FI933450A - Nya steroider - Google Patents

Nya steroider Download PDF

Info

Publication number
FI933450A
FI933450A FI933450A FI933450A FI933450A FI 933450 A FI933450 A FI 933450A FI 933450 A FI933450 A FI 933450A FI 933450 A FI933450 A FI 933450A FI 933450 A FI933450 A FI 933450A
Authority
FI
Finland
Prior art keywords
steroider
nya
nya steroider
Prior art date
Application number
FI933450A
Other languages
English (en)
Other versions
FI933450A0 (fi
Inventor
Paul Andersson
Bengt Axelsson
Ralph Brattsand
Arne Thalen
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of FI933450A publication Critical patent/FI933450A/fi
Publication of FI933450A0 publication Critical patent/FI933450A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0092—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by an OH group free esterified or etherified
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI933450A 1991-02-04 1993-08-03 Nya steroider FI933450A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9100341A SE9100341D0 (sv) 1991-02-04 1991-02-04 Novel steroids
PCT/SE1992/000055 WO1992013872A1 (en) 1991-02-04 1992-01-29 Novel steroids

Publications (2)

Publication Number Publication Date
FI933450A true FI933450A (fi) 1993-08-03
FI933450A0 FI933450A0 (fi) 1993-08-03

Family

ID=20381806

Family Applications (1)

Application Number Title Priority Date Filing Date
FI933450A FI933450A0 (fi) 1991-02-04 1993-08-03 Nya steroider

Country Status (40)

