RU94040719A - 2,3,4,5-тетрагидро-1h-3-бензазепины, фармацевтическая композиция, способ лечения и способ получения - Google Patents

2,3,4,5-тетрагидро-1h-3-бензазепины, фармацевтическая композиция, способ лечения и способ получения

Info

Publication number
RU94040719A
RU94040719A RU94040719/04A RU94040719A RU94040719A RU 94040719 A RU94040719 A RU 94040719A RU 94040719/04 A RU94040719/04 A RU 94040719/04A RU 94040719 A RU94040719 A RU 94040719A RU 94040719 A RU94040719 A RU 94040719A
Authority
RU
Russia
Prior art keywords
tetrahydro
benzazepine
pharmaceutical composition
preparation process
benzazepines
Prior art date
Application number
RU94040719/04A
Other languages
English (en)
Other versions
RU2114839C1 (ru
Inventor
Фогед Кристиан
Dk]
Холвег Рольф
Бардрум Нильсен Эрик
De]
Original Assignee
Ново Нордиск А/С (DK)
Ново Нордиск А/С
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ново Нордиск А/С (DK), Ново Нордиск А/С filed Critical Ново Нордиск А/С (DK)
Publication of RU94040719A publication Critical patent/RU94040719A/ru
Application granted granted Critical
Publication of RU2114839C1 publication Critical patent/RU2114839C1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Описываются 2,3,4,5-тетрагидро-1Н-3-бензазепины общей формулы, приведенной в описании. Данные соединения полезны при лечении различных расстройств центральной нервной системы.

Claims (1)

  1. Описываются 2,3,4,5-тетрагидро-1Н-3-бензазепины общей формулы, приведенной в описании. Данные соединения полезны при лечении различных расстройств центральной нервной системы.
RU94040719A 1992-02-24 1993-02-05 2,3,4,5-тетрагидро-1н-3-бензазепины, фармацевтическая композиция, способ лечения и способы получения RU2114839C1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK92233A DK23392D0 (da) 1992-02-24 1992-02-24 Heterocykliske forbindelser, deres anvendelse og fremstilling
DK0233/92 1992-02-24

Publications (2)

Publication Number Publication Date
RU94040719A true RU94040719A (ru) 1996-07-10
RU2114839C1 RU2114839C1 (ru) 1998-07-10

Family

ID=8091236

Family Applications (1)

Application Number Title Priority Date Filing Date
RU94040719A RU2114839C1 (ru) 1992-02-24 1993-02-05 2,3,4,5-тетрагидро-1н-3-бензазепины, фармацевтическая композиция, способ лечения и способы получения

Country Status (23)

Country Link
EP (1) EP0628039B1 (ru)
JP (1) JPH07504172A (ru)
KR (1) KR100255739B1 (ru)
AT (1) ATE152450T1 (ru)
AU (1) AU667878B2 (ru)
BG (1) BG62208B1 (ru)
CA (1) CA2130678C (ru)
CZ (1) CZ288626B6 (ru)
DE (1) DE69310353T2 (ru)
DK (2) DK23392D0 (ru)
ES (1) ES2102019T3 (ru)
FI (1) FI113770B (ru)
GR (1) GR3023896T3 (ru)
HU (1) HU221314B1 (ru)
IL (1) IL104657A (ru)
NO (1) NO310193B1 (ru)
NZ (1) NZ249465A (ru)
RO (1) RO116088B1 (ru)
RU (1) RU2114839C1 (ru)
SK (1) SK281390B6 (ru)
UA (1) UA34451C2 (ru)
WO (1) WO1993017012A1 (ru)
ZA (1) ZA931099B (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0750616T3 (da) * 1994-03-16 2001-07-23 Cenes Ltd Syreadditionssalte af 2,3,4,5-tetrahydro-1H-3-benzazapinforbindelser
AU700596B2 (en) * 1995-09-15 1999-01-07 Cenes Limited Acid addition salts of 2,3,4,5-tetrahydro-1H-3-benzazepine compounds
GB0130576D0 (en) * 2001-12-20 2002-02-06 Cenes Ltd Dopamine D1 receptor agonist pro-drug compounds & derivatives
DK2912019T3 (da) 2012-10-25 2021-05-25 Tetra Discovery Partners Llc Heteroarylhæmmere af pde4
US20150086480A1 (en) * 2013-09-26 2015-03-26 Tetra Discovery Partners, LLC Heteroaryl inhibitors of pde4

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK180485D0 (da) * 1985-04-22 1985-04-23 Novo Industri As Nitrogenholdige forbindelser
DK325188D0 (da) * 1988-06-15 1988-06-15 Novo Industri As Hidtil ukendte benzazepinderivater
DK67489D0 (da) * 1989-02-14 1989-02-14 Novo Industri As Nye benzazepinderivater

Also Published As

Publication number Publication date
IL104657A0 (en) 1993-06-10
ES2102019T3 (es) 1997-07-16
BG62208B1 (bg) 1999-05-31
DE69310353D1 (de) 1997-06-05
HUT71127A (en) 1995-11-28
FI943875A (fi) 1994-08-23
ZA931099B (en) 1994-08-17
ATE152450T1 (de) 1997-05-15
NO943123L (no) 1994-08-24
AU3626593A (en) 1993-09-13
SK281390B6 (sk) 2001-03-12
DK0628039T3 (da) 1997-12-08
KR950700286A (ko) 1995-01-16
UA34451C2 (ru) 2001-03-15
DE69310353T2 (de) 1997-10-02
IL104657A (en) 1999-11-30
RO116088B1 (ro) 2000-10-30
DK23392D0 (da) 1992-02-24
NO943123D0 (no) 1994-08-24
CA2130678A1 (en) 1993-08-25
GR3023896T3 (en) 1997-09-30
RU2114839C1 (ru) 1998-07-10
KR100255739B1 (ko) 2000-05-01
EP0628039B1 (en) 1997-05-02
WO1993017012A1 (en) 1993-09-02
EP0628039A1 (en) 1994-12-14
HU9402434D0 (en) 1994-10-28
CA2130678C (en) 2004-04-20
FI943875A0 (fi) 1994-08-23
JPH07504172A (ja) 1995-05-11
NZ249465A (en) 1996-02-27
HU221314B1 (en) 2002-09-28
SK100094A3 (en) 1995-04-12
AU667878B2 (en) 1996-04-18
BG98993A (bg) 1995-05-31
CZ198894A3 (en) 1995-10-18
CZ288626B6 (cs) 2001-08-15
FI113770B (fi) 2004-06-15
NO310193B1 (no) 2001-06-05

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Legal Events

Date Code Title Description
MM4A The patent is invalid due to non-payment of fees

Effective date: 20050206