FI973183A0 - Diagnostiseen kuvantamiseen soveltuvia varjoaineita, joilla on pidentynyt viipymä veressä - Google Patents
Diagnostiseen kuvantamiseen soveltuvia varjoaineita, joilla on pidentynyt viipymä veressäInfo
- Publication number
- FI973183A0 FI973183A0 FI973183A FI973183A FI973183A0 FI 973183 A0 FI973183 A0 FI 973183A0 FI 973183 A FI973183 A FI 973183A FI 973183 A FI973183 A FI 973183A FI 973183 A0 FI973183 A0 FI 973183A0
- Authority
- FI
- Finland
- Prior art keywords
- blood
- contrast agents
- diagnostic imaging
- agents suitable
- prolonged residence
- Prior art date
Links
- 239000008280 blood Substances 0.000 title 1
- 210000004369 blood Anatomy 0.000 title 1
- 239000002872 contrast media Substances 0.000 title 1
- 238000002059 diagnostic imaging Methods 0.000 title 1
- 230000002035 prolonged effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
- A61K49/103—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being acyclic, e.g. DTPA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
- A61K49/106—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/50—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications
- A61B6/507—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications for determination of haemodynamic parameters, e.g. perfusion CT
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Radiology & Medical Imaging (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US38231795A | 1995-02-01 | 1995-02-01 | |
PCT/US1996/000164 WO1996023526A2 (en) | 1995-02-01 | 1996-01-16 | Diagnostic imaging contrast agents with extended blood retention |
Publications (2)
Publication Number | Publication Date |
---|---|
FI973183A FI973183A (fi) | 1997-07-31 |
FI973183A0 true FI973183A0 (fi) | 1997-07-31 |
Family
ID=23508434
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI973183A FI973183A0 (fi) | 1995-02-01 | 1997-07-31 | Diagnostiseen kuvantamiseen soveltuvia varjoaineita, joilla on pidentynyt viipymä veressä |
Country Status (25)
Country | Link |
---|---|
US (8) | US6676929B2 (it) |
EP (2) | EP0806968B1 (it) |
JP (4) | JP4064458B2 (it) |
KR (1) | KR100403755B1 (it) |
CN (3) | CN1177806C (it) |
AR (1) | AR006510A1 (it) |
AT (1) | ATE342738T1 (it) |
AU (1) | AU689700B2 (it) |
BR (1) | BR9607136A (it) |
CA (1) | CA2211100C (it) |
DE (3) | DE122006000061I1 (it) |
DK (1) | DK0806968T3 (it) |
ES (1) | ES2274523T3 (it) |
FI (1) | FI973183A0 (it) |
HK (2) | HK1002551A1 (it) |
IL (1) | IL116847A (it) |
IS (1) | IS2505B (it) |
MY (1) | MY128089A (it) |
NL (1) | NL300253I2 (it) |
NO (2) | NO326114B1 (it) |
NZ (1) | NZ301181A (it) |
PT (1) | PT806968E (it) |
TW (1) | TW319763B (it) |
WO (1) | WO1996023526A2 (it) |
ZA (1) | ZA96417B (it) |
Families Citing this family (106)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW319763B (it) * | 1995-02-01 | 1997-11-11 | Epix Medical Inc | |
US6713045B1 (en) | 1995-06-02 | 2004-03-30 | Research Corporation Technologies, Inc. | Targeted magnetic resonance imaging agents for the detection of physiological processes |
US6770261B2 (en) | 1995-06-02 | 2004-08-03 | Research Corporation Technologies | Magnetic resonance imaging agents for the detection of physiological agents |
DE19543077C2 (de) * | 1995-11-13 | 1997-10-16 | Schering Ag | Verwendung von gashaltigen Metallkomplexen als Ultraschallkontrastmittel |
EP0907379B1 (en) * | 1996-04-01 | 2004-06-02 | Epix Medical, Inc. | Bioactivated diagnostic imaging contrast agents |
US5900228A (en) | 1996-07-31 | 1999-05-04 | California Institute Of Technology | Bifunctional detection agents having a polymer covalently linked to an MRI agent and an optical dye |
US5919967A (en) * | 1997-04-11 | 1999-07-06 | Epix Medical, Inc. | Process for synthesizing phosphodiesters |
DE19744004C1 (de) * | 1997-09-26 | 1999-07-22 | Schering Ag | Lipophile Metall-Komplexe für Nekrose und Infarkt-Imaging |
US6495118B1 (en) | 1997-09-26 | 2002-12-17 | Schering Aktiengesellschaft | Lipophilic metal complexes for necrosis and infarction imaging |
WO1999017809A2 (en) * | 1997-10-02 | 1999-04-15 | Epix Medical, Inc. | Contrast-enhanced diagnostic imaging method for monitoring interventional therapies |
CA2307332C (en) * | 1997-10-27 | 2008-09-16 | California Institute Of Technology | Magnetic resonance imaging agents for the delivery of therapeutic agents |
US6713046B1 (en) | 1997-10-27 | 2004-03-30 | Research Corporation Technologies | Magnetic resonance imaging agents for the delivery of therapeutic agents |
CA2309749A1 (en) | 1997-11-17 | 1999-05-27 | Research Corporation Technologies, Inc. | Magnetic resonance imaging agents for the detection of physiological agents |
GB9912356D0 (en) | 1999-05-26 | 1999-07-28 | Btg Int Ltd | Generation of microfoam |
