FI47099B - - Google Patents

Info

Publication number
FI47099B
FI47099B FI257270A FI257270A FI47099B FI 47099 B FI47099 B FI 47099B FI 257270 A FI257270 A FI 257270A FI 257270 A FI257270 A FI 257270A FI 47099 B FI47099 B FI 47099B
Authority
FI
Finland
Application number
FI257270A
Other languages
Finnish (fi)
Other versions
FI47099C (fi
Inventor
Gal Georges
Sletzinger Meyer
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of FI47099B publication Critical patent/FI47099B/fi
Publication of FI47099C publication Critical patent/FI47099C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/36—Oxygen atoms in position 3, e.g. adrenochrome

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI257270A 1963-02-01 1970-09-21 Menetelmä 1-p-klooribentsoyyli-2-metyyli-5-metoksi-3-indolyylietikkaha pon valmistamiseksi, jolla on tulehdusta estävä, antipyreettinen ja an algeettinen vaikutus. FI47099C (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25564263A 1963-02-01 1963-02-01

Publications (2)

Publication Number Publication Date
FI47099B true FI47099B (ja) 1973-05-31
FI47099C FI47099C (fi) 1973-09-10

Family

ID=22969254

Family Applications (9)

Application Number Title Priority Date Filing Date
FI16964A FI46955C (fi) 1963-02-01 1964-01-29 Menetelmä terapeuttisesti vaikuttavan 1-p-klooribentsoyyli-2-alempi-al kyyli-5-alempi-alkoksi-3-indolyyli-etikkahapon valmistamiseksi
FI702570A FI47097C (fi) 1963-02-01 1970-09-21 Menetelmä terapeuttisesti vaikuttavan 1-p-klooribentsoyyli-2-metyyli-5 -metoksi-3-indolyylietikkahapon valmistamiseksi.
FI257570A FI47101C (fi) 1963-02-01 1970-09-21 Menetelmä terapeuttisesti vaikuttavien alfa-(3-indolyyli)-alempien-ali faattisten happojen valmistamiseksi.
FI257070A FI47097B (ja) 1963-02-01 1970-09-21
FI257270A FI47099C (fi) 1963-02-01 1970-09-21 Menetelmä 1-p-klooribentsoyyli-2-metyyli-5-metoksi-3-indolyylietikkaha pon valmistamiseksi, jolla on tulehdusta estävä, antipyreettinen ja an algeettinen vaikutus.
FI257170A FI47098C (fi) 1963-02-01 1970-09-21 Menetelmä 1-p-klooribentsoyyli-2-metyyli-5-metoksi-3-indolyyliasetalde hydin valmistamiseksi, jolla on tulehdusta estävä, antipyreettinen ja analgeettinen vaikutus.
FI257370A FI47185C (fi) 1963-02-01 1970-09-21 Menetelmä 1-p-klooribentsoyyli-2-metyyli-5-metoksi-indoli-3-etanolin v almistamiseksi, jolla on tulehdusta estävä, antipyreettinen ja anlgeet tinen vaikutus.
FI257470A FI47100C (fi) 1963-02-01 1970-09-21 Menetelmä terapeuttisesti vaikuttavien 1-p-klooribentsoyyli-2-alempi-a lkyyli-5-alempi-alkoksi-3-indolyyli-etikkahapon valmistamiseksi.
FI256870A FI47096C (fi) 1963-02-01 1970-09-21 Menetelmä terapeuttisesti vaikuttavien alfa-(3-indolyyli)-alempien-ali faattisten happojen tert.-butyyliesterin valmistamiseksi.

Family Applications Before (4)

Application Number Title Priority Date Filing Date
FI16964A FI46955C (fi) 1963-02-01 1964-01-29 Menetelmä terapeuttisesti vaikuttavan 1-p-klooribentsoyyli-2-alempi-al kyyli-5-alempi-alkoksi-3-indolyyli-etikkahapon valmistamiseksi
FI702570A FI47097C (fi) 1963-02-01 1970-09-21 Menetelmä terapeuttisesti vaikuttavan 1-p-klooribentsoyyli-2-metyyli-5 -metoksi-3-indolyylietikkahapon valmistamiseksi.
FI257570A FI47101C (fi) 1963-02-01 1970-09-21 Menetelmä terapeuttisesti vaikuttavien alfa-(3-indolyyli)-alempien-ali faattisten happojen valmistamiseksi.
FI257070A FI47097B (ja) 1963-02-01 1970-09-21

Family Applications After (4)

Application Number Title Priority Date Filing Date
FI257170A FI47098C (fi) 1963-02-01 1970-09-21 Menetelmä 1-p-klooribentsoyyli-2-metyyli-5-metoksi-3-indolyyliasetalde hydin valmistamiseksi, jolla on tulehdusta estävä, antipyreettinen ja analgeettinen vaikutus.
FI257370A FI47185C (fi) 1963-02-01 1970-09-21 Menetelmä 1-p-klooribentsoyyli-2-metyyli-5-metoksi-indoli-3-etanolin v almistamiseksi, jolla on tulehdusta estävä, antipyreettinen ja anlgeet tinen vaikutus.
FI257470A FI47100C (fi) 1963-02-01 1970-09-21 Menetelmä terapeuttisesti vaikuttavien 1-p-klooribentsoyyli-2-alempi-a lkyyli-5-alempi-alkoksi-3-indolyyli-etikkahapon valmistamiseksi.
FI256870A FI47096C (fi) 1963-02-01 1970-09-21 Menetelmä terapeuttisesti vaikuttavien alfa-(3-indolyyli)-alempien-ali faattisten happojen tert.-butyyliesterin valmistamiseksi.

