FI66619C - Foerfarande foer framstaellning av farmaceutiskt anvaendbara 7beta-(d-2-amino-2-(laogalkylsulfonylaminofenyl)-asetylamino)-3-r-3-cefem-4-karboxylsyror - Google Patents

Foerfarande foer framstaellning av farmaceutiskt anvaendbara 7beta-(d-2-amino-2-(laogalkylsulfonylaminofenyl)-asetylamino)-3-r-3-cefem-4-karboxylsyror Download PDF

Info

Publication number
FI66619C
FI66619C FI762381A FI762381A FI66619C FI 66619 C FI66619 C FI 66619C FI 762381 A FI762381 A FI 762381A FI 762381 A FI762381 A FI 762381A FI 66619 C FI66619 C FI 66619C
Authority
FI
Finland
Prior art keywords
amino
cephem
group
acid
acetylamino
Prior art date
Application number
FI762381A
Other languages
English (en)
Finnish (fi)
Other versions
FI762381A (ko
FI66619B (fi
Inventor
Rene Wiederkehr
Hans Bickel
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI762381A publication Critical patent/FI762381A/fi
Publication of FI66619B publication Critical patent/FI66619B/fi
Application granted granted Critical
Publication of FI66619C publication Critical patent/FI66619C/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
FI762381A 1975-08-20 1976-08-19 Foerfarande foer framstaellning av farmaceutiskt anvaendbara 7beta-(d-2-amino-2-(laogalkylsulfonylaminofenyl)-asetylamino)-3-r-3-cefem-4-karboxylsyror FI66619C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1082275A CH622802A5 (ko) 1975-08-20 1975-08-20
CH1082275 1975-08-20

Publications (3)

Publication Number Publication Date
FI762381A FI762381A (ko) 1977-02-21
FI66619B FI66619B (fi) 1984-07-31
FI66619C true FI66619C (fi) 1984-11-12

Family

ID=4367199

Family Applications (1)

Application Number Title Priority Date Filing Date
FI762381A FI66619C (fi) 1975-08-20 1976-08-19 Foerfarande foer framstaellning av farmaceutiskt anvaendbara 7beta-(d-2-amino-2-(laogalkylsulfonylaminofenyl)-asetylamino)-3-r-3-cefem-4-karboxylsyror

Country Status (35)

