FR07C0071I2 - Culture de lawsonia intracellularis, vaccins anti-lawsonia intracellularis et agents de diagnostic - Google Patents
Culture de lawsonia intracellularis, vaccins anti-lawsonia intracellularis et agents de diagnosticInfo
- Publication number
- FR07C0071I2 FR07C0071I2 FR07C0071C FR07C0071C FR07C0071I2 FR 07C0071 I2 FR07C0071 I2 FR 07C0071I2 FR 07C0071 C FR07C0071 C FR 07C0071C FR 07C0071 C FR07C0071 C FR 07C0071C FR 07C0071 I2 FR07C0071 I2 FR 07C0071I2
- Authority
- FR
- France
- Prior art keywords
- bacteria
- lawsonia intracellularis
- infected cells
- cells
- attenuated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/105—Delta proteobacteriales, e.g. Lawsonia; Epsilon proteobacteriales, e.g. campylobacter, helicobacter
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/554—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being a biological cell or cell fragment, e.g. bacteria, yeast cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
- C12N9/92—Glucose isomerase (5.3.1.5; 5.3.1.9; 5.3.1.18)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/56922—Campylobacter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2469/00—Immunoassays for the detection of microorganisms
- G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/825—Bacterial vaccine for porcine species, e.g. swine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/465,337 US5714375A (en) | 1995-06-05 | 1995-06-05 | Ileal symbiont intracellularis propagation in suspended host cells |
US08/658,194 US5885823A (en) | 1995-06-05 | 1996-06-04 | Lawsonia intracellularis cultivation, anti-Lawsonia intracellularis vaccines and diagnostic agents |
EP96921391.7A EP0843818B2 (en) | 1995-06-05 | 1996-06-05 | Lawsonia intracellularis cultivation, anti-lawsonia intracellularis vaccines and diagnostic agents |
EP03022895.1A EP1403643B2 (en) | 1995-06-05 | 1996-06-05 | Lawsonia intracellularis cultivation, anti-lawsonia intracelluaris vaccines and diagnostic agents |
Publications (2)
Publication Number | Publication Date |
---|---|
FR07C0071I1 FR07C0071I1 (pl) | 2008-01-02 |
FR07C0071I2 true FR07C0071I2 (fr) | 2010-12-31 |
Family
ID=27041284
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR07C0071C Active FR07C0071I2 (fr) | 1995-06-05 | 2007-12-21 | Culture de lawsonia intracellularis, vaccins anti-lawsonia intracellularis et agents de diagnostic |
Country Status (24)
Country | Link |
---|---|
US (1) | US5885823A (pl) |
EP (5) | EP1645567B2 (pl) |
JP (4) | JP3765834B2 (pl) |
KR (4) | KR100758614B1 (pl) |
AT (3) | ATE373015T1 (pl) |
AU (1) | AU717045B2 (pl) |
BG (1) | BG64292B1 (pl) |
BR (2) | BR9608338B1 (pl) |
CA (1) | CA2222643C (pl) |
CZ (1) | CZ295933B6 (pl) |
DE (5) | DE122007000102I1 (pl) |
DK (3) | DK1645567T4 (pl) |
ES (3) | ES2294620T5 (pl) |
FR (1) | FR07C0071I2 (pl) |
HK (1) | HK1010911A1 (pl) |
HU (1) | HU230199B1 (pl) |
LU (1) | LU91405I2 (pl) |
NL (1) | NL300331I2 (pl) |
NZ (1) | NZ319994A (pl) |
PL (6) | PL187849B1 (pl) |
PT (3) | PT843818E (pl) |