JP3848493B2 (ja) * | 1999-06-30 | 2006-11-22 | 英三 盛 | X線診断システム |
HUP0202635A3 (en) | 1999-07-29 | 2006-03-28 | Epix Medical Inc Cambridge | Targeting multimeric imaging agents through multilocus binding |
DE19964224B4 (de) * | 1999-09-09 | 2005-09-01 | Schering Ag | Pharmazeutische Mittel enthaltend Calcium-Komplex von [[(4R)-4-[bis[(carboxy-.kappa.O)methyl]amino-.kappa.N]-6,9-bis[(carboxy-.kappa.O)methyl]-1-[(4,4-diphenylcyclohexyl)oxy]-1-hydroxy-2-oxa-6,9-diaza-1-phosphaundecan-11-yl-säure-.kappa.N6,.kappa.N9,.kappa.011]1-oxidato(6-)]-, tetrahydrogen (MS-325) und dessen Salze sowie Verfahren zur Herstellung der Mittel |
US20030203879A1 (en) * | 1999-09-09 | 2003-10-30 | Schering Ag | Calcium complex of [[(4R)-4-[bis[(carboxy-.kappa.O)methyl]amino-.kappa.n]-6,9-bis[(carboxy.kappa.O)methyl]-1-[(4,4-diphenylcyclohexy)oxy]-1-hydroxy-2-oxa-6,9-diaza-1-phosphaundecan-11-ylic-acid-.kappa.N6,.Kappa.N9,.Kappa 011]1-oxidato(6-)]-, hexahydrogen, its salts, pharmaceutical agents that contain these complexes, their use in treatment and as additives in diagnosis, as well as processes for the production of the complexes and agents |
US6559330B1 (en) | 1999-09-09 | 2003-05-06 | Schering Aktiengesellschaft | Calcium complex of [[(4r)-4-[bis{carboxy-.kappa.o)methyl]amino-.kappa.n]-6,9-bis[(carboxy.kappa.o)methyl]-1-[(4,4-diphenylcyclohexyl)oxy]-1-hydroxy-2-oxa-6,9-diaza-1-phosphaundecan-11-ylic-acid-.kappa.n6,.kappa.n9,.kappa.011]1-oxidato(6-)]-, hexahydrogen, its salts, pharmaceutical agents that contain these complexes, their use in treatment and as additives in diagnosis, as well as processes for the production of the complexes and agents |
DE19944893C2 (de) * | 1999-09-09 | 2001-09-20 | Schering Ag | Calcium-Komplex von [[(4R)-4-[bis[(carboxy-.kappa.O)methyl]amino-. kappa.N]-6,9-bis[(carboxy-.kappa.O)methyl]-1-[(4,4-diphenylcyclohexyl)oxy]-1-hydroxy-2-oxa-6,9-diaza-1-phosphaundecan-11-yl-säure-.kappa.N6, .kappa.N9,.kappa.O11]1-oxidato(6-)]-, hexahydrogen, dessen Salze und diese Komplexe enthaltende pharmazeutische Mittel |
PT1072604E (pt) * | 1999-09-09 | 2001-08-30 | Schering Ag | Complexo de calcio do (4r)-4-bis(carboxi-kappa.o)metil amino-.kappa.n-6,9-bis(carboxy-.kappa.o)metil-1-(4,4-difenilciclo-hexil)oxi-1-hidroxi-2-oxa-6,9-diaza-1-fosfaundecan-11.oico-.kappa.n6,.kappa.n9,.kappa.o11 1-oxidato(6-)-,hexa-hidrogenado seus sais agentes farmaceuticos contendo estes complexos sua utilizacao terapeutica e como aditivos em agentes de diagnostico assim como um processo para a preparacao dos complexos e agentes |
US6548044B1 (en) | 1999-11-22 | 2003-04-15 | Epix Medical, Inc. | Imaging sexual response |
US20030082106A1 (en) * | 2000-01-22 | 2003-05-01 | Aleksandr Nivorozhkin | Magnetic resonance imaging using contrast agents bioactivated by enzymatic cleavage |
US6673333B1 (en) | 2000-05-04 | 2004-01-06 | Research Corporation Technologies, Inc. | Functional MRI agents for cancer imaging |
US6656450B2 (en) | 2000-07-17 | 2003-12-02 | California Institute Of Technology, Inc. | Macrocyclic magnetic resonance imaging contrast agents |
WO2002028441A2 (en) | 2000-10-04 | 2002-04-11 | California Institute Of Technology | Magnetic resonance imaging agents for in vivo labeling and detection of amyloid deposits |
US6549798B2 (en) | 2001-02-07 | 2003-04-15 | Epix Medical, Inc. | Magnetic resonance angiography data |
TWI221406B (en) | 2001-07-30 | 2004-10-01 | Epix Medical Inc | Systems and methods for targeted magnetic resonance imaging of the vascular system |
TWI284539B (en) | 2001-07-30 | 2007-08-01 | Epix Pharm Inc | A method for making a magnetic resonance (MR) imaging agent, a MR imaging contrast agent, a method for altering stability of a peptide and a modified peptide |
US8512680B2 (en) | 2001-08-08 | 2013-08-20 | Btg International Ltd. | Injectables in foam, new pharmaceutical applications |
EP1423136A4 (en) * | 2001-08-10 | 2007-07-25 | Epix Pharm Inc | POLYPEPTIDE CONJUGATES HAVING INCREASED CIRCULATION HALF-VIES |
WO2003029257A1 (de) * | 2001-09-27 | 2003-04-10 | Schering Aktiengesellschaft | (ethylen)-(propylen/butylen)-phosphodiester-triaminpentaessigsäure-derivate |
US7794693B2 (en) | 2002-03-01 | 2010-09-14 | Bracco International B.V. | Targeting vector-phospholipid conjugates |
US7261876B2 (en) | 2002-03-01 | 2007-08-28 | Bracco International Bv | Multivalent constructs for therapeutic and diagnostic applications |
CA2513044A1 (en) | 2002-03-01 | 2004-08-05 | Dyax Corp. | Kdr and vegf/kdr binding peptides and their use in diagnosis and therapy |
CA2477836A1 (en) | 2002-03-01 | 2003-09-12 | Dyax Corp. | Kdr and vegf/kdr binding peptides and their use in diagnosis and therapy |
US8623822B2 (en) | 2002-03-01 | 2014-01-07 | Bracco Suisse Sa | KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy |
