FI81784B - Nya 2-(4-klorfenyl)-3-cyklopropyl-1-(1h-1,2,4-triazol-1-yl)butan- 2-olderivat, deras framstaellning, vaextfungicida kompositioner innehaollande dessa och deras anvaendning. - Google Patents
Nya 2-(4-klorfenyl)-3-cyklopropyl-1-(1h-1,2,4-triazol-1-yl)butan- 2-olderivat, deras framstaellning, vaextfungicida kompositioner innehaollande dessa och deras anvaendning. Download PDFInfo
- Publication number
- FI81784B FI81784B FI840824A FI840824A FI81784B FI 81784 B FI81784 B FI 81784B FI 840824 A FI840824 A FI 840824A FI 840824 A FI840824 A FI 840824A FI 81784 B FI81784 B FI 81784B
- Authority
- FI
- Finland
- Prior art keywords
- formula
- compound
- chlorophenyl
- cyclopropyl
- triazol
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
- A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
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- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Environmental Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Pest Control & Pesticides (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Agronomy & Crop Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Claims (9)
1. Nya 2-(4-klorfenyl)-3-cyklopropyl-l-(1H-1,2,4-triazol-l-yl)butan-2-olderivat med formeln I 5 ί-N |l I) R oh \ oR2 9 /)—C1 (I) 10 j \L-7 CH-,-C — R~ A 15 väri R2 är H eller CH3, och R6 är H eller Cl, och etrar och estrar därav, i fri form eller i syraaddi-tionssaltform.
2. Förening enligt patenkravet 1, k ä n n e - t e c k n a d därav, att den är 2-(4-klorfenyl)-3-cyklo-20 propyl-1-(1H-1,2,4-triazol-l-yl)butan-2-ol.
3. Förening enligt patentkravet 2, känne-t e c k n a d därav, att den är i fri basform.
4. Förening enligt patentkravet 2, känne- t e c k n a d därav, att den är i syraadditionssaltform. 25 5. Förening enligt patentkravet 1, känne- t e c k n a d därav, att den är 2-(4-klorfenyl)-3-cyklo-propyl-3-metyl-l-(1H-1,2,4-triazol-l-yl)butan-2-ol.
6. Förfarande för framställning av en förening enligt nägot av patentkraven 1-5 med formeln I 30 1' J1 R6 n\n^ oh \ ci (i*
35 CH-,-C —R9 A 81 7b4 20 väri R2 är H eller CH3, och R6 är H eller Cl, och etrar och estrar därav, i fri form eller i syraaddi-tionssaltform, kännetecknat därav, att man läter en förening med formeln II Π .... M i vilken M är H, en metall eller en trialkylsilygrupp, 10 reagera med en förening med formeln III N /" " «i ζΓ
20 Cl väri R2 och R6 betecknar samma som i patentkravet 1, eller ett reaktivt funktionellt derivat därav, följt där sä önskas av företring eller förestring av den sälunda er-hällna etanolföreningen och utvinning av den sälunda er-25 hälinä föreningen i fri form eller i form av ett syraad-ditionssalt.