RO (1) | RO118885B1 (pl) |
RU (2) | RU2265849C2 (pl) |
WO (1) | WO1996039629A1 (pl) |
Families Citing this family (61)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2000502054A (ja) * | 1995-11-30 | 2000-02-22 | アグリカルチャー ビクトリア サービシーズ ピーティーワイ.エルティーディー. | 治療用および診断用の組成物 |
FR2772047B1 (fr) * | 1997-12-05 | 2004-04-09 | Ct Nat D Etudes Veterinaires E | Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection |
JP2003501013A (ja) * | 1999-05-13 | 2003-01-14 | ファイザー プロダクツ インコーポレーティッド | ローソニア由来の遺伝子及び関連SodCポリペプチド、ぺプチド及びタンパク質並びにそれらの使用 |
AU767390B2 (en) * | 1999-05-13 | 2003-11-06 | Agriculture Victoria Services Pty Ltd | (lawsonia) derived gene and related OmpH polypeptides, peptides and proteins and their uses |
US7052697B1 (en) * | 1999-05-13 | 2006-05-30 | Agriculture Victoria Services Pty Ltd | Lawsonia derived gene and related OmpH polypeptides, peptides and proteins and their uses |
AU775323B2 (en) * | 1999-05-13 | 2004-07-29 | Agriculture Victoria Services Pty Ltd | Lawsonia derived gene and related hemolysin polypeptides, peptides and proteins and their uses |
US7029683B1 (en) | 1999-05-13 | 2006-04-18 | Pfizer Products, Inc. | Lawsonia derived gene and related hemolysin polypeptides, peptides and proteins and their uses |
BR0011294A (pt) * | 1999-05-13 | 2002-02-26 | Pfizer Prod Inc | Gene derivado lawsonia e polipeptìdeos, peptìdeos e proteìnas flge relacionados e seus usos |
US6605696B1 (en) * | 1999-10-22 | 2003-08-12 | Pfizer, Inc. | Lawsonia intracellularis proteins, and related methods and materials |
CA2423588A1 (en) * | 2000-09-29 | 2002-04-04 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Improved vaccines for proliferative ileitis and methods of making and using the same |
CA2399276A1 (en) * | 2000-11-10 | 2002-05-16 | Agriculture Victoria Services Pty, Ltd. | Novel therapeutic compositions for treating infection by lawsonia spp |
AUPR138100A0 (en) | 2000-11-10 | 2000-12-07 | Agriculture Victoria Services Pty Ltd | Novel therapeutic compositions for treating infection by lawsonia spp |
DE60144201D1 (de) * | 2000-12-20 | 2011-04-21 | Intervet Int Bv | Lawsonia intracellularis Impfstoff |
US20030087421A1 (en) * | 2001-07-11 | 2003-05-08 | Gebhart Connie J | Lawsonia intracellularis |
AU2003295341A1 (en) * | 2002-10-04 | 2004-05-04 | Regents Of The University Of Minnesota | Nucleic acid and polypeptide sequences from lawsonia intracellularis and methods of using |
PT1651260E (pt) * | 2003-07-25 | 2009-09-24 | Boehringer Ingelheim Vetmed | Lawsonia intracellularis de origem europeia e vacinas, agentes de diagnóstico e métodos para sua utilização |
DE602004024423D1 (de) | 2003-09-12 | 2010-01-14 | Intervet Int Bv | Impfstoff mit lawsonia intracellularis-untereinheit |
BRPI0417440A (pt) * | 2003-12-09 | 2007-03-06 | Intervet Int Bv | ácido nucleico, fragmento e molécula de dna, veìculo recombinante vivo, célula hospedeira, proteìna de lawsonia intracellularis, vacina para combater as infecções com lawsonia intracelularis, método para a preparação de uma vacina, e, testes de diagnóstico para aldetecção de anticorpos contra lawsonia intracellularis e material antigênico de lawsonia intracellularis |