US7226577B2 (en) | 2003-01-13 | 2007-06-05 | Bracco Imaging, S. P. A. | Gastrin releasing peptide compounds |
PL1944312T3 (pl) | 2003-03-03 | 2012-12-31 | Dyax Corp | Peptydy, które specyficznie wiążą receptor HGF (CMET) i ich zastosowanie |
BRPI0410635A (pt) | 2003-05-23 | 2006-06-13 | Epix Pharm Inc | isÈmeros enriquecidos e opticamente puros de ligantes de quelação e agentes de contraste |
US7251520B2 (en) * | 2003-07-08 | 2007-07-31 | General Electric Company | Method and apparatus of slice selective magnetization preparation for moving table MRI |
AR047692A1 (es) * | 2003-07-10 | 2006-02-08 | Epix Medical Inc | Imagenes de blancos estacionarios |
KR20060127001A (ko) | 2003-11-17 | 2006-12-11 | 비티지 인터내셔널 리미티드 | 치료학적 포말 |
US8048439B2 (en) | 2003-11-17 | 2011-11-01 | Btg International Ltd. | Therapeutic foam |
DE102004026102B4 (de) * | 2004-05-25 | 2006-08-24 | Schering Ag | Verfahren zur Herstellung von 1-Hydroxymethyl-1,3,5-triazapentan, Trihydrochlorid |
US7189879B2 (en) | 2004-05-25 | 2007-03-13 | Schering Ag | Process for the production of 1-hydroxymethyl-1,3,5-triazapentane, trihydrochloride |
EP1768558A4 (en) * | 2004-06-09 | 2009-11-25 | Kereos Inc | LIPOPHILES DERIVATIVES OF CHELATE MONOAMIDES |
DE102004062258B3 (de) * | 2004-12-23 | 2006-01-05 | Schering Ag | Hydroxypyridinon-Derivate, deren Metallkomplexe und deren Verwendung zur Herstellung von Konjugaten mit Biomolekülen |
US8778299B2 (en) | 2005-01-26 | 2014-07-15 | The Regents Of The University Of Colorado, A Body Corporate | Methods for diagnosis and intervention of hepatic disorders |
US8613904B2 (en) | 2005-01-26 | 2013-12-24 | The Regents Of The University Of Colorado | Methods for diagnosis and intervention of hepatic disorders |
CA2596863A1 (en) * | 2005-02-03 | 2006-08-10 | Epix Pharmaceuticals, Inc. | Steady state perfusion methods |
JP2006248978A (ja) | 2005-03-10 | 2006-09-21 | Mebiopharm Co Ltd | 新規なリポソーム製剤 |
GB0509824D0 (en) | 2005-05-13 | 2005-06-22 | Btg Int Ltd | Therapeutic foam |
WO2007002109A2 (en) * | 2005-06-20 | 2007-01-04 | The Regents Of The University Of California | Multidentate pyrone-derived chelators for medicinal imaging and chelation |
KR100762357B1 (ko) * | 2005-06-28 | 2007-10-05 | 원광대학교산학협력단 | 염증특이적 엠알 조영제 및 이의 제조방법 |
KR100762359B1 (ko) * | 2005-06-28 | 2007-10-05 | 원광대학교산학협력단 | 신생혈관특이적 엠알 조영제 및 이의 제조방법 |
US9339559B2 (en) | 2005-09-09 | 2016-05-17 | Georgia State University Research Foundation, Inc. | Targeted contrast agents and methods for targeting contrast agents |
WO2007009058A2 (en) * | 2005-07-13 | 2007-01-18 | Georgia State University Research Foundation, Inc. | Contrast agents and methods for preparing contrast agents |
WO2007073792A1 (de) * | 2005-12-19 | 2007-07-05 | Bayer Schering Pharma Aktiengesellschaft | Verfahren zur herstellung von 4,4-diphenylcyclohexanol |
US20080058636A1 (en) | 2005-12-29 | 2008-03-06 | Epix Pharmaceuticals, Inc. | Methods of myocardial imaging |
DE102006025940B4 (de) * | 2006-06-02 | 2009-11-05 | Siemens Ag | Dielektrisches Element, Verfahren zur Erzeugung von Magnetresonanzaufnahmen eines Untersuchungsobjekts und Verwendung des dielektrischen Elements |
EP2518155B1 (en) | 2006-08-04 | 2014-07-23 | Georgia State University Research Foundation, Inc. | Enzyme sensors, methods for preparing and using such sensors, and methods of detecting protease activity |
CA2660717A1 (en) * | 2006-08-17 | 2008-02-21 | Epix Pharmaceuticals, Inc. | Methods for lymph system imaging |
CA2671431C (en) * | 2006-12-14 | 2019-03-26 | Georgia State University Research Foundation, Inc. | Analyte sensors, methods for preparing and using such sensors, and methods of detecting analyte activity |
DE102007002726A1 (de) * | 2007-01-18 | 2008-07-31 | Bayer Schering Pharma Aktiengesellschaft | Neue Kaskaden-Polymer-Komplexe, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel |
JPWO2008108163A1 (ja) * | 2007-03-06 | 2010-06-10 | コニカミノルタホールディングス株式会社 | ガドリニウム化合物及びmri用造影剤 |
EP1982733A1 (en) * | 2007-04-17 | 2008-10-22 | Bayer Schering Pharma Aktiengesellschaft | Use of a contrast agent for magnetic resonance imaging of endoleaks |
WO2008144728A1 (en) * | 2007-05-21 | 2008-11-27 | Bracco Imaging S.P.A. | Conjugates which bind a blood protein such as human serum albumin and methods of using the same in diagnostic and therapeutic applications |
MX2010007501A (es) | 2008-01-08 | 2010-08-16 | Lantheus Medical Imaging Inc | Conjugados de n-alcoxiamida como agentes formadores de imagen. |
EP2257316B1 (en) | 2008-04-02 | 2018-11-07 | Georgia State University Research Foundation, Inc. | Contrast agents, methods for preparing contrast agents, and methods of imaging |
