FR07C0071I1 - - Google Patents

Info

Publication number
FR07C0071I1
FR07C0071I1 FR07C0071C FR07C0071I1 FR 07C0071 I1 FR07C0071 I1 FR 07C0071I1 FR 07C0071 C FR07C0071 C FR 07C0071C FR 07C0071 I1 FR07C0071 I1 FR 07C0071I1
Authority
FR
France
Prior art keywords
bacteria
infected cells
cells
attenuated
cultivate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
Other languages
English (en)
French (fr)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27041284&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR07C0071(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/465,337 external-priority patent/US5714375A/en
Application filed filed Critical
Publication of FR07C0071I1 publication Critical patent/FR07C0071I1/fr
Application granted granted Critical
Publication of FR07C0071I2 publication Critical patent/FR07C0071I2/fr
Active legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/105Delta proteobacteriales, e.g. Lawsonia; Epsilon proteobacteriales, e.g. campylobacter, helicobacter
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/554Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being a biological cell or cell fragment, e.g. bacteria, yeast cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90Isomerases (5.)
    • C12N9/92Glucose isomerase (5.3.1.5; 5.3.1.9; 5.3.1.18)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/56922Campylobacter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00Immunoassays for the detection of microorganisms
    • G01N2469/20Detection of antibodies in sample from host which are directed against antigens from microorganisms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/825Bacterial vaccine for porcine species, e.g. swine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
FR07C0071C 1995-06-05 2007-12-21 Culture de lawsonia intracellularis, vaccins anti-lawsonia intracellularis et agents de diagnostic Active FR07C0071I2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/465,337 US5714375A (en) 1995-06-05 1995-06-05 Ileal symbiont intracellularis propagation in suspended host cells
US08/658,194 US5885823A (en) 1995-06-05 1996-06-04 Lawsonia intracellularis cultivation, anti-Lawsonia intracellularis vaccines and diagnostic agents
EP03022895.1A EP1403643B2 (en) 1995-06-05 1996-06-05 Lawsonia intracellularis cultivation, anti-lawsonia intracelluaris vaccines and diagnostic agents
EP96921391.7A EP0843818B2 (en) 1995-06-05 1996-06-05 Lawsonia intracellularis cultivation, anti-lawsonia intracellularis vaccines and diagnostic agents

Publications (2)

Publication Number Publication Date
FR07C0071I1 true FR07C0071I1 (pl) 2008-01-02
FR07C0071I2 FR07C0071I2 (fr) 2010-12-31

Family

ID=27041284

Family Applications (1)

Application Number Title Priority Date Filing Date
FR07C0071C Active FR07C0071I2 (fr) 1995-06-05 2007-12-21 Culture de lawsonia intracellularis, vaccins anti-lawsonia intracellularis et agents de diagnostic

Country Status (24)