WO2005070958A2 (en) * | 2004-01-22 | 2005-08-04 | Intervet International B.V | Lawsonia intracellularis subunit vaccines |
MY146476A (en) | 2004-06-24 | 2012-08-15 | Boehringer Ingelheim Vetmed | Method of diagnosing lawsonia intracellularis |
EP1609870A1 (en) * | 2004-06-24 | 2005-12-28 | Boehringer Ingelheim Vetmedica Gmbh | Method of diagnosing lawsonia intracellularis |
US20060021536A1 (en) * | 2004-07-30 | 2006-02-02 | Limin Song | Method for creating an absorbent article exhibiting a harmonic color scheme |
KR100621882B1 (ko) * | 2004-09-30 | 2006-09-19 | 건국대학교 산학협력단 | 돼지 증식성 회장염 감염돈에서 로소니아인트라셀룰라리스 균을 분리하는 방법 |
JP2008520231A (ja) * | 2004-11-24 | 2008-06-19 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | Lawsoniaintracellularisの培養方法 |
US20070212373A1 (en) * | 2004-12-08 | 2007-09-13 | Akzo Nobel N.V. | Lawsonia Intracellularis 26 Kd Subunit Vaccine |
UA95602C2 (ru) | 2004-12-30 | 2011-08-25 | Берингер Ингельхейм Ветмедика, Инк. | Иммуногенная композиция цвс2 и способы приготовления такой композиции |
US7700285B1 (en) | 2005-12-29 | 2010-04-20 | Boehringer Ingelheim Vetmedica, Inc. | PCV2 immunogenic compositions and methods of producing such compositions |
US7833707B2 (en) * | 2004-12-30 | 2010-11-16 | Boehringer Ingelheim Vetmedica, Inc. | Methods of overexpression and recovery of porcine circovirus type 2 ORF2 |
US8834891B2 (en) | 2005-03-14 | 2014-09-16 | Boehringer Ingelheim Vetmedica, Inc. | Immunogenic compositions comprising Lawsonia intracellularis |
US8398994B2 (en) * | 2005-07-15 | 2013-03-19 | Boehringer Ingelheim Vetmedica, Inc. | Lawsonia vaccine and methods of use thereof |
RU2488407C2 (ru) | 2005-12-29 | 2013-07-27 | Берингер Ингельхайм Ветмедика, Инк. | Поливалентные иммуногенные композиции pcv2 и способы получения таких композиций |
WO2007094893A2 (en) | 2005-12-29 | 2007-08-23 | Boehringer Ingelheim Vetmedica, Inc. | Use of a pcv2 immunogenic composition for lessening clinical symptoms in pigs |
US8470336B2 (en) * | 2006-05-25 | 2013-06-25 | Boehringer Ingelheim Vetmedica, Inc. | Vaccination of young animals against Lawsonia intracellularis infections |
US20080241190A1 (en) * | 2006-11-13 | 2008-10-02 | Boehringer Ingelheim Vetmedica, Inc. | Vaccination of horses against lawsonia intracellularis |
US20100129397A1 (en) * | 2006-12-11 | 2010-05-27 | Boehringer Ingelheim Vetmedica, Inc. | Effective method of treatment of porcine circovirus and lawsonia intracellularis infections |
PL2094872T5 (pl) | 2006-12-15 | 2020-10-05 | Boehringer Ingelheim Animal Health USA Inc. | Leczenie świń seropozytywnych wobec przeciwciała anty-pcv2 antygenem pcv2 |
EP1941903A1 (en) | 2007-01-03 | 2008-07-09 | Boehringer Ingelheim Vetmedica Gmbh | Prophylaxis and treatment of PRDC |
EP1958644A1 (en) * | 2007-02-13 | 2008-08-20 | Boehringer Ingelheim Vetmedica Gmbh | Prevention and treatment of sub-clinical pcvd |