WO2010107832A1 (en) | 2009-03-17 | 2010-09-23 | Bracco Imaging Spa | Lhrh-ii peptide analogs |
WO2010121133A2 (en) | 2009-04-17 | 2010-10-21 | The General Hospital Corporation | Multimodal imaging of fibrin |
MX2011009716A (es) | 2009-03-19 | 2011-10-17 | Wyeth Llc | Metodos para la preparacion de acido [2-(8,9-dioxo)-2,6-diazabicic lo[5.2.0]non-1(7)-en-2-il)etil]fosfonico y precursores de este. |
EP2451776B1 (en) | 2009-07-08 | 2019-09-18 | Lantheus Medical Imaging, Inc. | N-alkoxyamide conjugates as imaging agents |
US20110071403A1 (en) * | 2009-09-21 | 2011-03-24 | Board Of Regents Of The University Of Texas System | Functional near-infrared fluorescence lymphatic mapping for diagnosing, accessing, monitoring and directing therapy of lymphatic disorders |
US20110077222A1 (en) | 2009-09-30 | 2011-03-31 | Mallinckrodt Inc. | Sustained-Release Opiate and Opiate Derivative Compositions |
JP5725561B2 (ja) * | 2009-10-15 | 2015-05-27 | 国立大学法人徳島大学 | ジエチレントリアミン五酢酸誘導体の製造方法およびジエチレントリアミン五酢酸誘導体 |
EP2432191A1 (en) * | 2010-09-15 | 2012-03-21 | Alcatel Lucent | Methods and systems for service delivery |
EP2715346B1 (en) | 2011-05-31 | 2020-07-15 | The Regents of the University of Colorado, A Body Corporate | Method for assessment of hepatic function and portal blood flow |
CN104168923A (zh) | 2012-03-05 | 2014-11-26 | 伯拉考成像股份公司 | 用于评价病理性组织内大分子转运的动态增强mri成像法和活性剂 |
US9091701B2 (en) | 2012-11-12 | 2015-07-28 | The Regents Of The University Of Colorado, A Body Corporate | Disease severity index for assessment of chronic liver disease and method for diagnosis of three distinct subtypes of primary sclerosing cholangitis |
TW201514188A (zh) * | 2013-03-13 | 2015-04-16 | Lantheus Medical Imaging Inc | 製備釓磷維塞三鈉單水合物之方法 |
US10471163B2 (en) | 2013-09-13 | 2019-11-12 | The General Hospital Corporation | Activatable fibrin-binding probes |
WO2015171543A1 (en) | 2014-05-05 | 2015-11-12 | California Institute Of Technology | Mutant akt-specific capture agents, compositions, and methods of using and making |
WO2015179258A2 (en) * | 2014-05-17 | 2015-11-26 | The Johns Hopkins University | Mri-guided intraarterial catheter-based method for predicting territory of local blood brain barrier opening |
US10471162B2 (en) | 2014-06-20 | 2019-11-12 | The General Hospital Corporation | Collagen targeted imaging probes |
EP3270951B1 (en) | 2015-03-16 | 2020-09-09 | California Institute of Technology | Botulinum neurotoxin-specific capture agents, compositions, and methods of using and making |
WO2017004211A1 (en) | 2015-06-29 | 2017-01-05 | Collagen Medical, LLC | Collagen imaging compositions |
CN108290927B (zh) | 2015-07-15 | 2022-06-24 | 加州理工学院 | Il-17f-特异性捕获剂、组合物以及使用和制造的方法 |
EP3334464B1 (en) | 2015-08-13 | 2024-04-10 | The General Hospital Corporation | Manganese-based chelate conjugates for molecular mr imaging |
CN109476721B (zh) | 2016-04-04 | 2022-06-28 | 英蒂分子公司 | Cd8-特异性捕获剂、组合物及使用和制备方法 |
EP3519425B1 (en) | 2016-09-29 | 2024-02-28 | Indi Molecular, Inc. | Compositions for detection, inhibition and imaging of indoleamine 2,3-dioxygenase 1 (ido1) and methods of making and using same |
WO2018085375A1 (en) | 2016-11-01 | 2018-05-11 | Ohio State Innovation Foundation | Methods for the iodination of biomolecules |
US11719705B2 (en) | 2017-06-15 | 2023-08-08 | Indi Molecular, Inc. | IL-17F and IL-17A-specific capture agents, compositions, and methods of using and making |
EP3661563A4 (en) * | 2017-07-31 | 2021-11-10 | The Ohio State Innovation Foundation | BIOMIMETIC NANOMATERIALS AND USES THEREOF |
WO2019118592A1 (en) * | 2017-12-12 | 2019-06-20 | Massachusetts Institute Of Technology | Cell-permeable imaging sensors and uses thereof |
TWI667996B (zh) | 2018-03-23 | 2019-08-11 | 中國醫藥大學附設醫院 | 乳房腫瘤輔助檢測模型及乳房腫瘤輔助檢測系統 |
WO2020093055A2 (en) | 2018-11-02 | 2020-05-07 | Indi Molecular, Inc. | Peptide libraries with non-canonical amino acids |
WO2020097531A1 (en) | 2018-11-08 | 2020-05-14 | Indi Molecular, Inc. | Theranostic capture agents, compositions, and methods of using and making |
US20200291391A1 (en) | 2019-03-12 | 2020-09-17 | Indi Molecular, Inc. | Cross-linked epitopes and methods of use thereof |
US20220218834A1 (en) | 2019-05-20 | 2022-07-14 | Ohio State Innovation Foundation | Apohemoglobin-haptoglobin complexes and methods of using thereof |
US20200371101A1 (en) | 2019-05-20 | 2020-11-26 | Indi Molecular, Inc. | Compositions and methods relating to detection, inhibition, and imaging of indoleamine 2,3-dioxygenase 1 (ido1) |
US11414460B2 (en) | 2019-07-19 | 2022-08-16 | Institute For Systems Biology | KRAS-specific capture agents, compositions, and methods of making and using |
MX2022013633A (es) | 2020-04-30 | 2023-02-09 | Sairopa B V | Anticuerpos anti-cd103. |