Country Link
US (2) US5674861A (fi)
EP (1) EP0570454B1 (fi)
JP (1) JPH06505232A (fi)
KR (1) KR100216720B1 (fi)
CN (3) CN1034868C (fi)
AP (1) AP366A (fi)
AT (1) ATE178611T1 (fi)
BG (1) BG62211B1 (fi)
CA (1) CA2103924A1 (fi)
CZ (1) CZ281685B6 (fi)
DE (1) DE69228870T2 (fi)
DK (1) DK0570454T3 (fi)
DZ (1) DZ1553A1 (fi)
EE (1) EE03111B1 (fi)
ES (1) ES2133315T3 (fi)
FI (1) FI933450A0 (fi)
GR (1) GR3030657T3 (fi)
HK (1) HK1010733A1 (fi)
HU (1) HU218275B (fi)
IE (1) IE920166A1 (fi)
IL (1) IL100532A (fi)
IS (1) IS1601B (fi)
MA (1) MA22406A1 (fi)
MX (1) MX9200324A (fi)
NO (1) NO304073B1 (fi)
NZ (1) NZ241210A (fi)
PH (1) PH31284A (fi)
PL (1) PL170000B1 (fi)
PT (1) PT100086B (fi)
RO (1) RO111195B1 (fi)
RU (1) RU2111212C1 (fi)
SE (1) SE9100341D0 (fi)
SG (1) SG52557A1 (fi)
SI (1) SI9210065B (fi)
SK (1) SK281801B6 (fi)
TN (1) TNSN92007A1 (fi)
UA (1) UA41267C2 (fi)
WO (1) WO1992013872A1 (fi)
YU (1) YU48892B (fi)
ZA (1) ZA92233B (fi)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9100341D0 (sv) * 1991-02-04 1991-02-04 Astra Ab Novel steroids
WO1994015947A1 (en) * 1993-01-08 1994-07-21 Astra Aktiebolag Novel colon- or ileum-specific steroid derivatives
US5983956A (en) * 1994-10-03 1999-11-16 Astra Aktiebolag Formulation for inhalation
US5980949A (en) * 1994-10-03 1999-11-09 Astra Aktiebolag Formulation for inhalation
GB9423919D0 (en) * 1994-11-26 1995-01-11 Rhone Poulenc Rorer Ltd Chemical process
SE9700133D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
SE9700135D0 (sv) 1997-01-20 1997-01-20 Astra Ab New formulation
IT1291288B1 (it) 1997-04-30 1999-01-07 Farmabios Srl Processo per la preparazione di 16,17 acetali di derivati pregnanici con controllo della distribuzione epimerica al c-22.
ES2347027T3 (es) 1998-05-22 2010-10-22 The Board Of Trustees Of The Leland Stanford Junior University Moleculas bifuncionales y terapias basadas en las mismas.
GB0009607D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Medical compositions
GB0009592D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Respiratory combinations
HRP20010018A2 (en) 2001-01-09 2002-12-31 Pliva D D Novel anti-inflammatory compounds
GB0110411D0 (en) * 2001-04-27 2001-06-20 Astrazeneca Ab Chemical process
EP1465915A1 (en) * 2001-09-25 2004-10-13 PHARMACIA & UPJOHN COMPANY Stereoselective transacetalization of steroidal c-22 acetonide
BR0312634A (pt) 2002-07-08 2005-05-10 Pliva Istrazivacki Inst D O O Novos compostos, composições e métodos para tratamento de doenças e condições inflamatórias
ATE429441T1 (de) 2002-07-08 2009-05-15 Glaxosmithkline Zagreb Hybridmoleküle von makroliden mit steroidalen/nicht-steroidalen antientzündlich aktiven molekülen
US20040157810A1 (en) * 2002-08-23 2004-08-12 Teicher Martin H. Corticosteroid conjugates and uses thereof
TW200417371A (en) * 2003-02-21 2004-09-16 Upjohn Co A continuous process for the production of R-rofleponide
HRP20030324A2 (en) 2003-04-24 2005-02-28 Pliva-Istra�iva�ki institut d.o.o. Compounds of antiinflammatory effect
HRP20030604A2 (en) 2003-07-25 2005-04-30 Pliva-Istra�iva�ki institut d.o.o. Substituted furochromenes, preparation thereof andtheir antiinflammatory action
HRP20030603A2 (en) 2003-07-25 2005-10-31 Pliva-Istra�iva�ki institut d.o.o. Substituted furochromene compounds of antiinflammatory action
RU2007119577A (ru) 2004-10-27 2008-12-10 Глаксосмитклайн Истраживацки Центар Загреб Д.О.О. (Hr) Конъюгаты, обладающие противовоспалительной активностью
EP3827747A1 (en) 2005-04-28 2021-06-02 Otsuka Pharmaceutical Co., Ltd. Pharma-informatics system
US20080207577A1 (en) * 2005-07-11 2008-08-28 Astrazeneca Ab Combination I
EP1945240B1 (en) 2005-09-16 2016-12-28 Raptor Pharmaceutical Inc Compositions comprising receptor-associated protein (rap) variants specific for cr-containing proteins and uses thereof
WO2008100560A2 (en) * 2007-02-14 2008-08-21 University Of Southern California Estrogen receptor modulators, associated pharmaceutical compositions and methods of use
HUE059078T2 (hu) 2009-02-20 2022-10-28 Enhanx Biopharm Inc Glutation-alapú hatóanyagszállító rendszer
IL295075A (en) 2009-05-06 2022-09-01 Laboratory Skin Care Inc Preparations for administration through the skin that include complexes of an active substance with calcium phosphate and methods of using them