Country Link
US (1) US5885823A (pl)
EP (5) EP1645567B2 (pl)
JP (4) JP3765834B2 (pl)
KR (4) KR100758614B1 (pl)
AT (3) ATE373015T1 (pl)
AU (1) AU717045B2 (pl)
BG (1) BG64292B1 (pl)
BR (2) BRPI9612938B8 (pl)
CA (1) CA2222643C (pl)
CZ (1) CZ295933B6 (pl)
DE (5) DE69638016D1 (pl)
DK (3) DK1645567T4 (pl)
ES (3) ES2332587T3 (pl)
FR (1) FR07C0071I2 (pl)
HK (1) HK1010911A1 (pl)
HU (1) HU230199B1 (pl)
LU (1) LU91405I2 (pl)
NL (1) NL300331I2 (pl)
NZ (1) NZ319994A (pl)
PL (6) PL187849B1 (pl)
PT (3) PT843818E (pl)
RO (1) RO118885B1 (pl)
RU (2) RU2265849C2 (pl)
WO (1) WO1996039629A1 (pl)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000502054A (ja) * 1995-11-30 2000-02-22 アグリカルチャー ビクトリア サービシーズ ピーティーワイ.エルティーディー. 治療用および診断用の組成物
FR2772047B1 (fr) * 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
US7052697B1 (en) * 1999-05-13 2006-05-30 Agriculture Victoria Services Pty Ltd Lawsonia derived gene and related OmpH polypeptides, peptides and proteins and their uses
WO2000069906A1 (en) * 1999-05-13 2000-11-23 Pfizer Products Inc Lawsonia derived gene and related hemolysin polypeptides, peptides and proteins and their uses
US7029683B1 (en) 1999-05-13 2006-04-18 Pfizer Products, Inc. Lawsonia derived gene and related hemolysin polypeptides, peptides and proteins and their uses
AU771376B2 (en) * 1999-05-13 2004-03-18 Agriculture Victoria Services Pty Ltd Lawsonia derived gene and related FlgE polypeptides, peptides and proteins and their uses
JP2003501013A (ja) * 1999-05-13 2003-01-14 ファイザー プロダクツ インコーポレーティッド ローソニア由来の遺伝子及び関連SodCポリペプチド、ぺプチド及びタンパク質並びにそれらの使用
WO2000069905A1 (en) * 1999-05-13 2000-11-23 Australian Pork Limited LAWSONIA DERIVED GENE AND RELATED OmpH POLYPEPTIDES, PEPTIDES AND PROTEINS AND THEIR USES
US6605696B1 (en) * 1999-10-22 2003-08-12 Pfizer, Inc. Lawsonia intracellularis proteins, and related methods and materials
JP2004529854A (ja) * 2000-09-29 2004-09-30 アリゾナ・ボード・オブ・リージエンツ・オン・ビハーフ・オブ・ザ・ユニバーシテイー・オブ・アリゾナ 増殖性回腸炎のための改善されたワクチン及びその作製と使用の方法
AUPR138100A0 (en) 2000-11-10 2000-12-07 Agriculture Victoria Services Pty Ltd Novel therapeutic compositions for treating infection by lawsonia spp
EP1332154A4 (en) * 2000-11-10 2005-05-11 Agriculture Victoria Serv Pty NEW THERAPEUTIC COMPOSITIONS FOR TREATING LAWSONIA SPP INFECTION
DK1219711T3 (da) * 2000-12-20 2006-09-25 Intervet Int Bv Lawsonia Intracellularis vaccine
US20030087421A1 (en) * 2001-07-11 2003-05-08 Gebhart Connie J Lawsonia intracellularis
WO2004033631A2 (en) * 2002-10-04 2004-04-22 Regents Of The University Of Minnesota Nucleic acid and polypeptide sequences from lawsonia intracellularis and methods of using
JP2006528882A (ja) * 2003-07-25 2006-12-28 ベーリンガー インゲルハイム フェトメディカ インコーポレイテッド 欧州起源のローソニア・イントラセルラリス並びにそのワクチン、診断薬及び使用方法
DK1664100T3 (da) 2003-09-12 2010-04-06 Intervet Int Bv Vaccine med underenhed af Lawsonia intracellularis
KR20060112674A (ko) * 2003-12-09 2006-11-01 인터벳 인터내셔널 비.브이. 로소니아 인트라셀룰라리스 26 kd 서브유닛 백신
KR20060134054A (ko) * 2004-01-22 2006-12-27 인터벳 인터내셔널 비.브이. 로소니아 인트라셀룰라리스 서브유닛 백신
MY146476A (en) * 2004-06-24 2012-08-15 Boehringer Ingelheim Vetmed Method of diagnosing lawsonia intracellularis
EP1609870A1 (en) * 2004-06-24 2005-12-28 Boehringer Ingelheim Vetmedica Gmbh Method of diagnosing lawsonia intracellularis
US20060021536A1 (en) * 2004-07-30 2006-02-02 Limin Song Method for creating an absorbent article exhibiting a harmonic color scheme
KR100621882B1 (ko) * 2004-09-30 2006-09-19 건국대학교 산학협력단 돼지 증식성 회장염 감염돈에서 로소니아인트라셀룰라리스 균을 분리하는 방법
WO2006056853A1 (en) * 2004-11-24 2006-06-01 Pharmacia & Upjohn Company Llc Methods for cultivating lawsonia intracellularis
US20070212373A1 (en) * 2004-12-08 2007-09-13 Akzo Nobel N.V. Lawsonia Intracellularis 26 Kd Subunit Vaccine
US7833707B2 (en) * 2004-12-30 2010-11-16 Boehringer Ingelheim Vetmedica, Inc. Methods of overexpression and recovery of porcine circovirus type 2 ORF2
UA95602C2 (ru) 2004-12-30 2011-08-25 Берингер Ингельхейм Ветмедика, Инк. Иммуногенная композиция цвс2 и способы приготовления такой композиции
US7700285B1 (en) 2005-12-29 2010-04-20 Boehringer Ingelheim Vetmedica, Inc. PCV2 immunogenic compositions and methods of producing such compositions
US8834891B2 (en) 2005-03-14 2014-09-16 Boehringer Ingelheim Vetmedica, Inc. Immunogenic compositions comprising Lawsonia intracellularis