7. Växtfungicid komposition, känneteck-n a d därav, att den som aktiv komponent innefattar en förening med formeln I 30 n fi \\ R OH \_ N | /--\ ch2—c-Λ n—C1 (i)
35 CH3 9“R2 Δ II 81 7b4 21 väri R2 är H eller CH3, och R6 är H eller Cl, eller en eter eller ester därav, i fri form eller i agrikulturellt godtagbar syraadditionssaltform och ett agrikulturellt godtagbart spädningsmedel. 5 8. Sätt att bekämpa fytopatogena svampar, k ä n - netecknat därav, att man pä platsen därför appli-cerar en fungicidiskt verksam mängd av en förening med formeln I O -\ U-f-o-» ... CH0-C —R0 k väri Rj är H eller CH3 , och R6 är H eller Cl, eller en 20 eter eller ester därav, i fri form eller i agrikulturellt godtagbar syraadditionssaltform.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI896241A FI84176C (sv) | 1983-03-04 | 1989-12-22 | Förfarande för framställning av terapeutiskt aktiva 2-(4-klorfenyl)-3- cyklopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-olderivat |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1196/83A CH658654A5 (de) | 1983-03-04 | 1983-03-04 | Azolderivate, verfahren zu ihrer herstellung und mittel die diese verbindungen enthalten. |
| CH119683 | 1983-03-04 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI840824A0 FI840824A0 (fi) | 1984-03-01 |
| FI840824A FI840824A (fi) | 1984-09-05 |
| FI81784B true FI81784B (fi) | 1990-08-31 |
| FI81784C FI81784C (sv) | 1990-12-10 |
Family
ID=4204755
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI840824A FI81784C (sv) | 1983-03-04 | 1984-03-01 | Nya 2-(4-klorfenyl)-3-cyklopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-old erivat, deras framställning, växtfungicida kompositioner innehållande dessa och deras användning |
Country Status (35)
| Country | Link |
|---|---|
| US (2) | US4664696A (sv) |
| JP (1) | JPH06756B2 (sv) |
| AT (1) | AT387219B (sv) |
| AU (1) | AU571490B2 (sv) |
| BE (1) | BE899008A (sv) |
| BR (1) | BR8400958A (sv) |
| CA (1) | CA1232278A (sv) |
| CH (1) | CH658654A5 (sv) |
| CS (1) | CS251081B2 (sv) |
| DE (1) | DE3406993A1 (sv) |
| DK (1) | DK165407C (sv) |
| DZ (1) | DZ613A1 (sv) |
| EG (1) | EG16963A (sv) |
| ES (1) | ES8506642A1 (sv) |
| FI (1) | FI81784C (sv) |
| FR (1) | FR2542000B1 (sv) |
| GB (1) | GB2136423B (sv) |
| GR (1) | GR82344B (sv) |
| HU (1) | HU195907B (sv) |
| IE (1) | IE57003B1 (sv) |
| IL (1) | IL71126A (sv) |
| IT (1) | IT1199079B (sv) |
| KE (1) | KE3832A (sv) |
| LU (1) | LU85237A1 (sv) |
| MY (1) | MY8700767A (sv) |
| NL (1) | NL189564C (sv) |
| NZ (1) | NZ207359A (sv) |
| PH (1) | PH22915A (sv) |
| PL (1) | PL139662B1 (sv) |
| PT (1) | PT78192B (sv) |
| SE (1) | SE456678B (sv) |
| SU (1) | SU1416058A3 (sv) |
| TR (1) | TR22432A (sv) |
| UA (1) | UA7048A1 (sv) |
| ZA (1) | ZA841606B (sv) |
Families Citing this family (94)
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| CH658654A5 (de) * | 1983-03-04 | 1986-11-28 | Sandoz Ag | Azolderivate, verfahren zu ihrer herstellung und mittel die diese verbindungen enthalten. |
| NL8402548A (nl) * | 1983-09-01 | 1985-04-01 | Sandoz Ag | Nieuwe azoolverbindingen. |
| CH668772A5 (de) * | 1984-07-13 | 1989-01-31 | Sandoz Ag | 1,2,4-triazol-derivat, verfahren zu dessen herstellung und seine verwendung. |
| EP0180850A3 (de) * | 1984-11-02 | 1987-05-27 | Bayer Ag | Antimykotische Azolylmethyl-cyclopropyl-carbinol Derivate |
| CN1008735B (zh) * | 1984-11-02 | 1990-07-11 | 拜尔公司 | 以取代的氮杂茂基甲基-环丙基-甲醇衍生物为活性成分的组合物 |
| GB8429932D0 (en) * | 1984-11-27 | 1985-01-03 | Pfizer Ltd | Triazole antifungal agents |
