FR14C0066I2 - 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles - Google Patents
2,3-dihydro-6-nitroimidazo[2,1-b]oxazolesInfo
- Publication number
- FR14C0066I2 FR14C0066I2 FR14C0066C FR14C0066C FR14C0066I2 FR 14C0066 I2 FR14C0066 I2 FR 14C0066I2 FR 14C0066 C FR14C0066 C FR 14C0066C FR 14C0066 C FR14C0066 C FR 14C0066C FR 14C0066 I2 FR14C0066 I2 FR 14C0066I2
- Authority
- FR
- France
- Prior art keywords
- nitroimidazo
- oxazoles
- dihydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- ZCQWOFVYLHDMMC-UHFFFAOYSA-N Oxazole Chemical compound C1=COC=N1 ZCQWOFVYLHDMMC-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/20—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2002298259 | 2002-10-11 | ||
PCT/JP2003/013070 WO2004033463A1 (ja) | 2002-10-11 | 2003-10-10 | 2,3−ジヒドロ−6−ニトロイミダゾ[2,1−b]オキサゾール化合物 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR14C0066I1 FR14C0066I1 (is) | 2014-10-17 |
FR14C0066I2 true FR14C0066I2 (fr) | 2015-05-22 |
Family
ID=32089299
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR14C0066C Active FR14C0066I2 (fr) | 2002-10-11 | 2014-09-11 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles |
Country Status (27)
Country | Link |
---|---|
US (1) | US7262212B2 (is) |
EP (2) | EP2570418A3 (is) |
JP (1) | JP4186065B2 (is) |
KR (1) | KR100723847B1 (is) |
CN (4) | CN100366624C (is) |
AR (4) | AR041198A1 (is) |
AU (1) | AU2003272979B2 (is) |
BE (1) | BE2014C053I2 (is) |
BR (1) | BRPI0314344B8 (is) |
CA (1) | CA2497569C (is) |
CY (2) | CY1113578T1 (is) |
DK (1) | DK1555267T3 (is) |
ES (1) | ES2400179T3 (is) |
FR (1) | FR14C0066I2 (is) |
HK (2) | HK1085463A1 (is) |
HU (1) | HUS1400046I1 (is) |
LU (1) | LU92517I2 (is) |
MX (1) | MXPA05003674A (is) |
MY (1) | MY139244A (is) |
PL (3) | PL404913A1 (is) |
PT (1) | PT1555267E (is) |
RU (1) | RU2326121C3 (is) |
SI (1) | SI1555267T1 (is) |
TW (1) | TWI347946B (is) |
UA (1) | UA83200C2 (is) |
WO (1) | WO2004033463A1 (is) |
ZA (1) | ZA200501033B (is) |
Families Citing this family (81)
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AU2002217999A1 (en) | 2000-11-01 | 2002-05-15 | Cor Therapeutics, Inc. | Process for the production of 4-quinazolinylpiperazin-1-carboxylic acid phenylamides |
RU2324682C2 (ru) * | 2002-10-15 | 2008-05-20 | Оцука Фармасьютикал Ко., Лтд. | Производное 1-замещенного 4-нитроимидазола и способ его получения |
KR100851802B1 (ko) * | 2003-10-31 | 2008-08-13 | 오쓰까 세이야꾸 가부시키가이샤 | 결핵의 치료를 위한2,3-디히드로-6-니트로이미다조[2,1-b]옥사졸 화합물 |
JP4761756B2 (ja) * | 2003-10-31 | 2011-08-31 | 大塚製薬株式会社 | 2,3−ジヒドロイミダゾ[2,1−b]オキサゾ−ル化合物 |
TWI300409B (en) | 2004-02-18 | 2008-09-01 | Otsuka Pharma Co Ltd | Method for producing 4-nitroimidazole compound |
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JP4789966B2 (ja) * | 2004-04-09 | 2011-10-12 | 大塚製薬株式会社 | 医薬組成物 |
JP4787529B2 (ja) * | 2004-04-09 | 2011-10-05 | 大塚製薬株式会社 | 医薬組成物 |
US7408066B2 (en) * | 2005-06-20 | 2008-08-05 | Schering Corproation | Carbon-linked substituted piperidines and derivatives thereof useful as histamine H3 antagonists |
MX2008001210A (es) * | 2005-07-28 | 2008-03-24 | Otsuka Pharma Co Ltd | Composicion farmaceutica que comprende derivados de 2,3-dihidro-6-nitroimidazo{2,1-b]oxazol. |