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3126375A (en) * 1964-03-24 Chioacyl
US3048581A (en) * 1960-04-25 1962-08-07 Olin Mathieson Acetals and ketals of 16, 17-dihydroxy steroids
US3357974A (en) * 1965-12-28 1967-12-12 Merck & Co Inc Processes for preparing 16alpha, 17alpha-acetals and ketals of 16alpha, 17alpha, 21-trihydroxy-delta4-pregnene-3, 20-diones
US3758686A (en) * 1971-12-07 1973-09-11 American Cyanamid Co Method of using steroid acetonides
SE378110B (fi) * 1972-05-19 1975-08-18 Bofors Ab
SE378109B (fi) * 1972-05-19 1975-08-18 Bofors Ab
SE8008524L (sv) * 1980-12-04 1982-06-05 Draco Ab 4-pregnen-derivat, ett forfarande for deras framstellning, beredning och metod for behandling av inflammatoriska tillstand
US4749649A (en) * 1983-05-16 1988-06-07 The Upjohn Company Microbial Δ1-dehydrogenation process using a scavenger of toxic oxygen
IT1196142B (it) * 1984-06-11 1988-11-10 Sicor Spa Procedimento per la preparazione di 16,17-acetali di derivati pregnanici e nuovi composti ottenuti
SE8403905D0 (sv) * 1984-07-30 1984-07-30 Draco Ab Liposomes and steroid esters
CN1060471A (zh) * 1985-04-04 1992-04-22 得拉科公司 新的16，17-缩醛取代雄甾烷-17β-酮类的制备方法
SE8604059D0 (sv) * 1986-09-25 1986-09-25 Astra Pharma Prod A method of controlling the epimeric distribution in the preparation of 16,17-acetals of pregnane derivatives
HU203562B (en) * 1989-03-09 1991-08-28 Richter Gedeon Vegyeszet Process for producing new steroide diols and pharmaceutical compositions containing them
HU203769B (en) * 1989-03-09 1991-09-30 Richter Gedeon Vegyeszet Process for producing new steroide derivatives and pharmaceutical compositions containing them
PL164294B1 (pl) * 1990-12-20 1994-07-29 Inst Farmaceutyczny Sposób otrzymywania diastereoizomeru /22R/-16a , 17a-butylidenodioksy-11 ß 21-dihydroksy-1,4-pregnadien-3,20-dionu PL
SE9100341D0 (sv) * 1991-02-04 1991-02-04 Astra Ab Novel steroids
SE9100342D0 (sv) * 1991-02-04 1991-02-04 Astra Ab Novel steroid esters

Also Published As

Publication number Publication date
SI9210065B (en) 2001-12-31
IS1601B (is) 1996-10-18
HUT64973A (en) 1994-03-28
AP9200353A0 (en) 1992-01-31
PT100086A (pt) 1994-05-31
AU1230792A (en) 1992-09-07
ATE178611T1 (de) 1999-04-15
EP0570454A1 (en) 1993-11-24
NO932761D0 (no) 1993-08-02
MA22406A1 (fr) 1992-10-01
SG52557A1 (en) 1998-09-28
PT100086B (pt) 1999-06-30
CN1140178A (zh) 1997-01-15
IS3808A (is) 1992-08-05
DE69228870D1 (de) 1999-05-12
US5939409A (en) 1999-08-17
PH31284A (en) 1998-07-06
EP0570454B1 (en) 1999-04-07
DZ1553A1 (fr) 2002-02-17
TNSN92007A1 (fr) 1993-06-08
CN1140059A (zh) 1997-01-15
SI9210065A (en) 1995-02-28
GR3030657T3 (en) 1999-10-29
CN1052155C (zh) 2000-05-10
CN1064079A (zh) 1992-09-02
IL100532A0 (en) 1992-09-06
HU218275B (en) 2000-07-28
CN1058724C (zh) 2000-11-22
AP366A (en) 1994-10-21
WO1992013872A1 (en) 1992-08-20
SK79693A3 (en) 1994-03-09
YU6592A (sh) 1995-01-31
CA2103924A1 (en) 1992-08-05
FI933450A0 (fi) 1993-08-03
RU2111212C1 (ru) 1998-05-20
US5674861A (en) 1997-10-07
SE9100341D0 (sv) 1991-02-04
SK281801B6 (sk) 2001-08-06
MX9200324A (es) 1992-09-01
YU48892B (sh) 2002-10-18
EE03111B1 (et) 1998-08-17
CZ281685B6 (cs) 1996-12-11
PL170000B1 (pl) 1996-10-31
NO932761L (no) 1993-08-02
CN1034868C (zh) 1997-05-14
DE69228870T2 (de) 1999-08-19
DK0570454T3 (da) 1999-10-18
KR100216720B1 (ko) 1999-10-01
UA41267C2 (uk) 2001-09-17
IE920166A1 (en) 1992-08-12
HU9302244D0 (en) 1993-10-28
NZ241210A (en) 1993-08-26
AU661471B2 (en) 1995-07-27
BG97971A (bg) 1994-04-29
CZ149693A3 (en) 1994-03-16
IL100532A (en) 1996-05-14
ES2133315T3 (es) 1999-09-16
ZA92233B (en) 1992-10-28
RO111195B1 (ro) 1996-07-30
HK1010733A1 (en) 1999-06-25
JPH06505232A (ja) 1994-06-16
BG62211B1 (bg) 1999-05-31
NO304073B1 (no) 1998-10-19

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