US8398994B2 (en) * 2005-07-15 2013-03-19 Boehringer Ingelheim Vetmedica, Inc. Lawsonia vaccine and methods of use thereof
PT2371383E (pt) * 2005-12-29 2015-11-24 Boehringer Ingelheim Vetmed Utilização de uma composição imunogénica de pcv2 para atenuar os sintomas clínicos em porcos
EP3868400A1 (en) 2005-12-29 2021-08-25 Boehringer Ingelheim Animal Health USA Inc. Multivalent pcv2 immunogenic compositions and methods of producing such compositions
US8470336B2 (en) * 2006-05-25 2013-06-25 Boehringer Ingelheim Vetmedica, Inc. Vaccination of young animals against Lawsonia intracellularis infections
US20080241190A1 (en) * 2006-11-13 2008-10-02 Boehringer Ingelheim Vetmedica, Inc. Vaccination of horses against lawsonia intracellularis
EP2101815A4 (en) 2006-12-11 2010-10-06 Boehringer Ingelheim Vetmed EFFICIENT PROCESS FOR THE TREATMENT OF PORCINE CIRCOVIRUS AND LAWSONIA INTRACELLULARIS INFECTIONS
US8865183B2 (en) * 2006-12-15 2014-10-21 Boehringer Ingelheim Vetmedica, Inc. Treatment of pigs with PCV2 antigent
EP1941903A1 (en) 2007-01-03 2008-07-09 Boehringer Ingelheim Vetmedica Gmbh Prophylaxis and treatment of PRDC
EP1958644A1 (en) 2007-02-13 2008-08-20 Boehringer Ingelheim Vetmedica Gmbh Prevention and treatment of sub-clinical pcvd
US7829274B2 (en) * 2007-09-04 2010-11-09 Boehringer Ingelheim Vetmedica, Inc. Reduction of concomitant infections in pigs by the use of PCV2 antigen
EP2200643B1 (en) 2007-09-17 2013-09-04 Boehringer Ingelheim Vetmedica, Inc. A live lawsonia intracellularis vaccine administered in combination with an antibiotic for use in the treatment of lawsonia intracellularis infections in pigs
EP2205718A1 (en) * 2007-10-12 2010-07-14 Pfizer Inc. Methods of culturing lawsonia intracellularis
BRPI0821456A2 (pt) * 2007-12-31 2015-06-16 Boehring Ingelheim Vetmedica Inc Partícula similar à pcv2 orf2 com inserção de aminoácido estranho
EP2242511A4 (en) 2008-01-23 2012-10-24 Boehringer Ingelheim Vetmed IMMUNOGENIC COMPOSITIONS OF MYCOPLASMA HYOPNEUMONIAE PCV2, AND METHODS FOR PRODUCING SUCH COMPOSITIONS
US20110033495A1 (en) * 2008-02-15 2011-02-10 Boehringer Ingelheim Vetmedica, Inc. Methods and compositions for reducing the impact of enteric diseases
TWI551295B (zh) 2008-04-18 2016-10-01 英特威特國際股份有限公司 防備胞內勞森菌(Lawsonia intracellularis)用疫苗
TWI449533B (zh) 2008-04-18 2014-08-21 Intervet Int Bv 防備胞內勞森菌(Lawsonia intracellularis)、豬肺炎黴漿菌(Mycoplasma hyopneumoniae)及豬環狀病毒(Porcine circo virus)用疫苗
EP2318041B1 (en) * 2008-07-22 2015-02-25 Intervet International BV Lawsonia intracellularis bacterium of a novel serotype, vaccine based on that bacterium, antibodies suitable for diagnosing the novel lawsonia intracellularis serotype and hybridomas for producing the said antibodies
US8142760B2 (en) * 2008-09-05 2012-03-27 Nathan Len Winkelman Vaccination for Lawsonia intracellularis
WO2011006880A1 (en) * 2009-07-14 2011-01-20 Intervet International B.V. Lawsonia intracellularis propagation
AR078253A1 (es) * 2009-09-02 2011-10-26 Boehringer Ingelheim Vetmed Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad
ES2606131T3 (es) 2009-11-09 2017-03-22 Intervet International B.V. Método para cultivar bacterias Lawsonia intracellularis en células McCoy infectadas de forma persistente
CN104968365B (zh) * 2012-12-28 2018-04-03 勃林格殷格翰动物保健有限公司 支原体疫苗的制备方法
KR102319843B1 (ko) 2013-09-25 2021-10-29 조에티스 서비시즈 엘엘씨 Pcv2b 분지형 백신 조성물 및 사용 방법
KR20220083861A (ko) 2013-10-02 2022-06-20 베링거 인겔하임 애니멀 헬스 유에스에이 인크. Pcv2 orf2 단백질 변이체 및 이로 이루어진 바이러스 유사 입자
WO2016124620A1 (en) 2015-02-04 2016-08-11 Intervet International B.V. A vaccine for use against subclinical lawsonia infection in a pig
JP2018504423A (ja) * 2015-02-04 2018-02-15 インターベット インターナショナル ベー. フェー. 豚における無症候性ローソニア感染症に対する使用のためのワクチン
KR20180062468A (ko) * 2016-11-18 2018-06-11 녹십자수의약품(주) 신규한 로소니아 인트라셀룰라리스 균주 및 이의 용도
KR20200127003A (ko) * 2018-02-28 2020-11-09 베링거잉겔하임베트메디카게엠베하 동물에서 스카톨 및/또는 인돌을 감소시키는 방법
JP2023535066A (ja) 2020-07-24 2023-08-15 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド 組合せブタワクチン
AU2022375120A1 (en) 2021-11-01 2024-04-11 Boehringer Ingelheim Vetmedica Gmbh Immunogenic gel compositions
WO2024068637A1 (en) 2022-09-27 2024-04-04 Intervet International B.V. A method of culturing lawsonia intracellularis bacteria