TW201233389A (en) * | 2005-10-05 | 2012-08-16 | Otsuka Pharma Co Ltd | Antituberculous therapeutic drugs and kit containing the same |
JP5105818B2 (ja) * | 2005-10-05 | 2012-12-26 | 大塚製薬株式会社 | 医薬組成物 |
CN102936221B (zh) * | 2005-10-06 | 2014-09-10 | 日本曹达株式会社 | 桥联环状胺化合物以及有害生物防除剂 |
TW200800268A (en) * | 2005-11-04 | 2008-01-01 | Otsuka Pharma Co Ltd | Medicinal composition showing improved drug absorbability |
AU2006333522A1 (en) * | 2005-12-21 | 2007-07-12 | Decode Genetics, Ehf. | Biaryl nitrogen heterocycle inhibitors of LTA4H for treating inflammation |
JP2009526773A (ja) * | 2006-02-13 | 2009-07-23 | ラボラトワール セローノ ソシエテ アノニム | 細菌感染症治療のためのスルホンアミド誘導体 |
JP2007297305A (ja) * | 2006-04-28 | 2007-11-15 | Daiso Co Ltd | N−(2,3−エポキシ−2−メチルプロピル)フタルイミドの製造法 |
EP2125750B1 (en) * | 2007-02-26 | 2014-05-21 | Vitae Pharmaceuticals, Inc. | Cyclic urea and carbamate inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
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CL2008002199A1 (es) * | 2007-07-26 | 2009-10-23 | Vitae Pharmaceuticals Inc | Compuestos derivados de 1,3-oxazin-2-ona; composicion farmaceutica que comprende a dichos compuestos; y uso para tratar una enfermedad asociada con la actividad de la 11beta-hidroxiesteroide deshidrogenasa tipo 1 (11beta-hsd1) tales como dislipidemia, hiperlipidemia, hipertension, obesidad y enfermedad cardiovascular, entre otras. |
WO2009021965A2 (en) * | 2007-08-15 | 2009-02-19 | Glaxo Group Limited | Substituted quinoline derivatives as h1 receptor antagonists |
US20100222349A1 (en) * | 2007-10-16 | 2010-09-02 | Glaxo Group Limited | Quinoline derivatives used to treat inflammatory and allergic diseases |
AR069207A1 (es) * | 2007-11-07 | 2010-01-06 | Vitae Pharmaceuticals Inc | Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1 |
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CN103524492A (zh) * | 2013-10-23 | 2014-01-22 | 中国药科大学 | 侧链含硝基咪唑基团取代的喹诺酮类化合物、其制备及用途 |
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CN105732659B (zh) * | 2014-12-12 | 2019-07-16 | 上海阳帆医药科技有限公司 | 硝基咪唑类化合物及其制备方法和在制药中的用途 |
CN107207532B (zh) * | 2015-01-29 | 2019-07-30 | 南京明德新药研发股份有限公司 | 抗肺结核病的硝基咪唑衍生物 |
LT3275862T (lt) | 2015-03-27 | 2020-09-25 | Otsuka Pharmaceutical Co., Ltd. | 1-(4-hidroksifenil)-4-(4-trifluormetoksifenoksi)piperidino arba jo druskos gamybos būdas |
CN106317072B (zh) * | 2015-06-17 | 2020-03-17 | 盟科医药技术(上海)有限公司 | 用于分枝杆菌感染治疗的杂环化合物及其应用 |
US10851079B2 (en) | 2016-02-26 | 2020-12-01 | Otsuka Pharmaceutical Co., Ltd. | Piperidine derivative |
CN105859628B (zh) * | 2016-04-19 | 2018-08-07 | 清远职业技术学院 | 一种抗菌化合物对n咪唑苯甲醛缩邻甲苯胺希夫碱及其制备方法和应用 |
JP2019521175A (ja) * | 2016-07-22 | 2019-07-25 | メッドシャイン ディスカバリー インコーポレイテッド | ニトロイミダゾール系化合物の結晶形、塩形およびその製造方法 |
SG11202000988RA (en) * | 2017-08-16 | 2020-03-30 | Glaxosmithkline Ip Dev Ltd | Novel compounds |
KR20210019056A (ko) | 2018-06-11 | 2021-02-19 | 오츠카 세이야쿠 가부시키가이샤 | 델라마니드 함유 조성물 |
CN109705022A (zh) * | 2018-12-28 | 2019-05-03 | 上海彩迩文生化科技有限公司 | 一种芳香胺中间体的制备方法 |
CN112300192B (zh) * | 2019-08-02 | 2023-08-11 | 南京长澳医药科技有限公司 | 硝基咪唑类化合物及其制备方法和用途 |
CN110483549B (zh) * | 2019-08-30 | 2021-03-05 | 沈阳药科大学 | 一种硝基咪唑吡喃类抗结核药物的制备方法 |
CN110615800A (zh) * | 2019-10-16 | 2019-12-27 | 李丽丽 | 硝基咪唑类化合物及其制备方法和用途 |
CN112156088B (zh) * | 2020-10-30 | 2021-08-31 | 健民药业集团股份有限公司 | 一种化合物在制备结核分枝杆菌抑制剂中的用途 |