Country Link
US (1) US4069324A (ko)
JP (1) JPS5225794A (ko)
AR (2) AR215247A1 (ko)
AT (1) AT348119B (ko)
AU (1) AU501362B2 (ko)
BE (1) BE845320A (ko)
BG (5) BG27558A3 (ko)
CA (1) CA1090331A (ko)
CH (5) CH622802A5 (ko)
CS (6) CS193584B2 (ko)
CY (1) CY1165A (ko)
DD (1) DD127142A5 (ko)
DE (1) DE2636962A1 (ko)
DK (1) DK374576A (ko)
ES (1) ES450775A1 (ko)
FI (1) FI66619C (ko)
FR (1) FR2321293A1 (ko)
GB (1) GB1551931A (ko)
GR (1) GR61656B (ko)
HK (1) HK12083A (ko)
HU (1) HU179140B (ko)
IE (1) IE43717B1 (ko)
IL (1) IL50298A (ko)
MY (1) MY8400030A (ko)
NL (1) NL7609240A (ko)
NO (1) NO152510C (ko)
NZ (1) NZ181804A (ko)
OA (1) OA05419A (ko)
PH (1) PH12931A (ko)
PL (4) PL108107B1 (ko)
PT (1) PT65494B (ko)
RO (7) RO69463A (ko)
SE (1) SE437990B (ko)
SU (7) SU847923A3 (ko)
ZA (1) ZA764980B (ko)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5498489U (ko) * 1977-12-22 1979-07-11
JPS5418379U (ko) * 1978-08-14 1979-02-06
JPS57140307U (ko) * 1981-02-27 1982-09-02
SE438477B (sv) * 1983-02-28 1985-04-22 Gote Hakansson Anordning vid vagnar
US4927943A (en) * 1984-09-04 1990-05-22 Bristol-Myers Company Substituted 7-oxomitosanes
CN1130908A (zh) * 1994-07-22 1996-09-11 安蒂比奥蒂科斯公司 戊二酸单酰基7-氨基头孢烷酸衍生物及其制备方法
CN103387584B (zh) * 2013-07-17 2015-02-25 盐城开元医药化工有限公司 一种7-氨基-3-氯-3-头孢环-4-羧酸的合成方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR206201A1 (es) * 1972-06-29 1976-07-07 Ciba Geigy Ag Procedimiento para la obtencion de compuestos de acido 7beta-amino-3-cefem-3-01-4-carboxilico0-substituidos
US3917587A (en) * 1972-11-28 1975-11-04 Lilly Co Eli Cephalosporin ethers
US3925372A (en) * 1973-02-23 1975-12-09 Lilly Co Eli Alpha-aminoacyl-3-halo cephalosporins
AR208068A1 (es) * 1973-02-23 1976-11-30 Lilly Co Eli Un procedimiento para preparar derivados de acidos 7-acilamido-3-halo-cefem-4-carboxilico los esteres y las sales farmaceuticamente aceptables de los mismos
YU36970B (en) * 1973-02-23 1984-08-31 Lilly Co Eli Process for obtaining 7-(amino)-acylamido-3-halocephalosporins
AR205537A1 (es) * 1973-05-10 1976-05-14 Fujisawa Pharmaceutical Co Procedimiento para la preparacion de derivados de acido 7-substituido fenilglicinamido - 3 - substituido - 3 - cefem - 4 - carboxilicos
US3994887A (en) * 1973-05-17 1976-11-30 Recherche Et Industrie Therapeutiques (R.I.T.) 7-(3-Substituted ureido) cephalosporins
SE7408898L (ko) * 1973-07-06 1975-01-07 Fujisawa Pharmaceutical Co
US3998819A (en) * 1973-12-26 1976-12-21 Smithkline Corporation Trifluoroethyl-mercapto, -sulfinyl or -sulfonyl acetamidocephalosporins
US3985746A (en) * 1975-03-25 1976-10-12 E. R. Squibb & Sons, Inc. 7-(α-Cyanomethylthio)acetamido-3-cephem carboxylates
US4008230A (en) * 1975-10-29 1977-02-15 Eli Lilly And Company Process for preparing 3-hydroxy cephalosporins

Also Published As

Publication number Publication date
FI762381A (ko) 1977-02-21
PL108059B1 (pl) 1980-03-31
PL108107B1 (pl) 1980-03-31
PT65494A (en) 1976-09-01
BE845320A (fr) 1977-02-21
PH12931A (en) 1979-10-17
NO762864L (ko) 1977-02-22
SU670224A3 (ru) 1979-06-25
SE7609222L (sv) 1977-02-21
SU719505A3 (ru) 1980-02-29
MY8400030A (en) 1984-12-31
AU501362B2 (en) 1979-06-21
BG27561A3 (bg) 1979-11-12
PL110876B1 (en) 1980-08-30
OA05419A (fr) 1981-03-31
HU179140B (en) 1982-08-28
NO152510C (no) 1985-10-09
GB1551931A (en) 1979-09-05
DK374576A (da) 1977-02-21
SE437990B (sv) 1985-03-25
PT65494B (en) 1978-02-13
CS193584B2 (en) 1979-10-31
CH622805A5 (ko) 1981-04-30
CA1090331A (en) 1980-11-25
FR2321293A1 (fr) 1977-03-18
JPS5225794A (en) 1977-02-25
IE43717L (en) 1977-02-20
BG27561A4 (en) 1979-11-12
SU715029A3 (ru) 1980-02-05
ATA615476A (de) 1978-06-15
CS193560B2 (en) 1979-10-31
CS193586B2 (en) 1979-10-31
CS193585B2 (en) 1979-10-31
DD127142A5 (ko) 1977-09-07
CH622802A5 (ko) 1981-04-30
NZ181804A (en) 1978-04-28
ZA764980B (en) 1977-07-27
GR61656B (en) 1978-12-05
US4069324A (en) 1978-01-17
PL191915A1 (pl) 1978-10-23
IE43717B1 (en) 1981-05-06
BG27559A4 (en) 1979-11-12
RO74667A (ro) 1980-10-30
RO75411A (ro) 1980-11-30
RO74668A (ro) 1980-10-30
FI66619B (fi) 1984-07-31
CH622804A5 (ko) 1981-04-30
CH622806A5 (ko) 1981-04-30
AU1698576A (en) 1978-02-23
AR215247A1 (es) 1979-09-28
IL50298A0 (en) 1976-10-31
RO75071A (ro) 1980-10-30
SU680650A3 (ru) 1979-08-15
NL7609240A (nl) 1977-02-22
RO69463A (ro) 1980-08-15
IL50298A (en) 1979-05-31
NO152510B (no) 1985-07-01
PL110983B1 (en) 1980-08-30
DE2636962C2 (ko) 1987-07-02
RO74687A (ro) 1980-10-30
SU803862A3 (ru) 1981-02-07
RO75412A (ro) 1980-12-30
CY1165A (en) 1983-06-10
CH622803A5 (ko) 1981-04-30
DE2636962A1 (de) 1977-03-03
CS193589B2 (en) 1979-10-31
AT348119B (de) 1979-01-25
SU847923A3 (ru) 1981-07-15
AR214791A1 (es) 1979-07-31
SU719506A3 (ru) 1980-02-29
CS193588B2 (en) 1979-10-31
BG27558A3 (en) 1979-11-12
JPS6152158B2 (ko) 1986-11-12
BG27560A4 (en) 1979-11-12
ES450775A1 (es) 1977-10-01
HK12083A (en) 1983-04-07
FR2321293B1 (ko) 1979-01-12

