FI113770B - Menetelmä farmakologisesti aktiivisten 5-(2,3-dihydrobentsofuran-7-yyli)-7-hydroksi-3-metyyli-2,3,4,5-tetrahydro-1H-3-bentsatsepiinien valmistamiseksi - Google Patents

Menetelmä farmakologisesti aktiivisten 5-(2,3-dihydrobentsofuran-7-yyli)-7-hydroksi-3-metyyli-2,3,4,5-tetrahydro-1H-3-bentsatsepiinien valmistamiseksi Download PDF

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Publication number
FI113770B
FI113770B FI943875A FI943875A FI113770B FI 113770 B FI113770 B FI 113770B FI 943875 A FI943875 A FI 943875A FI 943875 A FI943875 A FI 943875A FI 113770 B FI113770 B FI 113770B
Authority
FI
Finland
Prior art keywords
compound
tetrahydro
formula
chloro
hydroxy
Prior art date
Application number
FI943875A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI943875A0 (fi
FI943875A (fi
Inventor
Rolf Hohlweg
Erik Bardrum Nielsen
Christian Foged
Original Assignee
Cenes Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cenes Ltd filed Critical Cenes Ltd
Publication of FI943875A0 publication Critical patent/FI943875A0/fi
Publication of FI943875A publication Critical patent/FI943875A/fi
Application granted granted Critical
Publication of FI113770B publication Critical patent/FI113770B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
FI943875A 1992-02-24 1994-08-23 Menetelmä farmakologisesti aktiivisten 5-(2,3-dihydrobentsofuran-7-yyli)-7-hydroksi-3-metyyli-2,3,4,5-tetrahydro-1H-3-bentsatsepiinien valmistamiseksi FI113770B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DK23392 1992-02-24
DK92233A DK23392D0 (da) 1992-02-24 1992-02-24 Heterocykliske forbindelser, deres anvendelse og fremstilling
DK9300041 1993-02-05
PCT/DK1993/000041 WO1993017012A1 (fr) 1992-02-24 1993-02-05 2,3,4,5-tetrahydro-1h-3-benzazepines et leurs sels d'addition d'acides acceptables sur le plan pharmaceutique

Publications (3)

Publication Number Publication Date
FI943875A0 FI943875A0 (fi) 1994-08-23
FI943875A FI943875A (fi) 1994-08-23
FI113770B true FI113770B (fi) 2004-06-15

Family

ID=8091236

Family Applications (1)

Application Number Title Priority Date Filing Date
FI943875A FI113770B (fi) 1992-02-24 1994-08-23 Menetelmä farmakologisesti aktiivisten 5-(2,3-dihydrobentsofuran-7-yyli)-7-hydroksi-3-metyyli-2,3,4,5-tetrahydro-1H-3-bentsatsepiinien valmistamiseksi

Country Status (23)

Country Link
EP (1) EP0628039B1 (fr)
JP (1) JPH07504172A (fr)
KR (1) KR100255739B1 (fr)
AT (1) ATE152450T1 (fr)
AU (1) AU667878B2 (fr)
BG (1) BG62208B1 (fr)
CA (1) CA2130678C (fr)
CZ (1) CZ288626B6 (fr)
DE (1) DE69310353T2 (fr)
DK (2) DK23392D0 (fr)
ES (1) ES2102019T3 (fr)
FI (1) FI113770B (fr)
GR (1) GR3023896T3 (fr)
HU (1) HU221314B1 (fr)
IL (1) IL104657A (fr)
NO (1) NO310193B1 (fr)
NZ (1) NZ249465A (fr)
RO (1) RO116088B1 (fr)
RU (1) RU2114839C1 (fr)
SK (1) SK281390B6 (fr)
UA (1) UA34451C2 (fr)
WO (1) WO1993017012A1 (fr)
ZA (1) ZA931099B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995025102A1 (fr) * 1994-03-16 1995-09-21 Novo Nordisk A/S Sels d'addition d'acide de composes de 2,3,4,5-tetrahydro-1h-3-benzazepine
CZ77898A3 (cs) * 1995-09-15 1998-07-15 Cenes Limited Kyselé adiční soli 2,3,4,5-tetrahydro-1H-3-benzazepinových sloučenin
GB0130576D0 (en) * 2001-12-20 2002-02-06 Cenes Ltd Dopamine D1 receptor agonist pro-drug compounds & derivatives
MX368959B (es) 2012-10-25 2019-10-23 Tetra Discovery Partners Llc Inhibidores heteroarilo de pde4.
US20150086480A1 (en) * 2013-09-26 2015-03-26 Tetra Discovery Partners, LLC Heteroaryl inhibitors of pde4

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK180485D0 (da) * 1985-04-22 1985-04-23 Novo Industri As Nitrogenholdige forbindelser
DK325188D0 (da) * 1988-06-15 1988-06-15 Novo Industri As Hidtil ukendte benzazepinderivater
DK67489D0 (da) * 1989-02-14 1989-02-14 Novo Industri As Nye benzazepinderivater

Also Published As

Publication number Publication date
RU94040719A (ru) 1996-07-10
NO943123D0 (no) 1994-08-24
RO116088B1 (ro) 2000-10-30
UA34451C2 (uk) 2001-03-15
HUT71127A (en) 1995-11-28
CZ288626B6 (cs) 2001-08-15
ES2102019T3 (es) 1997-07-16
HU9402434D0 (en) 1994-10-28
KR950700286A (ko) 1995-01-16
IL104657A0 (en) 1993-06-10
EP0628039B1 (fr) 1997-05-02
CA2130678A1 (fr) 1993-08-25
FI943875A0 (fi) 1994-08-23
CZ198894A3 (en) 1995-10-18
DK23392D0 (da) 1992-02-24
ZA931099B (en) 1994-08-17
SK281390B6 (sk) 2001-03-12
BG62208B1 (bg) 1999-05-31
CA2130678C (fr) 2004-04-20
NZ249465A (en) 1996-02-27
EP0628039A1 (fr) 1994-12-14
DE69310353T2 (de) 1997-10-02
RU2114839C1 (ru) 1998-07-10
FI943875A (fi) 1994-08-23
AU667878B2 (en) 1996-04-18
IL104657A (en) 1999-11-30
SK100094A3 (en) 1995-04-12
NO310193B1 (no) 2001-06-05
GR3023896T3 (en) 1997-09-30
DE69310353D1 (de) 1997-06-05
AU3626593A (en) 1993-09-13
NO943123L (no) 1994-08-24
HU221314B1 (en) 2002-09-28
JPH07504172A (ja) 1995-05-11
DK0628039T3 (da) 1997-12-08
WO1993017012A1 (fr) 1993-09-02
BG98993A (bg) 1995-05-31
KR100255739B1 (ko) 2000-05-01
ATE152450T1 (de) 1997-05-15

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