WO2022098743A1 (en) | 2020-11-03 | 2022-05-12 | Indi Molecular, Inc. | Compositions, imaging, and therapeutic methods targeting folate receptor 1 (folr1) |
WO2022098745A1 (en) | 2020-11-03 | 2022-05-12 | Indi Molecular, Inc. | Compositions, delivery systems, and methods useful in tumor therapy |
Family Cites Families (102)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US488008A (en) * | 1892-12-13 | Method of forming dental crowns | ||
DE450742C (de) | 1924-12-04 | 1927-10-15 | Arthur Korn Dr | Verfahren zur drahtlosen UEbertragung von Bildern |
US3632637A (en) | 1968-02-13 | 1972-01-04 | Arthur E Martell | Hydroxyaryl-containing aminocarboxylic chelating agents |
US4088747A (en) | 1975-02-19 | 1978-05-09 | Australian Atomic Energy Commission | Phenolic amino-carboxylic acid radiopharmaceuticals |
FR2354993A1 (fr) | 1976-06-16 | 1978-01-13 | Dabeer | Procede pour la preparation de derives phenoliques d'acides hydroxyalcoyl-alcoylene-diaminoacetiques et de leurs sels |
US4150047A (en) | 1978-03-06 | 1979-04-17 | Air Products And Chemicals, Inc. | Process for preparing halogenated metal chelates |
IN152852B (it) * | 1978-08-09 | 1984-04-21 | Gen Electric Co Ltd | |
US4352751A (en) | 1979-09-10 | 1982-10-05 | Analytical Radiation Corporation | Species-linked diamine triacetic acids and their chelates |
US4308249A (en) | 1979-12-13 | 1981-12-29 | G. D. Searle & Co. | Radiopharmaceutical complexes of N-(tri-substituted alkyl)-iminodiacetic acids |
US4331647A (en) | 1980-03-03 | 1982-05-25 | Goldenberg Milton David | Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers |
US4361544A (en) | 1980-03-03 | 1982-11-30 | Goldenberg Milton David | Tumor localization and therapy with labeled antibodies specific to intracellular tumor-associated markers |
US4401647A (en) | 1980-03-03 | 1983-08-30 | The Regents Of The University Of Ca | Radiolabeled neoglycopeptides |
US4308149A (en) | 1980-07-14 | 1981-12-29 | Nalco Chemical Company | Branched/cross-linked cationic phenol-formaldehyde polymers useful in wastewater treatment |
US4957939A (en) | 1981-07-24 | 1990-09-18 | Schering Aktiengesellschaft | Sterile pharmaceutical compositions of gadolinium chelates useful enhancing NMR imaging |
US4647447A (en) | 1981-07-24 | 1987-03-03 | Schering Aktiengesellschaft | Diagnostic media |
DE3129906C3 (de) | 1981-07-24 | 1996-12-19 | Schering Ag | Paramagnetische Komplexsalze, deren Herstellung und Mittel zur Verwendung bei der NMR-Diagnostik |
US4472509A (en) | 1982-06-07 | 1984-09-18 | Gansow Otto A | Metal chelate conjugated monoclonal antibodies |
NL194579C (nl) | 1983-01-21 | 2002-08-05 | Schering Ag | Diagnostisch middel. |
FR2550449B1 (fr) | 1983-08-12 | 1986-01-31 | Commissariat Energie Atomique | Agents de relaxation specifiques d'organes ou de pathologies, utilisables pour modifier les contrastes en imagerie medicale par resonance magnetique nucleaire |
US4615879A (en) | 1983-11-14 | 1986-10-07 | Vanderbilt University | Particulate NMR contrast agents for gastrointestinal application |
SE463651B (sv) | 1983-12-21 | 1991-01-07 | Nycomed As | Diagnostikum och kontrastmedel |
GB8413772D0 (en) | 1984-05-30 | 1984-07-04 | Nyegaard & Co As | Chemical compounds |
GB8413849D0 (en) | 1984-05-31 | 1984-07-04 | Amersham Int Plc | Nmr contrast agents |
CA1260827A (en) | 1984-08-31 | 1989-09-26 | Richard C. Siegel | Antibody-metal ion complexes |
US4687658A (en) | 1984-10-04 | 1987-08-18 | Salutar, Inc. | Metal chelates of diethylenetriaminepentaacetic acid partial esters for NMR imaging |
US4687659A (en) | 1984-11-13 | 1987-08-18 | Salutar, Inc. | Diamide-DTPA-paramagnetic contrast agents for MR imaging |
US4859451A (en) | 1984-10-04 | 1989-08-22 | Salutar, Inc. | Paramagnetic contrast agents for MR imaging |
US4639365A (en) | 1984-10-18 | 1987-01-27 | The Board Of Regents, The University Of Texas System | Gadolinium chelates as NMR contrast agents |
US4746507A (en) | 1985-04-02 | 1988-05-24 | Salutar, Inc. | EDHPA based contrast agents for MR imaging, apparatus and methods |
US4880008A (en) | 1985-05-08 | 1989-11-14 | The General Hospital Corporation | Vivo enhancement of NMR relaxivity |
US4899755A (en) | 1985-05-08 | 1990-02-13 | The General Hospital Corporation | Hepatobiliary NMR contrast agents |
US5250285A (en) | 1985-05-08 | 1993-10-05 | The General Hospital Corporation | Hydroxy-aryl metal chelates for diagnostic NMR imaging |
US5525338A (en) | 1992-08-21 | 1996-06-11 | Immunomedics, Inc. | Detection and therapy of lesions with biotin/avidin conjugates |
US5512332A (en) | 1985-10-04 | 1996-04-30 | Immunivest Corporation | Process of making resuspendable coated magnetic particles |
US5017359A (en) | 1985-11-01 | 1991-05-21 | Centre National De La Recherche Scientifique | Aerosol compositions for in vivo imaging and therapy |