Similar Documents

Publication Publication Date Title
FI60870C (fi) Foerfarande foer framstaellning av farmakologiskt vaerdefulla o-substituerade 7beta-amino-3-cefem-3-ol-4-karbonsyrafoereningar
US4201782A (en) Thiadiazolyl cephalosporin analogs
US3992377A (en) 3-Thio-substituted cephalosporin antibiotics
FI66389B (fi) Foerfarande foer framstaellning av 7beta-amino-2- eller -3-cefem-3-ol-4-karboxylsyrafoereningar
US4254119A (en) 3-Unsubstituted-3-cephem compounds
SE445644B (sv) 7beta-amino-3-cefem-3-amino-4-karbonsyra-foreningar som mellanprodukter for framstellning av 7beta-amino-3-cefem-3-ol-4-karbonsyra-foreningar
NO800239L (no) Fremgangsmaate ved fremstilling av derivater av 7-acylamino-3-cepham-4-karboksylsyre
FI66619C (fi) Foerfarande foer framstaellning av farmaceutiskt anvaendbara 7beta-(d-2-amino-2-(laogalkylsulfonylaminofenyl)-asetylamino)-3-r-3-cefem-4-karboxylsyror
US3983113A (en) Cephalosporin type antibacterials
Crowell et al. 3-Sulfonyl-1-carba-1-dethiacephems
EP0107928B1 (en) Vinylthioacetamido oxacephalosporin derivatives, and intermediates therefor, their preparation, formulations containing the same and their antibacterial use
US3966719A (en) 4-(Tetrazol-5-yl)-Δ3 -cephem compounds
Wheeler et al. Orally active esters of cephalosporin antibiotics. 3. Synthesis and biological properties of aminoacyloxymethyl esters of 7-[D-(-)-mandelamido]-3-[[(1-methyl-1H-tetrazol-5-yl) thio] methyl]-3-cephem-4-carboxylic acid
JPS59231090A (ja) フルオロメチルチオオキサセフアロスポリン
US4614797A (en) Cephalosporin hydroxamic acids
KR870000528B1 (ko) 3-아지도 세팔로스포린의 제조방법
IE47929B1 (en) Substituted imidazolidinyl-3-chloro-3-cephem-4-carboxylic acids
EP0122156A2 (en) Improvements in or relating to benzothienylglycyl cephalosporin derivatives
EP0219926A2 (en) Cephalosporins, processes for their preparation and pharmaceutical compositions containing them
US4837215A (en) Penem derivatives
JP3914276B2 (ja) 新規なセファロスポリン誘導体またはその塩
JPS5924158B2 (ja) 抗菌剤の製法
KR840000406B1 (ko) 세팔로스포린의 제조방법
JPS594437B2 (ja) ３−ハロゲノ−３−セフエム−４−カルボン酸またはその塩の製法およびこれら化合物を含む医薬用配合物
Barth et al. 4-(Tetrazol-5-yl)-Δ3-cephem compounds

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: CIBA-GEIGY AG