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CN115368252B (zh) * | 2022-09-19 | 2024-01-12 | 西北农林科技大学 | 一种4-胺基酚类衍生物及应用 |
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---|---|---|---|---|
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2003
- 2003-10-09 TW TW092128165A patent/TWI347946B/zh not_active IP Right Cessation
- 2003-10-09 AR ARP030103673A patent/AR041198A1/es active IP Right Grant
- 2003-10-10 MX MXPA05003674A patent/MXPA05003674A/es active IP Right Grant
- 2003-10-10 PL PL404913A patent/PL404913A1/pl unknown
- 2003-10-10 CN CNB2003801017508A patent/CN100366624C/zh not_active Expired - Lifetime
- 2003-10-10 SI SI200332254T patent/SI1555267T1/sl unknown
- 2003-10-10 BR BRPI0314344A patent/BRPI0314344B8/pt not_active IP Right Cessation
- 2003-10-10 ES ES03754085T patent/ES2400179T3/es not_active Expired - Lifetime
- 2003-10-10 RU RU2005114017A patent/RU2326121C3/ru active Protection Beyond IP Right Term
- 2003-10-10 DK DK03754085.3T patent/DK1555267T3/da active
- 2003-10-10 AU AU2003272979A patent/AU2003272979B2/en not_active Expired
- 2003-10-10 KR KR1020057004567A patent/KR100723847B1/ko active Protection Beyond IP Right Term
- 2003-10-10 EP EP12193820.3A patent/EP2570418A3/en not_active Withdrawn
- 2003-10-10 CA CA2497569A patent/CA2497569C/en not_active Expired - Lifetime
- 2003-10-10 PL PL376157A patent/PL217919B1/pl unknown
- 2003-10-10 UA UAA200504391A patent/UA83200C2/ru unknown
- 2003-10-10 PT PT37540853T patent/PT1555267E/pt unknown
- 2003-10-10 CN CN201110416170.4A patent/CN102532162B/zh not_active Expired - Lifetime
- 2003-10-10 CN CNA2007100040371A patent/CN101255170A/zh active Pending
- 2003-10-10 CN CNA2007100040367A patent/CN101172981A/zh active Pending
- 2003-10-10 PL PL409525A patent/PL409525A1/pl unknown
- 2003-10-10 US US10/530,429 patent/US7262212B2/en not_active Expired - Lifetime
- 2003-10-10 WO PCT/JP2003/013070 patent/WO2004033463A1/ja active Application Filing
- 2003-10-10 MY MYPI20033866A patent/MY139244A/en unknown
- 2003-10-10 EP EP03754085A patent/EP1555267B1/en not_active Expired - Lifetime
- 2003-10-14 JP JP2003353868A patent/JP4186065B2/ja not_active Expired - Lifetime
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2005
- 2005-02-03 ZA ZA200501033A patent/ZA200501033B/en unknown
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2006
- 2006-02-03 HK HK06101486A patent/HK1085463A1/xx not_active IP Right Cessation
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2012
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- 2012-11-21 HK HK12111863.7A patent/HK1171018A1/xx not_active IP Right Cessation
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2013
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- 2013-07-15 AR ARP130102514 patent/AR091771A2/es not_active Application Discontinuation
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2014
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- 2014-08-14 HU HUS1400046C patent/HUS1400046I1/hu unknown
- 2014-09-09 BE BE2014C053C patent/BE2014C053I2/fr unknown
- 2014-09-11 FR FR14C0066C patent/FR14C0066I2/fr active Active
- 2014-09-24 CY CY2014041C patent/CY2014041I2/el unknown
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