US5223242A (en) * | 1985-11-05 | 1993-06-29 | The General Hospital Corporation | Negatively charged specific affinity reagents |
FI72080C (fi) | 1986-01-17 | 1987-04-13 | Erkki Tapio Tuhkanen | Upphaengningsfaeste av foervaringsroer foer dokument. |
DE3772785D1 (de) | 1986-01-23 | 1991-10-17 | Squibb & Sons Inc | 1-substituiertes-4,7,10-triscarboxymethyl-1,4,7,10-tetraazacyclododecan und analoga. |
US4885363A (en) | 1987-04-24 | 1989-12-05 | E. R. Squibb & Sons, Inc. | 1-substituted-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs |
MX174467B (es) * | 1986-01-23 | 1994-05-17 | Squibb & Sons Inc | 1,4,7-triscarboximetil-1,4,7,10-tetraazaciclodo decano substituido en 1 y compuestos analogos |
IT1213029B (it) | 1986-01-30 | 1989-12-07 | Bracco Ind Chimica Spa | Chelati di ioni metallici paramagnetici. |
US4834964A (en) | 1986-03-07 | 1989-05-30 | M.R.I., Inc. | Use of charged nitroxides as NMR image enhancing agents for CSF |
EP0250358A3 (en) | 1986-06-20 | 1988-10-05 | Schering Aktiengesellschaft | Novel complex compounds |
US5314679A (en) | 1986-07-03 | 1994-05-24 | Advanced Magnetics Inc. | Vascular magnetic resonance imaging agent comprising nanoparticles |
AU608759B2 (en) | 1986-08-04 | 1991-04-18 | Amersham Health Salutar Inc | NMR imaging with paramagnetic polyvalents metal salts of poly-(acid-alkylene-amido)-alkanes |
JPS6390586A (ja) * | 1986-09-29 | 1988-04-21 | リ−・フア−マス−テイカルズ・インコ−ポレイテツド | 改良された接着タブ系 |
US5057302A (en) | 1987-02-13 | 1991-10-15 | Abbott Laboratories | Bifunctional chelating agents |
DE3710730A1 (de) | 1987-03-31 | 1988-10-20 | Schering Ag | Substituierte komplexbildner, komplexe und komplexsalze, verfahren zu deren herstellung und diese enthaltende pharmazeutische mittel |
US5091169A (en) * | 1987-05-08 | 1992-02-25 | Salutar, Inc. | Dipyridoxyl phosphate NMRI contrast agent compositions |
US4842845A (en) | 1987-05-08 | 1989-06-27 | Salutar, Inc. | Radioactive metal chelates for dipyridoxyl phosphate |
US4935518A (en) | 1987-05-08 | 1990-06-19 | Salutar, Inc. | Manganese(II), chelate contrast agents derived from N,N'-bis-(pyridoxal ethylene diamine-N,N')-diacetic acid and derivatives thereof |
AR246956A1 (es) | 1987-05-08 | 1994-10-31 | Salutar Inc | Compuesto quelante, un intermediario para preparar el mismo, y un procedimiento para preparar una composicion de medio de contraste. |
US5223243A (en) | 1987-05-08 | 1993-06-29 | Salutar, Inc. | Dipyridoxyl phosphate chelating compound intermediates useful as NMRI contrast agents |
GB8719041D0 (en) | 1987-08-12 | 1987-09-16 | Parker D | Conjugate compounds |
GB8719042D0 (en) | 1987-08-12 | 1987-09-16 | Parker D | Conjugate compounds |
DE3728600A1 (de) | 1987-08-27 | 1989-03-09 | Hoechst Ag | Verfahren zur markierung von substanzen mit technetium oder rhenium |
US5635180A (en) | 1988-02-17 | 1997-06-03 | Neorx Corporation | Alteration of pharmacokinetics of proteins by charge modification |
DE3806795A1 (de) | 1988-02-29 | 1989-09-07 | Schering Ag | Polymer-gebundene komplexbildner, deren komplexe und konjugate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
US5513332A (en) | 1988-05-31 | 1996-04-30 | Extended Systems, Inc. | Database management coprocessor for on-the-fly providing data from disk media to all without first storing data in memory therebetween |
KR0130770B1 (ko) | 1988-06-24 | 1998-04-17 | 나가이 아쯔시 | 테이프 카트리지 |
WO1989012631A1 (en) | 1988-06-24 | 1989-12-28 | The Dow Chemical Company | Macrocyclic bifunctional chelants, complexes thereof and their antibody conjugates |
DE3825278A1 (de) * | 1988-07-26 | 1990-02-01 | Basf Lacke & Farben | Verfahren zur herstellung von mehrschichtigen, schuetzenden und/oder dekorativen ueberzuegen auf substratoberflaechen |
JP2854905B2 (ja) | 1988-09-27 | 1999-02-10 | サリユーター・インコーポレイテツド | キレート組成物 |
BR8907282A (pt) | 1988-12-23 | 1991-03-12 | Dow Chemical Co | Processo para preparar complexos de metal funcionalizados com isotiocianato |
US5078986A (en) | 1989-02-15 | 1992-01-07 | Mallinckrodt Medical, Inc. | Method for enhancing magnetic resonance imaging using an image altering agent containing an excess of chelating agent |
FR2643370B1 (fr) | 1989-02-22 | 1991-08-23 | Air Liquide | Derives polyazotes et leurs complexes metalliques utilisables pour la fixation de l'oxygene |
DE3922005A1 (de) | 1989-06-30 | 1991-01-10 | Schering Ag | Derivatisierte dtpa-komplexe, diese verbindungen enthaltende pharmazeutische mittel, ihre verwendung und verfahren zu deren herstellung |
US5695739A (en) * | 1989-06-30 | 1997-12-09 | Schering Aktiengesellschaft | Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production |
