FI116623B - Menetelmä uusien terapeuttisesti käyttökelpoisten fenyyli-indoliyhdisteiden valmistamiseksi - Google Patents
Menetelmä uusien terapeuttisesti käyttökelpoisten fenyyli-indoliyhdisteiden valmistamiseksi Download PDFInfo
- Publication number
- FI116623B FI116623B FI961844A FI961844A FI116623B FI 116623 B FI116623 B FI 116623B FI 961844 A FI961844 A FI 961844A FI 961844 A FI961844 A FI 961844A FI 116623 B FI116623 B FI 116623B
- Authority
- FI
- Finland
- Prior art keywords
- ethyl
- chloro
- fluorophenyl
- indol
- piperidin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Sewing Machines And Sewing (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Polyurethanes Or Polyureas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK123493 | 1993-11-01 | ||
| DK931234A DK123493D0 (da) | 1993-11-01 | 1993-11-01 | Compounds |
| PCT/DK1994/000407 WO1995012591A1 (en) | 1993-11-01 | 1994-10-28 | Phenylindole compounds |
| DK9400407 | 1994-10-28 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI961844A0 FI961844A0 (fi) | 1996-04-30 |
| FI961844A FI961844A (fi) | 1996-04-30 |
| FI116623B true FI116623B (fi) | 2006-01-13 |
Family
ID=8102507
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI961844A FI116623B (fi) | 1993-11-01 | 1996-04-30 | Menetelmä uusien terapeuttisesti käyttökelpoisten fenyyli-indoliyhdisteiden valmistamiseksi |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US5703087A (ko) |
| EP (1) | EP0726898B1 (ko) |
| JP (1) | JP3898219B2 (ko) |
| KR (1) | KR100350550B1 (ko) |
| CN (1) | CN1134149A (ko) |
| AT (1) | ATE198199T1 (ko) |
| AU (1) | AU683700B2 (ko) |
| CA (1) | CA2175498C (ko) |
| CZ (1) | CZ291403B6 (ko) |
| DE (1) | DE69426462T2 (ko) |
| DK (2) | DK123493D0 (ko) |
| ES (1) | ES2154303T3 (ko) |
| FI (1) | FI116623B (ko) |
| GR (1) | GR3035462T3 (ko) |
| HK (1) | HK1013817A1 (ko) |
| HU (1) | HUT76063A (ko) |
| IL (2) | IL111395A (ko) |
| LV (1) | LV12805B (ko) |
| NO (1) | NO309038B1 (ko) |
| NZ (1) | NZ275086A (ko) |
| PL (1) | PL176391B1 (ko) |
| PT (1) | PT726898E (ko) |
| RU (1) | RU2156249C2 (ko) |
| SI (1) | SI0726898T1 (ko) |
| SK (1) | SK281761B6 (ko) |
| WO (1) | WO1995012591A1 (ko) |
| ZA (1) | ZA948589B (ko) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6489341B1 (en) | 1999-06-02 | 2002-12-03 | Sepracor Inc. | Methods for the treatment of neuroleptic and related disorders using sertindole derivatives |
| JP2003509509A (ja) * | 1999-09-09 | 2003-03-11 | ハー・ルンドベック・アクチエゼルスカベット | ５−アミノアルキル及び５−アミノカルボニル置換されたインドール類 |
| US20070212412A1 (en) * | 2005-09-08 | 2007-09-13 | H. Lundbeck A/S | Stable solid formulation of sertindole |
| TW200821296A (en) * | 2006-06-01 | 2008-05-16 | Lundbeck & Co As H | Use of sertindole for the preventive treatment of suicidal behaviour |
| ES2575215T3 (es) * | 2009-12-11 | 2016-06-27 | Autifony Therapeutics Limited | Derivados de imidazolidindiona |
| JP5860042B2 (ja) * | 2010-06-16 | 2016-02-16 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | 置換５、６及び７員複素環、そのような化合物を含有する医薬及びそれらの使用 |
| JP5913357B2 (ja) | 2010-12-06 | 2016-04-27 | アウトイフオンイ トヘラペウトイクス リミテッド | Ｋｖ３阻害剤として有用なヒダントイン誘導体 |
| EP2718285B1 (en) * | 2011-06-07 | 2016-03-16 | Autifony Therapeutics Limited | Hydantoin derivatives as kv3 inhibitors |
| EP2788339B1 (en) * | 2011-12-06 | 2016-03-09 | Autifony Therapeutics Limited | Hydantoin derivatives useful as kv3 inhibitors |
| JP2015517563A (ja) | 2012-05-22 | 2015-06-22 | アウトイフオンイ トヘラペウトイクス リミテッド | Ｋｖ３阻害剤としてのヒダントイン誘導体 |
| JP6240667B2 (ja) | 2012-05-22 | 2017-11-29 | アウトイフオンイ トヘラペウトイクス リミテッド | Ｋｖ３阻害剤としてのトリアゾール |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE58370B1 (en) * | 1985-04-10 | 1993-09-08 | Lundbeck & Co As H | Indole derivatives |
| GB8908085D0 (en) * | 1989-04-11 | 1989-05-24 | Lundbeck & Co As H | New therapeutic use |
| DK152090D0 (da) * | 1990-06-22 | 1990-06-22 | Lundbaek A S H | Piperidylsubstituerede indolderivater |
-
1993
- 1993-11-01 DK DK931234A patent/DK123493D0/da not_active Application Discontinuation
-
1994
- 1994-10-25 IL IL11139594A patent/IL111395A/xx not_active IP Right Cessation