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4132597A (en) * 1976-06-09 1979-01-02 Ab Medipharm Method for cultivation of bacteria
US4237218A (en) * 1979-02-09 1980-12-02 Bio-Rad Laboratories, Inc. Micro-carrier cell culture
JPS5991879A (ja) * 1982-11-16 1984-05-26 Hideaki Yamada シユ−ドモナス属細菌の培養法
DK594084A (da) * 1984-12-12 1986-06-13 Novo Industri As Fremgangsmaade til stabilisering af extra-chromosomale elementer i bakterier under dyrkning
JPH0644865B2 (ja) * 1985-10-29 1994-06-15 三菱瓦斯化学株式会社 カンピロバクタ−属細菌の培養方法
US5338670A (en) * 1986-07-28 1994-08-16 The United States Of America As Represented By The Department Of Health And Human Services Production of bordetella pertussis toxin with a low concentration of iron
IT1227657B (it) * 1988-12-01 1991-04-23 Mini Ricerca Scient Tecnolog Antibiotici ab-021 e processo per la loro produzione
JPH0822221B2 (ja) * 1988-12-28 1996-03-06 日東化学工業株式会社 シュードモナス属細菌の培養法
JPH02308754A (ja) * 1989-05-24 1990-12-21 Yakult Honsha Co Ltd 乳発酵食品の製造法
US5296221A (en) * 1990-01-31 1994-03-22 Sani-Ei Sucrochemical Co., Ltd. Lactobacillus johnsonii ferm bp-2680 lactic acid bacteria preparations using the same and a process of manufacturing the preparations
EP0555366B1 (en) * 1990-11-01 2000-06-28 Iowa State University Research Foundation, Inc. Bacterial attenuation method and vaccine
JP3043809B2 (ja) * 1991-11-15 2000-05-22 ファイザー・インコーポレイテッド グラム陰性菌ワクチン
DE4208785A1 (de) * 1992-03-19 1993-09-23 Degussa Verfahren zum auffinden von insertionselementen (is-elemente) oder transposonen
US5610059A (en) * 1992-11-09 1997-03-11 University Of Arizona Etiological agent for porcine enteritis