US5094848A (en) | 1989-06-30 | 1992-03-10 | Neorx Corporation | Cleavable diphosphate and amidated diphosphate linkers |
JPH05503072A (ja) * | 1989-08-28 | 1993-05-27 | ザ・ゼネラル・ホスピタル・コーポレーション | 診断用nmr映像化の為のヒドロキシ―アリール金属キレート |
EP0418419B1 (de) * | 1989-09-22 | 1994-12-14 | Deutsche ITT Industries GmbH | Zweiphasentaktgenerator |
IN172208B (it) | 1990-04-02 | 1993-05-01 | Sint Sa | |
GB9007431D0 (en) | 1990-04-03 | 1990-05-30 | Shell Int Research | Diesel fuel additives |
DE4011684A1 (de) | 1990-04-06 | 1991-10-10 | Schering Ag | Dtpa-monoamide, diese verbindungen enthaltende pharmazeutische mittel, ihre verwendung und verfahren zu deren herstellung |
IE911297A1 (en) | 1990-04-18 | 1991-10-23 | Celltech Therapeutics Ltd | Tetra-aza macrocycles, processes for their preparation, and¹their use in magnetic resonance imaging |
CA2039399C (en) | 1990-04-25 | 2000-09-05 | C. Allen Chang | Dual functioning excipient for metal chelate contrast agents |
EP0485563B1 (de) * | 1990-05-30 | 1994-12-21 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Polyethersubstituierte tumormittel |
US5487390A (en) | 1990-10-05 | 1996-01-30 | Massachusetts Institute Of Technology | Gas-filled polymeric microbubbles for ultrasound imaging |
DE4035760A1 (de) | 1990-11-08 | 1992-05-14 | Schering Ag | Mono-n-substituierte 1,4,7,10-tetraazacyclododecan-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
TW213864B (it) | 1991-08-01 | 1993-10-01 | Squibb & Sons Inc | |
EP0598837A4 (en) | 1991-08-09 | 1994-07-13 | Univ California | Amino acid, ester and/or catechol contrast agents for mri. |
US5385719A (en) * | 1991-09-24 | 1995-01-31 | Unger; Evan C. | Copolymers and their use as contrast agents in magnetic resonance imaging and in other applications |
JP2894879B2 (ja) * | 1991-10-04 | 1999-05-24 | 日本メジフィジックス株式会社 | 診断用造影剤 |
US5407659A (en) | 1991-10-22 | 1995-04-18 | Mallinckrodt Medical, Inc. | Treated calcium/oxyanion-containing particles for medical diagnostic imaging |
US5464696A (en) | 1992-08-13 | 1995-11-07 | Bracco International B.V. | Particles for NMR imaging |
US5362478A (en) | 1993-03-26 | 1994-11-08 | Vivorx Pharmaceuticals, Inc. | Magnetic resonance imaging with fluorocarbons encapsulated in a cross-linked polymeric shell |
US5318769A (en) | 1993-03-31 | 1994-06-07 | Sterling Winthrop Inc. | Compositions of iodophenyl esters for X-ray visualization of the gastrointestinal tract |
US5365180A (en) * | 1993-04-16 | 1994-11-15 | National Semiconductor Corporation | Method for measuring contact resistance |
AU6996594A (en) | 1993-06-02 | 1994-12-20 | Bracco S.P.A. | Iodinated paramagnetic chelates, and their use as contrast agents |
US5358704A (en) | 1993-09-30 | 1994-10-25 | Bristol-Myers Squibb | Hepatobiliary tetraazamacrocyclic magnetic resonance contrast agents |
DE4341724A1 (de) | 1993-12-03 | 1995-06-08 | Schering Ag | Halogenaryl-substituierte Metallkomplexe enthaltende pharmazeutische Mittel, deren Verwendung in der Diagnostik, sowie Verfahren zur Herstellung der Komplexe und Mittel |
EP0661279B1 (fr) | 1993-12-30 | 2001-03-07 | Guerbet | Ligands polyaminés, complexes métalliques, procédé de préparation, applications diagnostiques et thérapeutiques |
NO940115D0 (no) * | 1994-01-13 | 1994-01-13 | Nycomed Imaging As | Kontrastmidler for roentgen- og magnettomografisk avbildning |
JP3878208B2 (ja) | 1994-04-08 | 2007-02-07 | ブラッコ インターナショナル ベスローテン フェンノートシャップ | 芳香族アミド化合物およびそれらのキレート |
GB9407435D0 (en) | 1994-04-14 | 1994-06-08 | Nycomed Salutar Inc | Compounds |
IT1269839B (it) | 1994-05-26 | 1997-04-15 | Bracco Spa | Coniugati di acidi biliari, loro derivati con complessi metallici e relativi usi |
TW319763B (it) * | 1995-02-01 | 1997-11-11 | Epix Medical Inc | |
IT1283650B1 (it) | 1996-08-02 | 1998-04-23 | Bracco Spa | Chelati paramagnetici ad alta relassivita' in siero |
US6342598B1 (en) * | 1998-11-26 | 2002-01-29 | Bracco International B.V. | Amphipatic polycarboxylic chelates and complexes with paramagnetic metals as MRI contrast agents |
IT1304501B1 (it) | 1998-12-23 | 2001-03-19 | Bracco Spa | Uso di derivati di acidi biliari coniugati con complessi metallicicome "blood pool agents" per l'indagine diagnostica tramite risonanza |
HUP0202635A3 (en) * | 1999-07-29 | 2006-03-28 | Epix Medical Inc Cambridge | Targeting multimeric imaging agents through multilocus binding |
IT1313617B1 (it) * | 1999-08-31 | 2002-09-09 | Bracco Spa | Processo per la preparazione di derivati degli acidi biliari. |
-
1995
- 1995-12-29 TW TW084114108A patent/TW319763B/zh active
-
1996
- 1996-01-16 CN CNB961917474A patent/CN1177806C/zh not_active Expired - Lifetime
- 1996-01-16 AU AU46543/96A patent/AU689700B2/en not_active Ceased
- 1996-01-16 CN CNA2006100957916A patent/CN101011586A/zh active Pending