US7829274B2 (en) * | 2007-09-04 | 2010-11-09 | Boehringer Ingelheim Vetmedica, Inc. | Reduction of concomitant infections in pigs by the use of PCV2 antigen |
WO2009037262A2 (en) * | 2007-09-17 | 2009-03-26 | Boehringer Ingelheim Vetmedica, Inc. | Method of preventing early lawsonia intracellularis infections |
BRPI0818248A2 (pt) * | 2007-10-12 | 2014-10-14 | Pfizer | Métodos de cultura de lawsonia intracellularis |
AU2008347235A1 (en) * | 2007-12-31 | 2009-07-16 | Boehringer Ingelheim Vetmedica, Inc. | PCV2 ORF2 virus like particle with foreign amino acid insertion |
CA2712006A1 (en) | 2008-01-23 | 2009-10-15 | Boehringer Ingelheim Vetmedica, Inc. | Pcv2 mycoplasma hyopneumoniae immunogenic compositions and methods of producing such compositions |
EP2254595A4 (en) * | 2008-02-15 | 2012-12-05 | Boehringer Ingelheim Vetmed | METHODS AND COMPOSITIONS FOR REDUCING THE IMPACT OF ENTERIC DISEASES |
TWI551295B (zh) | 2008-04-18 | 2016-10-01 | 英特威特國際股份有限公司 | 防備胞內勞森菌(Lawsonia intracellularis)用疫苗 |
TWI449533B (zh) | 2008-04-18 | 2014-08-21 | Intervet Int Bv | 防備胞內勞森菌(Lawsonia intracellularis)、豬肺炎黴漿菌(Mycoplasma hyopneumoniae)及豬環狀病毒(Porcine circo virus)用疫苗 |
US8557254B2 (en) | 2008-07-22 | 2013-10-15 | Intervet Inc. | Lawsonia intracellularis bacterium of a novel serotype, vaccine based on that bacterium, antibodies suitable for diagnosing the novel Lawsonia intracellularis serotype and hybridomas for producing the said antibodies |
US8142760B2 (en) * | 2008-09-05 | 2012-03-27 | Nathan Len Winkelman | Vaccination for Lawsonia intracellularis |
WO2011006880A1 (en) * | 2009-07-14 | 2011-01-20 | Intervet International B.V. | Lawsonia intracellularis propagation |
TWI627281B (zh) * | 2009-09-02 | 2018-06-21 | 百靈佳殷格翰家畜藥品公司 | 降低pcv-2組合物殺病毒活性之方法及具有改良免疫原性之pcv-2組合物 |
WO2011054951A1 (en) | 2009-11-09 | 2011-05-12 | Intervet International B.V. | Method to grow lawsonia intracellularis bacteria in persistently infected mccoy cells |
AU2013370983B2 (en) * | 2012-12-28 | 2019-09-26 | Boehringer Ingelheim Vetmedica Gmbh | Method of making a mycoplasma vaccine |
US9987348B2 (en) | 2013-09-25 | 2018-06-05 | Zoetis Services Llc | PCV2B divergent vaccine composition and methods of use |
CN105658660A (zh) | 2013-10-02 | 2016-06-08 | 勃林格殷格翰动物保健公司 | Pcv2 orf2蛋白变体和由其组成的病毒样颗粒 |
EP3253409B1 (en) | 2015-02-04 | 2020-05-06 | Intervet International B.V. | A vaccine for use against subclinical lawsonia infection in a pig |
JP2018504423A (ja) * | 2015-02-04 | 2018-02-15 | インターベット インターナショナル ベー. フェー. | 豚における無症候性ローソニア感染症に対する使用のためのワクチン |
KR20180062468A (ko) * | 2016-11-18 | 2018-06-11 | 녹십자수의약품(주) | 신규한 로소니아 인트라셀룰라리스 균주 및 이의 용도 |
CN111757752A (zh) | 2018-02-28 | 2020-10-09 | 勃林格殷格翰动物保健有限公司 | 用于减少动物中的粪臭素和/或吲哚的方法 |
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CA3231048A1 (en) | 2021-11-01 | 2023-05-04 | Boehringer Ingelheim Vetmedica Gmbh | Immunogenic gel compositions |
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