Also Published As

Publication number Publication date
DK1645567T4 (en) 2016-04-11
EP2199795A2 (en) 2010-06-23
DE69637251T2 (de) 2008-06-12
PL189286B1 (pl) 2005-07-29
CA2222643A1 (en) 1996-12-12
ES2173055T3 (es) 2005-07-01
NZ319994A (en) 2000-01-28
WO1996039629A1 (en) 1996-12-12
DE69634334D1 (de) 2005-03-17
EP0843818B2 (en) 2018-12-19
PL189287B1 (pl) 2005-07-29
JP4263212B2 (ja) 2009-05-13
ES2173055T1 (es) 2002-10-16
JP2006061165A (ja) 2006-03-09
EP1645567B2 (en) 2016-01-06
LU91405I2 (fr) 2008-02-21
DE69637251T3 (de) 2016-06-02
DK1403643T3 (da) 2010-01-04
RO118885B1 (ro) 2003-12-30
HUP9900884A2 (hu) 1999-07-28
EP0843818B1 (en) 2005-02-09
EP1403643A1 (en) 2004-03-31
PL325872A1 (en) 1998-08-17
JP5078740B2 (ja) 2012-11-21
KR20060129549A (ko) 2006-12-15
BG102130A (en) 1998-09-30
CA2222643C (en) 2013-08-13
PT1645567E (pt) 2007-11-19
KR20050048651A (ko) 2005-05-24
DE843818T1 (de) 2002-11-28
JP3920300B2 (ja) 2007-05-30
HK1010911A1 (en) 1999-07-02
DE122007000102I1 (de) 2008-04-17
KR19990022509A (ko) 1999-03-25
PL189250B1 (pl) 2005-07-29
DE69637251D1 (de) 2007-10-25
JP3765834B2 (ja) 2006-04-12
BR9608338B1 (pt) 2009-05-05
JP2007151554A (ja) 2007-06-21
BRPI9612938B1 (pt) 2010-07-27
KR100544857B1 (ko) 2006-01-24
EP1655607B1 (en) 2015-05-13
EP1403643B1 (en) 2009-09-02
ES2294620T3 (es) 2008-04-01
EP1645567B1 (en) 2007-09-12
DE69638016D1 (de) 2009-10-15
JP2008266340A (ja) 2008-11-06
NL300331I1 (nl) 2008-03-03
ATE441863T1 (de) 2009-09-15
EP2199795A3 (en) 2010-11-03
DE69634334T2 (de) 2006-04-13
EP0843818A4 (en) 2002-02-06
EP1655607A1 (en) 2006-05-10
ATE373015T1 (de) 2007-09-15
BG64292B1 (bg) 2004-08-31
EP2199795B1 (en) 2016-03-30
KR100758614B1 (ko) 2007-09-13
PL187850B1 (pl) 2004-10-29
CZ295933B6 (cs) 2005-12-14
US5885823A (en) 1999-03-23
BR9608338A (pt) 1999-01-05
RU2265849C2 (ru) 2005-12-10
AU6262796A (en) 1996-12-24
PL189187B1 (pl) 2005-07-29
EP1403643B2 (en) 2018-10-03
ES2332587T3 (es) 2010-02-09
ATE289069T1 (de) 2005-02-15
EP1645567A1 (en) 2006-04-12
FR07C0071I2 (fr) 2010-12-31
AU717045B2 (en) 2000-03-16
BRPI9612938B8 (pt) 2017-09-12
KR100513481B1 (ko) 2006-01-27
PT843818E (pt) 2005-04-29
PT1403643E (pt) 2009-10-08
RU2305707C2 (ru) 2007-09-10
RU2005114739A (ru) 2006-11-20
ES2294620T5 (es) 2016-03-23
NL300331I2 (nl) 2008-07-01
JPH11507225A (ja) 1999-06-29
CZ389997A3 (cs) 1998-07-15
KR20050046741A (ko) 2005-05-18
PL187849B1 (pl) 2004-10-29
HUP9900884A3 (en) 2001-01-29
HU230199B1 (hu) 2015-10-28
EP0843818A1 (en) 1998-05-27
MX9709464A (es) 1998-06-30
DK1645567T3 (da) 2007-11-26
DK0843818T3 (da) 2005-05-09

Similar Documents

Publication Publication Date Title
ES2294620T5 (es) Cultivo de Lawsonia intracellularis, vacunas anti-Lawsonia intracellularis y agentes de diagnóstico
Newton et al. Isolation of cyanobacteria from the aquatic fern, Azolla
HK1067662A1 (en) Lawsonia intracellularis cultivation, anti-lawsonia intracellularis vaccines and diagnostic agents
JPS5758884A (en) Preparation of glutathione peroxidase
AU634148B2 (en) Use of cellulase preparations in the cultivation and use of cellulose-producing microorganisms
JPS5743684A (en) Preparation of maltose dehydrogenase
JPS6474976A (en) Short-period 'sanpai' yeast culture using thermostable lactic acid bacteria
JPS5651989A (en) Preparation of l-valine by fermentation method
JPS57141289A (en) Preparation of amine oxidase
JPS56106590A (en) Preparation of galactose oxidase
JPS57206386A (en) Preparation of ethanolamine oxidase
JPS56106589A (en) Preparation of glutathione reductase
GR3004110T3 (pl)
TH112991B (th) การเลี้ยง Lawsonia intracellularis วัคซีนต้าน Lawsonia intracellluris และสารสำหรับใช้วินิจฉัย
JPS5786292A (en) Preparation of n-benzoyl-l-alanine acylase
JPS56106591A (en) Preparation of peroxidase