ES2102019T3 - 2,3,4,5-tetrahidro-1h-3-benzazepinas y sus sales de adicion farmaceuticamente aceptables. - Google Patents

2,3,4,5-tetrahidro-1h-3-benzazepinas y sus sales de adicion farmaceuticamente aceptables.

Info

Publication number
ES2102019T3
ES2102019T3 ES93905215T ES93905215T ES2102019T3 ES 2102019 T3 ES2102019 T3 ES 2102019T3 ES 93905215 T ES93905215 T ES 93905215T ES 93905215 T ES93905215 T ES 93905215T ES 2102019 T3 ES2102019 T3 ES 2102019T3
Authority
ES
Spain
Prior art keywords
benzazepinas
tetrahidro
pharmaceutically acceptable
additional salts
acceptable additional
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93905215T
Other languages
English (en)
Inventor
Christian Foged
Rolf Hohlweg
Erik Bardrum Nielsen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Application granted granted Critical
Publication of ES2102019T3 publication Critical patent/ES2102019T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

SE PRESENTAN 2,3,4,5-TETRAHIDRO-1H-3-BENZACEPINAS QUE TIENEN LA FORMULA GENERAL (I) EN DONDE R1 ES CL O BR; R3 Y R4 SON HIDROGENO, HALOGENO, CF3, CN, NO2, O NH2. LOS COMPUESTOS SON UTILES EN EL TRATAMIENTO DE CIERTAS ENFERMEDADES DEL SISTEMA NERVIOSO CENTRAL.
ES93905215T 1992-02-24 1993-02-05 2,3,4,5-tetrahidro-1h-3-benzazepinas y sus sales de adicion farmaceuticamente aceptables. Expired - Lifetime ES2102019T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK92233A DK23392D0 (da) 1992-02-24 1992-02-24 Heterocykliske forbindelser, deres anvendelse og fremstilling

Publications (1)

Publication Number Publication Date
ES2102019T3 true ES2102019T3 (es) 1997-07-16

Family

ID=8091236

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93905215T Expired - Lifetime ES2102019T3 (es) 1992-02-24 1993-02-05 2,3,4,5-tetrahidro-1h-3-benzazepinas y sus sales de adicion farmaceuticamente aceptables.

Country Status (23)

Country Link
EP (1) EP0628039B1 (es)
JP (1) JPH07504172A (es)
KR (1) KR100255739B1 (es)
AT (1) ATE152450T1 (es)
AU (1) AU667878B2 (es)
BG (1) BG62208B1 (es)
CA (1) CA2130678C (es)
CZ (1) CZ288626B6 (es)
DE (1) DE69310353T2 (es)
DK (2) DK23392D0 (es)
ES (1) ES2102019T3 (es)
FI (1) FI113770B (es)
GR (1) GR3023896T3 (es)
HU (1) HU221314B1 (es)
IL (1) IL104657A (es)
NO (1) NO310193B1 (es)
NZ (1) NZ249465A (es)
RO (1) RO116088B1 (es)
RU (1) RU2114839C1 (es)
SK (1) SK281390B6 (es)
UA (1) UA34451C2 (es)
WO (1) WO1993017012A1 (es)
ZA (1) ZA931099B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1945495A (en) * 1994-03-16 1995-10-03 Novo Nordisk A/S Acid addition salts of 2,3,4,5-tetrahydro-1h-3-benzazepine compounds
EP0850237A1 (en) * 1995-09-15 1998-07-01 Novo Nordisk A/S Acid addition salts of 2,3,4,5-tetrahydro-1h-3-benzazepine compounds
GB0130576D0 (en) * 2001-12-20 2002-02-06 Cenes Ltd Dopamine D1 receptor agonist pro-drug compounds & derivatives
MX368959B (es) 2012-10-25 2019-10-23 Tetra Discovery Partners Llc Inhibidores heteroarilo de pde4.
US20150086480A1 (en) * 2013-09-26 2015-03-26 Tetra Discovery Partners, LLC Heteroaryl inhibitors of pde4

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK180485D0 (da) * 1985-04-22 1985-04-23 Novo Industri As Nitrogenholdige forbindelser
DK325188D0 (da) * 1988-06-15 1988-06-15 Novo Industri As Hidtil ukendte benzazepinderivater
DK67489D0 (da) * 1989-02-14 1989-02-14 Novo Industri As Nye benzazepinderivater

Also Published As

Publication number Publication date
KR100255739B1 (ko) 2000-05-01
NZ249465A (en) 1996-02-27
EP0628039A1 (en) 1994-12-14
IL104657A0 (en) 1993-06-10
EP0628039B1 (en) 1997-05-02
FI943875A0 (fi) 1994-08-23
CZ288626B6 (cs) 2001-08-15
CZ198894A3 (en) 1995-10-18
FI943875A (fi) 1994-08-23
NO310193B1 (no) 2001-06-05
DK0628039T3 (da) 1997-12-08
CA2130678A1 (en) 1993-08-25
HU221314B1 (en) 2002-09-28
CA2130678C (en) 2004-04-20
ATE152450T1 (de) 1997-05-15
RU2114839C1 (ru) 1998-07-10
UA34451C2 (uk) 2001-03-15
HU9402434D0 (en) 1994-10-28
IL104657A (en) 1999-11-30
DK23392D0 (da) 1992-02-24
BG98993A (bg) 1995-05-31
DE69310353D1 (de) 1997-06-05
ZA931099B (en) 1994-08-17
DE69310353T2 (de) 1997-10-02
FI113770B (fi) 2004-06-15
KR950700286A (ko) 1995-01-16
JPH07504172A (ja) 1995-05-11
BG62208B1 (bg) 1999-05-31
SK100094A3 (en) 1995-04-12
RO116088B1 (ro) 2000-10-30
NO943123D0 (no) 1994-08-24
WO1993017012A1 (en) 1993-09-02
AU667878B2 (en) 1996-04-18
NO943123L (no) 1994-08-24
GR3023896T3 (en) 1997-09-30
SK281390B6 (sk) 2001-03-12
HUT71127A (en) 1995-11-28
AU3626593A (en) 1993-09-13
RU94040719A (ru) 1996-07-10

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ES2102019T3 (es) 2,3,4,5-tetrahidro-1h-3-benzazepinas y sus sales de adicion farmaceuticamente aceptables.

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