| GB8614367D0 (en) * | 1986-06-12 | 1986-07-16 | Sandoz Ltd | Fungicides |
| GB8617780D0 (en) * | 1986-07-21 | 1986-08-28 | Sandoz Ltd | Fungicides |
| GB8629360D0 (en) * | 1986-12-09 | 1987-01-21 | Sandoz Ltd | Fungicides |
| DE3800094C2 (de) * | 1987-01-14 | 1998-05-14 | Ciba Geigy Ag | Verfahren und hydrophobe Zubereitung zur Bekämpfung von Schnittwundparasiten bei Pflanzen |
| FR2609368B1 (fr) * | 1987-01-14 | 1990-04-13 | Sandoz Sa Produits | Utilisation de derives du 1, 2, 4-triazole pour combattre les maladies de plaies de taille des plantes perennes |
| CA1304938C (en) * | 1987-03-19 | 1992-07-14 | Tsugio Kawahara | Display apparatus for an automatic vending machine |
| DE3732388A1 (de) * | 1987-09-25 | 1989-04-06 | Bayer Ag | Azolylmethylcyclopropyl-carbinole enthaltende antimykotische mittel |
| DE3732387A1 (de) * | 1987-09-25 | 1989-04-06 | Bayer Ag | Azolylmethylcyclopropyl-derivate enthaltende antimykotische mittel |
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| BR102013027313B1 (pt) * | 2013-10-23 | 2019-06-18 | Iharabras S.A. Indústrias Químicas | Processo para a preparação seletiva de (1h-1,2,4-triazol-1-il) alcanóis, composto hidrazinil alcanol obtido por tal processo e seu uso |
| AU2015238666B2 (en) * | 2014-03-26 | 2018-11-15 | Basf Se | Substituted [1,2,4]triazole and imidazole compounds as fungicides |
| EP2979549A1 (en) | 2014-07-31 | 2016-02-03 | Basf Se | Method for improving the health of a plant |
| JP2017538860A (ja) | 2014-10-24 | 2017-12-28 | ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ | 固体粒子の表面荷電を改変するための、非両性の四級化可能な水溶性ポリマー |
| CN105777508B (zh) * | 2014-12-22 | 2019-01-25 | 上海泰禾国际贸易有限公司 | 一种1-(4-氯苯基)-2-环丙基-1-丙酮的合成方法 |
| EP2910126A1 (en) | 2015-05-05 | 2015-08-26 | Bayer CropScience AG | Active compound combinations having insecticidal properties |
| AU2016287098A1 (en) | 2015-07-02 | 2018-01-25 | BASF Agro B.V. | Pesticidal compositions comprising a triazole compound |
| US11185548B2 (en) | 2016-12-23 | 2021-11-30 | Helmholtz Zentrum Munchen—Deutsches Forschungszentrum Für Gesundheit Und Umwelt (Gmbh) | Inhibitors of cytochrome P450 family 7 subfamily B member 1 (CYP7B1) for use in treating diseases |
| CN109020905B (zh) * | 2017-06-09 | 2022-12-23 | 华东理工大学 | 两种环丙唑醇的多晶型及其制备方法 |
| MX2020014203A (es) | 2018-06-21 | 2021-05-27 | Yumanity Therapeutics Inc | Composiciones y métodos para el tratamiento y la prevención de trastornos neurológicos. |
| CN109006836A (zh) * | 2018-10-10 | 2018-12-18 | 江苏七洲绿色化工股份有限公司 | 一种含有环丙唑醇的干悬浮剂及其制备方法 |
| US20220332691A1 (en) | 2019-09-12 | 2022-10-20 | Saltigo Gmbh | Improved process for preparing epoxides from aldehydes or ketones |
| CA3153838A1 (en) | 2019-09-12 | 2021-03-18 | Saltigo Gmbh | Improved process for preparing cyclopropyl compounds from alkenes |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4654332A (en) * | 1979-03-07 | 1987-03-31 | Imperial Chemical Industries Plc | Heterocyclic compounds |
| EP0023103A1 (en) * | 1979-07-04 | 1981-01-28 | Pfizer Limited | Antifungal imidazole derivatives, process for their preparation and pharmaceutical compositions thereof |
| US4414210A (en) * | 1979-10-02 | 1983-11-08 | Rohm And Haas Company | 2-Hydroxyarylethyltriazole fungicides |
| DE3042303A1 (de) * | 1979-11-13 | 1981-08-27 | Sandoz-Patent-GmbH, 7850 Lörrach | Organische verbindungen, deren herstellung und verwendung |
| CH647513A5 (de) * | 1979-11-13 | 1985-01-31 | Sandoz Ag | Triazol-derivate, deren herstellung und verwendung. |