- 1996-01-16 DK DK96902106T patent/DK0806968T3/da active
- 1996-01-16 BR BR9607136A patent/BR9607136A/pt not_active Application Discontinuation
- 1996-01-16 AT AT96902106T patent/ATE342738T1/de active
- 1996-01-16 EP EP96902106A patent/EP0806968B1/en not_active Expired - Lifetime
- 1996-01-16 WO PCT/US1996/000164 patent/WO1996023526A2/en active IP Right Grant
- 1996-01-16 NZ NZ301181A patent/NZ301181A/xx not_active IP Right Cessation
- 1996-01-16 CN CNB200410083591XA patent/CN100361711C/zh not_active Expired - Lifetime
- 1996-01-16 DE DE1996636635 patent/DE122006000061I1/de active Pending
- 1996-01-16 ES ES96902106T patent/ES2274523T3/es not_active Expired - Lifetime
- 1996-01-16 EP EP06016539A patent/EP1716871A3/en not_active Withdrawn
- 1996-01-16 KR KR1019970705230A patent/KR100403755B1/ko not_active IP Right Cessation
- 1996-01-16 JP JP52354396A patent/JP4064458B2/ja not_active Expired - Fee Related
- 1996-01-16 DE DE69636635T patent/DE69636635T2/de not_active Expired - Lifetime
- 1996-01-16 PT PT96902106T patent/PT806968E/pt unknown
- 1996-01-16 CA CA002211100A patent/CA2211100C/en not_active Expired - Lifetime
- 1996-01-18 ZA ZA96417A patent/ZA96417B/xx unknown
- 1996-01-22 IL IL11684796A patent/IL116847A/xx not_active IP Right Cessation
- 1996-01-29 AR ARP960101186A patent/AR006510A1/es active IP Right Grant
- 1996-01-29 MY MYPI96000321A patent/MY128089A/en unknown
-
1997
- 1997-07-14 IS IS4523A patent/IS2505B/is unknown
- 1997-07-30 NO NO19973510A patent/NO326114B1/no not_active IP Right Cessation
- 1997-07-31 FI FI973183A patent/FI973183A0/fi not_active Application Discontinuation
-
1998
- 1998-02-09 HK HK98100980A patent/HK1002551A1/xx not_active IP Right Cessation
-
2001
- 2001-12-20 US US10/034,522 patent/US6676929B2/en not_active Expired - Lifetime
-
2002
- 2002-12-19 JP JP2002369062A patent/JP2004026793A/ja not_active Withdrawn
-
2003
- 2003-01-30 US US10/354,723 patent/US7011815B2/en not_active Expired - Fee Related
-
2004
- 2004-01-12 US US10/755,506 patent/US7060250B2/en not_active Expired - Fee Related
- 2004-01-12 US US10/755,507 patent/US7229606B2/en not_active Expired - Fee Related
-
2005
- 2005-11-18 HK HK05110409A patent/HK1078468A1/xx not_active IP Right Cessation
-
2006
- 2006-06-22 US US11/472,842 patent/US8017105B2/en not_active Expired - Fee Related
- 2006-08-22 JP JP2006225515A patent/JP2006342181A/ja not_active Withdrawn
- 2006-09-25 US US11/526,312 patent/US20070020185A1/en not_active Abandoned
- 2006-09-25 US US11/526,302 patent/US20070020184A1/en not_active Abandoned
- 2006-11-10 DE DE200612000061 patent/DE122006000061I2/de active Active
-
2007
- 2007-01-05 NL NL300253C patent/NL300253I2/nl unknown
-
2008
- 2008-03-14 NO NO20081355A patent/NO20081355L/no not_active Application Discontinuation
- 2008-04-01 JP JP2008095587A patent/JP4950110B2/ja not_active Expired - Fee Related
-
2011
- 2011-08-29 US US13/220,103 patent/US8394356B2/en not_active Expired - Fee Related
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FI973183A0 (fi) | Diagnostiseen kuvantamiseen soveltuvia varjoaineita, joilla on pidentynyt viipymä veressä | |
DE69805455D1 (de) | Diagnostische Bilderzeugung | |
DE69411800D1 (de) | Bilderzeugungsgerät mit Getriebeeinheit. | |
DE19500856C2 (de) | Ultraschall-Diagnosesystem | |
NL1006411A1 (nl) | Medische inrichting. | |
BR9704528B1 (pt) | aparelho de captação de imagem multidirecional. | |
FI965094A (fi) | 2,4,6-trijodi-5-substituoituja aminoisoftalaattiestereitä, jotka ovat hyödyllisiä varjoaineina lääketieteellisessä diagnostisessa kuvauksessa | |
FI954967A0 (fi) | Diagnostinen kuvausaine | |
FR2716375B3 (fr) | Injecteur médical. | |
ZA976891B (en) | Diagnostic imaging contrast agent. | |
DE69933833D1 (de) | Ultraschall-Diagnosesystem | |
DE59100749D1 (de) | Röntgendiagnostikanlage. | |
FR2721278B1 (fr) | Véhicule de transport à traction humaine. | |
KR970034510U (ko) | 뒷면에 모니터가 부착된 자동차용 시트 | |
SI0806968T1 (sl) | Kontrastna sredstva za diagnosticno slikanje s podaljsano retencijo v krvi | |
DE59007633D1 (de) | Röntgendiagnostikanlage. | |
KR970050997U (ko) | 의료용자석 | |
ES1028612Y (es) | Impulsor-aspirador de uso clinico. | |
FR2717376B1 (fr) | Civière jetable perfectionnée. | |
ES1031891Y (es) | Consola perfeccionada. | |
ES1028691Y (es) | Bandeja de hospital perfeccionada. | |
ES1029166Y (es) | Estructura de asiento perfeccionada. | |
KR960025578U (ko) | 통신설비용 지. 피. 에스 안테나 고정장치 | |
ES1028973Y (es) | Cuaderno perfeccionado de uso infantil. | |
FR2714804B1 (fr) | Fauteuil de relaxation. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Transfer of assignment of patent |
Owner name: EPIX PHARMACEUTICALS, INC. Free format text: EPIX PHARMACEUTICALS, INC. |
|
FD | Application lapsed |