Country Status (11)

Country Link
AT (1) AT277992B (ja)
BE (1) BE643268A (ja)
BR (1) BR6456479D0 (ja)
CH (16) CH457435A (ja)
DE (16) DE1695492A1 (ja)
DK (11) DK109334C (ja)
FI (9) FI46955C (ja)
FR (1) FR1559559A (ja)
GB (13) GB1050738A (ja)
NL (1) NL6400813A (ja)
SE (12) SE302463B (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU163233B (ja) * 1970-07-31 1973-07-28
DE58902127D1 (de) * 1988-06-21 1992-10-01 Rauter Vita Zahnfabrik Dispergierte keramikmasse.
GB9518994D0 (en) * 1995-09-16 1995-11-15 Agrevo Uk Ltd Fungicides

Also Published As

Publication number Publication date
DK113501B (da) 1969-03-31
FI47099C (fi) 1973-09-10
DE1695487A1 (de) 1970-10-01
FI47101B (ja) 1973-05-31
CH466283A (de) 1968-12-15
FI47097B (ja) 1973-05-31
DK109514C (da) 1968-05-06
FI47101C (fi) 1973-09-10
DE1770134A1 (de) 1971-09-30
CH466288A (de) 1968-12-15
SE317975B (ja) 1969-12-01
FI47100C (fi) 1973-09-10
GB1050733A (ja)
DE1770116A1 (de) 1971-10-14
GB1050735A (ja)
GB1050728A (ja)
FI46955B (ja) 1973-05-02
SE302463B (ja) 1968-07-22
SE320666B (ja) 1970-02-16
GB1050740A (ja)
SE304995B (ja) 1968-10-14
DE1470059B1 (de) 1970-01-29
DK109334C (da) 1968-04-16
FI47096B (ja) 1973-05-31
FR1559559A (ja) 1969-03-14
SE302131B (ja) 1968-07-08
FI47098C (fi) 1973-09-10
CH457436A (de) 1968-06-15
CH457437A (de) 1968-06-15
DK112447B (da) 1968-12-16
CH457434A (de) 1968-06-15
DE1695488A1 (de) 1970-09-17
CH557815A (de) 1975-01-15
BR6456479D0 (pt) 1973-09-20
NL6400813A (ja) 1964-08-03
SE320069B (ja) 1970-02-02
DE1770802A1 (de) 1972-02-17
DK112239B (da) 1968-11-25
SE307948B (ja) 1969-01-27
SE320367B (ja) 1970-02-09
CH466286A (de) 1968-12-15
CH457435A (de) 1968-06-15
SE302133B (sv) 1968-07-08
FI47100B (ja) 1973-05-31
AT277992B (de) 1970-01-12
DK112446B (da) 1968-12-16
DK112238B (da) 1968-11-25
GB1050739A (ja)
GB1050729A (ja)
GB1050731A (ja)
FI47096C (fi) 1973-09-10
CH464202A (de) 1968-10-31
CH466289A (de) 1968-12-15
CH466284A (de) 1968-12-15
DK111751B (da) 1968-10-07
DE1695490A1 (de) 1971-04-15
FI47185C (fi) 1973-10-10
DE1695493A1 (de) 1971-04-01
DK109562C (da) 1968-05-13
CH466287A (de) 1968-12-15
DK112314B (da) 1968-12-02
DE1695491A1 (de) 1971-04-15
SE307133B (ja) 1968-12-23
DE1793561A1 (de) 1972-01-20
DE1695492A1 (de) 1971-04-01
FI47097C (fi) 1973-09-10
DE1695484A1 (de) 1971-04-15
GB1050737A (ja)
GB1050734A (ja)
GB1050736A (ja)
CH464203A (de) 1968-10-31
GB1050730A (ja)
CH466285A (de) 1968-12-15
DK112313B (da) 1968-12-02
CH466290A (de) 1968-12-15
FI47185B (ja) 1973-07-02
DE1695489A1 (de) 1970-08-13
CH489495A (de) 1970-04-30
BE643268A (ja) 1964-07-31
GB1050738A (ja)
DE1695485A1 (de) 1971-04-15
SE302130B (sv) 1968-07-08
FI46955C (fi) 1973-08-10
DE1695486A1 (de) 1971-04-15
DE1770132A1 (de) 1971-09-30
FI47098B (ja) 1973-05-31
GB1050732A (ja)
SE302132B (sv) 1968-07-08

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