| US4366401A (en) * | 1979-12-01 | 1982-12-28 | Lucas Industries Limited | Electromagnetic devices |
| US4432989A (en) * | 1980-07-18 | 1984-02-21 | Sandoz, Inc. | αAryl-1H-imidazole-1-ethanols |
| DE3177275D1 (de) * | 1980-08-18 | 1992-04-16 | Ici Plc | Verwendung von triazolylaethanol-derivate und deren zusammensetzungen als nichtlandwirtschaftliche fungizide. |
| ZA815700B (en) * | 1980-08-28 | 1982-08-25 | Ici Ltd | Pharmaceutical compositions |
| DE3175673D1 (en) * | 1980-11-19 | 1987-01-15 | Ici Plc | Triazole compounds, a process for preparing them, their use as plant fungicides and fungicidal compositions containing them |
| EP0117578A3 (en) * | 1983-02-23 | 1985-01-30 | Shionogi & Co., Ltd. | Azole-substituted alcohol derivatives |
| CH658654A5 (de) * | 1983-03-04 | 1986-11-28 | Sandoz Ag | Azolderivate, verfahren zu ihrer herstellung und mittel die diese verbindungen enthalten. |
| NL8402548A (nl) * | 1983-09-01 | 1985-04-01 | Sandoz Ag | Nieuwe azoolverbindingen. |
-
1983
- 1983-03-04 CH CH1196/83A patent/CH658654A5/de not_active IP Right Cessation
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1984
- 1984-02-20 NL NLAANVRAGE8400529,A patent/NL189564C/xx not_active IP Right Cessation
- 1984-02-20 HU HU84655A patent/HU195907B/hu unknown
- 1984-02-27 US US06/584,161 patent/US4664696A/en not_active Expired - Lifetime
- 1984-02-27 FR FR8403095A patent/FR2542000B1/fr not_active Expired
- 1984-02-27 DE DE19843406993 patent/DE3406993A1/de active Granted
- 1984-02-27 BE BE1/10967A patent/BE899008A/fr not_active IP Right Cessation
- 1984-02-29 BR BR8400958A patent/BR8400958A/pt not_active IP Right Cessation
- 1984-02-29 DK DK149684A patent/DK165407C/da not_active IP Right Cessation
- 1984-02-29 GB GB08405226A patent/GB2136423B/en not_active Expired
- 1984-03-01 FI FI840824A patent/FI81784C/sv not_active IP Right Cessation
- 1984-03-01 ES ES530203A patent/ES8506642A1/es not_active Expired
- 1984-03-02 AT AT0071684A patent/AT387219B/de not_active IP Right Cessation
- 1984-03-02 SU SU843707140A patent/SU1416058A3/ru active
- 1984-03-02 IE IE508/84A patent/IE57003B1/en not_active IP Right Cessation
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- 1984-03-02 JP JP59041207A patent/JPH06756B2/ja not_active Expired - Lifetime
- 1984-03-02 UA UA3707140A patent/UA7048A1/uk unknown
- 1984-03-02 PL PL1984246493A patent/PL139662B1/pl unknown
- 1984-03-02 CA CA000448704A patent/CA1232278A/en not_active Expired
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- 1984-03-02 TR TR1540/84A patent/TR22432A/xx unknown
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- 1984-03-02 LU LU85237A patent/LU85237A1/fr unknown
- 1984-03-02 CS CS841536A patent/CS251081B2/cs unknown
- 1984-03-02 IT IT47791/84A patent/IT1199079B/it active
- 1984-03-02 PT PT78192A patent/PT78192B/pt unknown
- 1984-03-02 AU AU25253/84A patent/AU571490B2/en not_active Expired
- 1984-03-02 SE SE8401177A patent/SE456678B/sv not_active IP Right Cessation
- 1984-03-03 EG EG149/84A patent/EG16963A/xx active
- 1984-03-09 DZ DZ847095A patent/DZ613A1/fr active
- 1984-03-21 GR GR74167A patent/GR82344B/el unknown
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1987
- 1987-03-20 US US07/028,453 patent/US4849439A/en not_active Expired - Lifetime
- 1987-12-30 MY MY767/87A patent/MY8700767A/xx unknown
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1988
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| PC | Transfer of assignment of patent |
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