA00771412A patent/ZA771412B/xx unknown
- 1977-03-08 PL PL1977196505A patent/PL111240B1/pl unknown
- 1977-03-08 IL IL51627A patent/IL51627A/xx unknown
- 1977-03-08 GR GR52928A patent/GR64553B/el unknown
- 1977-03-08 AU AU23009/77A patent/AU515953B2/en not_active Expired
- 1977-03-08 ES ES456622A patent/ES456622A1/es not_active Expired
- 1977-03-09 PH PH19550A patent/PH16110A/en unknown
- 1977-03-09 GB GB9952/77A patent/GB1571231A/en not_active Expired
- 1977-03-09 FR FR7707018A patent/FR2343731A1/fr active Granted
- 1977-11-16 SU SU772542149A patent/SU685149A3/ru active
- 1977-11-16 SU SU772541704A patent/SU676163A3/ru active
- 1977-11-16 SU SU772543651A patent/SU683616A3/ru active
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1978
- 1978-02-01 FR FR7802775A patent/FR2372810A1/fr active Granted
- 1978-02-03 ES ES466606A patent/ES466606A1/es not_active Expired
- 1978-02-03 ES ES466605A patent/ES466605A1/es not_active Expired
- 1978-02-03 ES ES466598A patent/ES466598A1/es not_active Expired
- 1978-02-03 ES ES466602A patent/ES466602A1/es not_active Expired
- 1978-02-03 ES ES466604A patent/ES466604A1/es not_active Expired
- 1978-02-03 ES ES466603A patent/ES466603A1/es not_active Expired
- 1978-02-03 ES ES466601A patent/ES466601A1/es not_active Expired
- 1978-02-03 ES ES466600A patent/ES466600A1/es not_active Expired
- 1978-02-03 ES ES466599A patent/ES466599A1/es not_active Expired
- 1978-06-14 BG BG036630A patent/BG28053A4/xx unknown
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1979
- 1979-04-03 US US06/026,608 patent/US4215119A/en not_active Expired - Lifetime
- 1979-12-13 US US06/102,904 patent/US4271158A/en not_active Expired - Lifetime
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1980
- 1980-07-11 PH PH24278A patent/PH16149A/en unknown
- 1980-12-22 US US06/218,786 patent/US4363814A/en not_active Expired - Fee Related
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1981
- 1981-01-23 PH PH25130A patent/PH17635A/en unknown
- 1981-04-30 CH CH285181A patent/CH630364A5/de not_active IP Right Cessation
- 1981-04-30 CH CH284681A patent/CH630359A5/de not_active IP Right Cessation
- 1981-04-30 CH CH284981A patent/CH630362A5/de not_active IP Right Cessation
- 1981-04-30 CH CH284881A patent/CH630361A5/de not_active IP Right Cessation
- 1981-04-30 CH CH284781A patent/CH630360A5/de not_active IP Right Cessation
- 1981-04-30 CH CH285081A patent/CH630363A5/de not_active IP Right Cessation
- 1981-04-30 CH CH285281A patent/CH630365A5/de not_active IP Right Cessation
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1983
- 1983-09-01 SG SG555/83A patent/SG55583G/en unknown
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1984
- 1984-02-16 HK HK128/84A patent/HK12884A/xx unknown
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1985
- 1985-06-12 JP JP60126401A patent/JPS6172A/ja active Pending
- 1985-12-30 MY MY79/85A patent/MY8500079A/xx unknown
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FD1A | Patent lapsed |
Effective date: 20000103 |