- 1994-10-25 IL IL11139494A patent/IL111394A/en not_active IP Right Cessation
- 1994-10-28 ES ES94931520T patent/ES2154303T3/es not_active Expired - Lifetime
- 1994-10-28 WO PCT/DK1994/000407 patent/WO1995012591A1/en active IP Right Grant
- 1994-10-28 KR KR1019960702237A patent/KR100350550B1/ko not_active IP Right Cessation
- 1994-10-28 CA CA002175498A patent/CA2175498C/en not_active Expired - Fee Related
- 1994-10-28 JP JP51296895A patent/JP3898219B2/ja not_active Expired - Fee Related
- 1994-10-28 CZ CZ19961248A patent/CZ291403B6/cs not_active IP Right Cessation
- 1994-10-28 PL PL94314181A patent/PL176391B1/pl not_active IP Right Cessation
- 1994-10-28 PT PT94931520T patent/PT726898E/pt unknown
- 1994-10-28 HU HU9601144A patent/HUT76063A/hu not_active Application Discontinuation
- 1994-10-28 DE DE69426462T patent/DE69426462T2/de not_active Expired - Fee Related
- 1994-10-28 US US08/635,905 patent/US5703087A/en not_active Expired - Fee Related
- 1994-10-28 NZ NZ275086A patent/NZ275086A/en not_active IP Right Cessation
- 1994-10-28 AT AT94931520T patent/ATE198199T1/de not_active IP Right Cessation
- 1994-10-28 EP EP94931520A patent/EP0726898B1/en not_active Expired - Lifetime
- 1994-10-28 CN CN94193987A patent/CN1134149A/zh active Pending
- 1994-10-28 DK DK94931520T patent/DK0726898T3/da active
- 1994-10-28 RU RU96110902/04A patent/RU2156249C2/ru not_active IP Right Cessation
- 1994-10-28 AU AU80577/94A patent/AU683700B2/en not_active Ceased
- 1994-10-28 SI SI9430356T patent/SI0726898T1/xx unknown
- 1994-10-28 SK SK534-96A patent/SK281761B6/sk not_active IP Right Cessation
- 1994-11-01 ZA ZA948589A patent/ZA948589B/xx unknown
-
1996
- 1996-04-30 NO NO961746A patent/NO309038B1/no not_active IP Right Cessation
- 1996-04-30 FI FI961844A patent/FI116623B/fi active IP Right Grant
-
1998
- 1998-12-23 HK HK98115091A patent/HK1013817A1/xx not_active IP Right Cessation
-
2001
- 2001-02-22 GR GR20010400296T patent/GR3035462T3/el not_active IP Right Cessation
- 2001-12-20 LV LV010178A patent/LV12805B/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HUT69704A (en) | Isatin derivatives, process for the preparation thereof and pharmaceutical compositions comprising the same | |
| US5017573A (en) | Indazole-3-carboxylic acid derivatives | |
| FI116623B (fi) | Menetelmä uusien terapeuttisesti käyttökelpoisten fenyyli-indoliyhdisteiden valmistamiseksi | |
| EP0381422B1 (en) | Tetrahydrobenzimidazole derivatives | |
| PL172388B1 (pl) | Pochodne indolu PL PL PL PL PL PL PL PL PL | |
| US4153789A (en) | Phenylindolines | |
| JPH0873439A (ja) | １−ベンジル−１，３−ジヒドロ−２ｈ−ベンズイミダゾール−２−オン誘導体、これらの調製およびこれらを含有する薬学的組成物 | |
| US5317025A (en) | Piperidinylthioindole derivatives, their methods of preparation and pharmaceutical compositions in which they are present, useful especially as analgesics | |
| US5330986A (en) | Indole-7-carboxamide derivatives | |
| Ogawa et al. | Orally active, nonpeptide vasopressin V1 antagonists. A novel series of 1-(1-substituted 4-piperidyl)-3, 4-dihydro-2 (1H)-quinolinones | |
| US5344927A (en) | Tetrahydrobenzimidazole derivatives and pharmaceutical compositions containing same | |
| US5418242A (en) | Piperidinylthioindole derivatives, their methods of preparation and pharmaceutical compositions in which they are present, useful especially as analgesics | |
| CZ285028B6 (cs) | 3-substituované 1-arylindolové deriváty, jejich použití a farmaceutické prostředky s jejich obsahem | |
| US5496942A (en) | 5-substituted tetrahydrobenzimidazole compounds | |
| US7371769B2 (en) | Tetrahydropyridin-4-yl indoles with a combination of affinity for dopamine-D2 receptors and serotonin reuptake sites | |
| SK144095A3 (sk) | : Piperidinyltioindolové deriváty, spôsob ich prípravy a farmaceutické prostriedky obsahujúce tieto deriváty | |
| JPH09291090A (ja) | ピペリジノンおよびホモピペリジノン誘導体 | |
| DD291761A5 (de) | Verfahren zur herstellung von tetrahydrobenzimidazol-derivaten |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Patent granted |
Ref document number: 116623 Country of ref document: FI |