MX9703846A - Nuevos derivados de 10, 11-dihidro-10-oxo-5h-dibenz/b, f/azepina-5-carboxamida. - Google Patents

Nuevos derivados de 10, 11-dihidro-10-oxo-5h-dibenz/b, f/azepina-5-carboxamida.

Info

Publication number
MX9703846A
MX9703846A MX9703846A MX9703846A MX9703846A MX 9703846 A MX9703846 A MX 9703846A MX 9703846 A MX9703846 A MX 9703846A MX 9703846 A MX9703846 A MX 9703846A MX 9703846 A MX9703846 A MX 9703846A
Authority
MX
Mexico
Prior art keywords
asephine
diydro
dibenz
oxo
novel
Prior art date
Application number
MX9703846A
Other languages
English (en)
Other versions
MXPA97003846A (es
Inventor
Jan Benes
Patricio Manuel Vieira A Soare
S Da Silva
David Alexander Learmonth
Original Assignee
Portela & Ca Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Portela & Ca Sa filed Critical Portela & Ca Sa
Publication of MX9703846A publication Critical patent/MX9703846A/es
Publication of MXPA97003846A publication Critical patent/MXPA97003846A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C07D223/30—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hetero atoms directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

Se describen los compuestos de la formula general I: así como un proceso para su preparacion el cual consiste en la reaccion de un compuesto de la formula II: con hidroxilamina o sus derivados de la formula III: H2NOR2 (III). Los compuestos citados en la presente invencion tienen valiosas propiedades farmacéuticas es decir en el tratamiento de algunas perturbaciones en el sistema nervioso central y periférico.
MXPA/A/1997/003846A 1996-05-27 1997-05-26 Nuevos derivados de 10, 11-dihidro-10-oxo-5h-dibenz/b, f/azepina-5-carboxamida MXPA97003846A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PT101876A PT101876B (pt) 1996-05-27 1996-05-27 Novos derivados de 10,11-di-hidro-10-oxo-5h-dibenzo(b,f)azepina-5-carboxamida
PT101,876 1996-05-27

Publications (2)

Publication Number Publication Date
MX9703846A true MX9703846A (es) 1998-06-30
MXPA97003846A MXPA97003846A (es) 1998-10-30

Family

ID=

Also Published As

Publication number Publication date
PL189298B1 (pl) 2005-07-29
RU2187503C2 (ru) 2002-08-20
ES2156319T3 (es) 2001-06-16
CA2206172A1 (en) 1997-11-27
EP0810216A1 (en) 1997-12-03
PT101876A (pt) 1997-12-31
SI0810216T1 (es) 2001-08-31
PL330141A1 (en) 1999-04-26
DE69704297D1 (de) 2001-04-26
GR3035910T3 (en) 2001-08-31
PT101876B (pt) 1999-09-30
EP0810216B1 (en) 2001-03-21
BR9703403B1 (pt) 2010-06-29
DK0810216T3 (da) 2001-07-23
AR007291A1 (es) 1999-10-27
BR9703403A (pt) 1998-09-15
JPH1081669A (ja) 1998-03-31
ATE199901T1 (de) 2001-04-15
WO1997045416A1 (en) 1997-12-04
CA2206172C (en) 2002-07-16
DE69704297T2 (de) 2001-09-20
JP3592892B2 (ja) 2004-11-24
TR199802462T2 (xx) 2000-07-21
AU2974097A (en) 1998-01-05
CN1226234A (zh) 1999-08-18
US5866566A (en) 1999-02-02
AU713807B2 (en) 1999-12-09
CN1101382C (zh) 2003-02-12

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Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees